Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
Produits appartenant à la catégorie "Déshydrogénase"
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AG-120 (racemic)
CAS :AG-120 (racemic) is an oral IDH1 inhibitor with potential anti-cancer effects.Formule :C28H22ClF3N6O3Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :582.96ALDH1A2-IN-1
CAS :ALDH1A2-IN-1 is a reversible active-site-directed ALDH1A2 inhibitor preventing spermatogenesis, useful in male contraceptive research.Formule :C21H26N4O4SDegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :430.52Ref: TM-T39675
1mg52,00€5mg116,00€10mg182,00€25mg364,00€50mg567,00€100mg823,00€200mg1.111,00€1mL*10mM (DMSO)133,00€Daidzin
CAS :Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.Formule :C21H20O9Degré de pureté :98.20% - 99.43%Couleur et forme :White PowderMasse moléculaire :416.38Imidazole-5-propionic acid
CAS :Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination.Formule :C6H8N2O2Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :140.14BAY-1436032
CAS :BAY-1436032 is a novel, selective and orally available inhibitor of pan-mutant isocitrate dehydrogenase 1 (IDH1).Formule :C26H30F3N3O3Degré de pureté :99.38% - 99.65%Couleur et forme :SolidMasse moléculaire :489.53PKUMDL-WQ-2101
CAS :PKUMDL-WQ-2101 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase with anti-tumor activity.Formule :C14H11N3O6Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :317.25Nitrofurazone
CAS :Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria.Formule :C6H6N4O4Degré de pureté :99.87%Couleur et forme :Pale Yellow Needles Solution) 6 0 - 6 5 Alkaline Solutions Are Dark Orange (Ntp 1992)Masse moléculaire :198.14Leflunomide
CAS :Leflunomide (HWA486) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.Formule :C12H9F3N2O2Degré de pureté :99.52% - 99.96%Couleur et forme :Off White Crystalline SolidMasse moléculaire :270.21Tiazofurin
CAS :Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.Formule :C9H12N2O5SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :260.27Ref: TM-T40686
1mg150,00€5mg304,00€10mg437,00€25mg677,00€50mg900,00€100mg1.225,00€200mg1.644,00€1mL*10mM (DMSO)284,00€11β-HSD1-IN-1
CAS :11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.Formule :C18H14ClF4N3ODegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :399.77Ref: TM-T10160
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg472,00€100mg645,00€200mg868,00€1mL*10mM (DMSO)170,00€DHODH-IN-14
CAS :DHODH-IN-14 is an analog of hydroxyfuran pyrimidine A771726.Formule :C15H7F4N3O3Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :353.23Ref: TM-T11023
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mgÀ demander1mL*10mM (DMSO)264,00€LDH-IN-1
CAS :LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).Formule :C30H26N4O4S2Degré de pureté :99.60%Couleur et forme :SolidMasse moléculaire :570.68Ref: TM-T11829
1mg202,00€2mg283,00€5mg432,00€10mg638,00€25mg1.008,00€50mg1.359,00€100mg1.825,00€1mL*10mM (DMSO)545,00€KS100
CAS :KS100 inhibits ALDH1A1, ALDH2, ALDH3A1, boosts ROS, triggers apoptosis, and has anti-cancer properties.Formule :C17H14Br3N3O2SDegré de pureté :97.05%Couleur et forme :SolidMasse moléculaire :564.09CM10
CAS :CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.Formule :C20H23N3ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :321.42Nifurtimox
CAS :Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T.Formule :C10H13N3O5SDegré de pureté :99.87% - 99.92%Couleur et forme :SolidMasse moléculaire :287.29Ref: TM-T5325
2mg42,00€5mg64,00€10mg101,00€25mg192,00€50mg338,00€100mg485,00€200mg655,00€1mL*10mM (DMSO)70,00€11β-HSD1-IN-12
CAS :11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndromeFormule :C19H27ClN2O3SDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :398.95SCD1 inhibitor-4
