récepteur 5-HT
Les récepteurs 5-HT, également connus sous le nom de récepteurs de la sérotonine, sont un groupe de récepteurs couplés aux protéines G (GPCR) qui médiatisent les effets de la sérotonine, un neurotransmetteur impliqué dans la régulation de l'humeur, l'anxiété, le sommeil, l'appétit et d'autres processus physiologiques. Ces récepteurs sont divisés en plusieurs sous-types, chacun ayant des fonctions et des propriétés pharmacologiques distinctes. Les modulateurs des récepteurs 5-HT sont largement étudiés pour leurs rôles dans le traitement de la dépression, des troubles anxieux et d'autres affections neuropsychiatriques. Chez CymitQuimica, nous offrons une gamme de modulateurs des récepteurs 5-HT de haute qualité pour soutenir vos recherches en neuropharmacologie, troubles de l'humeur et signalisation GPCR.
Produits appartenant à la catégorie "récepteur 5-HT"
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ECPLA
CAS :ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.Formule :C21H25N3OCouleur et forme :SolidMasse moléculaire :335.44AC-90179 HCl
CAS :AC-90179 HCl: selective 5-HT2A inverse agonist, atypical antipsychotic, reduces hallucinogen-induced vasoconstriction.Formule :C23H31ClN2O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :402.96Ref: TM-T26543
1mg52,00€2mg74,00€5mg96,00€10mg137,00€25mg215,00€50mg391,00€100mg582,00€1mL*10mM (DMSO)127,00€Litoxetine HCl
Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.Formule :C16H20ClNODegré de pureté :98.98% - 99.19%Couleur et forme :SoildMasse moléculaire :277.79Ref: TM-T67956L
1mg97,00€5mg217,00€10mg325,00€25mg557,00€50mg797,00€100mg1.103,00€1mL*10mM (DMSO)208,00€Asenapine Maleate
CAS :Asenapine Maleate (Org 5222 maleate) is a second generation (atypical) antipsychotic agent that is taken sublingually.Formule :C21H20ClNO5Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :401.84Ref: TM-T1951
5mg35,00€10mg51,00€25mg80,00€50mg96,00€100mg135,00€200mg225,00€500mg373,00€1mL*10mM (DMSO)55,00€RS-127445
CAS :RS-127445 (MT500) is a selective 5-HT2B receptor antagonist with pKi of 9.5 and pIC50 of 10.4, exhibits >1000-fold selectivity against other 5-HT receptors.Formule :C17H16FN3Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :281.33AVN-492
CAS :AVN-49 is a potent and selective 5-HT6R Antagonist (Ki: 91 pM).Formule :C17H21N5O2SDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :359.45Ref: TM-T5179
1mg39,00€2mg49,00€5mg81,00€10mg120,00€25mg236,00€50mg354,00€100mg510,00€1mL*10mM (DMSO)89,00€Befiradol hydrochloride
CAS :Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.Formule :C20H23Cl2F2N3ODegré de pureté :99.1%Couleur et forme :SolidMasse moléculaire :430.32Levodropropizine
CAS :Levodropropizine ((S)-(-)-Dropropizine) is a histamine receptor inhibitor. It is used as an effective and very well tolerated peripheral antitussive drug.Formule :C13H20N2O2Degré de pureté :100% - 99.93%Couleur et forme :White Or Off White Crystalline PowderMasse moléculaire :236.31R 59-022
CAS :R 59-022 (DKGI-I) is a DGK inhibitor and a 5-HT Receptor antagonist that blocks filovirus internalization in host cells.Formule :C27H26FN3OSDegré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :459.58AVN-322
CAS :AVN-322 is a 5-HT6 receptor antagonist. 5-HT6R antagonists improves cognition in animal models of cognitive impairment.Formule :C17H20ClN5O2SDegré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :393.89BW 723C86
CAS :BW 723C86 is a 5-HT2B receptor agonist with anxiolytic effects, inducing overeating and reduced grooming in rats, useful in studying neurological disorders.Formule :C16H19ClN2OSDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :322.85Pardoprunox
CAS :Pardoprunox (SLV-308) is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.Formule :C12H15N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :233.27CI 169369
CAS :CI 169369 is a selective 5-HT2 receptor antagonist used in the study of anxiety and depression.Formule :C19H21ClN2SDegré de pureté :100%Couleur et forme :SoildMasse moléculaire :344.9Paroxetine hydrochloride
CAS :Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.Formule :C19H21ClFNO3Degré de pureté :98% - 99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :365.8265-HT2A receptor agonist-5
