Cellules souches
Les inhibiteurs de cellules souches sont des composés qui ciblent spécifiquement les cellules souches et leurs voies de signalisation, affectant leur capacité à s'auto-renouveler et à se différencier. Ces inhibiteurs sont essentiels dans la recherche axée sur le contrôle du comportement des cellules souches, la compréhension des processus de développement et le développement de thérapies pour des maladies comme le cancer, où les cellules souches sont censées jouer un rôle clé. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de cellules souches pour soutenir vos recherches en médecine régénérative, biologie du développement et oncologie.
Produits appartenant à la catégorie "Cellules souches"
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AS 1892802
CAS :AS 1892802, a ROCK inhibitor: IC50 - 52nM (hROCK2), 57nM (rROCK2), 122nM (hROCK1). Fast antinociceptive effect similar to Tramadol, Diclofenac.Formule :C20H19N3O2Degré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :333.38Ref: TM-T22037
1mg52,00€5mg97,00€10mg170,00€25mg378,00€50mg560,00€100mg800,00€200mg1.103,00€1mL*10mM (DMSO)120,00€EMT inhibitor-1
CAS :EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.Formule :C12H12Cl2N2O2SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :319.21Ref: TM-T11190
1mg111,00€5mg264,00€10mg424,00€25mg723,00€50mg1.008,00€100mg1.378,00€500mg2.737,00€1mL*10mM (DMSO)283,00€JAK-IN-27
CAS :JAK-IN-27, also known as compound 1, is an orally active, potent inhibitor of the JAKS family kinases, displaying inhibitory concentrations (IC50s) of 3.0 nMFormule :C20H21F2N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :413.42Emugrobart
Emugrobart is a humanized IgG1κ antibody targeted at GDF8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Couleur et forme :Odour LiquidSAG dihydrochloride
CAS :SAG dihydrochloride: potent Smo agonist, activates Hedgehog pathway, counters Cyclopamine. EC50=3 nM, Kd=59 nM.Formule :C28H30Cl3N3OSDegré de pureté :100%Couleur et forme :SoildMasse moléculaire :562.984-Chloro-2'-bromoacetophenone
CAS :4-Chloro-2'-bromoacetophenone against glycogen synthase kinase-3 (GSK-3beta).Formule :C8H6BrClODegré de pureté :99.56%Couleur et forme :White To Beige SolidMasse moléculaire :233.49exo-IWR-1
CAS :exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-cateninFormule :C25H19N3O3Degré de pureté :97.41%Couleur et forme :SolidMasse moléculaire :409.44Ref: TM-T22775
5mg34,00€10mg52,00€25mg105,00€50mg173,00€100mg279,00€200mg406,00€1mL*10mM (DMSO)44,00€JAK2-IN-11
CAS :JAK2-IN-11 (Example 6) is a JAK2 kinase inhibitor with potent antitumor activity, exhibiting an IC50 of ≤10 nM against JH2 BIND WT/V617F. This compound effectively suppresses tumor growth.Formule :C31H31F3N8O4Couleur et forme :SolidMasse moléculaire :639.64ROCK2-IN-6 hydrochloride
CAS :ROCK2-IN-6 hydrochloride (Comp A)为一种选择性ROCK2抑制剂,适用于研究ROCK介导的疾病、自身免疫性病症与炎症。Formule :C26H22ClF2N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.95MRK-560
CAS :MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.Formule :C19H17ClF5NO4S2Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :517.92ABC1183
CAS :ABC1183, an oral diaminothiazole, inhibits GSK3α/β, CDK9, hinders cancer cell growth, induces G2/M arrest, and modulates phosphorylation.Formule :C18H14N4OSDegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :334.39Jagged-1 (188-204) TFA(219127-21-6 free base)
Jagged-1 (188-204) TFA, a JAG-1 skin protein fragment, induces epidermal maturation and keratinocyte stratification.Formule :C95H128F3N25O28S3Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :2221.37Foxy-5 acetate
Foxy-5 acetate: Wnt 5A agonist, inhibits cancer cell migration/invasion, boosts calcium signaling, doesn't activate β-catenin.Formule :C28H46N6O14S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :754.83TTP 22
CAS :TTP 22: ATP-competitive CK2 inhibitor; IC50/Ki: 0.1 μM/40 nM; >250x selective over JNK3, ROCK1, MET.Formule :C16H14N2O2S2Degré de pureté :97.08% - 97.78%Couleur et forme :SolidMasse moléculaire :330.42Lats-IN-1
CAS :Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.Formule :C18H14N4OSDegré de pureté :97.54% - 99.82%Couleur et forme :SolidMasse moléculaire :334.39Ref: TM-T9053
1mg73,00€5mg145,00€10mg220,00€25mg437,00€50mg567,00€100mg805,00€200mg1.111,00€1mL*10mM (DMSO)161,00€GSK-3β inhibitor 19
GSK-3β Inhibitor 19 (compound 36) is an inhibitor of GSK-3β with an IC50 value of 70 nM. It is applicable in research related to anti-inflammatory and Alzheimer's disease.Formule :C15H12N4O2SCouleur et forme :SolidMasse moléculaire :312.35Fasudil
CAS :Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Formule :C14H17N3O2SDegré de pureté :99.79% - 99.84%Couleur et forme :SolidMasse moléculaire :291.37SGC-CK2-1
CAS :SGC-CK2-1, a CK2 inhibitor, is a inducer of insulin production and secretion in pancreatic β-cells.Formule :C20H21N7ODegré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :375.43CK1-IN-2
CAS :CK1-IN-2 (compound Nr.4) is a potent inhibitor of CK1, exhibiting IC50 values of 123 nM for CK1a, 19.8 nM for CK1d, 26.8 nM for CK1e, and 74.3 nM for p38a [1].Formule :C17H12FN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :309.29TEAD-IN-2
CAS :TEAD-IN-2 is a potent and bifunctional TEAD inhibitor to induce TEAD protein degradation via the ubiquitination pathway, with anticancer potential.Formule :C16H18BrF3N2OCouleur et forme :SolidMasse moléculaire :391.23JAK1-IN-4
CAS :JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).Formule :C26H32FN9O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.59Cyclopamine
CAS :Cyclopamine (11-Deoxojervine), a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the group of steroidal jerveratrum alkaloids.Formule :C27H41NO2Degré de pureté :98.31% - 99.66%Couleur et forme :White Crystalline SolidMasse moléculaire :411.62BRD0209
CAS :BRD0209 is a highly selective and potent GSK3 inhibitor.Formule :C22H25N3ODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :347.45Casein kinase 1δ-IN-4
CAS :"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."Formule :C16H12N6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :320.37JAK2 Inhibitor V
CAS :JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.Formule :C23H24N2ODegré de pureté :96.69% - 99.15%Couleur et forme :SolidMasse moléculaire :344.45Ref: TM-T3042
