Wnt/beta-caténine
Les inhibiteurs de la voie Wnt/beta-caténine sont des composés qui ciblent et inhibent la voie de signalisation Wnt/beta-caténine, essentielle pour la régulation du développement embryonnaire, de la prolifération cellulaire et du maintien des cellules souches. La dérégulation de cette voie est liée à divers cancers et maladies dégénératives. Les inhibiteurs de la signalisation Wnt/beta-caténine sont précieux pour la recherche visant à comprendre le rôle de cette voie dans les maladies et à développer des thérapies ciblées. Chez CymitQuimica, nous proposons des inhibiteurs de Wnt/beta-caténine pour soutenir vos recherches en biologie des cellules souches, biologie du développement et recherche sur le cancer.
Produits appartenant à la catégorie "Wnt/beta-caténine"
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81 produits dans cette catégorie.
BML-284 hydrochloride
CAS :BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.Formule :C19H19ClN4O3Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :386.84Ref: TM-T8820
1mg35,00€5mg67,00€10mg88,00€25mg150,00€50mg266,00€100mg462,00€200mg648,00€500mg1.017,00€1mL*10mM (DMSO)89,00€Wnt-C59
CAS :Wnt-C59 (C59)(C59) is a highly effective and specific Wnt signaling antagonis with PORCN enzymatic activity.Formule :C25H21N3ODegré de pureté :99.56% - 99.95%Couleur et forme :SolidMasse moléculaire :379.45TNIK-IN-2
CAS :TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.Formule :C22H19N3O3Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :373.4Hematein
CAS :Hematein blocks Akt/PKB, Wnt signaling, promotes apoptosis in lung cancer, is a dye from hematoxylin, and inhibits casein kinase II (IC50: 0.74 μM).Formule :C16H12O6Degré de pureté :98%Couleur et forme :Dark Brown Crystalline PowderMasse moléculaire :300.26ABC99
CAS :ABC99 irreversibly inhibits wnt-deacylating enzyme NOTUM (IC50: 13 nM) with high serine hydrolase family selectivity.Formule :C22H21ClN4O5Degré de pureté :98.65%Couleur et forme :SoildMasse moléculaire :456.88Ref: TM-T23602
1mg172,00€5mg354,00€10mg528,00€25mg852,00€50mg1.159,00€100mg1.568,00€1mL*10mM (DMSO)354,00€Tabituximab
CAS :BMS-986148 is a CHO-expressed humanized antibody-drug coupling targeting mesothelin-expressing cells for cytotoxic load delivery.Couleur et forme :LiquidMasse moléculaire :145.5 kDaHLY78
CAS :HLY78, a Wnt/β-catenin activator, enhances Axin-LRP6 binding by targeting Axin's DIX domain.Formule :C17H17NO2Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :267.32JW 67
CAS :JW 67 is an inhibitor of canonical Wnt pathway signaling.Formule :C21H18N2O6Degré de pureté :97.02%Couleur et forme :SolidMasse moléculaire :394.38Ref: TM-T22884
1mg46,00€2mg59,00€5mg87,00€10mg137,00€25mg273,00€50mg439,00€100mg647,00€1mL*10mM (DMSO)97,00€IWP-3
CAS :IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1γ3 and CK1ε, but does not inhibit CK1α [1] [2].Formule :C22H17FN4O2S3Degré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :484.59Teplinovivint
CAS :Teplinovivint is a potent inhibitor of the Wnt/β-catenin signaling pathway, demonstrating anti-inflammatory properties with potential utility in tendinopathyFormule :C25H26N6O2Degré de pureté :97.21%Couleur et forme :SolidMasse moléculaire :442.51TNIK-IN-5
CAS :TNIK-IN-5: strong TNIK inhibitor (IC50=0.05μM), halts Wnt signaling, effective against colorectal cancer in vitro.Formule :C22H17N3O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :371.39FH535
CAS :FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.Formule :C13H10Cl2N2O4SDegré de pureté :98.25% - 99.5%Couleur et forme :SolidMasse moléculaire :361.2Ref: TM-T2413
5mg38,00€10mg57,00€25mg94,00€50mg164,00€100mg274,00€200mg404,00€500mg653,00€1mL*10mM (DMSO)64,00€Miclxin
CAS :Miclxin (DS37262926) is a novel MIC60 inhibitor that induces apoptosis through mitochondrial stress in mutant tumor cells via β-catenin.Miclxin is a potentFormule :C26H27N5O2Degré de pureté :100% - 99.57%Couleur et forme :SolidMasse moléculaire :441.52Ref: TM-T73415
