PDGFR
Les inhibiteurs du récepteur du facteur de croissance dérivé des plaquettes (PDGFR) sont des composés qui bloquent la signalisation du PDGFR, un récepteur impliqué dans la croissance cellulaire, la prolifération et l'angiogenèse. Le PDGFR joue un rôle significatif dans le développement des vaisseaux sanguins qui alimentent les tumeurs. Inhiber le PDGFR peut donc empêcher l'angiogenèse, ce qui rend ces inhibiteurs précieux en thérapie anticancéreuse. Chez CymitQuimica, nous offrons une sélection d'inhibiteurs de PDGFR de haute qualité pour soutenir vos recherches en oncologie, biologie vasculaire et angiogenèse.
Produits appartenant à la catégorie "PDGFR"
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Anti-PDGFRB Antibody-FITC (7C914)
Anti-PDGFRB Antibody-FITC (7C914) is a FITC-conjugated Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody-FITC (7C914) can be used in FCM.Couleur et forme :Odour LiquidSU4984
CAS :SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).Formule :C20H19N3O2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :333.38PD168393
CAS :PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Formule :C17H13BrN4ODegré de pureté :99.13% - 99.7%Couleur et forme :SolidMasse moléculaire :369.22Ref: TM-T6932
1mg39,00€2mg49,00€5mg66,00€10mg89,00€25mg155,00€50mg222,00€100mg310,00€1mL*10mM (DMSO)56,00€Multi-kinase inhibitor 1
CAS :Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Formule :C20H17F3N4O3Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :418.37Tyrphostin A9
CAS :Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFormule :C18H22N2ODegré de pureté :98.21% - 99.87%Couleur et forme :Yellow SolidMasse moléculaire :282.38SU16f
CAS :SU16f, a 3-substituted indolin-2-one, is a selective PDGFRβ inhibitor; IC50: 10 nM (PDGFRβ), 140 nM (PDGFR1), 2.29 μM (PDGFR2), halts GC cell growth.Formule :C24H22N2O3Degré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :386.44TAK-593
CAS :TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).Formule :C23H23N7O3Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :445.47Ref: TM-T16975
2mg44,00€5mg65,00€10mg101,00€25mg192,00€50mg299,00€100mg432,00€200mg607,00€1mL*10mM (DMSO)77,00€PDGFRB Protein, Human, Recombinant (His)
PDGFRB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :57.6 kDa (predicted); 95-100 kDa (reducing conditions)PDGFRB Protein, Human, Recombinant (His), Biotinylated
PDGFRB Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :57.6 kDa (predicted)Dovitinib lactate hydrate
CAS :Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formule :C24H27FN6O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :482.51Tyrphostin A9
CAS :Formule :C18H22N2ODegré de pureté :>98.0%(GC)Couleur et forme :Light orange to Yellow to Green powder to crystalMasse moléculaire :282.39Nintedanib
CAS :Formule :C31H33N5O4Degré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Yellow to Yellow green powder to crystalMasse moléculaire :539.64Imatinib
CAS :Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormule :C29H31N7ODegré de pureté :100% - 99.94%Couleur et forme :Off White PowderMasse moléculaire :493.6Anti-PDGFRB Antibody-FITC (1A610)
Anti-PDGFRB Antibody-FITC (1A610) is a FITC-conjugated Mouse antibody targeting PDGFRB. Anti-PDGFRB Antibody-FITC (1A610) can be used in FCM.Couleur et forme :Odour LiquidAnti-PDGFRB Antibody (7C914)
Anti-PDGFRB Antibody (7C914) is a Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody (7C914) can be used in FCM.Couleur et forme :Odour LiquidSeralutinib
CAS :Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.Formule :C27H27N5O3Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :469.54Ref: TM-T8900