2mg39,00€5mg57,00€10mg85,00€25mg157,00€50mg274,00€100mg505,00€500mg1.121,00€1mL*10mM (DMSO)63,00€5β-Cholanic acid
CAS :5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.Formule :C24H40O2Degré de pureté :99.89%Couleur et forme :SoildMasse moléculaire :360.57SB-772077B dihydrochloride
CAS :SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).Formule :C15H20Cl2N8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :415.28P17 Peptide
CAS :P17 Peptide, a human TGF-β1 inhibitory peptide, effectively blocks the activity of woodchuck TGF-β1.Formule :C95H139N27O21Couleur et forme :SolidMasse moléculaire :1995.29Vantictumab
CAS :Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.Couleur et forme :LiquidDemcizumab
CAS :Demcizumab (OMP 21M18), an anti-DLL4 antibody, inhibits the Notch pathway and fights various cancers solo or with chemo.Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :145.34 kDaDPP
CAS :DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstratingFormule :C36H40Cl2N2O10PtDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :926.7BMS-983970
CAS :BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.Formule :C26H26F4N4O3Couleur et forme :SolidMasse moléculaire :518.5Enoticumab
CAS :Enoticumab (REGN421) is a fully human IgG1 monoclonal antibody with anticancer activity that inhibits cancer cell growth.Couleur et forme :LiquidAJI-100
CAS :AJI-100 serves as a dual-target inhibitor, effectively blocking Aurora kinase A and JAK2, with respective IC50 values of 12.7 nM and 18.5 nM. It inhibits T cell mitosis and cell polarity by directly targeting Aurora kinase A and reduces STAT3 phosphorylation by inhibiting JAK2 activation, consequently diminishing the differentiation of TH1 and TH17 cells. This compound is utilized in researching immune response regulation and the prevention of graft-versus-host disease (GVHD).Formule :C17H14FN5OCouleur et forme :SolidMasse moléculaire :323.32TCS 21311
CAS :TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.Formule :C27H25F3N4O4Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :526.51CSNK2-IN-2
CSNK2-IN-2 (compound 2) is an orally active inhibitor of CSNK2. It is utilized in antiviral research.Formule :C25H30FN9OCouleur et forme :SolidMasse moléculaire :491.56Casein kinase 1δ-IN-3
CAS :Casein kinase 1δ-IN-3 (Casein kinase 1δ-IN-3) (Compound 23a) is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M.Formule :C17H16N2O2SDegré de pureté :99.42%Couleur et forme :SoildMasse moléculaire :312.39Ref: TM-T64350
1mg38,00€5mg73,00€10mg115,00€25mg235,00€50mg373,00€100mg560,00€200mg797,00€1mL*10mM (DMSO)87,00€H-1152 dihydrochloride
CAS :H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.Formule :C16H23Cl2N3O2SDegré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :392.34Ref: TM-T35328
1mg64,00€5mg142,00€10mg227,00€25mg439,00€50mg692,00€100mg938,00€1mL*10mM (DMSO)156,00€MSC-5046
MSC-5046 is a selective inhibitor of TEAD1.Formule :C24H18F3N5O3Couleur et forme :SolidMasse moléculaire :481.43WAY-297174
CAS :WAY-297174 is a human protein kinase CK2 inhibitor with IC50 of > 33 μM.Formule :C11H12N2O2S2Degré de pureté :99.43%Couleur et forme :SoildMasse moléculaire :268.36Ref: TM-T60067
1mg84,00€5mg163,00€10mg229,00€25mg379,00€50mg568,00€100mg810,00€500mg1.644,00€1mL*10mM (DMSO)155,00€SB 216763
CAS :SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).Formule :C19H12Cl2N2O2Degré de pureté :99.13% - 99.61%Couleur et forme :SolidMasse moléculaire :371.22Ref: TM-T3077
2mg39,00€5mg52,00€10mg79,00€25mg131,00€50mg197,00€100mg334,00€500mg803,00€1mL*10mM (DMSO)52,00€GSK-3β inhibitor 8
CAS :GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an IC50 value of 64 nM.GSK-3β inhibitor 8 is a thienopyrimidineFormule :C20H20ClN5OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :413.92Napabucasin
CAS :Napabucasin (BBI608) is an orally available Stat3 and Y cell stemness inhibitor.Formule :C14H8O4Degré de pureté :98.43% - 99.61%Couleur et forme :SolidMasse moléculaire :240.21CP21R7
CAS :CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.Formule :C19H15N3O2Degré de pureté :96.14% - 98.21%Couleur et forme :SolidMasse moléculaire :317.34Ref: TM-T3684
1mg63,00€2mg86,00€5mg97,00€10mg155,00€25mg273,00€50mg462,00€100mg677,00€1mL*10mM (DMSO)81,00€GSK3-IN-2
CAS :GSK3-IN-2 is a potent GSK3 inhibitor for the treatment of diabetes and neurodegenerative diseases.Formule :C17H19N3OSDegré de pureté :98.8%Couleur et forme :SolidMasse moléculaire :313.42Ciliobrevin A
CAS :Ciliobrevin A (HPI-4) is an inhibitor of hedgehog signaling pathway with an IC50 <10 μM.Formule :C17H9Cl2N3O2Degré de pureté :97.10% - 98.54%Couleur et forme :SolidMasse moléculaire :358.18Ref: TM-T3156
2mg42,00€5mg59,00€10mg85,00€25mg168,00€50mg235,00€100mg331,00€200mg492,00€1mL*10mM (DMSO)69,00€GNE-7883
CAS :GNE-7883 is an inhibitor targeting TEAD transcription factor, inhibits cell proliferation and suppresses YAP/TAZ activation, and can be used to study YAP/TAZ-dependent tumors.Formule :C28H29FN6O2Degré de pureté :97.61%Couleur et forme :SolidMasse moléculaire :500.57Ref: TM-T78558
1mg116,00€5mg283,00€10mg455,00€25mg747,00€50mg1.026,00€100mg1.444,00€200mg1.882,00€1mL*10mM (DMSO)310,00€Aβ-IN-1
CAS :Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM).Formule :C35H49NDegré de pureté :99.14%Couleur et forme :SoildMasse moléculaire :483.77Ipafricept
CAS :Ipafricept (OMP-54F28) is a recombinant fusion protein and Wnt inhibitor that blocks Wnt signaling.Couleur et forme :LiquidCMPD101
CAS :CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).Formule :C24H21F3N6ODegré de pureté :98.34% - 99.01%Couleur et forme :SolidMasse moléculaire :466.46JAK2-IN-9
CAS :Compound A8, known as JAK2-IN-9, is a selective JAK2 inhibitor with an IC50 of 5 nM.Formule :C20H24N6O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.51ROCK-IN-6
CAS :ROCK-IN-6, a selective ROCK2 inhibitor, exhibits potent inhibition with an IC50 of 2.19 nM and holds promise for research into glaucoma and retinal diseases [1Formule :C19H19N5O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.45Amcasertib
CAS :Amcasertib (BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases.Formule :C31H33N5O2SDegré de pureté :100% - 99.31%Couleur et forme :SolidMasse moléculaire :539.69Zelasudil
