Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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Cordycepin
CAS :Cordycepin (3'-Deoxyadenosine) is a purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplasticFormule :C10H13N5O3Degré de pureté :100% - 99.78%Couleur et forme :Crystalline SolidMasse moléculaire :251.24KJ Pyr 9
CAS :KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).Formule :C22H15N3O4Degré de pureté :98.07% - ≥98%Couleur et forme :SolidMasse moléculaire :385.37Ref: TM-T15665
2mg39,00€5mg57,00€10mg81,00€25mg145,00€50mg279,00€100mg510,00€200mg683,00€500mg1.064,00€1mL*10mM (DMSO)63,00€Clotrimazole
CAS :Clotrimazole (FB 5097), an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol.Formule :C22H17ClN2Degré de pureté :99.24%Couleur et forme :Crystals SolidMasse moléculaire :344.84Amsacrine
CAS :Amsacrine (AMSA) (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells.Formule :C21H19N3O3SDegré de pureté :98.59%Couleur et forme :Yellow Crystalline Powder SolidMasse moléculaire :393.46Quizartinib
CAS :Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.Formule :C29H32N6O4SDegré de pureté :98% - 99.42%Couleur et forme :SolidMasse moléculaire :560.67Ref: TM-T2066
5mg58,00€10mg79,00€25mg97,00€50mg127,00€100mg202,00€200mg300,00€500mg507,00€1mL*10mM (DMSO)71,00€Peptide R TFA
Peptide R (TFA) is a synthetic and specific CXCR4 antagonist. It demonstrates excellent tumor stroma remodeling capabilities and is applicable in research on solid tumors, such as glioblastoma.Formule :C39H57N13O8S2·xC2HF3O2Masse moléculaire :900.08 (free base)Tozasertib
CAS :Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formule :C23H28N8OSDegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :464.59Autophagy agonist-1
Autophagyagonist-1 (compound 22) is an autophagy agonist. It exhibits significant anticancer activity against HepG2 cells and normal cells, with IC50 values of 8.8 μM and > 50 μM, respectively. The compound induces G1/S phase cell cycle arrest, suppresses the expression of CDK4 and CyclinD1, and upregulates P21. Additionally, Autophagyagonist-1 enhances autophagosome, LC3, and PINK1 accumulation, thereby promoting autophagy and mitophagy in HepG2 cells.Formule :C33H41N3O5Couleur et forme :SolidMasse moléculaire :559.7Bromocriptine mesylate
CAS :Bromocriptine mesylate (CB-154) is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM)Formule :C33H44BrN5O8SDegré de pureté :99.76% - 99.87%Couleur et forme :White SolidMasse moléculaire :750.7Clofarabine
CAS :Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotideFormule :C10H11ClFN5O3Degré de pureté :100% - 99.94%Couleur et forme :White SolidMasse moléculaire :303.68Ref: TM-T0297
5mg43,00€10mg59,00€25mg95,00€50mg133,00€100mg172,00€200mg215,00€500mg360,00€1mL*10mM (DMSO)55,00€3'-Hydroxypterostilbene
CAS :3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.Formule :C16H16O4Degré de pureté :98.25% - 99.19%Couleur et forme :SolidMasse moléculaire :272.3RSVA405
CAS :RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitorFormule :C17H20N4O2Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :312.37Ethyl 3,4-dihydroxybenzoate
CAS :Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.Formule :C9H10O4Degré de pureté :99.88%Couleur et forme :White Crystal Or PowderMasse moléculaire :182.173BDO
CAS :3BDO is a new mTOR activator. 3BDO inhibits autophagy.Formule :C18H17NO5Degré de pureté :96.00%Couleur et forme :SolidMasse moléculaire :327.33Ref: TM-T14033
2mg47,00€5mg69,00€10mg97,00€25mg208,00€50mg331,00€100mg520,00€200mg777,00€500mg1.188,00€1mL*10mM (DMSO)74,00€Sitagliptin
