récepteur 5-HT
Les récepteurs 5-HT, également connus sous le nom de récepteurs de la sérotonine, sont un groupe de récepteurs couplés aux protéines G (GPCR) qui médiatisent les effets de la sérotonine, un neurotransmetteur impliqué dans la régulation de l'humeur, l'anxiété, le sommeil, l'appétit et d'autres processus physiologiques. Ces récepteurs sont divisés en plusieurs sous-types, chacun ayant des fonctions et des propriétés pharmacologiques distinctes. Les modulateurs des récepteurs 5-HT sont largement étudiés pour leurs rôles dans le traitement de la dépression, des troubles anxieux et d'autres affections neuropsychiatriques. Chez CymitQuimica, nous offrons une gamme de modulateurs des récepteurs 5-HT de haute qualité pour soutenir vos recherches en neuropharmacologie, troubles de l'humeur et signalisation GPCR.
Produits appartenant à la catégorie "récepteur 5-HT"
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BRL 54443
CAS :BRL 54443 is a potent 5-HT1E/1F receptor agonist (pKi values are 8.7 and 8.9 respectively).Formule :C14H18N2ODegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :230.31Melitracen hydrochloride
CAS :Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.Formule :C21H26ClNDegré de pureté :99.99%Couleur et forme :Crystalline SolidMasse moléculaire :327.9Ref: TM-T4274
10mg47,00€25mg67,00€50mg87,00€100mg116,00€200mg170,00€500mg279,00€1mL*10mM (DMSO)50,00€NLX-204 hydrochloride(2170405-10-2 free base)
NLX-204 hydrochloride is a potent and selective ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist(pKi = 10.19).Formule :C20H23Cl2F2N3O2Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :446.32Rotundine
CAS :Rotundine (Gindarine) (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.Formule :C21H25NO4Degré de pureté :100% - 99.8%Couleur et forme :Off-White SolidMasse moléculaire :355.43Iloperidone
CAS :Iloperidone (HP 873) is an atypical antipsychotic agent that is used for treatment of schizophrenia.Formule :C24H27FN2O4Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :426.48EMDT
CAS :EMDT oxalate is a selective 5-HT6 agonist, and has antidepressant effects.Formule :C15H22N2ODegré de pureté :98.33% - 98.46%Couleur et forme :SolidMasse moléculaire :246.35Ref: TM-T11183
1mg92,00€2mg125,00€5mg170,00€10mg213,00€25mg474,00€50mg688,00€100mg938,00€500mg1.882,00€1mL*10mM (DMSO)170,00€Alniditan
CAS :Alniditan is a receptors agonist of 5-HT1B/1D in HEK 293 cells (IC50: 1.7 and 1.3 nM). For 5-HT1B/1D receptors, the pKi values are 8.96 and 9.40, respectively.Formule :C17H26N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.41Ziprasidone hydrochloride monohydrate
CAS :Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychoticFormule :C21H21ClN4OS·HCl·H2ODegré de pureté :98% - 99.83%Couleur et forme :Off-White PowderMasse moléculaire :467.12Lurasidone hydrochloride
CAS :Lurasidone HCl: Atypical antipsychotic, treats schizophrenia & bipolar, affects dopamine, serotonin & adrenergic receptors.Formule :C28H36N4O2S·HClDegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :529.14(+)-OSU 6162
CAS :(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.Formule :C15H23NO2SDegré de pureté :99.81%Couleur et forme :SoildMasse moléculaire :281.41Ref: TM-T60027
1mg77,00€5mg155,00€10mg220,00€25mg338,00€50mg472,00€100mg632,00€200mg853,00€1mL*10mM (DMSO)163,00€Donitriptan hydrochloride
CAS :Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectivelyFormule :C23H26ClN5O2Degré de pureté :99.8% - 99.8%Couleur et forme :SolidMasse moléculaire :439.94Ref: TM-T21666
2mg40,00€5mg49,00€10mg64,00€25mg135,00€50mg240,00€100mg339,00€200mg439,00€500mgÀ demanderSumatriptan succinate
CAS :Sumatriptan succinate (GR 43175), a serotonin1 (5-HT1) receptor agonist, is used in the acute treatment of a migraine headache.Formule :C18H27N3O6SDegré de pureté :97.53% - 99.51%Couleur et forme :White PowderMasse moléculaire :413.49Jatrorrhizine chloride
CAS :Jatrorrhizine chloride (Neprotine chloride) is an alkaloid isolated from Rhizoma coptidis with neuroprotective, antimicrobial, and antiplasmodial activities.Formule :C20H20ClNO4Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :373.8rac Desmethyl Citalopram Hydrochloride
