Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
Produits appartenant à la catégorie "Déshydrogénase"
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Galloflavin
CAS :Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.Formule :C12H6O8Degré de pureté :96.24% - 97.47%Couleur et forme :SolidMasse moléculaire :278.17Sodium dichloroacetate
CAS :Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.Formule :C2HCl2NaO2Degré de pureté :99.32% - 99.87%Couleur et forme :White PowderMasse moléculaire :150.92LDHA-IN-4
CAS :LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA expressed in E.coli BL21 (DE3) by SPR analysis with an active value of 93 nM.Formule :C25H27N3O6SDegré de pureté :98.17% - 99.68%Couleur et forme :SolidMasse moléculaire :497.56A939572
CAS :A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.Formule :C20H22ClN3O3Degré de pureté :100% - ≥95%Couleur et forme :SolidMasse moléculaire :387.86Ref: TM-T4515
1mg47,00€2mg63,00€5mg95,00€10mg115,00€25mg230,00€50mg454,00€100mg648,00€500mg1.320,00€1mL*10mM (DMSO)81,00€BAY-2402234
CAS :BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.Formule :C21H18ClF5N4O4Degré de pureté :98.90%Couleur et forme :SolidMasse moléculaire :520.84Ref: TM-T14501
1mg173,00€2mg246,00€5mg368,00€10mg567,00€25mg905,00€50mg1.225,00€100mg1.644,00€1mL*10mM (DMSO)424,00€RV01
CAS :RV01, a resveratrol-like quinoline, inhibits DNA damage, ALDH2 expression, and has antioxidant and anti-inflammatory properties.Formule :C17H13NO2Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :263.29Ref: TM-T12781
1mg62,00€5mg135,00€10mg207,00€25mg353,00€50mg509,00€100mg672,00€200mg910,00€1mL*10mM (DMSO)149,00€DHODH-IN-11
CAS :DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.Formule :C15H11N3O2Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :265.27Benzyl alcohol
CAS :Benzyl alcohol (Benzenemethanol), a colorless liquid, is an aromatic alcohol with a mild pleasant aromatic odor.Formule :C7H8ODegré de pureté :97.61%Couleur et forme :Liquid LiquidMasse moléculaire :108.14hDHODH-IN-3
CAS :hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.Formule :C18H19BrN4O2Degré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :403.27Ref: TM-T11025
1mg64,00€2mg93,00€5mg140,00€10mg215,00€25mg354,00€50mg500,00€100mg658,00€500mgÀ demander1mL*10mM (DMSO)150,00€Ribavirin
CAS :Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.Formule :C8H12N4O5Degré de pureté :98.53% - 99.83%Couleur et forme :Less Solid Colourless SolidMasse moléculaire :244.2Isovaleramide
CAS :Isovaleramide (3-Methylbutanamide) is an anticonvulsant molecule isolated from Valeriana pavonii, which can inhibit the liver alcohol dehydrogenases.Formule :C5H11NODegré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :101.15BRD9185
CAS :BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.Formule :C23H21F6N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :485.42PfDHODH-IN-2
CAS :PfDHODH-IN-2: powerful antimalarial, blocks PfDHODH (IC50: 1.11 μM), for malaria research.Formule :C13H12ClNO3SDegré de pureté :98.90%Couleur et forme :SolidMasse moléculaire :297.76Ref: TM-T8767
1mg48,00€5mg97,00€10mg145,00€25mg259,00€50mg383,00€100mg545,00€200mg740,00€1mL*10mM (DMSO)105,00€Olorofim
CAS :Olorofim(F-901318)is a new selective antifungal compound that inhibits Aspergillus fumigatus DHODH (IC50: 44 nM). Cost-effective and quality-assured.Formule :C28H27FN6O2Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :498.55Brequinar sodium
CAS :Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis.Formule :C23H14F2NNaO2Degré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :397.36Ref: TM-T8332
1mg37,00€5mg94,00€10mg138,00€25mg246,00€50mg320,00€100mg449,00€200mg633,00€1mL*10mM (DMSO)99,00€11β-HSD1-IN-11
CAS :11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13Formule :C15H11F3O3SDegré de pureté :99.42%Couleur et forme :SoildMasse moléculaire :328.31Ref: TM-T60149
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€500mg2.157,00€1mL*10mM (DMSO)251,00€NCT-503
CAS :NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.Formule :C20H23F3N4SDegré de pureté :99.31% - 99.84%Couleur et forme :SolidMasse moléculaire :408.48Ref: TM-T4213