CAS :Sitagliptin (MK0431), an oral DPP-4 inhibitor, treats type 2 diabetes alone or with metformin/thiazolidinedione by increasing incretins and insulin.Formule :C16H15F6N5ODegré de pureté :99.33% - 99.4%Couleur et forme :Yellow GreaseMasse moléculaire :407.31Tenovin-6 Hydrochloride
CAS :Tenovin-6 HCl: Inhibits SIRT1 (21µM), SIRT2 (10µM), HDAC8; potent p53 activator.Formule :C25H35ClN4O2SDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :491.09Ref: TM-T8480
1mg39,00€2mg51,00€5mg70,00€10mg88,00€25mg140,00€50mg226,00€100mg376,00€1mL*10mM (DMSO)73,00€Esmolol hydrochloride
CAS :Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension.Formule :C16H25NO4·HClDegré de pureté :98.72% - 99.48%Couleur et forme :White SolidMasse moléculaire :331.15GSK2656157
CAS :GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay.Formule :C23H21FN6ODegré de pureté :100% - 99.89%Couleur et forme :SolidMasse moléculaire :416.45Ref: TM-T2654
2mg35,00€5mg50,00€10mg81,00€25mg142,00€50mg259,00€100mg467,00€200mg632,00€1mL*10mM (DMSO)56,00€Norepinephrine bitartrate monohydrate
CAS :Norepinephrine bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator.Formule :C8H11NO3·C4H6O6·H2ODegré de pureté :97.88% - ≥95%Couleur et forme :SolidMasse moléculaire :337.28JZL195
CAS :JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.Formule :C24H23N3O5Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :433.46Fasudil hydrochloride
CAS :Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.Formule :C14H18ClN3O2SDegré de pureté :100% - ≥95%Couleur et forme :White SolidMasse moléculaire :327.83Perifosine
CAS :Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.Formule :C25H52NO4PDegré de pureté :100% - 99.94%Couleur et forme :SolidMasse moléculaire :461.66Sitagliptin phosphate monohydrate
CAS :Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.Formule :C16H15F6N5O·H3PO4·H2ODegré de pureté :99.65% - 99.85%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :523.33Enzastaurin
CAS :Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.Formule :C32H29N5O2Degré de pureté :100% - 99.24%Couleur et forme :SolidMasse moléculaire :515.6Guggulsterone
CAS :Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Formule :C21H28O2Degré de pureté :99.40% - 99.8%Couleur et forme :Light Yellow PowderMasse moléculaire :312.45Ref: TM-T5574
1mg35,00€5mg55,00€10mg93,00€25mg178,00€50mg245,00€100mg360,00€200mg532,00€1mL*10mM (DMSO)60,00€Oxidopamine hydrochloride
CAS :Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.Formule :C8H12ClNO3Degré de pureté :96.17% - 99.85%Couleur et forme :Physical Description Beige Solid (Ntp 1992)Masse moléculaire :205.64CA77.1
CAS :CA77.1(CA) is a novel chaperon-mediated autophagy (CMA) activator for the treatment of Alzheimer's disease (AD).Formule :C16H12ClN3ODegré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :297.74Cilengitide
CAS :Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Formule :C27H40N8O7Degré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :588.66Ref: TM-T2494
1mg49,00€2mg70,00€5mg96,00€10mg160,00€25mg274,00€50mg439,00€100mg632,00€1mL*10mM (DMSO)137,00€Ginkgolide K
CAS :Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.Formule :C20H22O9Degré de pureté :99.44% - 99.72%Couleur et forme :SolidMasse moléculaire :406.38Pemetrexed disodium
CAS :Pemetrexed disodium treats lung cancer/mesothelioma; may cause moderate serum enzyme elevation, rarely acute liver injury.Formule :C20H19N5Na2O6Degré de pureté :99.29% - 99.49%Couleur et forme :Crystalline SolidMasse moléculaire :471.37Sunitinib