CAS :SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.Formule :C17H16F3N5ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :363.34Ref: TM-T10525
2mg46,00€5mg64,00€10mg104,00€25mg202,00€50mg325,00€100mg469,00€200mg650,00€1mL*10mM (DMSO)74,00€NCT-501
CAS :NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.Formule :C21H32N6O3Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :416.52IDH889
CAS :IDH889: Brain-penetrant, mutant-specific IDH1 inhibitor; selective for IDH1 R132* mutations. IC50: 0.02μM (R132H), 0.072μM (R132C), 1.38μM (wild-type).Formule :C23H25FN6O2Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :436.48DG 381B
CAS :DG 381B (11-Deoxyglycyrrhetinic acid) has anti-inflammatory and potential anticancer activity, inhibiting tumor formation in nude mouse gastric cancer cells.Formule :C30H48O3Couleur et forme :SoildMasse moléculaire :456.7BI-135585
CAS :BI-135585 is an orally active, selective and potent inhibitor of human 11β-hydroxysteroid dehydrogenase-1 (HSD1) for the study of type 2 diabetes.Formule :C28H32N2O4Degré de pureté :99.45% - 99.66%Couleur et forme :SolidMasse moléculaire :460.57BI-4924
CAS :BI-4924 is a PHGDH inhibitor that disrupts serine biosynthesis by intracellular trapping and can be used to study metabolic disorders.Formule :C21H20Cl2N2O6SDegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :499.36Succinyl phosphonate trisodium salt
CAS :Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)Formule :C4H4Na3O6PDegré de pureté :≥95% - ≥98%Couleur et forme :SolidMasse moléculaire :248.01Isomalt
CAS :Isomalt (Palatinitol) is a mixture of 1,6-mannitol glucopyranoside and 1,6-sorbitol glucopyranosideFormule :C12H24O11Degré de pureté :99.74%Couleur et forme :White Crystalline PowderMasse moléculaire :344.31Olutasidenib
CAS :Olutasidenib (FT-2102), an IDH1 inhibitor (IC50: 21.2/114 nM), is studied for treating AML/MDS and can cross the blood-brain barrier.Formule :C18H15ClN4O2Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :354.79Ref: TM-T16384
1mg62,00€5mg169,00€10mg264,00€25mg487,00€50mg710,00€100mg998,00€200mg1.320,00€1mL*10mM (DMSO)178,00€IGP-1
CAS :iGP-1 is a cell-permeable mitochondrial sn-Glycerol 3-phosphate dehydrogenase (mGPDH) inhibitor.Formule :C17H15N3O3Degré de pureté :99.14% - 99.52%Couleur et forme :SolidMasse moléculaire :309.32Manitimus
CAS :Manitimus is a potent immunosuppressive drug, and is an inhibitor of dehydroorotate dehydrogenase,.Formule :C15H11F3N2O2Degré de pureté :99.75% - 99.75%Couleur et forme :SolidMasse moléculaire :308.26ALDH2 modulator 1
CAS :ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.Formule :C18H18ClFN2O3Degré de pureté :98.07%Couleur et forme :SoildMasse moléculaire :364.8Ref: TM-T67832
1mg64,00€5mg167,00€10mg264,00€25mg435,00€50mg610,00€100mg815,00€200mg1.103,00€1mL*10mM (DMSO)177,00€Ammonium Glycyrrhizinate
CAS :Ammonium Glycyrrhizinate (Glycyram) inhibits the cytopathology and growth of several unrelated DNA/RNA viruses.Formule :C42H62O16·NH3Degré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :839.96Ivosidenib
CAS :Ivosidenib (AG-120) is an oral IDH1 inhibitor targeting mutated IDH1 to reduce 2-hydroxyglutarate and hinder tumor growth.Formule :C28H22ClF3N6O3Degré de pureté :100% - 99.7%Couleur et forme :SolidMasse moléculaire :582.96BVT 2733
CAS :BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.Formule :C17H21ClN4O3S2Degré de pureté :98% - 99.64%Couleur et forme :SolidMasse moléculaire :428.96DHODH-IN-23
CAS :DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.Formule :C24H21ClFNO4Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :441.88DSM502
CAS :DSM502 DSM502 is a dihydroorotic acid dehydrogenase (DHODH) inhibitor with antimalarial activity that inhibits Plasmodium DHODH and can be used as a lead for antimalarial compounds.Formule :C16H16F3N3ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :323.31Ref: TM-T40087
