COX
Les inhibiteurs de la cyclooxygénase (COX) sont des composés qui bloquent l'activité des enzymes COX, impliquées dans la production de prostaglandines, des médiateurs clés de l'inflammation et de la douleur. En neurosciences, les inhibiteurs de la COX sont étudiés pour leur potentiel à réduire la neuroinflammation, qui est impliquée dans diverses maladies neurodégénératives telles que la maladie d'Alzheimer, la maladie de Parkinson et la sclérose en plaques. En inhibant la COX, ces composés peuvent aider à atténuer les processus inflammatoires dans le cerveau et à protéger contre les lésions neuronales. Chez CymitQuimica, nous fournissons une gamme d'inhibiteurs de la COX pour soutenir vos recherches sur la neuroinflammation, la gestion de la douleur et les maladies neurodégénératives.
Produits appartenant à la catégorie "COX"
Trier par
Madecassic acid
CAS :Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Formule :C30H48O6Degré de pureté :98.80% - 99.69%Couleur et forme :SolidMasse moléculaire :504.7Pemedolac
CAS :Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.Formule :C22H23NO3Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :349.42syringaldehyde
CAS :Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species, moderately inhibiting COX-2 activity.Formule :C9H10O4Degré de pureté :99.24%Couleur et forme :Light Yellow-Green To Brown Crystalline PowderMasse moléculaire :182.17Ampiroxicam
CAS :Ampiroxicam (Flucam) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.Formule :C20H21N3O7SDegré de pureté :97.27% - 99.2%Couleur et forme :PowderMasse moléculaire :447.46Adelmidrol
CAS :Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Formule :C13H26N2O4Degré de pureté :99.35% - 99.73%Couleur et forme :SolidMasse moléculaire :274.36Neral
CAS :Neral, a monoterpenoid compound, exhibits anti-inflammatory and anticancer activities. It inhibits TNF-α and IL-6, along with inflammatory mediators such as pro-IL-1β, iNOS, COX-2, and NLRP-3.Formule :C10H16OCouleur et forme :SolidMasse moléculaire :152.23S-(+)-Marmesin
CAS :S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.Formule :C14H14O4Degré de pureté :98.00% - ≥98%Couleur et forme :SolidMasse moléculaire :246.26Ibuprofen Lysine
CAS :Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.Formule :C19H32N2O4Degré de pureté :99.66%Couleur et forme :CoaMasse moléculaire :352.47Carprofen
CAS :Formule :C15H12ClNO2Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :273.72Flunixin meglumine
CAS :Flunixin meglumine (Banamine) is an effective inhibitor of the enzyme cyclooxygenase with anti-inflammatory and antipyretic activity.Formule :C21H28F3N3O7Degré de pureté :100% - 99.86%Couleur et forme :SolidMasse moléculaire :491.46COX-2-IN-46
COX-2-IN-46 (compound 5m) serves as a potent anti-inflammatory and analgesic agent. It demonstrates a significant inhibitory action on COX-2, with an IC 50 value of 87.74 nM.Formule :C28H19F2N3SCouleur et forme :SolidMasse moléculaire :467.53DuP-697
CAS :DuP-697 is an irreversible, specific COX-2 inhibitor with IC50 values of 10 nM and 800 nM for human COX-2 and COX-1.Cost-effective and quality-assured.Formule :C17H12BrFO2S2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :411.31Ref: TM-T15181
1mg52,00€5mg104,00€10mg154,00€25mg249,00€50mg369,00€100mg543,00€200mg772,00€1mL*10mM (DMSO)124,00€Dipyrone
CAS :Formule :C13H16N3NaO4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.3386Butyl 2-[[3-(Trifluoromethyl)phenyl]amino]benzoate
CAS :Formule :C18H18F3NO2Degré de pureté :>98.0%(HPLC)(N)Couleur et forme :Colorless to Yellow clear liquidMasse moléculaire :337.34Diclofenac Sodium Salt
CAS :Formule :C14H10Cl2NNaO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :318.13052-O-Sinapoyl makisterone A