CAS :Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFRβ (IC50=80/2 nM).Formule :C22H27FN4O2Degré de pureté :98% - 99.67%Couleur et forme :Yellow SolidMasse moléculaire :398.47Entinostat
CAS :Entinostat (MS-275) is an HDAC class I with oral activity. Entinostat has antitumor activity. Cost-effective and quality-assured.Formule :C21H20N4O3Degré de pureté :98% - 99.52%Couleur et forme :SolidMasse moléculaire :376.41Bergapten
CAS :Bergapten (5-Methoxypsoralen), a psoralen, inhibits cell replication.Formule :C12H8O4Degré de pureté :99.48% - ≥95%Couleur et forme :Needles From Alcohol; Soln In Sulfuric Acid Is Yellow-Gold Physical Description Grayish-White Micr°Crystalline Powder Or Yellow Fluffy Solid (Ntp 1992)Masse moléculaire :216.19Dacinostat
CAS :LAQ824 (Dacinostat (NVP-LAQ824)) is a novel HDAC inhibitor with IC50 of 32 nM and is an activator of the p21 promoter.Formule :C22H25N3O3Degré de pureté :95.28% - 95.28%Couleur et forme :SolidMasse moléculaire :379.45Ref: TM-T2454
1mg49,00€2mg67,00€5mg110,00€10mg180,00€25mg323,00€50mg487,00€100mg705,00€500mg1.444,00€1mL*10mM (DMSO)110,00€Luminespib
CAS :Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.Formule :C26H31N3O5Degré de pureté :98% - 99.26%Couleur et forme :SolidMasse moléculaire :465.54Ref: TM-T1989
5mg57,00€10mg81,00€25mg145,00€50mg221,00€100mg363,00€200mg540,00€500mg872,00€1mL*10mM (DMSO)63,00€Leonurine hydrochloride
CAS :Leonurine hydrochloride (SCM-198 hydrochloride) , a major alkaloid compound extracted from Leonurus japonicas Houtt.Formule :C14H22ClN3O5Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :347.79Isobavachalcone
CAS :Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury inFormule :C20H20O4Degré de pureté :98% - 99.76%Couleur et forme :SolidMasse moléculaire :324.37AMDE-1
CAS :AMDE-1, an autophagy modulator, triggers Atg5-dependent autophagy, recruits Atg16, and induces LC3 lipidation.Formule :C18H8ClF6N3Degré de pureté :90%Couleur et forme :SolidMasse moléculaire :415.72Forskolin
CAS :Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).Formule :C22H34O7Degré de pureté :98.83% - 99.86%Couleur et forme :Less Crystalline Solid Colorless Crystalline SolidMasse moléculaire :410.5Ref: TM-T2939
5mg43,00€10mg56,00€25mg86,00€50mg96,00€100mg144,00€200mg182,00€500mg306,00€1mL*10mM (DMSO)56,00€VPS34 inhibitor 1 (Compound 19, PIK-III analogue)
CAS :VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)Formule :C21H25N7ODegré de pureté :98.60%Couleur et forme :SolidMasse moléculaire :391.47Ref: TM-T7944
1mg66,00€5mg144,00€10mg227,00€25mg399,00€50mg567,00€100mg753,00€200mg1.035,00€1mL*10mM (DMSO)166,00€trifarotene
CAS :Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, with EC50 of 7.7 nM.Formule :C29H33NO4Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :459.58CCT128930 hydrochloride
CAS :CCT128930 hydrochloride: Potent AKT inhibitor (IC50=6 nM), 28x selective over PKA, 20x over p70S6K, induces cell cycle arrest & DNA damage.Formule :C18H21Cl2N5Degré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :378.3Dexamethasone
CAS :Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Formule :C22H29FO5Degré de pureté :98% - 99.91%Couleur et forme :Crystals From Ether (Ntp 1992)Masse moléculaire :392.46Deoxypodophyllotoxin
CAS :Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.Formule :C22H22O7Degré de pureté :99.21% - 99.84%Couleur et forme :SolidMasse moléculaire :398.41Mefloquine hydrochloride
CAS :Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Formule :C17H17ClF6N2ODegré de pureté :99% - 99.74%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :414.77SLF