CAS :rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.Formule :C19H20ClFN2ODegré de pureté :96.14%Couleur et forme :SolidMasse moléculaire :346.83Tegaserod
CAS :Tegaserod is a 5-HT4R agonist and 5-HT2B receptor antagonist with antitumor activity used in the treatment of irritable bowel syndrome (IBS).Formule :C16H23N5ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :301.39Lurasidone
CAS :Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7(IC50=1.68 and 0.495 nM, respectively).It also a partial agonist of 5-HT1A receptor(IC50 : 6Formule :C28H36N4O2SDegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :492.68PZ-1922
PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.Degré de pureté :98%Couleur et forme :Odour SolidAlprenolol
CAS :Alprenolol (Alpheprol) is a non-selective β-adrenergic receptor (β-AR) antagonist that is also an antagonist of the serotonin (5-HT) receptor subtypes 5-HT1AFormule :C15H23NO2Degré de pureté :99.73% - 99.78%Couleur et forme :SolidMasse moléculaire :249.35Mebhydrolin napadisylate
CAS :Mebhydrolin napadisylate (Incidal) is an antihistamine used to relieve allergic symptoms caused by histamine release, including nasal allergies and allergicFormule :C19H20N2C10H8O6S2Degré de pureté :99.35% - 99.77%Couleur et forme :White Or Almost White CrystallineMasse moléculaire :420.52Zacopride hydrochloride
CAS :Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.Formule :C15H20ClN3O2·HClDegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :346.26Ref: TM-T5336
1mg46,00€5mg87,00€10mg144,00€25mg283,00€50mg454,00€100mg655,00€200mg930,00€1mL*10mM (DMSO)97,00€Protriptyline hydrochloride
CAS :Protriptyline HCl: a tricyclic antidepressant that increases norepinephrine and serotonin levels and has anticholinergic effects.Formule :C19H21N·HClDegré de pureté :98.54% - 99.98%Couleur et forme :SolidMasse moléculaire :299.84Sulamserod
CAS :Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular relatedFormule :C19H28ClN3O5SDegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :445.965-HT2 antagonist 1
CAS :5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity.Formule :C22H29FN4O2Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :400.49Ref: TM-T12597
1mg678,00€5mg1.359,00€10mg1.833,00€25mg2.727,00€50mg3.676,00€100mg4.969,00€1mL*10mM (DMSO)1.605,00€Lumateperone
CAS :Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).Formule :C24H28FN3ODegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :393.5Rilapine
CAS :Rilapine (Rilapinum) is an antipsychotic compound that shows high affinity for 5-HT6 receptors and can be used to study neurological disorders.Formule :C22H20ClN3Degré de pureté :99% - 99.66%Couleur et forme :SolidMasse moléculaire :361.87Masupirdine mesylate
CAS :Masupirdine mesylate (SUVN-502 mesylate) is a 5-HT6 receptor antagonist.Masupirdine mesylate is used to study neurological disorders such as Alzheimer's diseaseFormule :C23H32BrN3O9S3Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :670.61Lerisetron
CAS :Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity.Formule :C18H20N4Degré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :292.38SB-200646
CAS :SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptorFormule :C15H14N4ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :266.3Ref: TM-T8357
1mg97,00€2mg150,00€5mg207,00€10mg311,00€25mg525,00€50mg757,00€100mg1.035,00€1mL*10mM (DMSO)216,00€AVN 322 free base
CAS :AVN 322 free base is an orally available, selective and potent 5-HT6R antagonist for the study of neuropathic system disorders such as Alzheimer's disease (AD) and schizophrenia.Formule :C17H19N5O2SDegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :357.435-HT2A&5-HT2C agonist-1
CAS :5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.Formule :C14H20N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :232.325-HT6R antagonist 6
5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.Formule :C24H26N4O2SMasse moléculaire :434.55Masupirdine free base