CAS :Zelasudil (RXC007) is a Rho-related (ROCK) kinase inhibitor for the study of idiopathic pulmonary fibrosis and inflammation.Formule :C22H21F2N7ODegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :437.445Ref: TM-T69665
1mg92,00€5mg180,00€10mg274,00€25mg469,00€50mg653,00€100mg912,00€200mg1.225,00€1mL*10mM (DMSO)188,00€A 1070722
CAS :A 1070722: potent GSK-3 inhibitor, Ki = 0.6 nM for both α/β isoforms, crosses BBB, potential brain GSK-3 PET radiotracer.Formule :C17H13F3N4O2Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :362.31Rho-Kinase-IN-1
CAS :Rho-Kinase-IN-1: ROCK inhibitor, Ki of 30.5 nM (ROCK1) & 3.9 nM (ROCK2), used in research for diseases linked to cell overgrowth and inflammation.Formule :C20H24N4SDegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :352.5Ref: TM-T12721
1mg74,00€5mg145,00€10mg215,00€25mg378,00€50mg530,00€100mg702,00€200mg944,00€1mL*10mM (DMSO)111,00€ROCK-IN-2
CAS :ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.Formule :C18H13ClF2N6ODegré de pureté :97.29%Couleur et forme :SolidMasse moléculaire :402.79Ref: TM-TQ0110
1mg114,00€5mg274,00€10mg439,00€25mg727,00€50mg1.017,00€100mg1.378,00€1mL*10mM (DMSO)373,00€SKL2001
CAS :SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction.Formule :C14H14N4O3Degré de pureté :97.46% - 99.5%Couleur et forme :SolidMasse moléculaire :286.29Ref: TM-T6989
5mg40,00€10mg60,00€25mg107,00€50mg185,00€100mg339,00€200mg510,00€500mg797,00€1mL*10mM (DMSO)66,00€HODHBt
CAS :HODHBt is a STAT5-SUMO protein-protein interaction inhibitor.Formule :C7H5N3O2Degré de pureté :99.45% - 99.95%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :163.13RKI-1447
CAS :RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.Formule :C16H14N4O2SDegré de pureté :98% - 99.73%Couleur et forme :SolidMasse moléculaire :326.37Ref: TM-T1898
5mg51,00€10mg87,00€25mg187,00€50mg311,00€100mg414,00€200mg520,00€500mg840,00€1mL*10mM (DMSO)57,00€BD750
CAS :BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM inFormule :C14H13N3OSDegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :271.34Ascochlorin
CAS :Ascochlorin, an isoprenoid antibiotic, inhibits STAT3 to combat tumors, induces apoptosis, and reduces inflammation.Formule :C23H29ClO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :404.93CUR61414 hydrochloride
CUR61414 hydrochloride: potent cell-permeable Hedgehog pathway inhibitor, IC50=100-200 nM, selectively targets Smo (Ki=44 nM), induces cancer cell apoptosis.Formule :C31H43ClN4O5Degré de pureté :95.22%Couleur et forme :SolidMasse moléculaire :587.15GSK-3 inhibitor 4
CAS :Orally active GSK-3 inhibitor 4 targets GSK-3α/β, CDK2/5 (IC50: 0.45-0.68 μM) and may aid in Alzheimer's research by lowering Tau protein.Formule :C22H15F2N5ODegré de pureté :98.77%Couleur et forme :SoildMasse moléculaire :403.38Ref: TM-T77341
1mg333,00€5mg922,00€10mg1.140,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg3.734,00€CB-103
CAS :CB-103 is a orally active inhibitor of notch signaling pathway, with anti-tumor activity.Formule :C15H18N2ODegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :242.32CHIR-99021
CAS :View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.Formule :C22H18Cl2N8Degré de pureté :97.94% - ≥95%Couleur et forme :SolidMasse moléculaire :465.34Ref: TM-T2310
2mg43,00€5mg64,00€10mg96,00€25mg160,00€50mg254,00€100mg404,00€200mg603,00€500mg938,00€1mL*10mM (DMSO)70,00€FLI-06
CAS :FLI-06 is a Notch signaling inhibitor (EC50: 2.3 μM).Formule :C25H30N2O5Degré de pureté :100% - ≥98%Couleur et forme :SolidMasse moléculaire :438.52Ref: TM-T3075
1mg35,00€2mg52,00€5mg74,00€10mg99,00€25mg172,00€50mg311,00€100mg542,00€500mg1.188,00€1mL*10mM (DMSO)82,00€JAK-IN-3
CAS :JAK-IN-3 is a potent JAK inhibitor that inhibits JAK3, JAK1, TYK2, and JAK2, and can be used for the study of immune system disorders.Formule :C18H20N4O3Degré de pureté :98.04% - 98.19%Couleur et forme :SolidMasse moléculaire :340.38Ref: TM-T11704
1mg133,00€2mg188,00€5mg321,00€10mg518,00€25mg1.035,00€50mg1.644,00€100mg2.680,00€200mg3.591,00€1mL*10mM (DMSO)354,00€ML115
CAS :ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.Formule :C15H15ClN2O4Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :322.74Ref: TM-T35544
1mg95,00€5mg227,00€10mg359,00€25mg630,00€50mg882,00€100mg1.188,00€200mg1.596,00€500mg2.357,00€1mL*10mM (DMSO)251,00€GSK3i XIII
CAS :GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.Formule :C18H19N5Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :305.38Ref: TM-T24111
1mg99,00€5mg195,00€10mg293,00€25mg494,00€50mg715,00€100mg1.008,00€500mg2.015,00€1mL*10mM (DMSO)216,00€STX-0119
CAS :STX-0119 is a selective, orally active STAT3 dimerization inhibitor. STX-0119 inhibits STAT3 transcription with an IC50 of 74 μM.Formule :C22H14N4O3Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :382.37Ref: TM-T60160
5mg64,00€10mg92,00€25mg177,00€50mg283,00€100mg425,00€500mgÀ demander1mL*10mM (DMSO)64,00€GSK-3β inhibitor 22
CAS :GSK-3β inhibitor22 (compound 20o) is a GSK-3β inhibitor with an IC50 of 3.1 nM, showing potential for Alzheimer's disease research.Formule :C18H12F3N3O2S2Couleur et forme :SolidMasse moléculaire :423.43LY900009
CAS :LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.Formule :C23H27N3O4Degré de pureté :97.07%Couleur et forme :SolidMasse moléculaire :409.48Ref: TM-T9015
1mg38,00€5mg85,00€10mg118,00€25mg207,00€50mg306,00€100mg444,00€200mg622,00€1mL*10mM (DMSO)93,00€MF-Human S100B(S100 Calcium Binding Protein B) ELISA Kit
This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human S100B. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for Human S100B. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human S100B, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Human S100B. You can calculate the concentration of Human S100B in the samples by comparing the OD of the samples to the standard curve.Momelotinib Mesylate
CAS :Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.Formule :C24H26N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.57LM-41
CAS :LM-41 is a TEAD binding agent with potential anticancer activity for the study of breast cancer.Formule :C19H14FNO2Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :307.32KY1220