CAS :SLF is a synthetic ligand for FKBP12 and increases Ca2+ efflux and protein synthesis.Formule :C30H40N2O6Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :524.65Trifluoperazine dihydrochloride
CAS :Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.Formule :C21H26Cl2F3N3SDegré de pureté :99.57% - 99.96%Couleur et forme :Cream Fine PowderMasse moléculaire :480.43Calcineurin substrate acetate
Calcineurin substrate acetate is from the regulatory RII subunit of cAMP-dependent protein kinase.Formule :C94H154N28O31Degré de pureté :97.59%Couleur et forme :SolidMasse moléculaire :2172.4Metformin
CAS :Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.Formule :C4H11N5Degré de pureté :100% - 99.78Couleur et forme :SolidMasse moléculaire :129.16Bosutinib
CAS :Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Formule :C26H29Cl2N5O3Degré de pureté :98.98% - 99.9%Couleur et forme :Yellowish-Orange Or Pink To Brownish Solid Solid PowderMasse moléculaire :530.45Cysteamine hydrochloride
CAS :Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an antioxidant.Formule :C2H7NS·HClDegré de pureté :99.34% - 99.87%Couleur et forme :White Crystalline Powder With A Strong And Disagreeable SmellMasse moléculaire :113.61AICAR
CAS :AICAR (Acadesine) 是一种AMPK 激活剂,引起ZMP积累,模拟AMP对AMPK和AMPKK的刺激作用,常用于糖尿病,心脑血管疾病以及肿瘤相关研究。Formule :C9H14N4O5Degré de pureté :98.00% - ≥95%Couleur et forme :SolidMasse moléculaire :258.23Selenomethionine
CAS :DL-Selenomethionine (SeMet) is a selenium analog of methionine, substituting sulfur with selenium, and can replace methionine in proteins.Formule :C5H11NO2SeDegré de pureté :98% - 99.95%Couleur et forme :Transparent Hexagonal Sheets Or Plates; Metallic Luster Of Crystals SolidMasse moléculaire :196.11UNC0638
CAS :UNC0638 inhibits G9a and GLP lysine methyltransferases with IC50 <15 nM and 19 nM, respectively, showing high selectivity.Formule :C30H47N5O2Degré de pureté :98.88% - 99.53%Couleur et forme :SolidMasse moléculaire :509.73Mefloquine
CAS :Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.Formule :C17H16F6N2ODegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :378.31Ref: TM-T0860L
1mg70,00€5mg154,00€10mg225,00€25mg376,00€50mg538,00€100mg755,00€200mg1.017,00€1mL*10mM (DMSO)160,00€Atorvastatin hemicalcium salt
CAS :Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.Formule :C33H34FN2O5CaDegré de pureté :99.27% - 99.89%Couleur et forme :White Crystalline PowderMasse moléculaire :577.67Tacrolimus monohydrate
CAS :Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FKBP to form a complex.Formule :C44H71NO13Degré de pureté :97.04% - 98.05%Couleur et forme :SolidMasse moléculaire :822.05Berberine chloride
CAS :Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.Formule :C20H18ClNO4Degré de pureté :98% - 99.93%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :371.8(1E,6E)-Bis(demethoxy)curcumin
CAS :(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.Formule :C19H16O4Degré de pureté :97.45%Couleur et forme :SolidMasse moléculaire :308.33ABT-737
CAS :ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.Formule :C42H45ClN6O5S2Degré de pureté :100% - 99.73%Couleur et forme :SolidMasse moléculaire :813.43D-CopA3
CAS :D-CopA3 is an inhibitor of MDM2 and an activator of the p53 signaling pathway. It exhibits cytotoxicity in colorectal cancer cells HCT-116, LoVo, and RKO with IC50 values of 15-18 μM and induces JNK/Beclin-1 mediated autophagy. D-CopA3 downregulates the expression of the cell cycle inhibitor protein p21Cip1/Waf1, enhances mucosal barrier function, and reduces infiltration of inflammatory mediators. It shows anti-inflammatory properties in mouse models of acute enteritis induced by C. difficile toxin A and chronic colitis induced by DSS. Additionally, D-CopA3 demonstrates antitumor activity in a mouse HCT-116 xenograft model.Formule :C96H184N30O18S2Couleur et forme :SolidMasse moléculaire :2110.816-Mercaptopurine