CAS :Masupirdine free base (SUVN-502 free base) is a 5-HT6 receptor antagonist that can be used to study neurological disorders like Alzheimer's disease.Formule :C21H24BrN3O3SDegré de pureté :97.40% - 98.67%Couleur et forme :SolidMasse moléculaire :478.4Temanogrel
CAS :Temanogrel (APD791) is a highly selective antagonist of the 5-HT2A receptor (Ki: 4.9 nM).Formule :C24H28N4O4Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :436.5Ref: TM-T17033
1mg69,00€5mg156,00€10mg225,00€25mg375,00€50mg533,00€100mg723,00€200mg938,00€1mL*10mM (DMSO)170,00€Lesopitron
CAS :Lesopitron: anxiolytic, 5-HT1A agonist, treats rodent anxiety, counters benzodiazepine withdrawal, low toxicity, no alcohol/barbiturate interaction.Formule :C15H21ClN6Degré de pureté :98.60% - 98.92%Couleur et forme :SolidMasse moléculaire :320.82Harmine
CAS :Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.Formule :C13H12N2ODegré de pureté :98.29% - 99.92%Couleur et forme :Off-White SolidMasse moléculaire :212.258-Hydroxy-DPAT hydrobromide
CAS :8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19.Formule :C16H26BrNODegré de pureté :98.90% - 99.09%Couleur et forme :SolidMasse moléculaire :328.29Ketanserin
CAS :Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Formule :C22H22FN3O3Degré de pureté :99.19% - 99.73%Couleur et forme :SolidMasse moléculaire :395.43CP94253 hydrochloride
CAS :CP94253 hydrochloride: selective 5-HT1B agonist, Ki=2 nM; less active on 5-HT1A/D/C/2 (Ki=89/49/860/1600 nM).Formule :C15H20ClN3ODegré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :293.79Ref: TM-T22689
5mg70,00€10mg96,00€25mg216,00€50mg354,00€100mg567,00€200mg787,00€1mL*10mM (DMSO)70,00€Clozapine
CAS :Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent.Formule :C18H19ClN4Degré de pureté :99.91% - 99.93%Couleur et forme :Yellow Crystals From Acetone-Petroleum Ether SolidMasse moléculaire :326.82Ref: TM-T0455
1g449,00€10mg35,00€25mg52,00€50mg70,00€100mg96,00€200mg170,00€500mg303,00€1mL*10mM (DMSO)47,00€L-694,247
CAS :L-694,247 is a 5-HT receptor agonist with affinity for 5-HT1D, 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1E receptors, and can be used to study neurological diseases.Formule :C20H21N5O3SDegré de pureté :98.36%Couleur et forme :White SolidMasse moléculaire :411.48Naftopidil dihydrochloride
CAS :Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.Formule :C24H28N2O3·2HClDegré de pureté :99.76%Couleur et forme :White SolidMasse moléculaire :465.41Phenylbiguanide
CAS :Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)Formule :C8H11N5Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :177.21LP-533401 hydrochloride
CAS :LP-533401 hydrochloride is a peripheral Tph inhibitor that does not cross the BBB and can be used to study periodontal disease and hepatic steatosis.Formule :C27H23ClF4N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :562.94Brexpiprazole HCl
CAS :Brexpiprazole HCl (OPC 34712 dihydrochloride) is a new antipsychotic drug.Formule :C25H27N3O2S·xHClDegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :433.6Ref: TM-T8690
1mg131,00€5mg286,00€10mg430,00€25mg710,00€50mg998,00€100mg1.349,00€500mg2.688,00€1mL*10mM (DMSO)338,00€S 16924
CAS :S 16924 is a 5-HT 1A agonist with potential anxiolytic effects and may be useful in the study of neurologic disorders.Formule :C22H24FNO4Degré de pureté :98.23% - 99.45%Couleur et forme :SolidMasse moléculaire :385.43Methamnetamine hydrochloride
CAS :Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.Formule :C14H18ClNCouleur et forme :SolidMasse moléculaire :235.75Palonosetron
CAS :Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).Formule :C19H24N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :296.41Syk Inhibitor II
CAS :Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).Formule :C14H15F3N6ODegré de pureté :97.63%Couleur et forme :SolidMasse moléculaire :340.3SB-224289 hydrochloride
CAS :SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.Formule :C32H33ClN4O3Degré de pureté :97.82% - 98.09%Couleur et forme :SolidMasse moléculaire :557.085-HT2A receptor agonist-3
CAS :5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.Formule :C21H26BrNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.34