CAS :KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.Formule :C14H10N4O3SDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :314.32Ref: TM-T15677
2mg46,00€5mg80,00€10mg117,00€25mg259,00€50mg374,00€100mg545,00€200mg740,00€1mL*10mM (DMSO)73,00€Mouse GDF10(GrowthDifferentiation Factor 10) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse GDF10. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse GDF10. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse GDF10, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse GDF10 in the samples is then determined by comparing the OD of the samples to the standard curve.Couleur et forme :Colourless TransparentliquidNRX-252262
CAS :NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50:3.8 nM)Formule :C23H17Cl2F3N2O4SDegré de pureté :99.10% - 99.87%Couleur et forme :SolidMasse moléculaire :545.36Ref: TM-T9182
1mg114,00€5mg273,00€10mg432,00€25mg715,00€50mg1.008,00€100mg1.359,00€1mL*10mM (DMSO)329,00€5-Iodo-indirubin-3'-monoxime
CAS :5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50sFormule :C16H10IN3O2Couleur et forme :SolidMasse moléculaire :403.17Y-27632
CAS :Y-27632 (Y-27632) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II.Formule :C14H21N3ODegré de pureté :99.53% - 99.87%Couleur et forme :SolidMasse moléculaire :247.34Ref: TM-T1870
5mg47,00€10mg60,00€25mg97,00€50mg169,00€100mg274,00€200mg425,00€500mg702,00€1mL*10mM (DMSO)50,00€SAR407899
CAS :SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.Formule :C14H16N2O2Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :244.29MSAB
CAS :MSAB inhibits Wnt/β-catenin by binding to β-catenin and inducing its breakdown.Formule :C15H15NO4SDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :305.35Ref: TM-T8710
1mg37,00€2mg49,00€5mg73,00€10mg119,00€25mg235,00€50mg354,00€100mg535,00€500mg1.121,00€1mL*10mM (DMSO)82,00€ROCK-IN-1
CAS :ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurologicalFormule :C20H18FN3ODegré de pureté :100%Couleur et forme :SolidMasse moléculaire :335.37CK2 inhibitor 2
CAS :CK2 Inhibitor 2, characterized as a potent, selective, and orally active inhibitor of CK2, demonstrates an impressive IC50 value of 0.66 nM.Formule :C21H17ClN4O2Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :392.84Ref: TM-T35557
1mg65,00€5mg145,00€10mg226,00€25mg449,00€50mg672,00€100mg900,00€200mg1.216,00€1mL*10mM (DMSO)160,00€TGFβ-IN-5
CAS :TGFβ-IN-5 (WAY-641966) is a potent TGFβ inhibitor with anti-prion activity for the study of fibroproliferative diseases associated with TGF-β signaling.Formule :C20H16N4Degré de pureté :99.29% - 99.5%Couleur et forme :SolidMasse moléculaire :312.37STAT3-IN-35
CAS :STAT3-IN-35 is a STAT3 inhibitor that binds to the SH2 domain. This compound inhibits the phosphorylation of STAT3 and exhibits antiproliferative activity in triple-negative breast cancer (TNBC) cell lines. Additionally, STAT3-IN-35 has demonstrated toxicity and potent antitumor activity in TNBC xenograft models.Formule :C21H23NO4Couleur et forme :SolidMasse moléculaire :353.41Casein kinase 1δ-IN-10
CAS :Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).Formule :C21H17N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :359.38MF-Rat cTnT/TNNT2(Troponin T Type 2, Cardiac) ELISA Kit
This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat cTnT/TNNT2. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for Rat cTnT/TNNT2. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat cTnT/TNNT2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Rat cTnT/TNNT2. You can calculate the concentration of Rat cTnT/TNNT2 in the samples by comparing the OD of the samples to the standard curve.GSK429286A
CAS :GSK429286A (RHO-15) is a specific inhibitor of ROCK1/2 (IC50: 14/63 nM).Formule :C21H16F4N4O2Degré de pureté :97.68% - 98.42%Couleur et forme :SolidMasse moléculaire :432.37GSK-3 Inhibitor 5
CAS :4-Cyanophenacyl bromide, a ketone, used in drug-making and organic synthesis, blocks GSK-3.Formule :C9H6BrNODegré de pureté :99.58%Couleur et forme :Off-White To Light Yellow Crystalline PowderMasse moléculaire :224.05CP-352664
CAS :CP-352664 is a JAK inhibitor with potency against JAK3, exhibiting an EC50 value of 210 nM. It holds potential for use in research related to organ transplant rejection and autoimmune diseases, such as rheumatoid arthritis.Formule :C18H18N4Couleur et forme :SolidMasse moléculaire :290.36LP-922056
CAS :LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.Formule :C11H9ClN2O2S2Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :300.78PF-5274857
CAS :PF-5274857: selective hedgehog pathway inhibitor (IC50: 5.8 nM, Ki: 4.6 nM), treats brain tumors, crosses blood-brain barrier, orally stable.Formule :C20H25ClN4O3SDegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :436.96CK1-IN-3
CAS :WAY-296817 inhibits CK1, potential for circadian rhythm and inflammation research.Formule :C17H16N2O3SDegré de pureté :98.70%Couleur et forme :SolidMasse moléculaire :328.39Ref: TM-T60005
1mg48,00€5mg97,00€10mg145,00€25mg255,00€50mg368,00€100mg505,00€200mg692,00€1mL*10mM (DMSO)105,00€Mouse CC17(Clara Cell Protein) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse CC17. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse CC17. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse CC17, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse CC17 in the samples is then determined by comparing the OD of the samples to the standard curve.Couleur et forme :Colourless TransparentliquidKaempferol 3-neohesperidoside
CAS :Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside), a flavonoid compound, demonstrates an insulinomimetic effect on the rat soleus muscle.Formule :C27H30O15Degré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :594.52Ref: TM-TN1819
1mg62,00€5mg127,00€10mg187,00€25mg315,00€50mg472,00€100mg658,00€1mL*10mM (DMSO)166,00€GSK3-IN-4
CAS :GSK3-IN-4 is a GSK-3 inhibitor with IC50 of 0.101-1 μM of GSK-3α and GSK-3β in Calipe Assay.Formule :C18H20N4ODegré de pureté :97.1%Couleur et forme :SoildMasse moléculaire :308.38Ref: TM-T64366
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg472,00€100mg645,00€200mg868,00€1mL*10mM (DMSO)153,00€CKI-7 free base
CAS :CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Formule :C11H12ClN3O2SCouleur et forme :SolidMasse moléculaire :285.75GSK-3β inhibitor 20