Compound 2, formally known as 2-O-Sinapoyl makisterone A, is a sinapinic acid-ecdysterone hybrid that acts as a selective inhibitor of COX-2, effectivelyFormule :C39H56O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :700.86Tepoxalin
CAS :Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.Formule :C20H20ClN3O3Degré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :385.84Ref: TM-T7724
1mg56,00€5mg119,00€10mg170,00€25mg393,00€50mg587,00€100mg835,00€200mg1.130,00€1mL*10mM (DMSO)139,00€Byakangelicol
CAS :Byakangelicol may reduce P-gp at BBB and has anti-inflammatory effects by hindering COX-2 and PGE2 in A549 cells.Formule :C17H16O6Degré de pureté :99.15% - 99.55%Couleur et forme :SolidMasse moléculaire :316.31Salicylic acid
CAS :Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.Formule :C7H6O3Degré de pureté :98.04% - 98.83%Couleur et forme :White Solid PowderMasse moléculaire :138.12RHC 80267
CAS :RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)Formule :C20H34N4O4Degré de pureté :99.54%Couleur et forme :White SolidMasse moléculaire :394.51Crocin II
CAS :Crocin II combats gastric and liver injuries, reduces inflammation, apoptosis, oxidative stress, and may lower lipid levels and have antidepressant effects.Formule :C38H54O19Degré de pureté :98% - 99.19%Couleur et forme :SolidMasse moléculaire :814.82β-Amyrone
CAS :beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM.Formule :C30H48ODegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :424.7FPL 62064
CAS :FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandinFormule :C16H15N3ODegré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :265.31Ref: TM-T8356
1mg40,00€5mg80,00€10mg116,00€25mg198,00€50mg299,00€100mg449,00€200mg627,00€1mL*10mM (DMSO)99,00€Eltenac
CAS :Eltenac, a cyclooxygenase (COX) inhibitor, is used potentially for the treatment of pain.Formule :C12H9Cl2NO2SDegré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :302.18Chlorotrianisene
CAS :Chlorotrianisene, a synthetic SERM, is orally active, lipophilic, and has estrogenic and antiestrogenic effects.Formule :C23H21ClO3Degré de pureté :98.88% - 99.03%Couleur et forme :Crystals From Methanol Physical Description Small White Crystals Or White Powder Softens At 226°F Odorless (Ntp 1992)Masse moléculaire :380.86Ref: TM-T2569
1mg59,00€5mg127,00€10mg205,00€25mg344,00€50mg512,00€100mg730,00€200mg998,00€1mL*10mM (DMSO)139,00€FK 3311
CAS :FK 3311 (COX-2 Inhibitor V) is a cell permeable and orally available sulfonanilide that acts as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (Formule :C15H13F2NO4SDegré de pureté :97.98%Couleur et forme :SolidMasse moléculaire :341.33Ref: TM-T7207
2mg46,00€5mg66,00€10mg96,00€25mg165,00€50mg250,00€100mg374,00€200mg547,00€1mL*10mM (DMSO)88,00€Diclofenac Diethylamine
CAS :Formule :C14H11Cl2NO2·C4H11NDegré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :369.29[8]-Shogaol
CAS :[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.Formule :C19H28O3Degré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :304.42Ref: TM-T5430
1mg96,00€5mg208,00€10mg359,00€25mg592,00€50mg837,00€100mg1.121,00€1mL*10mM (DMSO)230,00€Suprofen
CAS :Formule :C14H12O3SDegré de pureté :>98.0%(GC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :260.31Felbinac
CAS :Felbinac (Dapson), a topical medicine, is an active metabolite of fenbufen. Felbinac is belonging to the family of NSAIDs of the arylpropionic acid class.Formule :C14H12O2Degré de pureté :99.47%Couleur et forme :Beige Beige PowderMasse moléculaire :212.24NF157
CAS :NF157, a selective P2Y11 antagonist with pKi 7.35, lowers MMP-3/MMP-13, aiding OA treatment; IC50s: P2Y11 463 nM, P2Y1 1811 μM, P2Y2 170 μM.Formule :C49H28F2N6Na6O23S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1437.1Suprofen
