Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
Produits appartenant à la catégorie "Déshydrogénase"
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ALDH1A3-IN-2
CAS :ALDH1A3-IN-2 is a potent ALDH1A3 inhibitor with an IC50 of 0.30 μM.ALDH1A3-IN-2 has potential for cancer disease research.Formule :C13H17NODegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :203.28Ketogestin
CAS :Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.Formule :C21H28O3Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :328.45DHODH-IN-1
CAS :DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.Formule :C21H20F3N3O2Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :403.4Ref: TM-T11019
1mg88,00€5mg210,00€10mg338,00€25mg562,00€50mg792,00€100mgÀ demander1mL*10mM (DMSO)47,00€SW033291
CAS :SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.Formule :C21H20N2OS3Degré de pureté :97.26% - 99.02%Couleur et forme :SolidMasse moléculaire :412.59Ref: TM-T2121
1mg40,00€2mg52,00€5mg87,00€10mg119,00€25mg210,00€50mg354,00€100mg512,00€1mL*10mM (DMSO)87,00€Mutant IDH1 inhibitor
CAS :Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).Formule :C25H34N6O3Degré de pureté :98.30%Couleur et forme :SolidMasse moléculaire :466.58Ref: TM-T16161
1mg42,00€5mg90,00€10mg135,00€25mg221,00€50mg324,00€100mg452,00€200mg630,00€1mL*10mM (DMSO)94,00€hDHODH-IN-8
CAS :hDHODH-IN-8: potent hDHODH inhibitor, IC50 = 16 nM, antiproliferative, soluble, may research lymphoma.Formule :C21H15F6N3O4Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :487.354-Diethylaminobenzaldehyde
CAS :4-Diethylaminobenzaldehyde: reversible ALDH1 inhibitor (Ki: 4 nM), potent anti-androgen (IC50: 1.71μM).Formule :C11H15NODegré de pureté :99.60%Couleur et forme :Brown-Black CrystalsMasse moléculaire :177.24IGUANA-1
CAS :IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.Formule :C27H26ClN3O4Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :491.97Tenovin-6 Hydrochloride
CAS :Tenovin-6 HCl: Inhibits SIRT1 (21µM), SIRT2 (10µM), HDAC8; potent p53 activator.Formule :C25H35ClN4O2SDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :491.09Ref: TM-T8480
1mg39,00€2mg51,00€5mg70,00€10mg88,00€25mg140,00€50mg226,00€100mg376,00€1mL*10mM (DMSO)73,00€IDH-305
CAS :IDH-305: Oral, mutation-specific IDH1 inhibitor, 200x selective for R132 mutants; IC50: 27/28/6.14 nM for R132H/C/WT.Formule :C23H22F4N6O2Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :490.45AZD8329
CAS :AZD8329 is an 11β-HSD1 inhibitor that inhibits 11β-HSD2, 17β-HSD1, 17β-HSD3, and can be used to study allergic reactions in humans.Formule :C25H31N3O3Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :421.53Ref: TM-T14383
1mg92,00€5mg188,00€10mg311,00€25mg645,00€50mg947,00€100mg1.644,00€1mL*10mM (DMSO)215,00€6''-O-Acetylglycitin
CAS :6''-O-Acetylglycitin (Glycitin 6''-O-Acetate) is a compound that can be extracted from black soybeans and serves as an LDH inhibitor.Formule :C24H24O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :488.44DHODH-IN-12
CAS :DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.Formule :C10H9N3O2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :203.2Ref: TM-T11021
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg472,00€100mg645,00€200mg869,00€1mL*10mM (DMSO)129,00€NCT-505
CAS :NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 withFormule :C27H28FN5O3SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :521.61Ref: TM-T12196
1mg115,00€5mg235,00€10mg353,00€25mg562,00€50mg758,00€100mg1.017,00€200mg1.359,00€1mL*10mM (DMSO)270,00€Disulfiram
CAS :Disulfiram, a carbamate, deters alcohol use by blocking aldehyde dehydrogenase, causing unpleasant effects when alcohol is consumed.Formule :C10H20N2S4Degré de pureté :98.17% - 99.79%Couleur et forme :White To Off-White Crystalline Powder Unpleasant Taste With Metallic Or Garlic Aftertaste Ph Of A Solution Obtained By Shaking 1 G With 30Masse moléculaire :296.54DHODH-IN-8
CAS :DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).Formule :C17H13ClN2O2Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :312.75Ref: TM-T11030