CAS :GSK-3β inhibitor20 (compound 3A) is an effective inhibitor of GSK-3β, exhibiting an IC50 value of 74.4 nM.Formule :C22H21N5O2SCouleur et forme :SolidMasse moléculaire :419.50PF-5006739
CAS :PF-5006739: potent, selective CK1δ/ε inhibitor (IC50: 3.9/17.0 nM); may treat psychiatric disorders, improves glucose tolerance, reduces opioid seeking.Formule :C22H22FN7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.45GSK-3β inhibitor 12
CAS :GSK-3β inhibitor 12 is a selective GSK-3β inhibitor.GSK-3β inhibitor 12 inhibits 49.11% of 25 μM GSK-3β activity and 37.11% of 50 μM GSK-3β activity.GSK-3βFormule :C14H13N3OSDegré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :271.34K 00546
CAS :K00546 inhibits CDK1/cyclin B (IC50: 0.6 nM), CDK2/cyclin A (IC50: 0.5 nM), CLK1 (IC50: 8.9 nM), and CLK3 (IC50: 29.2 nM).Formule :C15H13F2N7O2S2Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :425.44ALLO-2
CAS :ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.Formule :C18H12F3N5ODegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :371.32Ref: TM-T14188
1mg64,00€5mg140,00€10mg212,00€25mg353,00€50mg500,00€100mg658,00€200mg905,00€1mL*10mM (DMSO)156,00€GSK-3β inhibitor 2
CAS :GSK-3β inhibitor 2 (5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy-) is a BBB-crossing and selective inhibitor of GSK-3β (IC50Formule :C14H14N4O3SDegré de pureté :95.69%Couleur et forme :SolidMasse moléculaire :318.35DK419
CAS :DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.Formule :C16H8ClF6N3ODegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :407.7STAT3-IN-13
CAS :STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.Formule :C21H20N6O3SDegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :436.49Stafib-2
CAS :Stafib-2 is a potent and selective inhibitor of the transcription factor STAT5b.Stafib-2 inhibits STAT5b and STAT5a with IC50 values of 82 nM and 1.7 μM,Formule :C28H26N2O12P2Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :644.46Ref: TM-T9646
1mg208,00€5mg518,00€10mg740,00€25mg1.093,00€50mg1.473,00€100mg2.015,00€1mL*10mM (DMSO)737,00€TED-347
CAS :TED-347 is an irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.Formule :C15H11ClF3NODegré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :313.7Tyk2-IN-20
CAS :Tyk2-IN-20 (Example 289) is an effective inhibitor of Tyk2 with an IC50 value below 5 nM. Additionally, it inhibits JAK1, JAK2, and JAK3 with IC50 values under 100 nM. This compound is utilized for the research of inflammatory diseases.Formule :C24H25N7O2Couleur et forme :SolidMasse moléculaire :443.50RBPJ Inhibitor-1
CAS :RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cellFormule :C17H14FN3O2Degré de pureté :99.58%Couleur et forme :SoildMasse moléculaire :311.31Ref: TM-T35566
1mg40,00€2mg52,00€5mg88,00€10mg137,00€25mg227,00€50mg393,00€100mg567,00€1mL*10mM (DMSO)87,00€MM-589 TFA
CAS :MM-589 TFA is a potent WD repeat domain 5 (WDR5)inhibitor and mixed lineage leukemia (MLL) protein-protein interaction.Formule :C30H45F3N8O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :686.72NRX-252114
CAS :NRX-252114 promotes mutant β-catenin degradation, binding it to E3 ligase SCFβ-TrCP (EC50: 6.5 nM; Kd: 0.4 nM).Formule :C22H12Cl2F3N3O2SDegré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :510.32Dendrobium phenol
CAS :Gigantol is a novel inhibitor of the Wnt/β-catenin pathway.Formule :C16H18O4Degré de pureté :98.66% - 99.48%Couleur et forme :SolidMasse moléculaire :274.31Ref: TM-TL0008
1mg49,00€2mg65,00€5mg97,00€10mg156,00€25mg255,00€50mg373,00€100mg555,00€1mL*10mM (DMSO)165,00€SJ000063181
CAS :SJ000063181 activates BMP signaling (EC50 ≤1μM), usable as probe in zebrafish embryos.Formule :C14H14ClFN2O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :296.72Ref: TM-T60644
1mg52,00€5mg97,00€10mg149,00€25mg283,00€50mg550,00€100mg792,00€500mg1.605,00€1mL*10mM (DMSO)96,00€3F8
CAS :3F8 is a selective GSK-3β inhibitor that can be used as a new tool and potential therapeutic candidate compound for GSK3-related diseases, and can be used inFormule :C15H14N2O4Degré de pureté :98.05% - 98.49%Couleur et forme :SolidMasse moléculaire :286.28Pamidronic acid
CAS :Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem CellsFormule :C3H11NO7P2Degré de pureté :97.72%Couleur et forme :SolidMasse moléculaire :235.07Hydroxyfasudil Hydrochloride
CAS :Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).Formule :C14H18ClN3O3SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :343.83DCN1-IN-2
CAS :DCN1-IN-2, a DCN1 inhibitor, exhibits potent activity with an IC 50 of 2.96 nM. It effectively mitigates Ang II/TGFβ-induced activation of cardiac fibroblasts and diminishes ISO-induced cardiac fibrosis and remodeling in mice through the selective inhibition of cullin 3.Formule :C18H14ClF3N4OSCouleur et forme :SolidMasse moléculaire :426.84KT-333
CAS :KT-333 is a potent, highly selective, heterobifunctional degrader of STAT3 for the treatment of a variety of STAT3-dependent pathologies, antitumor.Formule :C60H74ClN10O14PSDegré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :1257.78ROCK2-IN-6
CAS :ROCK2-IN-6 (Comp A) is a selective inhibitor of ROCK2, applicable in the study and treatment of ROCK-mediated, autoimmune, and inflammatory diseases [1].Formule :C26H21F2N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :485.49IWP L6
CAS :IWP L6 (Porcn Inhibitor III) is an extremely effective Porcn inhibitor (EC50: 0.5 nM).Formule :C25H20N4O2S2Degré de pureté :100% - 99.74%Couleur et forme :SolidMasse moléculaire :472.58HhAntag
CAS :HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway with the anti-tumor activityFormule :C24H23ClN4O3Degré de pureté :95.73%Couleur et forme :SolidMasse moléculaire :450.92Ref: TM-T3460
1mg52,00€5mg97,00€10mg178,00€25mg379,00€50mg645,00€100mg1.026,00€1mL*10mM (DMSO)110,00€AJI-214
CAS :AJI-214 functions as a dual-target inhibitor that specifically blocks Aurora kinase A and JAK2. By directly inhibiting Aurora kinase A, AJI-214 prevents mitotic progression and cell polarity in T cells while concurrently suppressing JAK2 activation to reduce STAT3 phosphorylation. This inhibition decreases the differentiation of TH1 and TH17 cells. AJI-214 is utilized in research focused on the modulation of immune responses and the prevention of graft-versus-host disease (GVHD).Formule :C17H13ClFN5OCouleur et forme :SolidMasse moléculaire :357.77YAP/TAZ inhibitor-4