1mg64,00€5mg140,00€10mg192,00€25mg324,00€50mg452,00€100mg620,00€200mg835,00€1mL*10mM (DMSO)156,00€FzM1
CAS :FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2)Formule :C21H16N2O2SDegré de pureté :99.37% - 99.89%Couleur et forme :SolidMasse moléculaire :360.43Ref: TM-T24076
1mg42,00€5mg64,00€10mg99,00€25mg188,00€50mg328,00€100mg528,00€500mg1.130,00€1mL*10mM (DMSO)62,00€Toxoflavin
CAS :Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex. Toxoflavin also acts as an inhibitor of KDM4A.Formule :C7H7N5O2Degré de pureté :98.24% - 99.7%Couleur et forme :SolidMasse moléculaire :193.16Wnt/β-catenin agonist 3
CAS :Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist.Formule :C16H15ClN4O2Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :330.77Ref: TM-T9988
5mg74,00€10mg107,00€25mg216,00€50mg354,00€100mg567,00€200mg800,00€500mg1.198,00€1mL*10mM (DMSO)81,00€PRI-724
CAS :PRI-724 is a second-generation, selective small molecule inhibitor of the β-catenin/CBP interaction.Cost-effective and quality-assured.Formule :C33H35N6O7PDegré de pureté :98.25% - 99.11%Couleur et forme :SoildMasse moléculaire :658.641(R),2(S)-epoxy Cannabidiol
CAS :1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analog of phytocannabinoids, exhibiting significant inhibitory activity on the Wnt/β-catenin pathway. It holds potential for research as a neuroprotective agent.Formule :C21H30O3Couleur et forme :SolidMasse moléculaire :330.46Wnt/β-catenin agonist 4
CAS :Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.Formule :C16H15FN4O2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :314.31Ref: TM-T60803
1mg35,00€5mg70,00€10mg103,00€25mg182,00€50mg311,00€100mg512,00€200mg720,00€1mL*10mM (DMSO)81,00€IWR-1
CAS :IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).Formule :C25H19N3O3Degré de pureté :98.46% - 99.82%Couleur et forme :SolidMasse moléculaire :409.44WIC1
CAS :2H-1-Benzopyran-3-carboxamide, N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo- is a compound that is potential for the treatment of tumours.Formule :C22H23N3O3Degré de pureté :99.57%Couleur et forme :SoildMasse moléculaire :377.44F7H
CAS :F7H is an FZD7 antagonist, a potent ligand for the FZD7 transmembrane domain (TMD), with potential antitumor and bacteriostatic activities.Formule :C24H18FN3O2S2Degré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :463.55NRX-103094
CAS :NRX-103094 boosts β-catenin binding to SCFβ-TrCP ligase with EC50 62 nM and Kd 0.6 nM.Formule :C20H11Cl2F3N2O4SDegré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :503.28Gossypolone
CAS :Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.Formule :C30H26O10Degré de pureté :96.66%Couleur et forme :SolidMasse moléculaire :546.52TNKS-2-IN-2
CAS :TNKS-2-IN-2 is a TNKS2 selective inhibitor (IC50: 22 nM) with potential anti-tumour activity for the study of colon cancer lung cancer and breast cancer.Formule :C26H23N3O6Degré de pureté :99.45%Couleur et forme :SoildMasse moléculaire :473.48KYA1797K
CAS :KYA1797K is a highly potent and selective inhibitor. Wnt/β-catenin IC50 is 0.75 μM through TOPflash assay.Formule :C17H11N2O6S2·KDegré de pureté :97.57% - 99.33%Couleur et forme :SolidMasse moléculaire :442.51N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
CAS :Macamide Impurity 14 promotes bone growth by activating Wnt/β-catenin, aiding osteoporosis study.Formule :C26H39NO2Degré de pureté :98.66%Couleur et forme :SolidMasse moléculaire :397.59TNIK-IN-3
CAS :TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).Formule :C23H18FN3O2Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :387.41Ref: TM-T9556
1mg106,00€5mg259,00€10mg406,00€25mg652,00€50mg938,00€100mg1.454,00€1mL*10mM (DMSO)284,00€ZW4864 free base
CAS :ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.Formule :C33H42N6O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :570.72Ref: TM-T9642
1mg160,00€5mg393,00€10mg587,00€25mg935,00€50mg1.264,00€100mg1.700,00€500mg3.410,00€1mL*10mM (DMSO)432,00€iCRT 14
