FAAH
L'hydrolase des amides d'acides gras (FAAH) est une enzyme qui décompose les amides d'acides gras, y compris les endocannabinoïdes comme l'anandamide. Ces composés sont impliqués dans la régulation de la douleur, de l'humeur, de l'appétit et de la mémoire. L'inhibition de la FAAH peut augmenter les niveaux de ces molécules de signalisation, offrant ainsi des bénéfices thérapeutiques potentiels pour la douleur, l'anxiété et les maladies neurodégénératives. Chez CymitQuimica, nous proposons une sélection d'inhibiteurs de la FAAH pour soutenir vos recherches en neurosciences, gestion de la douleur et signalisation endocannabinoïde.
Produits appartenant à la catégorie "FAAH"
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43 produits dans cette catégorie.
AM 374
CAS :AM 374 (HDSF), a fatty acid amide hydrolase (FAAH) inhibitor, demonstrates the capacity to inhibit amidase activity, boasting an IC50 value of 13 nM.Formule :C16H33FO2SDegré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :308.5FAAH-IN-1
CAS :FAAH-IN-1 is a fatty acid amide hydrolase (FAAH) inhibitor, with IC50s of 145 nM and 650 nM for rat and human FAAH, respectively.Formule :C20H19ClN4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.91N-Benzylpalmitamide
CAS :N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for theFormule :C23H39NODegré de pureté :97.08% - 99.77%Couleur et forme :SolidMasse moléculaire :345.56PF-04457845
CAS :PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).Formule :C23H20F3N5O2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :455.43Ref: TM-T4323
2mg35,00€5mg52,00€10mg88,00€25mg163,00€50mg235,00€100mg419,00€200mg545,00€1mL*10mM (DMSO)58,00€LY2183240
CAS :LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM).Formule :C17H17N5ODegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :307.35JP104
CAS :JP104 is an aryl carbamate that irreversibly inhibits fatty acid amide hydrolase (FAAH) with a pIC50 value of approximately 8 [1].Formule :C25H30N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.52AA38-3
CAS :AA38-3 (1-Piperidinecarboxylic acid, 4-nitrophenyl ester) inhibites three SHs (ABHD6, ABHD11, and FAAH)Formule :C12H14N2O4Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :250.25URB-597
CAS :URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.Formule :C20H22N2O3Degré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :338.4N-(3-Methoxybenzyl)Palmitamide
CAS :N-(3-Methoxybenzyl)Palmitamide is a promising FAAH inhibitor, treatment of pain, inflammation and CNS degenerative disorders.Formule :C24H41NO2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :375.59MAGL-IN-5
CAS :MAGL-IN-5 is a non-selective lipase inhibitor.Formule :C18H17N3O5Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :355.34Ref: TM-T9967
1mg35,00€5mg70,00€10mg96,00€25mg202,00€50mg323,00€100mg512,00€200mg738,00€1mL*10mM (DMSO)81,00€OMDM-1
CAS :OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) is a selective and metabolically stable anandamide cellular uptake (ACU)Formule :C27H45NO3Degré de pureté :97.88%Couleur et forme :SolidMasse moléculaire :431.65PF 750
CAS :PF 750 (ZINC27647189) is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.Formule :C22H23N3ODegré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :345.44Ref: TM-T16515
2mg39,00€5mg62,00€10mg87,00€25mg187,00€50mg298,00€100mg444,00€200mg635,00€500mg938,00€1mL*10mM (DMSO)67,00€URB937
CAS :URB937 is an inhibitor of FAAH and increases anandamide levels(IC50 : 26.8 nM).Formule :C20H22N2O4Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :354.4FAAH-IN-2
CAS :FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is a potent inhibitor of FAAH(fatty acid amide hydrolase).Formule :C15H11ClFN3O2Degré de pureté :99.18%Couleur et forme :Tan SolidMasse moléculaire :319.72MK-4409
CAS :MK-4409, a potent and selective fatty acid amide hydrolase (FAAH) inhibitor, is being investigated for the treatment of inflammatory and neuropathic pain.Formule :C22H17ClFN3O2SDegré de pureté :99.70% - 99.81%Couleur et forme :SolidMasse moléculaire :441.911-Monomyristin
CAS :1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterialFormule :C17H34O4Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :302.45JZL195
CAS :JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.Formule :C24H23N3O5Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :433.46SA57
CAS :SA57 is a potent, selective inhibitor of FAAH(IC50s of 3.2 nM and 1.9 nM for mouse and human FAAH).Formule :C17H23ClN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.83Isopropyl dodec-11-enylfluorophosphonate
CAS :Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist and exhibitsFormule :C15H30FO2PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.37BIA 10-2474
CAS :BIA 10-2474 is a long-acting reversible inhibitor of FAAH that increases levels of the neurotransmitter anandamide in the nervous system.Formule :C16H20N4O2Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :300.36PDP-EA
CAS :PDP-EA is an activator of fatty acid amide hydrolase(FAAH) and enhances the amidohydrolase activity of FAAH.Formule :C25H43NO3Degré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :405.61OMDM-5
CAS :OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).Formule :C26H44N2O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :432.64Ref: TM-T12306
