Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
Produits appartenant à la catégorie "Déshydrogénase"
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SCD1 inhibitor-3
CAS :SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.Formule :C19H16FN7O2Degré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :393.37Ref: TM-T38683
1mg92,00€5mg187,00€10mg298,00€25mg507,00€50mg730,00€100mg1.026,00€1mL*10mM (DMSO)205,00€(E/Z)-Ginkgolic acid C17:2
CAS :(E/Z)-Ginkgolic acid C17:2 (Ginkgolic Acid C17:2) is a natural product that can be extracted from Ginkgo biloba and targets human dihydroorotic acidFormule :C24H36O3Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :372.54PF-915275
CAS :PF-915275 inhibits 11βHSD1 in humans (Ki=2.3 nM, EC50=15 nM) and affects cortisone-cortisol conversion in hepatocytes.Formule :C18H14N4O2SDegré de pureté :97.69% - 98.62%Couleur et forme :SolidMasse moléculaire :350.39Ref: TM-T16510
1mg38,00€2mg49,00€5mg81,00€10mg127,00€25mg255,00€50mg499,00€100mg723,00€500mg1.510,00€1mL*10mM (DMSO)89,00€AZD 4017
CAS :AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).Formule :C22H33N3O3SDegré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :419.58Ref: TM-T14388
1mg73,00€5mg160,00€10mg274,00€25mg550,00€50mg792,00€100mg1.093,00€1mL*10mM (DMSO)170,00€Dihydrouracil
CAS :5,6-Dihydrouracil (5,6-Dihydrouracil) is an intermediate breakdown product of uracil.Formule :C4H6N2O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :114.1Vidofludimus
CAS :Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).Formule :C20H18FNO4Degré de pureté :98.83% - 99.58%Couleur et forme :SolidMasse moléculaire :355.36AVN-944
CAS :AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.Formule :C25H27N5O5Degré de pureté :99.07% - ≥95%Couleur et forme :SolidMasse moléculaire :477.5111β-HSD1 inibitor 19
CAS :3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.Formule :C19H16ClF4N3O2SDegré de pureté :99.46%Couleur et forme :SoildMasse moléculaire :461.86Glomeratose A
CAS :Glomeratose A is a lactate dehydrogenase inhibitor.Formule :C24H34O15Degré de pureté :98% - 99.67%Couleur et forme :SolidMasse moléculaire :562.52Nitrofen
CAS :Nitrofen is a selective contact herbicide. Nitrofen is a protoporphyrinogen oxidase and retinal dehydrogenase inhibitor.Formule :C12H7Cl2NO3Degré de pureté :99.92%Couleur et forme :Less Crystals Or Black Solid Used As A Pre- Or Post-Emergence HerbicideMasse moléculaire :284.09G6PD activator AG1
CAS :G6PD activator AG1 is a G6PD agonist that promotes G6PD oligomerization to a catalytically competent form.Formule :C24H30N4S2Degré de pureté :98.38% - 99.51%Couleur et forme :SolidMasse moléculaire :438.65GSK321
CAS :GSK321 is an IDH1 inhibitor that prevents cytoplasmic glutamine reductive carboxylation.GSK321 is used in the study of leukemia.Formule :C28H28FN5O3Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :501.55GSK864
CAS :GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).Formule :C30H31FN6O4Degré de pureté :97.07%Couleur et forme :SolidMasse moléculaire :558.6Trilostane
CAS :Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties.Formule :C20H27NO3Degré de pureté :100% - 99.46%Couleur et forme :Tan CrystalsMasse moléculaire :329.43CBR-5884
CAS :CBR-5884: active PHGDH inhibitor, IC50=33μM, disrupts serine synthesis, selectively targets high-serine cancers.Formule :C14H12N2O4S2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :336.392-Bromoacetamide
CAS :2-Bromoacetamide (α-Bromoacetamide) is a class of disinfection by-products that exhibit developmental toxicity in animals.Formule :C2H4BrNODegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :137.96CHIKV-IN-2
CAS :CHIKV-IN-2 inhibits DHODH to thwart viruses like CHIKV by depleting pyrimidine, showing strong antiviral action (EC90=270 nM) and liver stability.Formule :C23H26N2O2Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :362.46Ref: TM-T9394
