PDGFR
Les inhibiteurs du récepteur du facteur de croissance dérivé des plaquettes (PDGFR) sont des composés qui bloquent la signalisation du PDGFR, un récepteur impliqué dans la croissance cellulaire, la prolifération et l'angiogenèse. Le PDGFR joue un rôle significatif dans le développement des vaisseaux sanguins qui alimentent les tumeurs. Inhiber le PDGFR peut donc empêcher l'angiogenèse, ce qui rend ces inhibiteurs précieux en thérapie anticancéreuse. Chez CymitQuimica, nous offrons une sélection d'inhibiteurs de PDGFR de haute qualité pour soutenir vos recherches en oncologie, biologie vasculaire et angiogenèse.
Produits appartenant à la catégorie "PDGFR"
Trier par
Regorafenib
CAS :Formule :C21H15ClF4N4O3Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :482.82PDGFR-IN-1
CAS :PDGFR-IN-1 is a platelet-derived growth factor receptor (PDGFR) inhibitor, strongly inhibiting PDGFRα and PDGFRβ, useful for studying solid tumors.Formule :C25H30N8ODegré de pureté :99.13% - 99.49%Couleur et forme :SolidMasse moléculaire :458.56Ref: TM-T62872
1mg180,00€5mg455,00€10mg692,00€25mg1.216,00€50mg1.758,00€100mg2.375,00€1mL*10mM (DMSO)459,00€Tyrphostin AG1433
CAS :Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).Formule :C16H14N2O2Degré de pureté :97.51%Couleur et forme :SolidMasse moléculaire :266.29Ref: TM-T13238
1mg52,00€5mg97,00€10mg160,00€25mg271,00€50mg416,00€100mg620,00€500mg1.283,00€1mL*10mM (DMSO)111,00€Bisindolylmaleimide I
CAS :Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Formule :C25H24N4O2Degré de pureté :98.19% - 99.08%Couleur et forme :Orange SolidMasse moléculaire :412.48Anti-PDGFRB Antibody-APC (7C914)
Anti-PDGFRB Antibody-APC (7C914) is a APC-conjugated Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody-APC (7C914) can be used in FCM.Couleur et forme :Odour LiquidAxitinib
CAS :Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.Formule :C22H18N4OSDegré de pureté :98.9% - 99.81%Couleur et forme :Off-White SolidMasse moléculaire :386.47PDGFRα kinase inhibitor 1
CAS :PDGFRα kinase inhibitor 1 is a type II PDGFRα kinase inhibitor that inhibits both PDGFRα and PDGFRβ.Formule :C34H34N8O2Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :586.69Nintedanib
CAS :Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/Formule :C31H33N5O4Degré de pureté :98% - 99.92%Couleur et forme :SolidMasse moléculaire :539.62Anti-Phospho-PDGFRB (Tyr740) Antibody (9D509)
Anti-Phospho-PDGFRB (Tyr740) Antibody (9D509) is an antibody targeting Phospho-PDGFRB (Tyr740). Anti-Phospho-PDGFRB (Tyr740) Antibody (9D509) can be used in ELISA, WB.Couleur et forme :Odour LiquidJI-101
CAS :JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formule :C22H20BrN5O2Degré de pureté :99.35% - 99.41%Couleur et forme :SolidMasse moléculaire :466.33Imatinib Mesylate
CAS :Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,Formule :C29H31N7O·CH4SO3Degré de pureté :100% - 99.97%Couleur et forme :White Crystalline PowderMasse moléculaire :589.71Masitinib
CAS :Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formule :C28H30N6OSDegré de pureté :100% - 99.55%Couleur et forme :SolidMasse moléculaire :498.64Ponatinib
CAS :Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormule :C29H27F3N6ODegré de pureté :98% - 99.60%Couleur et forme :SolidMasse moléculaire :532.56GZD856
CAS :GZD856 is an orally bioavailable PDGFRα/β inhibitor (IC50s: 68.6 and 136.6 nM) with anti-lung cancer activities.Formule :C29H27F3N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.56Flumatinib mesylate
CAS :Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.Formule :C30H33F3N8O4SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :658.69Ref: TM-T7861
1mg37,00€5mg88,00€10mg133,00€25mg250,00€50mg393,00€100mg628,00€500mg1.301,00€1mL*10mM (DMSO)139,00€Lenvatinib
CAS :Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Formule :C21H19ClN4O4Degré de pureté :98.46% - 99.8000%Couleur et forme :SolidMasse moléculaire :426.85CT52923
CAS :CT52923: selective oral PDGFR blocker, ATP-inhibitor, used in research for various diseases including cancer.Formule :C23H25N5O4SDegré de pureté :99.88%Couleur et forme :SoildMasse moléculaire :467.54Methylnissolin
CAS :Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.Formule :C17H16O5Degré de pureté :99.68% - 99.98%Couleur et forme :SolidMasse moléculaire :300.31PDGF R β/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :59 kDa (predicted). Due to glycosylation, the protein migrates to 78-115 kDa based on Tris-Bis PAGE result.ON123300
CAS :ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).Formule :C24H27N7ODegré de pureté :99.22% - 99.53%Couleur et forme :SolidMasse moléculaire :429.52