YAP/TAZ Inhibitor-4 (Compound 45) acts as an inhibitor of YAP/TAZ, exhibiting inhibitory activity on TEAD transcriptional activation by preventing the interaction between YAP or TAZ and TEAD.Formule :C28H28F3N3O3Couleur et forme :SolidMasse moléculaire :511.54Casein kinase 1δ-IN-8
CAS :Casein kinase 1δ-IN-8 is an inhibitor of casein kinase 1δ and is used to treat neurodegenerative diseases such as Alzheimer's disease type.Formule :C19H14FN5OSDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :379.41NMS-P715
CAS :NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).Formule :C35H39F3N8O3Degré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :676.73Cucurbitacin A
CAS :Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/Formule :C32H46O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :574.7WDR5-IN-6
CAS :WDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus.WDR5-IN-6 is highly synergistic with OICR-9429, a WDR5 inhibitor that targets the WIN locus.WDR5-IN-6Formule :C13H8Cl2N2O2SDegré de pureté :99.69%Couleur et forme :SoildMasse moléculaire :327.19JAK kinase-IN-1
CAS :JAK kinase-IN-1 (Example 1) functions as a potent inhibitor targeting the JAK family, which includes TYK2, JAK1, JAK2, and JAK3, with IC50 values of 4.2 nM, 32Formule :C17H19F2N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :407.44ITK inhibitor 2
CAS :ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor , with an IC50 of 2 nM.Formule :C25H33N5O2Couleur et forme :SolidMasse moléculaire :435.56CCG-232964
CAS :CCG-232964 is an orally active Rho/MRTF/SRF inhibitor that suppresses LPA-induced CTGF gene expression [1].Formule :C15H15ClN2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.81LX7101
CAS :LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).Formule :C23H29N7O3Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :451.52Dehydroglyasperin D
CAS :Dehydroglyasperin D exhibits anticancer, anti-inflammatory, anti-obesity, antioxidant and anti-aldose reductase effects, it inhibits the proliferation of HT-29Formule :C22H24O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.42Ripasudil free base
CAS :Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent.Formule :C15H18FN3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.39Ref: TM-T7492
1mg80,00€5mg159,00€10mg250,00€25mg558,00€50mg922,00€100mg1.540,00€1mL*10mM (DMSO)170,00€PMMB-187
CAS :PMMB-187, a selective STAT3 inhibitor, exhibits an IC50 of 1.81 μM in MDA-MB-231 cells. This compound induces apoptosis in MDA-MB-231 cells by inhibiting STAT3 transcriptional activity and nuclear translocation, reducing mitochondrial membrane potential, increasing reactive oxygen species (ROS) production, and upregulating the expression of apoptosis-related proteins. PMMB-187 is useful for research in the field of cancer.Formule :C27H23BrN2O6S2Couleur et forme :SolidMasse moléculaire :615.52SR-3677
CAS :SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).Formule :C22H24N4O4Degré de pureté :98.46%Couleur et forme :SolidMasse moléculaire :408.45ZINC00881524
CAS :ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.Formule :C21H20N2O3SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :380.46Wnt pathway activator 2
CAS :Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.Formule :C17H15NO4Degré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :297.31Ref: TM-T13345
1mg49,00€5mg105,00€10mg169,00€25mg344,00€50mg562,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)116,00€Rat GDF10(GrowthDifferentiation Factor 10) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat GDF10. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat GDF10. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat GDF10, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat GDF10 in the samples is then determined by comparing the OD of the samples to the standard curve.Couleur et forme :Colourless TransparentliquidStafia-1
CAS :Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.Formule :C24H27O10PDegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :506.44Ref: TM-T9339
1mg86,00€5mg187,00€10mg309,00€25mg525,00€50mg757,00€100mg1.035,00€500mg2.110,00€1mL*10mM (DMSO)217,00€ITD-1
CAS :ITD-1 is a potent and highly selective TGFβ pathway inhibitor.Formule :C27H29NO3Degré de pureté :100% - 99.89%Couleur et forme :SolidMasse moléculaire :415.52JAK-IN-31
CAS :JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 µM for JAK1, ≤0.01 µM for JAK2, 0.01-0.1 µM for JAK3, and ≤0.01 µM for Tyk2,Formule :C21H19N7O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :465.55Human ASPP1(Apoptosis-stimulating of p53 protein 1) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ASPP1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ASPP1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human ASPP1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human ASPP1 in the samples is then determined by comparing the OD of the samples to the standard curve.Couleur et forme :Colourless TransparentliquidJW74
CAS :JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).Formule :C24H20N6O2SDegré de pureté :95.00%Couleur et forme :SolidMasse moléculaire :456.52DT-6
CAS :DT-6, a potent TGF-β1 inhibitor, impedes M2 macrophage-induced epithelial-to-mesenchymal transition and the invasive migration of cancer cells, thereby showingFormule :C89H130N20O29S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2008.23CCT251545
CAS :CCT251545 is an potent and oral-bioavailable WNT signaling inhibitor(IC50 of 5 nM in 7dF3 cells).Formule :C23H24ClN5ODegré de pureté :98.2% - 98.69%Couleur et forme :SolidMasse moléculaire :421.92APTSTAT3-9R acetate
APTSTAT3-9R acetate is a selective peptide binding STAT3 with antiproliferative and antitumor activity.Formule :C225H334N80O53Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5007.56Belumosudil
CAS :Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).Formule :C26H24N6O2Degré de pureté :97.64% - 98.59%Couleur et forme :SolidMasse moléculaire :452.51Ref: TM-T6867
2mg48,00€5mg73,00€10mg90,00€25mg166,00€50mg250,00€100mg376,00€500mg895,00€1mL*10mM (DMSO)79,00€TP0427736
