NAMPT
La nicotinamide phosphoribosyltransférase (NAMPT) est une enzyme impliquée dans la biosynthèse du nicotinamide adénine dinucléotide (NAD+), un coenzyme essentiel au métabolisme cellulaire et à la production d'énergie. Les inhibiteurs de la NAMPT suscitent un intérêt particulier en recherche sur le cancer, en raison de leur capacité à perturber le métabolisme du NAD+ et à induire la mort des cellules cancéreuses. Ces inhibiteurs sont également étudiés dans le contexte des troubles métaboliques et du vieillissement. Chez CymitQuimica, nous proposons des inhibiteurs de la NAMPT pour soutenir vos recherches en biologie du cancer, métabolisme et vieillissement.
Produits appartenant à la catégorie "NAMPT"
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20 produits dans cette catégorie.
GNE-617
CAS :GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer.Formule :C21H15F2N3O3SDegré de pureté :99.28% - 99.97%Couleur et forme :SolidMasse moléculaire :427.42Ref: TM-T4335
1mg40,00€2mg52,00€5mg85,00€10mg124,00€25mg219,00€50mg350,00€100mg522,00€500mg1.130,00€1mL*10mM (DMSO)86,00€Nampt-IN-14
CAS :Nampt-IN-14 (example 3) is an effective NAMPT inhibitor with an IC50 of 0.2 nM, suited for use in the synthesis of antibody-drug conjugates (ADCs).Formule :C33H35N7O2Couleur et forme :SolidMasse moléculaire :561.68CHS-828
CAS :CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).Formule :C19H22ClN5ODegré de pureté :100% - 99.76%Couleur et forme :SolidMasse moléculaire :371.86(E)-Daporinad
CAS :(E)-Daporinad (FK866) is a highly specific, non-competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .Cost-effective and quality-assured.Formule :C24H29N3O2Degré de pureté :100% - 99.96%Couleur et forme :SolidMasse moléculaire :391.51Ref: TM-T2644
2mg43,00€5mg65,00€10mg96,00€25mg188,00€50mg368,00€100mg557,00€500mg1.169,00€1mL*10mM (DMSO)70,00€STF-118804
CAS :STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.Formule :C25H23N3O4SDegré de pureté :98.66%Couleur et forme :SolidMasse moléculaire :461.53Nampt-IN-5
CAS :Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .Formule :C25H25N5O2Degré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :427.5Ref: TM-T12171
1mg81,00€5mg156,00€10mg264,00€25mg419,00€50mg562,00€100mg775,00€200mg1.026,00€1mL*10mM (DMSO)170,00€Nampt activator-1
CAS :NAMPT Activator-1, EC50: 3.3-3.7 µM, specific niacinamide phosphotransferase stimulant, shields cells, potential neuroprotectant.Formule :C16H17N3O3Degré de pureté :99.98% - 99.98%Couleur et forme :SoildMasse moléculaire :299.32LB-60-OF61
CAS :LB-60-OF61 is a NAMPT inhibitor, a NAMPT inhibitor that displays antiproliferative activity against MYC oncogene-dependent cancer cell lines.Formule :C29H30N6O2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :494.59Ref: TM-T11823
1mg162,00€5mg393,00€10mg645,00€25mg1.254,00€50mg2.118,00€100mg3.307,00€1mL*10mM (DMSO)425,00€Nampt-IN-15
CAS :Nampt-IN-15 (Example 3) is a Nampt inhibitor that exhibits cytotoxic effects on various cell lines, including BxPC-3, HepG2, L540cy, and MOLM-13. The respective IC50 values for these cell lines are 38.5 nM, 8 nM, 8.5 nM, and 7 nM.Formule :C24H30N4O2Couleur et forme :SolidMasse moléculaire :406.52Nampt-IN-13
CAS :Nampt-IN-13 (example 58m) is an NAMPT inhibitor used in the synthesis of antibody-drug conjugates (ADCs).Formule :C24H30N6O2Couleur et forme :SolidMasse moléculaire :434.53CB30865
CAS :CB30865 (ZM 242421) is a selective and highly effective nicotinamide phosphoribosyltransferase (Nampt) inhibitor with potential antitumor activity.Formule :C26H22BrN5O2Degré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :516.39NAMPT Protein, Human, Recombinant (His)
Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, butDegré de pureté :94% - 94%Couleur et forme :Lyophilized PowderMasse moléculaire :55 KDa (reducing condition)Nampt-IN-1
CAS :Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.Formule :C20H25N3O5SDegré de pureté :96.82% - 99.4%Couleur et forme :SolidMasse moléculaire :419.49Ref: TM-T4376
1mg39,00€2mg52,00€5mg84,00€10mg137,00€25mg259,00€50mg432,00€100mg638,00€1mL*10mM (DMSO)92,00€NAMPT degrader-3
NAMPT Degrader-3 (compound C5) is a NAMPT degrader that functions through a VHL- and proteasome-dependent mechanism.Formule :C56H74N8O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1003.3SBI-797812
CAS :SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).Formule :C19H22N4O4SDegré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :402.47Ref: TM-T12854
1mg59,00€5mg120,00€10mg212,00€25mg369,00€50mg593,00€100mg932,00€200mg1.264,00€1mL*10mM (DMSO)105,00€Teglarinad chloride
CAS :Teglarinad chloride (GMX-1777 chloride) is an inhibitor of NAMPT with antitumor activity that acts by interfering with DNA repair and inhibiting angiogenesis.Formule :C30H43Cl2N5O8Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :672.6OT-82
CAS :OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.Formule :C26H21FN4ODegré de pureté :98.91% - 98.91%Couleur et forme :SolidMasse moléculaire :424.47KPT9274
CAS :KPT9274 (PAK4-IN-1) is a non-competitive dual inhibitor of PAK4 and NAMPT(IC50= ~120 nM). It is an orally bioavailable small molecule.Formule :C35H29F3N4O3Degré de pureté :99.75% - 99.93%Couleur et forme :SolidMasse moléculaire :610.62GNE-618
CAS :GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM).Formule :C21H15F3N4O3SCouleur et forme :SolidMasse moléculaire :460.43ALT-100 (Human IgG1)
ALT-100 (HumanIgG1) is a human-derived IgG1 monoclonal antibody that targets NAMPT. For its isotype control, please refer to HumanIgG1kappa, Isotype Control.Couleur et forme :Odour Liquid