1mg115,00€2mg172,00€5mg255,00€10mg374,00€25mg562,00€50mg787,00€100mg1.074,00€500mgÀ demander1mL*10mM (DMSO)249,00€PfDHODH-IN-1
CAS :PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.Formule :C14H11F3N2O2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :296.24Ref: TM-T12438
1mg50,00€5mg106,00€10mg160,00€25mg311,00€50mg472,00€100mg695,00€200mg938,00€1mL*10mM (DMSO)97,00€Methylmalonic acid
CAS :Methylmalonic acid (Isosuccinic acid) is a dicarboxylic acid that can be derived from methylmalonyl-coenzyme A.Formule :C4H6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :118.09(Rac)-BMS-816336
(Rac)-BMS-816336 is a racemic 11β-HSD1 inhibitor; IC50: 10 nM (human), 68 nM (mouse), metabolically stable.Formule :C21H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :341.443-Hydroxybenzaldehyde
CAS :3-Hydroxybenzaldehyde is a compound useful in organic synthesis.Formule :C7H6O2Degré de pureté :99.60%Couleur et forme :DrypowderMasse moléculaire :122.12AGI-14100
CAS :AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.Formule :C29H22ClF4N5O3Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :599.96GSK2837808A
CAS :GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).Formule :C31H25F2N5O7SDegré de pureté :99.78% - 99.78%Couleur et forme :SolidMasse moléculaire :649.62Ref: TM-T15435
1mg48,00€5mg111,00€10mg170,00€25mg329,00€50mg455,00€100mg645,00€1mL*10mM (DMSO)168,00€Kakkalide
CAS :Kakkalide is a potent lactate dehydrogenase (LDH) inhibitor, it has anti-inflammatory effects.Formule :C28H32O15Degré de pureté :100% - 99.1%Couleur et forme :SolidMasse moléculaire :608.54CM037
CAS :CM037 (A-37) is a selective ALDH1A1 (acetaldehyde dehydrogenase 1A1) inhibitor (IC50; 4.6 µM) with antitumor activity and may be used in studies to eliminateFormule :C21H25N3O3S2Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :431.57Citric acid trilithium salt tetrahydrate
CAS :Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy ofFormule :C6H13Li3O11Degré de pureté :≥95%Couleur et forme :White Crystalline PowderMasse moléculaire :281.98Carbenoxolone
CAS :Carbenoxolone (Biogastrone) is an inhibitor of 11β-HSD and gap junction connexin channels.Formule :C34H50O7Degré de pureté :99.75%Couleur et forme :White Crystalline PowderMasse moléculaire :570.76CB29
CAS :CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).Formule :C15H15N3O5SDegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :349.36T-3764518
CAS :T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).Formule :C20H17F6N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.37CAY10566
CAS :CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.Formule :C18H17ClFN5O2Degré de pureté :99.50% - 99.54%Couleur et forme :SolidMasse moléculaire :389.81Ref: TM-T14878
1mg51,00€5mg153,00€10mg227,00€25mg464,00€50mg680,00€100mg938,00€500mg1.872,00€1mL*10mM (DMSO)131,00€6PGD-IN-S3
CAS :6PGD-IN-S3 (6PGD Inhibitor S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD).Formule :C15H10O4Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :254.24hDHODH-IN-1
CAS :hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.Formule :C17H14N2O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :278.31Ref: TM-T11546
1mg48,00€5mg97,00€10mg156,00€25mg301,00€50mg439,00€100mg610,00€200mg822,00€1mL*10mM (DMSO)105,00€PHGDH-IN-3
CAS :PHGDH-IN-3, an oral PHGDH blocker with 2.8 μM IC50, may help in cancer research.Formule :C24H18FN3O4S2Degré de pureté :97.24% - 98.99%Couleur et forme :SolidMasse moléculaire :495.55Dicoumarol
CAS :Dicoumarol: an anticoagulant from moldy sweet-clover, depletes vitamin K, inhibits clotting enzymes.Formule :C19H12O6Degré de pureté :100% - 99.9%Couleur et forme :White Or Creamy White Crystalline Powder SolidMasse moléculaire :336.3Proguanil hydrochloride
CAS :Proguanil hydrochloride, a biguanide, metabolizes into cycloguanil, an anti-malaria agent that inhibits plasmodium's DNA and protein synthesis.Formule :C11H17Cl2N5Degré de pureté :98.13% - 98.34%Couleur et forme :SolidMasse moléculaire :290.19