CAS :6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties.Formule :C5H4N4SDegré de pureté :99.53% - 99.63%Couleur et forme :Yellow Crystalline Powder SolidMasse moléculaire :152.18Nocodazole
CAS :Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Formule :C14H11N3O3SDegré de pureté :98% - 99.91%Couleur et forme :Physical Description White Powder (Ntp 1992)Masse moléculaire :301.32Ref: TM-T2802
5mg37,00€10mg55,00€25mg99,00€50mg168,00€100mg283,00€200mg420,00€500mg682,00€1mL*10mM (DMSO)40,00€Penfluridol
CAS :Penfluridol (TLP-607) is a highly potent antipsychotic.Formule :C28H27ClF5NODegré de pureté :98.9% - 99.73%Couleur et forme :Off-White To White Crystalline PowderMasse moléculaire :523.97Scriptaid
CAS :Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3.Formule :C18H18N2O4Degré de pureté :96.74% - 99.45%Couleur et forme :SolidMasse moléculaire :326.35Ref: TM-T6980
5mg71,00€10mg97,00€25mg205,00€50mg378,00€100mg567,00€500mg1.198,00€1mL*10mM (DMSO)79,00€Lamotrigine
CAS :Lamotrigine (BW430C) is an Anti-epileptic Agent and Mood Stabilizer.Formule :C9H7Cl2N5Degré de pureté :99.76% - 99.95%Couleur et forme :White To Pale Cream-Colored Powder Crystals From Isopropanol SolidMasse moléculaire :256.09Sitagliptin phosphate
CAS :Sitagliptin phosphate (MK-0431 phosphate) is a dipeptidyl peptidase-4 (DPP4) inhibitor.Formule :C16H18F6N5O5PDegré de pureté :99.72% - 99.72%Couleur et forme :White SolidMasse moléculaire :505.31Sophocarpine
CAS :Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.Formule :C15H22N2ODegré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :246.35Nitroprusside disodium dihydrate
CAS :Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.Formule :C5H4FeN6Na2O3Degré de pureté :98%Couleur et forme :Bright RedMasse moléculaire :297.95Dimethyl fumarate
CAS :Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.Formule :C6H8O4Degré de pureté :100% - 99.88%Couleur et forme :White To Off-White Powder White Crystalline PowderMasse moléculaire :144.13Letrozole
CAS :Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.Formule :C17H11N5Degré de pureté :98.67% - 99.84%Couleur et forme :White To Off-Whitecrystalline PowderMasse moléculaire :285.3MRT68921 dihydrochloride
CAS :MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).Formule :C25H36Cl2N6ODegré de pureté :100% - 98.91%Couleur et forme :SolidMasse moléculaire :507.499Eprenetapopt
CAS :Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Formule :C10H17NO3Degré de pureté :98.75% - 99.57%Couleur et forme :SolidMasse moléculaire :199.25Ref: TM-T4414
5mg73,00€10mg105,00€25mg207,00€50mg368,00€100mg652,00€500mg1.320,00€1mL*10mM (DMSO)81,00€3-Bromopyruvic acid
CAS :3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.Formule :C3H3BrO3Degré de pureté :95% - 95%Couleur et forme :White To Pale Yellow Crystalline PowderMasse moléculaire :166.96SB 239063
CAS :SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.Formule :C20H21FN4O2Degré de pureté :99.42% - 99.81%Couleur et forme :SolidMasse moléculaire :368.4Corosolic acid
CAS :Corosolic acid inhibits angiogenesis, suppresses FAK, fights various cancers, induces apoptosis, and degrades β-catenin.Formule :C30H48O4Degré de pureté :99.46% - 99.88%Couleur et forme :Fine-Brown Yellow PowderMasse moléculaire :472.7OSU-T315
CAS :OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Formule :C30H30F3N5ODegré de pureté :98.03%Couleur et forme :SolidMasse moléculaire :533.59Ref: TM-T5485