CAS :iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).Formule :C21H17N3O2SDegré de pureté :98.85% - 99.8%Couleur et forme :SolidMasse moléculaire :375.44IQ 1
CAS :IQ 1 has multiple roles, such as maintaining the multifunctionality of mouse ESCs, decreasing Wnt-stimulated phosphorylation, blocking PP2A/Nkd interactions.Formule :C21H22N4O2Degré de pureté :98.57% - ≥95%Couleur et forme :SolidMasse moléculaire :362.42Ref: TM-T3635
5mg51,00€10mg78,00€25mg140,00€50mg195,00€100mg350,00€200mg500,00€500mg810,00€1mL*10mM (DMSO)57,00€CDK8-IN-11
CAS :CDK8-IN-11 is a CDK8 inhibitor that demonstrates anti-proliferative activity against colon cancer cell lines and inhibits the activation of WNT/β-catenin.Formule :C19H15F3N4O2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :388.34Ref: TM-T61742
1mg59,00€5mg127,00€10mg205,00€25mg454,00€50mg748,00€100mg1.054,00€200mg1.415,00€1mL*10mM (DMSO)139,00€YW2036
CAS :YW2036 is an inhibitor of Wnt signaling pathway.Formule :C20H16N4ODegré de pureté :100%Couleur et forme :SoildMasse moléculaire :328.37LF3
CAS :LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 (IC50 < 2 μM)Formule :C20H24N4O2S2Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :416.56SRI 37892
CAS :SRI 37892 is a Fzd7 inhibitor with potent activities against Wnt/β-catenin signaling and cancer cell viability.Formule :C26H19N5O2SDegré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :465.53Ref: TM-T9662
1mg378,00€5mg922,00€10mg1.225,00€25mg1.853,00€50mg2.490,00€100mg3.353,00€1mL*10mM (DMSO)1.074,00€FzM1.8
CAS :FzM1.8: allosteric FZD4 agonist, pEC50=6.4; boosts TCF/LEF, activates WNT/β-catenin with no WNT needed.Formule :C18H14N2O4Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :322.31Ref: TM-T15363
2mg42,00€5mg60,00€10mg96,00€25mg177,00€50mg283,00€100mg454,00€200mg653,00€1mL*10mM (DMSO)95,00€Neurodazine
CAS :Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.Formule :C27H21ClN2O3Degré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :456.92Carboxylesterase-IN-3
CAS :Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.Formule :C11H6Cl2N4OSDegré de pureté :97.49% - 97.89%Couleur et forme :SolidMasse moléculaire :313.16Nefopam hydrochloride
CAS :Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Formule :C17H20ClNODegré de pureté :99.32% - 99.85%Couleur et forme :SolidMasse moléculaire :289.8TINK-IN-1
CAS :TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.Formule :C24H24N4O3Degré de pureté :99.4%Couleur et forme :SoildMasse moléculaire :416.47Ref: TM-T77660
1mg42,00€2mg52,00€5mg87,00€10mg127,00€25mg250,00€50mg373,00€100mg547,00€500mg1.159,00€Pyrvinium pamoate
CAS :Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drugFormule :C26H28N3C23H14O6Degré de pureté :100% - 98.43%Couleur et forme :SolidMasse moléculaire :575.71β-catenin-IN-2
CAS :β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.Formule :C15H14FN3Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :255.29Ref: TM-T9696
1mg96,00€5mg227,00€10mg359,00€25mg607,00€50mg868,00€100mg1.169,00€500mg2.365,00€1mL*10mM (DMSO)264,00€KY02111
CAS :KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.Formule :C18H17ClN2O3SDegré de pureté :97.71%（96.56%） - 98.68%Couleur et forme :SolidMasse moléculaire :376.86Tegatrabetan
CAS :Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.Formule :C28H36N4O6S2Degré de pureté :98.01% - 99.18%Couleur et forme :SolidMasse moléculaire :588.74Ref: TM-T5642
1mg40,00€2mg52,00€5mg85,00€10mg124,00€25mg210,00€50mg334,00€100mg565,00€1mL*10mM (DMSO)96,00€CWP232228
CAS :CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.Formule :C33H34N7Na2O7PDegré de pureté :96.13%Couleur et forme :SolidMasse moléculaire :717.63Cardiogenol C
CAS :Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.Formule :C13H16N4O2Degré de pureté :98.46%Couleur et forme :SolidMasse moléculaire :260.29EMT inhibitor-1
CAS :EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.Formule :C12H12Cl2N2O2SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :319.21Ref: TM-T11190
