AhR
Le récepteur des hydrocarbures aromatiques (AhR) est un facteur de transcription activé par un ligand qui joue un rôle crucial dans la régulation des réponses biologiques aux contaminants environnementaux, tels que les dioxines. AhR est également impliqué dans le métabolisme des xénobiotiques et la régulation des réponses immunitaires, de la prolifération et de la différenciation cellulaires. La dysrégulation de la signalisation AhR est liée à diverses maladies, y compris le cancer et les troubles auto-immuns. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs d'AhR pour soutenir vos recherches en toxicologie, biologie du cancer et immunologie.
Produits appartenant à la catégorie "AhR"
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39 produits dans cette catégorie.
Skatole
CAS :Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Formule :C9H9NDegré de pureté :99.74%Couleur et forme :Leaves From Petroleum Ether; White-Brown Scales SolidMasse moléculaire :131.17VAF347
CAS :VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects.Formule :C17H11ClF3N3Degré de pureté :98.75% - 99.55%Couleur et forme :SolidMasse moléculaire :349.74Ref: TM-T13276
1mg40,00€2mg51,00€5mg85,00€10mg119,00€25mg210,00€50mg354,00€100mg528,00€500mg1.159,00€1mL*10mM (DMSO)113,00€DiMNF
CAS :Imigliptin (KBP 3853) is a dipeptidyl peptidase-4 inhibitor used in the study of type 2 diabetes.Formule :C21H16O4Degré de pureté :97.60%Couleur et forme :SolidMasse moléculaire :332.35(-)-Perillaldehyde
CAS :(-)-Perillaldehyde shows antibacterial activity.Formule :C10H14ODegré de pureté :90.68% - 97.21%Couleur et forme :Clear Light Yellow LiquidMasse moléculaire :150.22Tapinarof
CAS :Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.Formule :C17H18O2Degré de pureté :100% - 99.84%Couleur et forme :SolidMasse moléculaire :254.32Ref: TM-T4644
1mg40,00€2mg52,00€5mg85,00€10mg124,00€25mg230,00€50mg350,00€100mg522,00€500mg1.130,00€1mL*10mM (DMSO)88,00€Diosmin
CAS :Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls.Formule :C28H32O15Degré de pureté :97.90%Couleur et forme :Greyish-Yellow Or Light Yellow Hygroscopic PowderMasse moléculaire :608.54Mexiletine hydrochloride
CAS :Mexiletine hydrochloride is a lidocaine-like antiarrhythmic (Class IB) and anesthetic, stabilizing heartbeats by inhibiting sodium in cardiac cells.Formule :C11H18ClNODegré de pureté :99.88%Couleur et forme :White To Off-White SolidMasse moléculaire :215.72BAY-218
CAS :Bindarit (AF2838) is an aryl hydrocarbon receptor (AHR) antagonist.Cost-effective and quality-assured.Formule :C20H17ClFN3O3Degré de pureté :99.46% - 99.85%Couleur et forme :SolidMasse moléculaire :401.82Ref: TM-T5622
1mg40,00€2mg50,00€5mg72,00€10mg115,00€25mg250,00€50mg424,00€100mg630,00€500mg1.320,00€1mL*10mM (DMSO)79,00€Phortress
CAS :Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumorFormule :C20H25Cl2FN4OSDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :459.41FICZ
CAS :FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM).Formule :C19H12N2ODegré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :284.31ITE
CAS :ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.Formule :C14H10N2O3SDegré de pureté :97.91%Couleur et forme :SolidMasse moléculaire :286.31WAY-605471
CAS :WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.Formule :C14H15NO3S2Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :309.4Ref: TM-T9822
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€500mg2.157,00€1mL*10mM (DMSO)249,00€L-Kynurenine
CAS :L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan.Formule :C10H12N2O3Degré de pureté :98.44% - 99.91%Couleur et forme :Light Yellow CrystallineMasse moléculaire :208.21Prochloraz
CAS :Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.Formule :C15H16Cl3N3O2Degré de pureté :99.4%Couleur et forme :Colorless SolidMasse moléculaire :376.67KYN-101
CAS :KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.Formule :C22H19FN6Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :386.43Pifithrin-α hydrobromide
CAS :Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formule :C16H18N2OS·HBrDegré de pureté :100% - 98.54%Couleur et forme :SolidMasse moléculaire :367.3GNF351
CAS :GNF351: Full AHR antagonist, inhibits DRE-dependent/independent activity, low toxicity, binds AHR (IC50: 62 nM).Formule :C24H25N7Degré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :411.5Ref: TM-T15410
1mg44,00€5mg94,00€10mg144,00€25mg283,00€50mg520,00€100mg700,00€200mg945,00€1mL*10mM (DMSO)105,00€PDM2
CAS :PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.Formule :C14H9Cl3Degré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :283.58AHR Inhibitor I-103