1mg130,00€2mg187,00€5mg311,00€10mg502,00€25mg1.026,00€50mg1.501,00€100mg2.052,00€1mL*10mM (DMSO)344,00€AZD7545
CAS :AZD7545 is a potent PDHK inhibitor.Formule :C19H18ClF3N2O5SDegré de pureté :98.69% - 99.13%Couleur et forme :SolidMasse moléculaire :478.87Enasidenib
CAS :Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potentialFormule :C19H17F6N7ODegré de pureté :100% - 99.8%Couleur et forme :SolidMasse moléculaire :473.38Ref: TM-T2346
5mg47,00€10mg70,00€25mg93,00€50mg111,00€100mg144,00€200mg207,00€500mg350,00€1mL*10mM (DMSO)50,00€Tenovin-6
CAS :Tenovin-6 is a p53 transcriptional activity agonist.Formule :C25H34N4O2SDegré de pureté :100% - 97.71%Couleur et forme :SolidMasse moléculaire :454.63Ref: TM-T1818
1mg43,00€2mg56,00€5mg77,00€10mg87,00€25mg157,00€50mg230,00€100mg393,00€500mg930,00€1mL*10mM (DMSO)79,00€DHODH-IN-4
CAS :DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.Formule :C17H12Cl2N2O2Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :347.2Ref: TM-T11027
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mg2.147,00€1mL*10mM (DMSO)261,00€Taraxerone
CAS :Taraxerone exhibits allelopathic, antifungal properties; it stabilizes catalase, SOD, and counters ethanol-induced glutathione reduction.Formule :C30H48ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :424.7Adrenosterone
CAS :Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.Formule :C19H24O3Degré de pureté :97.04% - 98.13%Couleur et forme :SolidMasse moléculaire :300.39DHODH-IN-16
CAS :DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).Formule :C24H25FN4O3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :436.48Enasidenib mesylate
CAS :Enasidenib mesylate (AG-221 mesylate) is a IDH2 inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia.Formule :C20H21F6N7O4SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :569.4818β-Glycyrrhetinic acid
CAS :18β-Glycyrrhetinic acid (Enoxolone) is the major bioactive component of Glycyrrhizae Radix and possesses anti-inflammatory and antiproliferative properties.Formule :C30H46O4Degré de pureté :99.03% - 99.64%Couleur et forme :SolidMasse moléculaire :470.68Tenuifoliside B
CAS :Tenuifoliside B is a natural product from the roots of Polygala tenuifolia.And is a target lactate dehydrogenase inhibitor.Formule :C30H36O17Degré de pureté :98% - 99.17%Couleur et forme :SolidMasse moléculaire :668.6Ref: TM-T5702
1mg85,00€5mg163,00€10mg269,00€25mg432,00€50mg562,00€100mg787,00€200mg1.035,00€1mL*10mM (DMSO)225,00€Iristectorin A
CAS :Iristectorin A is an isoflavone compound derived from Iris tectorum Maxim, a lactate dehydrogenase inhibitor used in cancer research.Formule :C23H24O12Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :492.43WIN 18446
CAS :inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)Formule :C12H20Cl4N2O2Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :366.11TC HSD 21
CAS :TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).Formule :C17H12BrNO3S2Degré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :422.32Ref: TM-T13100
1mg74,00€5mg145,00€10mg210,00€25mg340,00€50mg492,00€100mg662,00€200mg892,00€1mL*10mM (DMSO)135,00€IDH1 Inhibitor 2
CAS :IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).Formule :C26H22N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.48Merimepodib
CAS :Merimepodib (VX-497) is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH).Formule :C23H24N4O6Degré de pureté :98.77% - 99.31%Couleur et forme :SolidMasse moléculaire :452.46ALDH1A1-IN-2
CAS :ALDH1A1-IN-2 is an aldehyde dehydrogenase 1a1 inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesityFormule :C25H23ClN4O3SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :494.99BI-4916
CAS :BI-4916 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor that inhibits SSP and reduces cancer cell migration.Formule :C23H24Cl2N2O6SDegré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :527.42
