récepteur 5-HT
Les récepteurs 5-HT, également connus sous le nom de récepteurs de la sérotonine, sont un groupe de récepteurs couplés aux protéines G (GPCR) qui médiatisent les effets de la sérotonine, un neurotransmetteur impliqué dans la régulation de l'humeur, l'anxiété, le sommeil, l'appétit et d'autres processus physiologiques. Ces récepteurs sont divisés en plusieurs sous-types, chacun ayant des fonctions et des propriétés pharmacologiques distinctes. Les modulateurs des récepteurs 5-HT sont largement étudiés pour leurs rôles dans le traitement de la dépression, des troubles anxieux et d'autres affections neuropsychiatriques. Chez CymitQuimica, nous offrons une gamme de modulateurs des récepteurs 5-HT de haute qualité pour soutenir vos recherches en neuropharmacologie, troubles de l'humeur et signalisation GPCR.
Produits appartenant à la catégorie "récepteur 5-HT"
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Pizotifen Malate
CAS :Pizotifen Malate (BC-105 malate), a highly selective 5-HT receptor blocking agent, is a drug based on benzocycloheptane.Formule :C19H21NS·C4H6O5Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :429.53Repinotan
CAS :Repinotan (BAY x 3702 free base) is a 5-HT1A receptor agonist used in acute ischemic stroke studies.Formule :C21H24N2O4SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :400.49Gentisein
CAS :Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7Formule :C13H8O5Degré de pureté :96.74%Couleur et forme :SolidMasse moléculaire :244.2(Rac)-Norcisapride
CAS :Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.Formule :C14H20ClN3O3Degré de pureté :99.13%Couleur et forme :SoildMasse moléculaire :313.78(S)-Amisulpride
CAS :(S)-Amisulpride ((S) Amisulpride) (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist.Formule :C17H27N3O4SDegré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :369.48Ref: TM-T26375
1mg50,00€2mg71,00€5mg114,00€10mg178,00€25mg340,00€50mg538,00€100mg730,00€200mg938,00€1mL*10mM (DMSO)126,00€AAZ-A 154 hydrobromide
CAS :AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.Formule :C14H21BrN2OCouleur et forme :SolidMasse moléculaire :313.23Ondansetron hydrochloride dihydrate
CAS :Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist,which has reported anxiolytic and neuroleptic properties.Formule :C18H19N3O·HCl·2H2ODegré de pureté :99.92%Couleur et forme :White Crystal PowderMasse moléculaire :365.86SB 243213 hydrochloride
CAS :SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).ItFormule :C22H20ClF3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.87Ipsapirone
CAS :Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses.Formule :C19H23N5O3SDegré de pureté :99.01%Couleur et forme :SolidMasse moléculaire :401.485-HT1A modulator 4
CAS :5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.Formule :C9H14N4Couleur et forme :SolidMasse moléculaire :178.234SB-200646A
CAS :SB-200646A: oral 5-HT2B/2C antagonist; higher affinity than 5-HT2A (pKi: 7.5, 6.9 vs 5.2); anxiolytic with in vivo effects.Formule :C15H15ClN4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.76Adatanserin
CAS :Adatanserin (WY 50324) is a mixed 5-HT1A receptor partial agonist and a 5-HT2A and 5-HT2C receptor antagonist.Formule :C21H31N5ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :369.5ST1936
CAS :ST1936 (ST 1936 oxalate) is a 5-HT6 receptor agonist that stimulates cAMP, Ca2+, ERK1/2, and Fyn kinases by fully activating cloned human 5-HT6 receptors.Formule :C13H17ClN2Degré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :236.74Ref: TM-T23396
1mg47,00€5mg117,00€10mg188,00€25mg334,00€50mg497,00€100mg720,00€200mg1.008,00€1mL*10mM (DMSO)130,00€Cyproheptadine hydrochloride
CAS :Cyproheptadine hydrochloride (Periactin hydrochloride) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist.Formule :C21H21N·HClDegré de pureté :99.88% - 99.97%Couleur et forme :SolidMasse moléculaire :323.86Tropanserin