CAS :AHR Inhibitor I-103 is an aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity used in the study of breast cancer and acute myeloid leukemia.Formule :C21H17FN6Degré de pureté :98.64%Couleur et forme :SoildMasse moléculaire :372.4StemRegenin 1
CAS :StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.Formule :C24H23N5OSDegré de pureté :98% - 99.88%Couleur et forme :SolidMasse moléculaire :429.54MeBIO
CAS :MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.Formule :C17H12BrN3O2Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :370.2Ref: TM-T21966
1mg39,00€5mg74,00€10mg117,00€25mg220,00€50mg354,00€100mg520,00€500mg1.130,00€1mL*10mM (DMSO)86,00€Indole-3-pyruvic acid
CAS :Indole-3-pyruvic acid is a precursor for the plant growth hormone indole-3-acetic acid.Formule :C11H9NO3Degré de pureté :98.89% - 99.21%Couleur et forme :Off White CrystalsMasse moléculaire :203.19PDM11
CAS :PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR)Formule :C16H15ClO2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :274.74Ref: TM-T5541
1mg49,00€5mg97,00€10mg142,00€25mg226,00€50mg335,00€100mg480,00€200mg662,00€1mL*10mM (DMSO)94,00€5-fluoro 203
CAS :5-fluoro 203 (NSC-703786) is a cytotoxic molecule leading to cell death by forming DNA adducts.Formule :C14H11FN2SDegré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :258.31Ref: TM-T21704
2mg40,00€5mg62,00€10mg96,00€25mg170,00€50mg259,00€100mg374,00€200mg535,00€1mL*10mM (DMSO)59,00€Potassium 1H-indol-3-yl sulfate
CAS :Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR).Formule :C8H6KNO4SDegré de pureté :100% - 99.71%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :251.3PD98059
CAS :PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formule :C16H13NO3Degré de pureté :100% - 99.66%Couleur et forme :Yellow SolidMasse moléculaire :267.28Ref: TM-T2623
5mg40,00€10mg52,00€25mg82,00€50mg106,00€100mg177,00€200mg264,00€500mg444,00€1mL*10mM (DMSO)58,00€CAY 10465
CAS :CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).Formule :C15H9Cl2F3Degré de pureté :98.80%Couleur et forme :SolidMasse moléculaire :317.13Ref: TM-T4607
1mg35,00€2mg52,00€5mg77,00€10mg110,00€25mg227,00€50mg430,00€100mg652,00€1mL*10mM (DMSO)86,00€CH-223191
CAS :CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).Formule :C19H19N5ODegré de pureté :99.01% - 99.71%Couleur et forme :SolidMasse moléculaire :333.393',4'-Dimethoxyflavone
CAS :3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.Formule :C17H14O4Degré de pureté :98.05% - 98.05%Couleur et forme :SolidMasse moléculaire :282.29Benzyl butyl phthalate
CAS :Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC.Formule :C19H20O4Degré de pureté :99.02%Couleur et forme :Colourless Liquid Oily LiquidMasse moléculaire :312.36BAY 2416964
CAS :BAY 2416964 is a small molecule inhibitor that selectively targets aromatic receptor (AhR) and is commonly used in tumor research. Cost-effective and quality-assured.Formule :C18H18ClN5O3Degré de pureté :99.15% - 99.88%Couleur et forme :SolidMasse moléculaire :387.82Ref: TM-T10270
1mg48,00€5mg85,00€10mg120,00€25mg235,00€50mg354,00€100mg567,00€500mg1.188,00€1mL*10mM (DMSO)110,00€1,4-Chrysenequinone
CAS :1,4-Chrysenequinone (Chrysene-1,4-dione) is an activator of aryl hydrocarbon receptor (AhR).Formule :C18H10O2Degré de pureté :96.36% - 99.65%Couleur et forme :SolidMasse moléculaire :258.27Carbidopa
CAS :Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM).Formule :C10H14N2O4Degré de pureté :98.01% - ≥98%Couleur et forme :SolidMasse moléculaire :226.23CAY10464
CAS :CAY10464 (AHR antagonist 7) is an AHR antagonist for the study of cancer and metabolic diseases.Formule :C15H12Cl2ODegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :279.16Brevifolincarboxylic acid
CAS :Natural α-glucosidase inhibitor from Polygonum capitatum; blocks AhR with 323.46 μM IC50.Formule :C13H8O8Degré de pureté :99.31% - 99.42%Couleur et forme :SolidMasse moléculaire :292.2Carbidopa monohydrate
CAS :Carbidopa monohydrate (S(-)-Carbidopa) is an inhibitor of DOPA decarboxylase, preventing the conversion of levodopa to dopamine.Formule :C10H16N2O5Degré de pureté :98.11% - 99.29%Couleur et forme :SolidMasse moléculaire :244.24AhR agonist 2
AhR agonist 2 is aryl hydrocarbon receptor (AhR) agonist,oral, inducing rapid nuclear enrichment of the AhR and facilitating skin barrier repair,psoriasis.Formule :C12H7Br2N3Couleur et forme :SolidMasse moléculaire :353.01YL-109
CAS :YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.Formule :C14H11NO2SDegré de pureté :97.33% - ≥95%Couleur et forme :SolidMasse moléculaire :257.31Ref: TM-T1960
2mg35,00€5mg52,00€10mg80,00€25mg120,00€50mg188,00€100mg274,00€200mg406,00€500mg663,00€1mL*10mM (DMSO)52,00€Indole-3-carbinol
CAS :Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinaseFormule :C9H9NODegré de pureté :100% - 97.06%Couleur et forme :SolidMasse moléculaire :147.17
