Cellules souche et Dérivés
Les inhibiteurs de cellules souches sont des composés qui ciblent spécifiquement les voies de signalisation et les protéines impliquées dans le maintien, la différenciation et la prolifération des cellules souches. Ces inhibiteurs sont cruciaux pour comprendre la biologie des cellules souches et pour développer des stratégies visant à manipuler les cellules souches à des fins thérapeutiques, telles que la médecine régénérative et le traitement du cancer. En contrôlant le destin des cellules souches, ces inhibiteurs peuvent aider à orienter la différenciation des cellules souches en types cellulaires spécifiques ou à prévenir une croissance cellulaire indésirable. Chez CymitQuimica, nous offrons une sélection d'inhibiteurs de cellules souches de haute qualité pour soutenir vos recherches en biologie des cellules souches, biologie du développement et médecine régénérative.
Sous-catégories appartenant à la catégorie "Cellules souche et Dérivés"
- Gamma-sécrétase
- Hérisson/Smoothened
- Voie de signalisation Hippo
- JAK
- Porc-épic
- ROCK
- STAT
- Cellules souches
- TGF-beta/Smad
- Wnt/beta-caténine
Affichez 2 plus de sous-catégories
Produits appartenant à la catégorie "Cellules souche et Dérivés"
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Demcizumab
CAS :Demcizumab (OMP 21M18), an anti-DLL4 antibody, inhibits the Notch pathway and fights various cancers solo or with chemo.Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :145.34 kDaDPP
CAS :DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstratingFormule :C36H40Cl2N2O10PtDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :926.7BMS-983970
CAS :BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.Formule :C26H26F4N4O3Couleur et forme :SolidMasse moléculaire :518.5Enoticumab
CAS :Enoticumab (REGN421) is a fully human IgG1 monoclonal antibody with anticancer activity that inhibits cancer cell growth.Couleur et forme :LiquidAJI-100
CAS :AJI-100 serves as a dual-target inhibitor, effectively blocking Aurora kinase A and JAK2, with respective IC50 values of 12.7 nM and 18.5 nM. It inhibits T cell mitosis and cell polarity by directly targeting Aurora kinase A and reduces STAT3 phosphorylation by inhibiting JAK2 activation, consequently diminishing the differentiation of TH1 and TH17 cells. This compound is utilized in researching immune response regulation and the prevention of graft-versus-host disease (GVHD).Formule :C17H14FN5OCouleur et forme :SolidMasse moléculaire :323.32Ripasudil free base
CAS :Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent.Formule :C15H18FN3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.39Ref: TM-T7492
1mg80,00€5mg159,00€10mg250,00€25mg558,00€50mg922,00€100mg1.540,00€1mL*10mM (DMSO)170,00€PMMB-187
CAS :PMMB-187, a selective STAT3 inhibitor, exhibits an IC50 of 1.81 μM in MDA-MB-231 cells. This compound induces apoptosis in MDA-MB-231 cells by inhibiting STAT3 transcriptional activity and nuclear translocation, reducing mitochondrial membrane potential, increasing reactive oxygen species (ROS) production, and upregulating the expression of apoptosis-related proteins. PMMB-187 is useful for research in the field of cancer.Formule :C27H23BrN2O6S2Couleur et forme :SolidMasse moléculaire :615.52TCS 21311
CAS :TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.Formule :C27H25F3N4O4Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :526.51CSNK2-IN-2
CSNK2-IN-2 (compound 2) is an orally active inhibitor of CSNK2. It is utilized in antiviral research.Formule :C25H30FN9OCouleur et forme :SolidMasse moléculaire :491.56Casein kinase 1δ-IN-3
CAS :Casein kinase 1δ-IN-3 (Casein kinase 1δ-IN-3) (Compound 23a) is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M.Formule :C17H16N2O2SDegré de pureté :99.42%Couleur et forme :SoildMasse moléculaire :312.39Ref: TM-T64350
1mg38,00€5mg73,00€10mg115,00€25mg235,00€50mg373,00€100mg560,00€200mg797,00€1mL*10mM (DMSO)87,00€Wnt pathway activator 2
CAS :Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.Formule :C17H15NO4Degré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :297.31Ref: TM-T13345
1mg49,00€5mg105,00€10mg169,00€25mg344,00€50mg562,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)116,00€H-1152 dihydrochloride
CAS :H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.Formule :C16H23Cl2N3O2SDegré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :392.34Ref: TM-T35328
1mg64,00€5mg142,00€10mg227,00€25mg439,00€50mg692,00€100mg938,00€1mL*10mM (DMSO)156,00€Rat GDF10(GrowthDifferentiation Factor 10) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat GDF10. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat GDF10. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat GDF10, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat GDF10 in the samples is then determined by comparing the OD of the samples to the standard curve.Couleur et forme :Colourless TransparentliquidITD-1
CAS :ITD-1 is a potent and highly selective TGFβ pathway inhibitor.Formule :C27H29NO3Degré de pureté :100% - 99.89%Couleur et forme :SolidMasse moléculaire :415.52MSC-5046
MSC-5046 is a selective inhibitor of TEAD1.Formule :C24H18F3N5O3Couleur et forme :SolidMasse moléculaire :481.43JW74
CAS :JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).Formule :C24H20N6O2SDegré de pureté :95.00%Couleur et forme :SolidMasse moléculaire :456.52SB 216763
CAS :SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).Formule :C19H12Cl2N2O2Degré de pureté :99.13% - 99.61%Couleur et forme :SolidMasse moléculaire :371.22Ref: TM-T3077
2mg39,00€5mg52,00€10mg79,00€25mg131,00€50mg197,00€100mg334,00€500mg803,00€1mL*10mM (DMSO)52,00€Protosappanin A
CAS :Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.Formule :C15H12O5Degré de pureté :100% - 99.42%Couleur et forme :SolidMasse moléculaire :272.25Ref: TM-TJS1779
1mg87,00€5mg216,00€10mg354,00€25mg582,00€50mg825,00€100mg1.111,00€1mL*10mM (DMSO)197,00€Napabucasin
CAS :Napabucasin (BBI608) is an orally available Stat3 and Y cell stemness inhibitor.Formule :C14H8O4Degré de pureté :98.43% - 99.61%Couleur et forme :SolidMasse moléculaire :240.21CP21R7
CAS :CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.Formule :C19H15N3O2Degré de pureté :96.14% - 98.21%Couleur et forme :SolidMasse moléculaire :317.34Ref: TM-T3684
1mg63,00€2mg86,00€5mg97,00€10mg155,00€25mg273,00€50mg462,00€100mg677,00€1mL*10mM (DMSO)81,00€