CAS :5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.Formule :C23H29N3OCouleur et forme :SolidMasse moléculaire :363.5Cannabidiolic acid methyl ester
CAS :Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.Formule :C23H32O4Couleur et forme :SolidMasse moléculaire :372.5Nefazodone hydrochloride
CAS :Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder.Formule :C25H33Cl2N5O2Degré de pureté :99% - 99.86%Couleur et forme :White SolidMasse moléculaire :506.47Ref: TM-T3275
5mg47,00€10mg70,00€25mg120,00€50mg216,00€100mg325,00€200mg472,00€500mg775,00€1mL*10mM (DMSO)77,00€LY334370
CAS :LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nMFormule :C21H22FN3ODegré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :351.42CJ 033466
CAS :CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect.Formule :C19H28ClN5ODegré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :377.91Ref: TM-T22671
1mg48,00€5mg101,00€10mg170,00€25mg270,00€50mg386,00€100mg520,00€1mL*10mM (DMSO)158,00€4-fluoro MBZP
CAS :4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.Formule :C12H17FN2Couleur et forme :SolidMasse moléculaire :208.28Intepirdine
CAS :Intepirdine (GSK-742457) is a highly selective 5-HT6 receptor antagonist, used in trials studying the treatment of Alzheimer's Disease.Formule :C19H19N3O2SDegré de pureté :98% - 98.63%Couleur et forme :SolidMasse moléculaire :353.44Lesopitron HCl
CAS :Lesopitron HCl is a 5-HT1A receptor agonist with anxiolytic effects that reverses dark avoidance behavior associated with cocaine withdrawal in mice.Formule :C15H22Cl2N6Degré de pureté :97.05% - 98.18%Couleur et forme :SoildMasse moléculaire :357.28Minesapride
CAS :Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.Formule :C21H31ClN4O5Degré de pureté :99% - 99.35%Couleur et forme :SolidMasse moléculaire :454.95Ref: TM-T28043L
1mg115,00€5mg245,00€10mg363,00€25mg562,00€50mg802,00€100mg1.111,00€200mg1.491,00€1mL*10mM (DMSO)284,00€LP44 hydrochloride
CAS :LP44 hydrochloride is a 5-HT7 agonist with analgesic effects on formalin-induced orofacial pain in mice and can be used to study neuroinflammation.Formule :C27H38ClN3OSDegré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :488.13Methiothepin mesylate
CAS :Methiothepin mesylate (Metitepine mesylate) is a potent and non-selective 5-HT2 receptor antagonist, used as an antipsychotic.Formule :C21H28N2O3S3Degré de pureté :98% - 99.92%Couleur et forme :SolidMasse moléculaire :452.65Pheniramine maleate
CAS :Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors.Formule :C16H20N2·C4H4O4Degré de pureté :99.85%Couleur et forme :Physical Description White Powder With A Faint Amine-Like Odor Melting Point 107°CMasse moléculaire :356.42Tipindole
CAS :Tipindole is a serotonin antagonist utilized in research related to depression.Formule :C16H20N2O2SCouleur et forme :SolidMasse moléculaire :304.41Cerlapirdine
CAS :Cerlapirdine (PF-05212365), a 5-HT6 receptor antagonist, is in trials for Alzheimer's and schizophrenia cognition issues.Formule :C22H23N3O3SDegré de pureté :98.60%Couleur et forme :SolidMasse moléculaire :409.5Ref: TM-T30798
1mg81,00€5mg170,00€10mg274,00€25mg543,00€50mg780,00€100mg1.074,00€1mL*10mM (DMSO)198,00€SEP-363856 hydrochloride
CAS :SEP-363856 hydrochloride is an oral, CNS-active psychotropic for schizophrenia with a non-D2/5-HT2A mechanism.Formule :C9H14ClNOSDegré de pureté :99.86% - 99.99%Couleur et forme :SolidMasse moléculaire :219.73Ref: TM-T12899L
1mg70,00€2mg92,00€5mg154,00€10mg243,00€25mg425,00€50mg628,00€100mg938,00€500mg1.882,00€1mL*10mM (DMSO)169,00€AAZ-A 154 hydrochloride
CAS :AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.Formule :C14H21ClN2OCouleur et forme :SolidMasse moléculaire :268.78Triazolomethylindole-3-acetic acid
CAS :Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.Formule :C13H12N4O2Couleur et forme :SolidMasse moléculaire :256.26Cannabigerol
CAS :Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; alsoFormule :C21H32O2Degré de pureté :99.23% - 99.92%Couleur et forme :SolidMasse moléculaire :316.48Ref: TM-TN1465