CAS :Tropanserin (MDL 72422) is a 5-hydroxytryptamine receptor antagonist with anxiolytic activity that is used to treat depression and cognitive impairment.Formule :C17H23NO2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :273.37Sarizotan 2HCl
CAS :Sarizotan 2HCl is an hERG channel inhibitor and 5-hydroxytryptamine 5-HT1A receptor agonist with potential antidepressant effects for the study of Parkinsonian movement disorders.Formule :C22H23Cl2FN2ODegré de pureté :98.83%Couleur et forme :SoildMasse moléculaire :421.345-HT2C agonist-3 free base
CAS :5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-Formule :C19H22FNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.38Sulamserod hydrochloride
CAS :Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.Formule :C19H29Cl2N3O5SCouleur et forme :SolidMasse moléculaire :482.42LY 344864
CAS :LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.Formule :C21H22FN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.42γ-Mangostin
CAS :Gamma-Mangostin (Normangostin) has free radical scavenging activity, and antiproliferative and apoptotic activity. Gamma-Mangostin is an antihypertensive agent.Formule :C23H24O6Degré de pureté :98.55% - 99.08%Couleur et forme :SolidMasse moléculaire :396.43WAY 163909
CAS :WAY 163909 is an effective and selective agonist of the 5-HT(2C) receptor (Ki: 10.5±1.1 nM).Formule :C14H18N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :214.315-HT7 agonist 1
CAS :5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM).Formule :C19H20ClN3Degré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :325.84Ref: TM-T10170
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€1mL*10mM (DMSO)255,00€YM-31636 free base
CAS :YM-31636 (free base) is an orally active, potent, and selective agonist of the 5-HT3 receptor with a pKi value of 9.67. This compound induces contraction in isolated guinea pig distal colon and provokes tachycardia in isolated guinea pig right atrium, demonstrating a relative intrinsic activity of about 0.23. YM-31636 (free base) holds potential for research in constipation management.Formule :C14H11N3SCouleur et forme :SolidMasse moléculaire :253.325-HT2 agonist-1 free base
CAS :Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,Formule :C19H22N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.39Thioridazine hydrochloride
CAS :Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Formule :C21H27ClN2S2Degré de pureté :99.55% - 99.55%Couleur et forme :White To Off-White SolidMasse moléculaire :407.0425N-NBOMe hydrochloride
CAS :25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.Formule :C18H23ClN2O5Couleur et forme :SolidMasse moléculaire :382.84Landipirdine
CAS :Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.Formule :C18H19FN2O3SDegré de pureté :97.50% - 99.33%Couleur et forme :SolidMasse moléculaire :362.42Venlafaxine hydrochloride
CAS :Venlafaxine HCl, a cyclohexanol phenethylamine, acts as an SNRI antidepressant.Formule :C17H28ClNO2Degré de pureté :99.86%Couleur et forme :White Crystalline PowderMasse moléculaire :313.863Adatanserin hydrochloride
CAS :Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.Formule :C21H32ClN5ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :405.96Olopatadine hydrochloride
CAS :Olopatadine hydrochloride (ALO4943A) is an antihistamine with mast-cell stabilizing properties used as eye drops in the treatment of ALLERGIC CONJUNCTIVITIS.Formule :C21H23NO3·HClDegré de pureté :99.62% - 99.64%Couleur et forme :White SolidMasse moléculaire :373.87Latrepirdine dihydrochloride
CAS :Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formule :C21H25N3·2HClDegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :392.37SR 57227 hydrochloride