1mg49,00€2mg65,00€5mg97,00€10mg144,00€25mg250,00€50mg329,00€100mg525,00€1mL*10mM (DMSO)97,00€AC710
CAS :AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ).Formule :C31H42N6O4Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :562.7N-Desmethyl imatinib
CAS :N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Formule :C28H29N7ODegré de pureté :98.60%Couleur et forme :Off-White To Pale-Yellow SolidMasse moléculaire :479.58Ref: TM-T11641
1mg92,00€5mg170,00€10mg319,00€25mg540,00€50mg777,00€100mg1.074,00€1mL*10mM (DMSO)178,00€PDGFR Tyrosine Kinase Inhibitor III
CAS :PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor thatFormule :C27H27N5O4Degré de pureté :99.64%Couleur et forme :SoildMasse moléculaire :485.53Ref: TM-T60108
5mg52,00€10mg78,00€25mg160,00€50mg225,00€100mg325,00€200mg445,00€1mL*10mM (DMSO)50,00€Sorafenib Tosylate
CAS :Formule :C21H16ClF3N4O3·C7H8O3SDegré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :637.03Lenvatinib mesylate
CAS :Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Formule :C22H23ClN4O7SDegré de pureté :99.03% - 99.79%Couleur et forme :SolidMasse moléculaire :522.96Imatinib Mesylate
CAS :Formule :C29H31N7O·CH4O3SDegré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :589.72Imatinib
CAS :Formule :C29H31N7ODegré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :493.62Tyrphostin RG 13022
CAS :Formule :C16H14N2O2Degré de pureté :>98.0%(GC)Couleur et forme :White to Yellow to Green powder to crystalMasse moléculaire :266.30Anti-PDGFRB Antibody-APC (1A610)
Anti-PDGFRB Antibody-APC (1A610) is a APC-conjugated Mouse antibody targeting PDGFRB. Anti-PDGFRB Antibody-APC (1A610) can be used in FCM.Couleur et forme :Odour LiquidCP-673451
CAS :CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than otherFormule :C24H27N5O2Degré de pureté :99.62% - 99.88%Couleur et forme :SolidMasse moléculaire :417.5Ref: TM-T6091
1mg52,00€2mg66,00€5mg96,00€10mg180,00€25mg354,00€50mg540,00€100mg778,00€500mg1.605,00€1mL*10mM (DMSO)114,00€Nintedanib esylate
CAS :Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFormule :C31H33N5O4·C2H6O3SDegré de pureté :99.43% - 99.96%Couleur et forme :SolidMasse moléculaire :649.76Ref: TM-T5001
5mg43,00€10mg57,00€25mg71,00€50mg85,00€100mg105,00€200mg164,00€500mg316,00€1mL*10mM (DMSO)63,00€AG 1295
CAS :AG 1295 is a selective PDGFR tyrosine-kinase inhibitor; it blocks PDGFR autophosphorylation without affecting EGF receptor.Formule :C16H14N2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :234.3JNJ-10198409
CAS :JNJ-10198409: selective ATP competitive PDGF-RTK inhibitor; IC50: PDGFR-β 4.2 nM, PDGFR-α 45 nM; antiangiogenic & antiproliferative.Formule :C18H16FN3O2Degré de pureté :98.51%Couleur et forme :SolidMasse moléculaire :325.34Ref: TM-T15616
1mg34,00€5mg96,00€10mg129,00€25mg210,00€50mg309,00€100mg442,00€200mg620,00€1mL*10mM (DMSO)104,00€Dovitinib lactate
CAS :Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formule :C24H27FN6O4Degré de pureté :98.44% - 99.54%Couleur et forme :SolidMasse moléculaire :482.51Ref: TM-T7104
5mg51,00€10mg79,00€25mg129,00€50mg213,00€100mg358,00€200mg535,00€500mg843,00€1mL*10mM (DMSO)57,00€TCS 359
CAS :Formule :C18H20N2O4SDegré de pureté :>98.0%(HPLC)Couleur et forme :Light yellow to Brown powder to crystalMasse moléculaire :360.43Avapritinib
CAS :Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.Formule :C26H27FN10Degré de pureté :96.59% - 99.7%Couleur et forme :SolidMasse moléculaire :498.56Ref: TM-T5109
1mg88,00€5mg187,00€10mg305,00€25mg520,00€50mg748,00€100mg1.026,00€500mg2.072,00€1mL*10mM (DMSO)205,00€Sennoside B