1mg145,00€2mg215,00€5mg314,00€10mg474,00€25mg808,00€50mg1.111,00€100mg1.501,00€1mL*10mM (DMSO)324,00€Serotonin
CAS :Serotonin (5-hydroxytryptamine) is a natural product from animalsFormule :C10H12N2ODegré de pureté :95.94% - 99.92%Couleur et forme :SolidMasse moléculaire :176.22Ref: TM-TN2437
1mg78,00€5mg139,00€10mg202,00€25mg360,00€50mg540,00€100mg810,00€500mg1.596,00€1mL*10mM (DMSO)117,00€m-Chlorophenylbiguanide hydrochloride
CAS :m-Chlorophenylbiguanide hydrochloride is a 5-HT3 receptor agonist.Formule :C8H11Cl2N5Degré de pureté :99.43% - 99.87%Couleur et forme :SolidMasse moléculaire :248.11Viloxazine
CAS :Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activityFormule :C13H19NO3Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :237.29Fluoxetine
CAS :Fluoxetine (LY-110140), a specific serotonin inhibitor, serves as an antidepressant with fewer side-effects.Formule :C17H18F3NODegré de pureté :99.07% - 99.28%Couleur et forme :SolidMasse moléculaire :309.332-Methyl-N,N-dimethyltryptamine
CAS :2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.Formule :C13H18N2Couleur et forme :SolidMasse moléculaire :202.3Bromperidol
CAS :Bromperidol (R-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic.Formule :C21H23BrFNO2Degré de pureté :99.89%Couleur et forme :Tan SolidMasse moléculaire :420.32Cinitapride
CAS :Cinitapride (Blaston) treats acid reflux and gastric issues, targeting 5-HT2, 5-HT1, and 5-HT4 receptors.Formule :C21H30N4O4Degré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :402.49Ref: TM-T21385
1mg78,00€5mg163,00€10mg253,00€25mg505,00€50mg730,00€100mg1.026,00€1mL*10mM (DMSO)187,00€p-MPPF
CAS :p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.Formule :C25H27FN4O2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :434.51Mirtazapine
CAS :Mirtazapine is a unique tetracyclic antidepressant, may cause temporary liver enzyme elevation, and is linked to rare liver injury.Formule :C17H19N3Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :265.35PRX933 hydrochloride
CAS :PRX933 hydrochloride (GW876167 hydrochloride) is an agonist of 5-HT2C receptor and can be used in studies about hypertension acute treatment.Formule :C16H22ClN5O2Degré de pureté :97.99% - 99.72%Couleur et forme :SolidMasse moléculaire :351.84Ref: TM-T12565
1mg356,00€5mg568,00€10mg907,00€25mg1.339,00€50mg1.815,00€100mg2.432,00€1mL*10mM (DMSO)652,00€Iprindole
CAS :Iprindole, a tricyclic indole antidepressant, is a dual weak inhibitor of noradrenaline and 5-HT uptake [1].Formule :C19H28N2Degré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :284.44Ref: TM-T37015
2mg37,00€5mg52,00€10mg80,00€25mg154,00€50mg266,00€100mg455,00€200mg652,00€1mL*10mM (DMSO)84,00€MDL 100009
CAS :MDL 100009, the S-enantiomer of MDL 100151 and the opposite enantiomer of MDL 100907, is a selective antagonist of 5-HT2A.Formule :C22H28FNO3Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :373.46Ref: TM-T22359
1mg148,00€2mg188,00€5mg283,00€10mg424,00€25mg655,00€50mg883,00€100mg1.169,00€200mg1.596,00€1mL*10mM (DMSO)335,00€Tropisetron
CAS :Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.Formule :C17H20N2O2Degré de pureté :99.95%Couleur et forme :White SolidMasse moléculaire :284.35Flucopride
CAS :Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.Formule :C22H33FN2O2Couleur et forme :SolidMasse moléculaire :376.51GR 46611
CAS :GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.Formule :C23H27N3O2Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :377.48Sertindole
CAS :Sertindole, atypical antipsychotic, targets D2, 5-HT1D, 5-HT2A, 5-HT2C receptors (Kds: 2.7, 20, 0.14, 6 nM).Formule :C24H26ClFN4ODegré de pureté :99.74%Couleur et forme :Off-White To Pale Yellow SolidMasse moléculaire :440.94Xanthotoxol
CAS :Xanthotoxol (Psoralen) is a bioactive furocoumarin with anti-inflammatory, antioxidant, 5-HT antagonist, and neuroprotective properties.Formule :C11H6O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :202.16SKF-83566
CAS :SKF-83566: Blood-brain permeable, orally active D1 dopamine antagonist; weaker 5-HT2 antagonist, Ki=11 nM.Formule :C17H18BrNODegré de pureté :95.00% - 99.82%Couleur et forme :SolidMasse moléculaire :332.23