1mg111,00€5mg264,00€10mg424,00€25mg723,00€50mg1.008,00€100mg1.378,00€500mg2.737,00€1mL*10mM (DMSO)283,00€exo-IWR-1
CAS :exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-cateninFormule :C25H19N3O3Degré de pureté :97.41%Couleur et forme :SolidMasse moléculaire :409.44Ref: TM-T22775
5mg34,00€10mg52,00€25mg105,00€50mg173,00€100mg279,00€200mg406,00€1mL*10mM (DMSO)44,00€Vantictumab
CAS :Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.Couleur et forme :Liquidβ-catenin/CBP-IN-1
CAS :β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-cateninFormule :C33H35N6O7PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :658.64Ipafricept
CAS :Ipafricept (OMP-54F28) is a recombinant fusion protein and Wnt inhibitor that blocks Wnt signaling.Couleur et forme :LiquidSKL2001
CAS :SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction.Formule :C14H14N4O3Degré de pureté :97.46% - 99.5%Couleur et forme :SolidMasse moléculaire :286.29Ref: TM-T6989
5mg40,00€10mg60,00€25mg107,00€50mg185,00€100mg339,00€200mg510,00€500mg797,00€1mL*10mM (DMSO)66,00€KY1220
CAS :KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.Formule :C14H10N4O3SDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :314.32Ref: TM-T15677
2mg46,00€5mg80,00€10mg117,00€25mg259,00€50mg374,00€100mg545,00€200mg740,00€1mL*10mM (DMSO)73,00€NRX-252262
CAS :NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50:3.8 nM)Formule :C23H17Cl2F3N2O4SDegré de pureté :99.10% - 99.87%Couleur et forme :SolidMasse moléculaire :545.36Ref: TM-T9182
1mg114,00€5mg273,00€10mg432,00€25mg715,00€50mg1.008,00€100mg1.359,00€1mL*10mM (DMSO)329,00€MSAB
CAS :MSAB inhibits Wnt/β-catenin by binding to β-catenin and inducing its breakdown.Formule :C15H15NO4SDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :305.35Ref: TM-T8710
1mg37,00€2mg49,00€5mg73,00€10mg119,00€25mg235,00€50mg354,00€100mg535,00€500mg1.121,00€1mL*10mM (DMSO)82,00€LP-922056
CAS :LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.Formule :C11H9ClN2O2S2Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :300.78DK419
CAS :DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.Formule :C16H8ClF6N3ODegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :407.7NRX-252114
CAS :NRX-252114 promotes mutant β-catenin degradation, binding it to E3 ligase SCFβ-TrCP (EC50: 6.5 nM; Kd: 0.4 nM).Formule :C22H12Cl2F3N3O2SDegré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :510.32Dendrobium phenol
CAS :Gigantol is a novel inhibitor of the Wnt/β-catenin pathway.Formule :C16H18O4Degré de pureté :98.66% - 99.48%Couleur et forme :SolidMasse moléculaire :274.31Ref: TM-TL0008
1mg49,00€2mg65,00€5mg97,00€10mg156,00€25mg255,00€50mg373,00€100mg555,00€1mL*10mM (DMSO)165,00€Pamidronic acid
CAS :Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem CellsFormule :C3H11NO7P2Degré de pureté :97.72%Couleur et forme :SolidMasse moléculaire :235.07Wnt pathway activator 2
CAS :Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.Formule :C17H15NO4Degré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :297.31Ref: TM-T13345
1mg49,00€5mg105,00€10mg169,00€25mg344,00€50mg562,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)116,00€JW74
CAS :JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).Formule :C24H20N6O2SDegré de pureté :95.00%Couleur et forme :SolidMasse moléculaire :456.52BML-284
CAS :BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.Formule :C19H18N4O3Degré de pureté :99.66% - 99.91%Couleur et forme :SolidMasse moléculaire :350.37Ref: TM-T3144
5mg60,00€10mg88,00€25mg140,00€50mg253,00€100mg427,00€200mg615,00€500mg938,00€1mL*10mM (DMSO)66,00€WAY-262611
CAS :WAY262611 is a Wnt/β-catenin agonist and an inhibitor of Dkk1. It increases bone formation rate with EC50 of 0.63 μM in TCF-luciferase assay.Formule :C20H22N4Degré de pureté :98.09% - 99.09%Couleur et forme :SolidMasse moléculaire :318.42Adavivint
CAS :Adavivint (Adavivint (SM04690)) (SM04690) is a Wnt pathway inhibitor.Formule :C29H24FN7ODegré de pureté :98.27% - 98.6%Couleur et forme :SolidMasse moléculaire :505.55CCT 031374 hydrobromide