2mg42,00€5mg63,00€10mg90,00€25mg187,00€50mg339,00€100mg528,00€200mg733,00€1mL*10mM (DMSO)69,00€Tryptamine
CAS :Tryptamine: a monoamine alkaloid, similar to tryptophan, with an indole ring, acts as a neurotransmitter in mammalian brains.Formule :C10H12N2Degré de pureté :99.16%Couleur et forme :Solid PowderMasse moléculaire :160.22Metapramine
CAS :Metapramine, a tricyclic antidepressant, blocks norepinephrine reuptake and is a low-affinity NMDA antagonist.Formule :C16H18N2Degré de pureté :98.94% - 99.65%Couleur et forme :SolidMasse moléculaire :238.33Etamicastat hydrochloride
CAS :Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.Formule :C14H16ClF2N3OSDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :347.81Ref: TM-T11238L
1mg127,00€5mg305,00€10mg455,00€25mg742,00€50mg1.017,00€100mg1.454,00€1mL*10mM (DMSO)335,00€Qc1
CAS :Qc1 is an inhibitor of threonine dehydrogenase (TDH) inhibitor and can be used in studies about metabolic diseases.Formule :C23H16F3N3O2SDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :455.45Chloramphenicol succinate
CAS :Chloramphenicol succinate is a bacteriostatic antibiotic. CPSA is a competitive substrate and inhibitor of succinate dehydrogenase (SDH),can be oxidized by.Formule :C15H16Cl2N2O8Degré de pureté :95.32%Couleur et forme :Physical Description White Powder (Ntp 1992)Masse moléculaire :423.2RS 61443
CAS :RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)Formule :C23H31NO7Degré de pureté :99.37% - 99.91%Couleur et forme :SolidMasse moléculaire :433.5HSD-016
CAS :HSD-016: Oral 11β-HSD1 inhibitor, active in humans, mice, rats (IC50: 11, 1, 8 nM), potential for type 2 diabetes research.Formule :C21H21F7N2O3SDegré de pureté :98.77% - 99.21%Couleur et forme :SolidMasse moléculaire :514.46Ref: TM-T63569
1mg88,00€5mg296,00€10mg464,00€25mg938,00€50mg1.568,00€100mg2.490,00€1mL*10mM (DMSO)328,00€DSM421
CAS :DSM421 (DSM-421) is a dihydrodehydrogenase inhibitor (DHODH) that is in preclinical development as a potential treatment option for malaria and has shownFormule :C14H11F5N6Degré de pureté :99.82% - 99.93%Couleur et forme :SolidMasse moléculaire :358.27Ref: TM-T27214
1mg116,00€5mg273,00€10mg373,00€25mg563,00€50mg758,00€100mg998,00€200mg1.320,00€1mL*10mM (DMSO)319,00€11β-HSD1 inibitor 17
CAS :11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).Formule :C22H20F3N3O2SDegré de pureté :99.24% - 99.56%Couleur et forme :SoildMasse moléculaire :447.47R162
CAS :R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.Formule :C17H12O3Degré de pureté :96.21% - 97.68%Couleur et forme :SolidMasse moléculaire :264.28Ref: TM-T4173
1mg40,00€2mg51,00€5mg85,00€10mg135,00€25mg283,00€50mg452,00€100mg645,00€500mg1.311,00€1mL*10mM (DMSO)93,00€IMB-XMA0038
CAS :IMB-XMA0038 is a Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase inhibitor with antimicrobial activity for use in tuberculosis research.Formule :C11H10N4O6Degré de pureté :98.99% - 99.92%Couleur et forme :SolidMasse moléculaire :294.22(E/Z)-Teriflunomide
CAS :(E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.Formule :C12H9F3N2O2Degré de pureté :99.49% - 99.76%Couleur et forme :White SolidMasse moléculaire :270.21Diammonium Glycyrrhizinate
CAS :Diammonium Glycyrrhizinate, a licorice-derived anti-inflammatory, metabolizes to glycyrrhetinic acid, affecting corticosteroid metabolism & blood pressure.Formule :C42H62O16·2H3NDegré de pureté :90% - 99.71%Couleur et forme :SolidMasse moléculaire :857Fomepizole
CAS :Fomepizole (4-Methylpyrazole), a competitive inhibitor of alcohol dehydrogenase, is used as an antidote in methanol or ethylene glycol poisoning.Formule :C4H6N2Degré de pureté :98.1% - 99.94%Couleur et forme :Yellow <13°C Solid >13°C LiquidMasse moléculaire :82.1Mycophenolic acid
CAS :Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.Formule :C17H20O6Degré de pureté :98.79% - 99.77%Couleur et forme :SolidMasse moléculaire :320.342-Pyridinecarbohydrazide
CAS :2-Pyridinecarbohydrazide (2-Picolinyl hydrazide) is an effective inhibitor of Catalase-peroxidase-NAPDH.Formule :C6H7N3ODegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :137.14NCT-502