CAS :TP0427736: ALK5 inhibitor, IC50=2.72 nM, 300x > ALK3 selectivity; counters TGF-β in human cells, extends anagen in mice.Formule :C14H10N4S2Degré de pureté :97.67%Couleur et forme :SolidMasse moléculaire :298.39Antitumor agent-73
CAS :Antitumor Agent-73, derived from Diosgenin, blocks STAT3 and activates Pdia3, showing strong cancer cell line efficacy.Formule :C50H82BrO4PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :858.06BML-284
CAS :BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.Formule :C19H18N4O3Degré de pureté :99.66% - 99.91%Couleur et forme :SolidMasse moléculaire :350.37Ref: TM-T3144
5mg60,00€10mg88,00€25mg140,00€50mg253,00€100mg427,00€200mg615,00€500mg938,00€1mL*10mM (DMSO)66,00€hAChE-IN-5
hAChE-IN-5 (compound 49) is a dual inhibitor of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBuChE), exhibiting inhibitory potency withDegré de pureté :98%Couleur et forme :Odour SolidYAP-TEAD-IN-2
CAS :YAP-TEAD-IN-2 (compound 6) serves as a potent inhibitor of the YAP-TEAD protein-protein interaction (PPI), demonstrating an inhibitory concentration 50 (IC50)Formule :C25H24ClFN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :470.92JAK-IN-34
CAS :JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 0.40 nM for JAK1, 0.83 nM for JAK2, 2.10 nM for JAK3,Formule :C27H26N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :450.53VP3.15 dihydrobromide
CAS :VP3.15 dihydrobromide: potent, oral, CNS-penetrant PDE7/GSK3 inhibitor; IC50s: PDE7- 1.59 μM, GSK- 0.88 μM.Formule :C20H24Br2N4OSDegré de pureté :96.68% - ≥95%Couleur et forme :SolidMasse moléculaire :528.3Ref: TM-T5956
2mg47,00€5mg70,00€10mg96,00€25mg216,00€50mg376,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)81,00€Ac-ESMD-CHO
CAS :Ac-ESMD-CHO functions as an inhibitor of both caspase-3 and caspase-7, specifically obstructing the proteolytic cleavage of the caspase-3 precursor peptide (Formule :C19H30N4O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.53WAY-656935
CAS :WAY-656935 inhibits ROCK.Formule :C20H28ClN3O3SDegré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :425.97SD-208
CAS :SD-208 (ALK5 Inhibitor V), a selective TGF-βRI (ALK5) inhibitor (IC50: 48 nM), is >100-fold selectivity over TGF-βRII.Formule :C17H10ClFN6Degré de pureté :98.72% - 99.65%Couleur et forme :SolidMasse moléculaire :352.75Ref: TM-T2109
2mg38,00€5mg55,00€10mg74,00€25mg144,00€50mg213,00€100mg339,00€200mg502,00€1mL*10mM (DMSO)81,00€ROCK-IN-8
CAS :ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and gastro-intestinal disease research,Formule :C30H25FN4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :556.61Ceftriaxone Sodium
CAS :Ceftriaxone Sodium is a sporotaxin antibiotic that inhibits GSK3β and Aurora B. It is used in the study of sepsis and infective endocarditis.Formule :C18H17N8NaO7S3Couleur et forme :SolidMasse moléculaire :576.562Y-9738
CAS :Y-9738 is an agent of hypolipidemic.Formule :C15H16ClNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :309.74S3I-201
CAS :S3I-201 (S3I-201) is a selective Stat3 inhibitor (IC50: 86±33 μM) and low effect towards STAT1/5.Formule :C16H15NO7SDegré de pureté :97.83%Couleur et forme :SolidMasse moléculaire :365.36JAK3/BTK-IN-2
CAS :JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.Formule :C25H32N8O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :476.57Aβ42 agonist-1
CAS :Aβ42 agonist-1 is a small molecule compound with anti-cancer activity and NF-κB inhibitory properties, inducing Aβ42 aggregation.Formule :C15H11NO2Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :237.25IM-12
CAS :IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.Formule :C22H20FN3O2Degré de pureté :100% - 99.71%Couleur et forme :SolidMasse moléculaire :377.41Ref: TM-T2261
5mg52,00€10mg87,00€25mg155,00€50mg283,00€100mg469,00€500mg1.035,00€1mL*10mM (DMSO)58,00€DAPM
CAS :DAPM (gamma-Secretase Inhibitor XVI) is a Notch pathway inhibitor with anticancer activity and antiproliferative effects.Formule :C20H20F2N2O4Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :390.38Thiazovivin
CAS :Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.Formule :C15H13N5OSDegré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :311.36Ref: TM-T2155
1mg35,00€2mg52,00€5mg74,00€10mg115,00€25mg210,00€50mg380,00€100mg567,00€1mL*10mM (DMSO)82,00€Anti-NANOG Antibody (1M448)
Anti-NANOG Antibody (1M448) is a Mouse antibody targeting NANOG. Anti-NANOG Antibody (1M448) can be used in ELISA, WB, ICC, IF, FCM.Degré de pureté :>95%Couleur et forme :Odour LiquidMBM-55S
CAS :MBM-55S, a Nek2 inhibitor with 1 nM IC50, induces cell cycle arrest and apoptosis, suppressing tumor growth.Formule :C36H39FN6O10Degré de pureté :98.38% - 98.73%Couleur et forme :SolidMasse moléculaire :734.73Ref: TM-T11961
1mg185,00€2mg279,00€5mg426,00€10mg627,00€25mg938,00€50mg1.320,00€100mg1.786,00€500mg3.591,00€1mL*10mM (DMSO)630,00€AS1517499
CAS :AS1517499 is a potent STAT6 inhibitor with IC50 of 21 nMFormule :C20H20ClN5O2Degré de pureté :98.27% - 98.7%Couleur et forme :SolidMasse moléculaire :397.86Ref: TM-T4476
1mg40,00€2mg52,00€5mg88,00€10mg119,00€25mg235,00€50mg376,00€100mg469,00€500mg1.064,00€1mL*10mM (DMSO)87,00€Anti-GPC3 Antibody (4L576)
Anti-GPC3 Antibody (4L576) is an antibody targeting GPC3. Anti-GPC3 Antibody (4L576) can be used in ELISA, WB, IF.Couleur et forme :Odour LiquidWAY-262611
CAS :WAY262611 is a Wnt/β-catenin agonist and an inhibitor of Dkk1. It increases bone formation rate with EC50 of 0.63 μM in TCF-luciferase assay.Formule :C20H22N4Degré de pureté :98.09% - 99.09%Couleur et forme :SolidMasse moléculaire :318.42STAT3-IN-3
CAS :STAT3-IN-3 is a potent and selective signal transducer inhibitor and transcription 3 (STAT3) activator.Formule :C27H26BrN3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :600.48Glasdegib
CAS :Glasdegib (PF-04449913) (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2.Formule :C21H22N6ODegré de pureté :98.72%Couleur et forme :SolidMasse moléculaire :374.44CHIR 98024
CAS :CHIR 98024: strong GSK-3α/β blocker, IC50 0.65/0.58 nM, selective over Cdc2/ERK2.Formule :C20H17Cl2N9O2Degré de pureté :96.74%Couleur et forme :SolidMasse moléculaire :486.31Ref: TM-T3074
1mg44,00€2mg55,00€5mg96,00€10mg153,00€25mg298,00€50mg487,00€100mg705,00€1mL*10mM (DMSO)97,00€Adavivint