1mg58,00€5mg128,00€10mg187,00€25mg334,00€50mg504,00€100mg730,00€200mg938,00€1mL*10mM (DMSO)140,00€MF-438
CAS :MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).Formule :C19H18F3N5OSDegré de pureté :98.98% - 99.50%Couleur et forme :SolidMasse moléculaire :421.44Ref: TM-T16068
1mg97,00€2mg144,00€5mg215,00€10mg328,00€25mg557,00€50mg797,00€100mg1.103,00€500mg2.205,00€1mL*10mM (DMSO)235,00€Mutant IDH1-IN-1
CAS :Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.Formule :C30H31FN4O2Degré de pureté :100% - 99.49%Couleur et forme :SolidMasse moléculaire :498.59Ref: TM-T2043
1mg46,00€2mg62,00€5mg92,00€10mg140,00€25mg261,00€50mg374,00€100mg547,00€200mg740,00€1mL*10mM (DMSO)97,00€CVT-10216
CAS :CVT-10216 inhibits ALDH2 (IC50: 29 nM) and ALDH-1 (IC50: 1.3 μM), reducing alcohol intake and anxiety in rats.Formule :C24H19NO7SDegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :465.484-Hydroxyderricin
CAS :4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50: 3.43 μM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine β-Formule :C21H22O4Degré de pureté :97.02% - 98%Couleur et forme :SolidMasse moléculaire :338.4SW209049
CAS :SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.Formule :C25H18N2O4SDegré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :442.49Ref: TM-T9859
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg475,00€100mg638,00€200mg845,00€1mL*10mM (DMSO)170,00€BI-3231
CAS :BI-3231 is a hydroxysteroid 17ß-dehydrogenase 13 HSD17B13 inhibitor that inhibits hHSD17B13 .BI-3231 can be used to study cirrhosis.Formule :C16H14F2N4O3SDegré de pureté :98.2%Couleur et forme :SolidMasse moléculaire :380.37Ref: TM-T73446
1mg88,00€5mg188,00€10mg281,00€25mg492,00€50mg688,00€100mg938,00€200mg1.293,00€1mL*10mM (DMSO)208,00€DSM265
CAS :DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity.DSM265 can be used for the treatment of malaria infections.Formule :C14H12F7N5SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :415.33Perfluorooctanoic acid
CAS :Perfluorooctanoic acid (PFOA) (PFOA) is a persistent and widespread industry-made chemical.Formule :C8HF15O2Degré de pureté :99.70%Couleur et forme :White To Off-White Powder OthersolidMasse moléculaire :414.07Ref: TM-T9333
5mg55,00€10mg82,00€25mg126,00€50mg182,00€100mg273,00€200mg409,00€500mg677,00€1mL*10mM (DMSO)81,00€MK-8245
CAS :MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.Formule :C17H16BrFN6O4Degré de pureté :97.58% - 99%Couleur et forme :SolidMasse moléculaire :467.25Ref: TM-T2650
1mg39,00€5mg96,00€10mg153,00€25mg273,00€50mg465,00€100mg648,00€200mg900,00€1mL*10mM (DMSO)97,00€KM04416
CAS :KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.Formule :C12H11NO3SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :249.29Sibiricose A5
CAS :Sibiricose A5: LDH inhibitor with antidepressant, antioxidant effects; shields PC12 cells from P. tenuifolia damage.Formule :C22H30O14Degré de pureté :99.39% - ≥95%Couleur et forme :SolidMasse moléculaire :518.47Tenuifoliside C
CAS :Tenuifoliside C, from Polygala tenuifolia, inhibits lactate dehydrogenase and CYP2E1-mediated chlorzoxazone hydroxylation.Formule :C35H44O19Degré de pureté :97.64% - 99.91%Couleur et forme :SolidMasse moléculaire :768.71Ref: TM-T2S2211
1mg93,00€2mg126,00€5mg187,00€10mg324,00€25mg512,00€50mg658,00€100mg929,00€1mL*10mM (DMSO)304,00€G6PDi-1
CAS :G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.Formule :C14H12N4OSDegré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :284.34IMPDH2-IN-2
CAS :IMPDH2-IN-2 is an IMPDH inhibitor with antimicrobial activity and potential anti-tuberculosis activity for the study of inflammation and immune dysfunction.Formule :C21H15Cl2N3O3Degré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :428.27(R)-GNE-140
CAS :(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.Formule :C25H23ClN2O3S2Degré de pureté :95.46% - 98.90%Couleur et forme :SolidMasse moléculaire :499.04CPS-11