CAS :SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier.Formule :C10H14ClN3·HClDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :248.15Ref: TM-T23394
5mg50,00€10mg74,00€25mg126,00€50mg210,00€100mg313,00€200mg445,00€1mL*10mM (DMSO)49,00€RS 56812 hydrochloride
CAS :5-HT3 partial agonistFormule :C18H22ClN3O2Degré de pureté :97.69%Couleur et forme :SolidMasse moléculaire :347.84N-Desmethyl Pimavanserin
CAS :N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.Formule :C24H32FN3O2Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :413.53Urapidil
CAS :Urapidil (Ebrantil), a sympatholytic antihypertensive drug, acts as a 5-HT1A receptor agonist and as an α1-adrenoceptor antagonist.Formule :C20H29N5O3Degré de pureté :100% - 99.85%Couleur et forme :SolidMasse moléculaire :387.48Gepirone
CAS :Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.Formule :C19H29N5O2Degré de pureté :99.35% - 99.77%Couleur et forme :SolidMasse moléculaire :359.47Pizotifen
CAS :Pizotifen is a serotonin antagonist with mild anticholinergic effects, used in migraine prevention. Not available in the USA.Formule :C19H21NSDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :295.44Ondansetron
CAS :Ondansetron (GR 38032) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.Formule :C18H19N3ODegré de pureté :99.92%Couleur et forme :White To Yellow CrystalsMasse moléculaire :293.364-Hydroxy MPT
CAS :4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Formule :C14H20N2OCouleur et forme :SolidMasse moléculaire :232.32Olanzapine
CAS :Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.Formule :C17H20N4SDegré de pureté :100% - ≥95%Couleur et forme :Yellowish Crystalline PowderMasse moléculaire :312.43Desvenlafaxine succinate hydrate
CAS :Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).Formule :C20H33NO7Degré de pureté :99.26%Couleur et forme :White Crystalline PowdeMasse moléculaire :399.48Dolasetron Mesylate hydrate
CAS :Dolasetron Mesylate hydrate blocks 5HT3 to prevent chemo and radiotherapy nausea.Formule :C20H26N2O7SDegré de pureté :99.86% - 99.9%Couleur et forme :SolidMasse moléculaire :438.49cis-(Z)-Flupentixol dihydrochloride
CAS :cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist.Formule :C23H27Cl2F3N2OSDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :507.44Ebalzotan
CAS :NAE-086 is a high-affinity and selective 5-HT(1A) receptor ligand with a K(i) value of 4.5 nM in membranes from rat hippocampus.Formule :C19H30N2O2Degré de pureté :99.08% - 99.41%Couleur et forme :SolidMasse moléculaire :318.45Relenopride
CAS :YKP 10811 (Relenopride) is a novel 5-HT4 receptor partial agonist, which can be used to study irritable bowel syndrome with constipation.Formule :C24H30ClFN4O4Degré de pureté :98.91% - 99.20%Couleur et forme :SoildMasse moléculaire :492.97MM 77 dihydrochloride
CAS :MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.Formule :C19H29Cl2N3O3Degré de pureté :100.00%Couleur et forme :SolidMasse moléculaire :418.36Ref: TM-T23007
1mg86,00€5mg157,00€10mg215,00€25mg472,00€50mg687,00€100mg938,00€500mg1.882,00€1mL*10mM (DMSO)281,00€AL 34662
CAS :AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also aFormule :C10H13N3ODegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :191.23Naluzotan hydrochloride
CAS :Naluzotan hydrochloride, a hERG K+ blocker (IC50: 3800 nM) and potent 5-HT1A agonist (IC50: ~20 nM, Ki: ~5.1 nM), is used in anxiety and depression studies.Formule :C23H39ClN4O3SDegré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :487.1PNU 22394 hydrochloride
CAS :PNU 22394 hydrochloride is a 5-HT2C agonist and partial 5-HT2A/5-HT2B agonistFormule :C13H17ClN2Degré de pureté :97.83%Couleur et forme :SolidMasse moléculaire :236.74RS-67333
CAS :RS-67333 is a partial agonist of 5-HT4R with neuroprotective effects.Formule :C19H29ClN2O2Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :352.9