1mg87,00€5mg187,00€10mg284,00€25mg452,00€50mg645,00€100mg867,00€200mg1.130,00€1mL*10mM (DMSO)221,00€FAAH inhibitor 1
CAS :FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.Formule :C24H23N3O3S3Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :497.65Ref: TM-T11256
1mg52,00€5mg116,00€10mg182,00€25mg306,00€50mg442,00€100mg620,00€200mg835,00€1mL*10mM (DMSO)128,00€ARN272
CAS :ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM).Formule :C27H20N4O2Degré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :432.47MAGL-IN-4
CAS :MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.Formule :C18H21ClN2O4Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :364.82Ref: TM-T9687
1mg140,00€5mg344,00€10mg512,00€25mg848,00€50mg1.121,00€100mg1.510,00€1mL*10mM (DMSO)373,00€VU534
CAS :VU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases relatedFormule :C21H22FN3O3S2Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :447.55Sob-AM2
CAS :Sob-AM2 is an effective substrate targeting the fatty acid amide hydrolase (FAAH) expressed in the brain, with a Km of 1.3 μM. It delivers higher concentrations of Sobetirome to the central nervous system at minimal peripheral systemic doses, thereby activating the central thyroid hormone receptor β (TRβ).Formule :C21H27NO3Couleur et forme :SolidMasse moléculaire :341.44JNJ-1661010
CAS :JNJ-1661010 (Takeda-25) is an effective and specific FAAH inhibitor (IC50: 10/ 12 nM for rat/human), shows >100-fold selectivity for FAAH-1 than FAAH-2.Formule :C19H19N5OSDegré de pureté :99.79% - 99.97%Couleur et forme :SolidMasse moléculaire :365.454-Nonylphenylboronic acid
CAS :4-Nonylphenylboronic acid is a inhibitor of FAAH.Formule :C15H25BO2Degré de pureté :97.63%Couleur et forme :SolidMasse moléculaire :248.17Biochanin A
CAS :Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.Formule :C16H12O5Degré de pureté :97.1% - 98.97%Couleur et forme :SolidMasse moléculaire :284.26N-Benzyllinolenamide
CAS :N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).Formule :C25H37NODegré de pureté :98.00% - 99.92%Couleur et forme :SolidMasse moléculaire :367.57Ref: TM-TN1965
1mg88,00€5mg187,00€10mg281,00€25mg475,00€50mg692,00€100mg935,00€200mg1.264,00€1mL*10mM (DMSO)188,00€JNJ-40355003
CAS :JNJ-40355003 is a FAAH inhibitor that increases plasma levels of fatty acid amides in rats, dogs, and crabs.Formule :C23H23ClN4O2Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :422.91MK-3168 (12C)
CAS :MK-3168 (12C) functions as a FAAH inhibitor, exhibiting IC50 values of 1.0 nM, 5.5 nM, and 1.7 nM for human, rhesus, and rat respectively. It demonstrates effective brain uptake and FAAH-specific signaling. Additionally, 11 C MK-3168 is applicable as a FAAH PET tracer.Formule :C21H21ClN4OSCouleur et forme :SolidMasse moléculaire :412.94Palmitoylisopropylamide
CAS :Palmitoylisopropylamide is a selective FAAH inhibitor that inhibits [H]-AEA uptake and cell proliferation at low concentrations.Formule :C19H39NODegré de pureté :100%Couleur et forme :SolidMasse moléculaire :297.52WWL 154
CAS :WWL 154 is an serine hydrolase (SH) and fatty acid amide hydrolase FAAH-4 inhibitor.Formule :C18H19N3O5Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :357.36Ref: TM-T8927
1mg46,00€5mg84,00€10mg106,00€25mg150,00€50mg207,00€100mg311,00€200mg444,00€1mL*10mM (DMSO)85,00€BuChE-IN-15
BuChE-IN-15, a chemical compound, exhibits potent inhibitory activity with IC50 values of 81 nM and 400 nM, respectively. It also demonstrates good blood-brain barrier permeability and neuroprotective properties, making it suitable for research in Alzheimer's disease.Formule :C18H18FNO4Couleur et forme :SolidMasse moléculaire :331.34PF-3845
CAS :PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.Formule :C24H23F3N4O2Degré de pureté :99.54% - 99.58%Couleur et forme :SolidMasse moléculaire :456.46Ref: TM-T6043
2mg42,00€5mg59,00€10mg97,00€25mg205,00€50mg354,00€100mg560,00€200mg800,00€1mL*10mM (DMSO)59,00€SA 47
CAS :SA 47 is a selective and effective inhibitor of fatty acid amide hydrolase and carbamate.Formule :C17H26N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :334.41Carprofen
CAS :Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities.Formule :C15H12ClNO2Degré de pureté :98.99% - 99.65%Couleur et forme :SolidMasse moléculaire :273.71JNJ-42165279
CAS :JNJ-42165279 selectively inactivates FAAH without notably affecting other enzymes, ion channels, receptors, or CYPs/hERG at 10 μM.Formule :C18H17ClF2N4O3Degré de pureté :99.88% - 99.89%Couleur et forme :SolidMasse moléculaire :410.8Ref: TM-T3215
2mg46,00€5mg65,00€10mg96,00€25mg170,00€50mg246,00€100mg363,00€200mg512,00€1mL*10mM (DMSO)75,00€MM-433593
CAS :MM-433593 is a selective fatty acid amide hydrolase (FAAH-1) inhibitor for the treatment of pain, inflammation, and other disorders.Formule :C25H22ClN3O3Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :447.91Dual FAAH/sEH-IN-1
CAS :Dual FAAH/sEH-IN-1 inhibits both sEH (IC50: 9.6 nM) and FAAH (IC50: 7 nM), offering potent anti-inflammatory effects.Formule :C25H22ClN3O3S2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :512.04Ref: TM-T63536
1mg140,00€5mg331,00€10mg439,00€25mg667,00€50mg894,00€100mg1.198,00€200mg1.596,00€1mL*10mM (DMSO)406,00€2-Chlorophenylboronic acid
CAS :2-Chlorophenylboronic acid: A monohalogenated phenylboronic acid used in drug synthesis and as a fatty acid amidase inhibitor.Formule :C6H6BClO2Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :156.37