CAS :CPS-11, a Thalidomide analogue, shows potent, broad antitumor activity, especially in multiple myeloma cells.Formule :C14H12N2O5Degré de pureté :99.30% - 99.55%Couleur et forme :SolidMasse moléculaire :288.26Antiproliferative agent-13
CAS :Antiproliferative agent-13 is a compound with antiproliferative activity.Formule :C20H18N2O6Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :382.37Ref: TM-T9974
2mg35,00€5mg52,00€10mg90,00€25mg170,00€50mg259,00€100mg383,00€200mg545,00€1mL*10mM (DMSO)58,00€Ethionamide
CAS :Ethionamide: antibacterial used to treat TB; may block mycolic acid synthesis, disrupting bacterial walls. Its effect varies with concentration and organism.Formule :C8H10N2SDegré de pureté :99.45%Couleur et forme :Yellow Crystals From Ethanol Odor (Ntp 1992)Masse moléculaire :166.24FX-11
CAS :FX-11: potent LDHA inhibitor (Ki 8 μM), activates PKM2, reduces ATP, induces oxidative stress/ROS, cell death, shows antitumor effects.Formule :C22H22O4Degré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :350.41AGI-5198
CAS :AGI-5198 (IDH-C35) is a highly effective and specific inhibitor of IDH1 R132H/R132C mutants (IC50: 0.07/0.16 μM).Formule :C27H31FN4O2Degré de pureté :97.3% - 99.23%Couleur et forme :SolidMasse moléculaire :462.56hDHODH-IN-4
CAS :hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.Formule :C21H24N4O2Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :364.44CP-642931
CAS :CP-642931 (Sorbitol dehydrogenase-IN-1) is a sorbitol dehydrogenase inhibitor used in the study of diabetes mellitus and cardiovascular disease.Formule :C17H25N7ODegré de pureté :100% - 99.94%Couleur et forme :SolidMasse moléculaire :343.43IDH2R140Q-IN-2
CAS :IDH2R140Q-IN-2 is an IDH2R140Q inhibitor indicated for the study of acute myeloid leukaemia (AML).Formule :C21H18F6N6ODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :484.4AG-636
CAS :AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.Formule :C21H17N3O2Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :343.38Epostane
CAS :Epostane is a 3β-hydroxysteroid dehydrogenase inhibitor that blocks the biosynthesis of progesterone and pregnenolone.Cost-effective and quality-assured.Formule :C22H31NO3Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :357.4917β-HSD10-IN-1
CAS :17β-HSD10-IN-1 is a 17β-hydroxysteroid dehydrogenase type 10 inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.Formule :C16H13ClN4O3SDegré de pureté :98.47%Couleur et forme :SoildMasse moléculaire :376.82DHODH-IN-13
CAS :DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.Formule :C10H6F3N3O3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :273.17BI-187004
CAS :BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.Formule :C21H18N4ODegré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :342.39Laflunimus
CAS :Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.Formule :C15H13F3N2O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :310.27BMS-823778
CAS :BMS-823778 is a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) for the study of type 2 diabetes.Formule :C18H18ClN3ODegré de pureté :99.38% - 99.39%Couleur et forme :SolidMasse moléculaire :327.81KPLH1130
CAS :KPLH1130, a PDK inhibitor, boosts glucose tolerance and reduces inflammation in high-fat diet mice.Formule :C15H13N3O3Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :283.28Ref: TM-T11765
1mg84,00€5mg216,00€10mg350,00€25mg590,00€50mg840,00€100mg1.130,00€500mg2.308,00€1mL*10mM (DMSO)188,00€ML390
CAS :ML390 exerts its potent differentiation effect on multiple leukemia models.Formule :C21H21F3N2O3Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :406.44-Isopropoxybenzaldehyde
CAS :ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.Formule :C10H12O2Degré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :164.2