CAS :NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor,Formule :C18H20F3N5SDegré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :395.45Ref: TM-T16277
2mg39,00€5mg57,00€10mg87,00€25mg159,00€50mg240,00€100mg415,00€500mg933,00€1mL*10mM (DMSO)63,00€Nitrophenide
CAS :Nitrophenide, a 3,3'-Dinitrodiphenyl disulfide, blocks M1PDH in the mannitol cycle, serving as an anticoccidial.Formule :C12H8N2O4S2Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :308.33SKI2852
CAS :SKI2852 is an 11β-HSD1 inhibitor that improves metabolic syndrome in diabetic mouse models.Formule :C27H34FN5O4SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :543.65XEN723
CAS :XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).Formule :C21H20FN5O2SDegré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :425.48Ref: TM-T13356
1mg55,00€5mg116,00€10mg178,00€25mg304,00€50mg437,00€100mg615,00€200mg830,00€1mL*10mM (DMSO)139,00€DHODH-IN-17
CAS :DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM.Formule :C12H9ClN2O2Degré de pureté :100% - 100%Couleur et forme :SolidMasse moléculaire :248.67Ref: TM-T60364
5mg70,00€10mg103,00€25mg202,00€50mg303,00€100mg449,00€500mg938,00€1mL*10mM (DMSO)74,00€ML-148
CAS :ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM).Formule :C20H21N3ODegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :319.4Ref: TM-T38163
1mg60,00€5mg180,00€10mg283,00€25mg510,00€50mg737,00€100mg1.026,00€500mg2.062,00€1mL*10mM (DMSO)188,00€hDHODH-IN-7
CAS :hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.Formule :C21H23FN4ODegré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :366.43Ref: TM-T11031
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mg2.147,00€1mL*10mM (DMSO)266,00€DHODH-IN-15
CAS :DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.Formule :C15H11N3O3Degré de pureté :97.26%Couleur et forme :SolidMasse moléculaire :281.27Ref: TM-T11024
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€200mg1.454,00€1mL*10mM (DMSO)239,00€4-Hydroxynonenal
CAS :4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).Formule :C9H16O2Degré de pureté :95.12%Couleur et forme :Clear Colorless LiquidMasse moléculaire :156.22AGI-6780
CAS :AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.Formule :C21H18F3N3O3S2Degré de pureté :97.47% - 98.19%Couleur et forme :SolidMasse moléculaire :481.51Ref: TM-T1809
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg220,00€50mg393,00€100mg587,00€500mg1.264,00€1mL*10mM (DMSO)85,00€BVT-14225
CAS :BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).Formule :C16H20ClN3O3S2Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :401.93Ref: TM-T3542
1mg47,00€2mg59,00€5mg96,00€10mg142,00€25mg254,00€50mg411,00€100mg610,00€1mL*10mM (DMSO)105,00€Etamicastat
CAS :Etamicastat can be used in the research of cardiovascular diseases.Formule :C14H15F2N3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :311.35hDHODH-IN-5
CAS :hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).Formule :C21H21F3N2O2Degré de pureté :98.70%Couleur et forme :SolidMasse moléculaire :390.4Ref: TM-T11029
1mg85,00€5mg166,00€10mg234,00€25mg376,00€50mg560,00€100mg797,00€1mL*10mM (DMSO)175,00€DS-1001b
CAS :DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)Formule :C29H29Cl3FN3O4Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :608.92Ref: TM-T7741
1mg37,00€5mg79,00€10mg119,00€25mg187,00€50mg354,00€100mg528,00€200mg743,00€1mL*10mM (DMSO)97,00€LDHA-IN-3
CAS :LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.Formule :C13H9F3SeDegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :301.17Ref: TM-T39805
1mg55,00€5mg119,00€10mg187,00€25mg393,00€50mg562,00€100mg800,00€200mg1.074,00€1mL*10mM (DMSO)131,00€VER-246608
CAS :VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.Formule :C28H23ClF2N4O4Degré de pureté :98.50%Couleur et forme :SolidMasse moléculaire :552.96Ref: TM-T17224
1mg52,00€2mg74,00€5mg111,00€10mg170,00€25mg329,00€50mg502,00€100mg730,00€1mL*10mM (DMSO)137,00€GSK1940029
CAS :GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.Formule :C18H16Cl2N4O2Degré de pureté :98.72% - 99.48%Couleur et forme :SolidMasse moléculaire :391.25