CAS :Formule :C14H12O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :260.3083Thioflosulide
CAS :Thioflosulide (L-745337) is a selective and potent COX2 inhibitor (IC50: 2.3 nM) with anti-inflammatory activity for the study of gastric ulcers.Formule :C16H13F2NO3S2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :369.41Nepafenac
CAS :Nepafenac (AHR 9434) is an NSAID that acts as a cyclooxygenase inhibitor.Formule :C15H14N2O2Degré de pureté :98.94% - 99.88%Couleur et forme :SolidMasse moléculaire :254.28SULINDAC SULFIDE
CAS :Formule :C20H17FO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :340.4112Aspirin
CAS :Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.Formule :C9H8O4Degré de pureté :99.78% - 99.91%Couleur et forme :White Solid CrystallineMasse moléculaire :180.16Bismuth Subsalicylate
CAS :Bismuth Subsalicylate, Pepto-Bismol's active ingredient, treats nausea, heartburn, indigestion, diarrhea, and stomach upset.Formule :C7H5BiO4Degré de pureté :100%Couleur et forme :White Solid PowderMasse moléculaire :362.092-[(2,3-Dimethylphenyl)amino]benzoic acid
CAS :Formule :C15H15NO2Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :241.2851Bromfenac sodium hydrate
CAS :Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a NSAID with analgesic and anti-inflammatory effects.Formule :C15H12BrNO3H2O·NaDegré de pureté :91.85% - 99.65%Couleur et forme :SolidMasse moléculaire :383.17COX-2-IN-33
COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.Formule :C20H13ClF3N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :479.8N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide
CAS :Formule :C13H18N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :314.3574Hexahydrocurcumin
CAS :Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.Formule :C21H26O6Degré de pureté :99.43% - 99.77%Couleur et forme :SolidMasse moléculaire :374.43Ref: TM-TQ0288
1mg119,00€5mg283,00€10mg418,00€25mg692,00€50mg938,00€100mg1.320,00€500mg2.642,00€1mL*10mM (DMSO)313,00€Acemetacin
CAS :Acemetacin (TVX 1322) is a carboxymethyl ester of indometacin.Formule :C21H18ClNO6Degré de pureté :99.26%Couleur et forme :Light Yellow SolidMasse moléculaire :415.82Deracoxib
CAS :Deracoxib (SC 46) is a selective COX-2 inhibitor, non-steroidal, non-narcotic anti-inflammatory drug with an IC50 of 70-150 μM for osteosarcoma cells.Formule :C17H14F3N3O3SDegré de pureté :100% - 99.81%Couleur et forme :SolidMasse moléculaire :397.37Indolo[2,1-b]quinazoline-6,12-dione
CAS :Formule :C15H8N2O2Degré de pureté :96%Couleur et forme :SolidMasse moléculaire :248.23624-Biphenylacetic Acid
CAS :Formule :C14H12O2Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Orange to Green powder to crystalMasse moléculaire :212.25Clonixin
CAS :Formule :C13H11ClN2O2Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :262.69Tyrphostin AG 490
CAS :Formule :C17H14N2O3Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :294.31Insulin levels modulator
CAS :Insulin level regulators can be used to treat diabetes.Formule :C21H23N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.52Metyrosine
CAS :Metyrosine: antihypertensive, tyrosine hydroxylase inhibitor, controls COX-2, lowers blood pressure.Formule :C10H13NO3Degré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :195.22
![Butyl 2-[[3-(Trifluoromethyl)phenyl]amino]benzoate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb-webp%2FB5391.webp&w=3840&q=75)
![[8]-Shogaol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT5430.webp&w=3840&q=75)
![2-[(2,3-Dimethylphenyl)amino]benzoic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA0039LC.webp&w=3840&q=75)
![N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA0035EW.webp&w=3840&q=75)
![Indolo[2,1-b]quinazoline-6,12-dione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA0010E4.webp&w=3840&q=75)