CAS :Adavivint (Adavivint (SM04690)) (SM04690) is a Wnt pathway inhibitor.Formule :C29H24FN7ODegré de pureté :98.27% - 98.6%Couleur et forme :SolidMasse moléculaire :505.55CCT 031374 hydrobromide
CAS :CCT 031374 hydrobromide is a TCF/β-catenin inhibitor with antitumor activities.Formule :C23H20BrN3ODegré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :434.33Ref: TM-T21685
1mg38,00€5mg71,00€10mg105,00€25mg207,00€50mg329,00€100mg472,00€200mg620,00€1mL*10mM (DMSO)87,00€CBT-295
CBT-295, an orally active autotaxin (ATX) inhibitor, effectively decreases inflammatory cytokines including TGF-β, TNF-α, and IL-6, along with the bile duct proliferation marker CK-19, and ameliorates liver fibrosis. The compound's ability to reverse liver fibrosis contributes to lowered ammonia levels in the blood and brain, which in turn reduces ammonia-induced neuroinflammation. CBT-295 shows potential for the study of liver cirrhosis and related encephalopathy.Formule :C18H20ClN3OCouleur et forme :SolidMasse moléculaire :329.82MYF-01-37
CAS :MYF-01-37 (1-[3-Methyl-3-[3-(trifluoromethyl)anilino]pyrrolidin-1-yl]prop-2-en-1-one) is a novel covalent TEAD inhibitor.Formule :C15H17F3N2ODegré de pureté :98.72% - 99.46%Couleur et forme :SolidMasse moléculaire :298.3Ref: TM-T22372
2mg40,00€5mg60,00€10mg96,00€25mg170,00€50mg298,00€100mg444,00€500mg938,00€1mL*10mM (DMSO)66,00€SMO-IN-2
CAS :SMO-IN-2 is a SMO inhibitor with antiproliferative activity and anticancer activity and inhibits Hh signaling.SMO-IN-2 can be used in the study of cancer.Formule :C25H25F4N5O2Degré de pureté :98.64%Couleur et forme :SolidMasse moléculaire :503.49Crenigacestat
CAS :Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested.Formule :C22H23F3N4O4Degré de pureté :97.27% - 98.76%Couleur et forme :SolidMasse moléculaire :464.44VT103
CAS :VT103, an oral TEAD1 palmitoylation inhibitor, shows promise against various cancers by disrupting YAP/TAZ-TEAD interactions.Formule :C18H17F3N4O2SDegré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :410.41Ref: TM-T62077
1mg124,00€5mg298,00€10mg472,00€25mg817,00€50mg1.198,00€100mg1.730,00€200mg2.337,00€1mL*10mM (DMSO)328,00€CHZ868
CAS :CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.Formule :C22H19F2N5O2Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :423.42Silmitasertib
CAS :Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).Formule :C19H12ClN3O2Degré de pureté :98% - 99.90%Couleur et forme :SolidMasse moléculaire :349.77Ref: TM-T2259
1mg40,00€2mg51,00€5mg85,00€10mg125,00€25mg207,00€50mg329,00€100mg520,00€500mg1.111,00€1mL*10mM (DMSO)93,00€KenPaullone
CAS :KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation.Formule :C16H11BrN2ODegré de pureté :97.14% - 98.99%Couleur et forme :Tan SolidMasse moléculaire :327.18Ref: TM-T2247
1mg38,00€2mg49,00€5mg70,00€10mg95,00€25mg188,00€50mg319,00€100mg474,00€500mg1.074,00€1mL*10mM (DMSO)74,00€SWTX-143
CAS :SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptionalFormule :C19H18F3N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :361.3620(S)-Hydroxycholesterol
CAS :20(S)-Hydroxycholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo).Formule :C27H46O2Degré de pureté :99.25% - 99.25%Couleur et forme :SolidMasse moléculaire :402.65γ-secretase modulator 1
CAS :gamma-secretase modulator 1 is a modulator of γ secretase and can be used in studies about the treatment of Alzheimer's disease.Formule :C24H24N4OSDegré de pureté :99.48% - 99.75%Couleur et forme :SolidMasse moléculaire :416.54IWP-4
CAS :IWP-4 (Inhibitor of Wnt Production-4) is a potent Wnt inhibitor.Formule :C23H20N4O3S3Degré de pureté :100.00%Couleur et forme :SolidMasse moléculaire :496.62ML116
CAS :ML116 is a potent and selective STAT3 inhibitor.Formule :C18H19N3SDegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :309.43Ref: TM-T8597
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)170,00€Cardiogenol C hydrochloride
CAS :Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).Formule :C13H17ClN4O2Degré de pureté :99.89% - 99.94%Couleur et forme :SolidMasse moléculaire :296.75TNIK-IN-7
CAS :TNIK-IN-7 is a Traf2 and Nck interacting kinase (TNIK) inhibitor with antitumor activity for the study of signaling and proliferation in colorectal cancer cellsFormule :C23H22N4O2Degré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :386.45Tankyrase-IN-2
CAS :Tankyrase-IN-2 is a selective, potent and orally active inhibitor of tankyrase with IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectivelyFormule :C17H14F2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :316.3Afuresertib
CAS :Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplasticFormule :C18H17Cl2FN4OSDegré de pureté :97.51% - 99.17%Couleur et forme :SolidMasse moléculaire :427.32Ref: TM-T1911
1mg39,00€2mg50,00€5mg79,00€10mg97,00€25mg170,00€50mg274,00€100mg477,00€500mg1.035,00€1mL*10mM (DMSO)79,00€Rat Cys-C(Cystatin C) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat Cys-C. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat Cys-C. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat Cys-C, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat Cys-C in the samples is then determined by comparing the OD of the samples to the standard curve.Couleur et forme :Colourless TransparentliquidJAK1-IN-10
CAS :JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, functions as a potent and selective inhibitor of JAK1 [1].Formule :C15H17N7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.34BML-286
CAS :BML-286 is a WNT pathway modulator with potential anticancer activity and induces β-catenin- and TCF- dependent transcriptional activity.Formule :C22H18N2O4Couleur et forme :SolidMasse moléculaire :374.39JANEX-1
CAS :JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.Formule :C16H15N3O3Degré de pureté :98% - 99.73%Couleur et forme :SolidMasse moléculaire :297.31Ref: TM-T2045
1mg44,00€2mg55,00€5mg92,00€10mg150,00€25mg248,00€50mg444,00€100mg652,00€500mg1.378,00€1mL*10mM (DMSO)92,00€Elezanumab
CAS :Elezanumab (ABT-555) is a human anti-RGMa antibody blocking BMP signaling via SMAD1/5/8; IC50 ~97 pM. It aids neuroregeneration and repairs neuronal damage.Degré de pureté :SDS-PAGE:97.4%;SEC-HPLC:98.7%Couleur et forme :LiquidMasse moléculaire :143.43 kDa