CAS :Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation.Formule :C42H38O20Degré de pureté :92.85% - 98.92%Couleur et forme :Light Yellow CrystalMasse moléculaire :862.74PDGFRB Protein, Human, Recombinant
PDGFRB Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 56.2 kDa and the accession number is P09619-1.Couleur et forme :Lyophilized PowderMasse moléculaire :56.2 kDa (predicted)SU14813
CAS :SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formule :C23H27FN4O4Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :442.48Tyrphostin AG1296
CAS :Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formule :C16H14N2O2Degré de pureté :99.66% - 99.68%Couleur et forme :SolidMasse moléculaire :266.29Ref: TM-T6711
2mg40,00€5mg58,00€10mg90,00€25mg180,00€50mg279,00€100mg411,00€200mg585,00€1mL*10mM (DMSO)81,00€Flumatinib
CAS :Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Formule :C29H29F3N8ODegré de pureté :99.52% - 99.95%Couleur et forme :SolidMasse moléculaire :562.59Ref: TM-T4320
1mg35,00€5mg66,00€10mg87,00€25mg127,00€50mg163,00€100mg273,00€200mg409,00€500mg677,00€1mL*10mM (DMSO)87,00€Linifanib
CAS :Formule :C21H18FN5ODegré de pureté :>95.0%(HPLC)(qNMR)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :375.41AG-1296
CAS :Formule :C16H14N2O2Degré de pureté :>98.0%(GC)Couleur et forme :White to Orange to Green powder to crystalMasse moléculaire :266.30Toceranib
CAS :Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.Formule :C22H25FN4O2Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :396.46Regorafenib
CAS :Formule :C21H15ClF4N4O3Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :482.82PDGFR-IN-1
CAS :PDGFR-IN-1 is a platelet-derived growth factor receptor (PDGFR) inhibitor, strongly inhibiting PDGFRα and PDGFRβ, useful for studying solid tumors.Formule :C25H30N8ODegré de pureté :99.13% - 99.49%Couleur et forme :SolidMasse moléculaire :458.56Ref: TM-T62872
1mg180,00€5mg455,00€10mg692,00€25mg1.216,00€50mg1.758,00€100mg2.375,00€1mL*10mM (DMSO)459,00€Tyrphostin AG1433
CAS :Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).Formule :C16H14N2O2Degré de pureté :97.51%Couleur et forme :SolidMasse moléculaire :266.29Ref: TM-T13238
1mg52,00€5mg97,00€10mg160,00€25mg271,00€50mg416,00€100mg620,00€500mg1.283,00€1mL*10mM (DMSO)111,00€Bisindolylmaleimide I
CAS :Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Formule :C25H24N4O2Degré de pureté :98.19% - 99.08%Couleur et forme :Orange SolidMasse moléculaire :412.48Anti-PDGFRB Antibody-APC (7C914)
Anti-PDGFRB Antibody-APC (7C914) is a APC-conjugated Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody-APC (7C914) can be used in FCM.Couleur et forme :Odour LiquidAxitinib
CAS :Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.Formule :C22H18N4OSDegré de pureté :98.9% - 99.81%Couleur et forme :Off-White SolidMasse moléculaire :386.47PDGFRα kinase inhibitor 1
CAS :PDGFRα kinase inhibitor 1 is a type II PDGFRα kinase inhibitor that inhibits both PDGFRα and PDGFRβ.Formule :C34H34N8O2Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :586.69Nintedanib
CAS :Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/Formule :C31H33N5O4Degré de pureté :98% - 99.92%Couleur et forme :SolidMasse moléculaire :539.62Anti-Phospho-PDGFRB (Tyr740) Antibody (9D509)
Anti-Phospho-PDGFRB (Tyr740) Antibody (9D509) is an antibody targeting Phospho-PDGFRB (Tyr740). Anti-Phospho-PDGFRB (Tyr740) Antibody (9D509) can be used in ELISA, WB.Couleur et forme :Odour LiquidJI-101
CAS :JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formule :C22H20BrN5O2Degré de pureté :99.35% - 99.41%Couleur et forme :SolidMasse moléculaire :466.33