CAS :CCT 031374 hydrobromide is a TCF/β-catenin inhibitor with antitumor activities.Formule :C23H20BrN3ODegré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :434.33Ref: TM-T21685
1mg38,00€5mg71,00€10mg105,00€25mg207,00€50mg329,00€100mg472,00€200mg620,00€1mL*10mM (DMSO)87,00€IWP-4
CAS :IWP-4 (Inhibitor of Wnt Production-4) is a potent Wnt inhibitor.Formule :C23H20N4O3S3Degré de pureté :100.00%Couleur et forme :SolidMasse moléculaire :496.62Cardiogenol C hydrochloride
CAS :Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).Formule :C13H17ClN4O2Degré de pureté :99.89% - 99.94%Couleur et forme :SolidMasse moléculaire :296.75TNIK-IN-7
CAS :TNIK-IN-7 is a Traf2 and Nck interacting kinase (TNIK) inhibitor with antitumor activity for the study of signaling and proliferation in colorectal cancer cellsFormule :C23H22N4O2Degré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :386.45Tankyrase-IN-2
CAS :Tankyrase-IN-2 is a selective, potent and orally active inhibitor of tankyrase with IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectivelyFormule :C17H14F2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :316.3BML-286
CAS :BML-286 is a WNT pathway modulator with potential anticancer activity and induces β-catenin- and TCF- dependent transcriptional activity.Formule :C22H18N2O4Couleur et forme :SolidMasse moléculaire :374.39Carboxylesterase-IN-2
CAS :Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.Formule :C13H12N4OSDegré de pureté :100%Couleur et forme :SoildMasse moléculaire :272.33Ref: TM-T77524
1mg62,00€5mg140,00€10mg215,00€25mg369,00€50mg509,00€100mg702,00€200mg944,00€1mL*10mM (DMSO)156,00€IWP-O1
CAS :IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.Formule :C26H20N6ODegré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :432.48Ref: TM-T5342
2mg39,00€5mg64,00€10mg101,00€25mg163,00€50mg226,00€100mg320,00€200mg459,00€1mL*10mM (DMSO)70,00€Wnt pathway inhibitor 3
CAS :Wnt pathway inhibitor 3 is a potent AC1 inhibitor with an IC50 value of 45 nM.Wnt pathway inhibitor 3 has antiproliferative activity and can be used in studiesFormule :C21H17BrN2O5Degré de pureté :99.69%Couleur et forme :SoildMasse moléculaire :457.27NRX-103095
CAS :NRX-103095 increases β-catenin binding to SCFβ-TrCP E3 ligase; EC50 is 163 nM for pSer33/Ser37 affinity boost.Formule :C22H16Cl2F3N3O3SDegré de pureté :99.16% - 99.60%Couleur et forme :SolidMasse moléculaire :530.35Ref: TM-T63730
1mg150,00€5mg364,00€10mg588,00€25mg1.169,00€50mg1.882,00€100mg2.822,00€1mL*10mM (DMSO)426,00€KY-05009
CAS :KY-05009 blocks TGF-β1 EMT in lung cancer cells, inhibits TNIK, Wnt genes, induces apoptosis, and is an ATP-competitive TNIK inhibitor (Ki = 100 nM).Formule :C18H16N4O2SDegré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :352.41Ref: TM-T11793
5mg50,00€10mg71,00€25mg117,00€50mg170,00€100mg245,00€200mg354,00€1mL*10mM (DMSO)51,00€CCT251545
CAS :CCT251545 is an potent and oral-bioavailable WNT signaling inhibitor(IC50 of 5 nM in 7dF3 cells).Formule :C23H24ClN5ODegré de pureté :98.2% - 98.69%Couleur et forme :SolidMasse moléculaire :421.92β-catenin modulator IIa-661
CAS :β-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity.Formule :C19H23ClN2O3SDegré de pureté :99.53%Couleur et forme :SoildMasse moléculaire :394.92ETC-159
CAS :ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM.Formule :C19H17N7O3Degré de pureté :96.87% - 99.30%Couleur et forme :SolidMasse moléculaire :391.38Wnt pathway activator 1
CAS :Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM.Formule :C18H16O4Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :296.32Ref: TM-T17256
2mg34,00€5mg52,00€10mg80,00€25mg131,00€50mg212,00€100mg316,00€200mg454,00€1mL*10mM (DMSO)52,00€Blosozumab
CAS :Blosozumab (LY2541546) is a monoclonal antibody targeting sclerostin that promotes bone formation, used in the research of osteoporosis.Degré de pureté :>95% - >95%Couleur et forme :Liquid