1mg97,00€2mg144,00€5mg235,00€10mg378,00€25mg647,00€50mg920,00€100mg1.225,00€500mg2.498,00€1mL*10mM (DMSO)306,00€Gavilimomab
CAS :Gavilimomab(ABX-CBL) is a murine-derived IgM monoclonal antibody against CD147 antigen used in immunosuppressive treatments for glucocorticoid-resistant GVHD).Degré de pureté :95%Couleur et forme :LiquidSTF-62247
CAS :STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.Formule :C15H13N3SDegré de pureté :99.3% - 99.67%Couleur et forme :SolidMasse moléculaire :267.35Ref: TM-T6683
5mg37,00€10mg50,00€25mg97,00€50mg167,00€100mg283,00€200mg434,00€500mg702,00€1mL*10mM (DMSO)40,00€PX-478
CAS :PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.Formule :C13H20Cl4N2O3Degré de pureté :97% - ≥98%Couleur et forme :SolidMasse moléculaire :394.12p38-α MAPK-IN-1
CAS :p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM in EFC displacement assay and HTRF assay,respectively.Formule :C27H35N5O3Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :477.6Ref: TM-T12347
1mg88,00€5mg180,00€10mg281,00€25mg520,00€50mg777,00€100mg1.169,00€200mg1.568,00€1mL*10mM (DMSO)188,00€Cisatracurium besylate
CAS :Cisatracurium besylate (51W89) is a nondepolarizing skeletal muscle relaxant for intravenous administration.Formule :C53H72N2O12·2C6H5O3SDegré de pureté :99.57% - ≥95%Couleur et forme :White Or White Powder CategoryMasse moléculaire :1243.48Ref: TM-T1459
10mg47,00€25mg70,00€50mg111,00€100mg180,00€200mg264,00€500mg452,00€1mL*10mM (DMSO)60,00€4EGI-1
CAS :4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).Formule :C18H12Cl2N4O4SDegré de pureté :96.8% - 99.12%Couleur et forme :SolidMasse moléculaire :451.28Ivermectin
CAS :Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.Formule :C48H74O14Degré de pureté :94.11% - 97.74%Couleur et forme :SolidMasse moléculaire :875.09IKK 16
CAS :IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.Formule :C28H29N5OSDegré de pureté :98.76% - 99.61%Couleur et forme :SolidMasse moléculaire :483.63Ref: TM-T6176
1mg40,00€2mg52,00€5mg88,00€10mg139,00€25mg245,00€50mg406,00€100mg607,00€200mg845,00€1mL*10mM (DMSO)87,00€AICAR phosphate
CAS :AICAR phosphate (Acadesine phosphate) is an AMPK activator, an inhibitor of autophagy, YAP and mitophagy, and inhibits iNOS production.Formule :C9H14N4O5·xH3O4PDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :356.23Milciclib
CAS :Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. In Phase 2 trials.Formule :C25H32N8ODegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :460.57Ref: TM-T6081
1mg51,00€5mg106,00€10mg177,00€25mg376,00€50mg603,00€100mg905,00€200mg1.216,00€1mL*10mM (DMSO)110,00€Prazosin hydrochloride
CAS :Prazosin HCl, a synthetic antiadrenergic, treats hypertension, heart failure, and more by relaxing blood vessels with an unclear mechanism.Formule :C19H22ClN5O4Degré de pureté :99.87% - 99.89%Couleur et forme :White To Tan Powder Off-White To Yellow PowderMasse moléculaire :419.86Berbamine
CAS :Berbamine is a natural product extracted from Phellodendron amurense.Formule :C37H40N2O6Degré de pureté :98.92% - 99.64%Couleur et forme :White Crystal PowderMasse moléculaire :608.72Ganoderic acid A
CAS :Ganoderic acid A fights tumors, suppresses gene regulators, induces cancer cell death, and enhances cisplatin efficacy.Formule :C30H44O7Degré de pureté :99.31% - ≥95%Couleur et forme :SolidMasse moléculaire :516.67Ref: TM-T6S1141
1mg47,00€5mg97,00€10mg160,00€25mg250,00€50mg374,00€100mg547,00€1mL*10mM (DMSO)110,00€Levosimendan
CAS :Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.Formule :C14H12N6ODegré de pureté :99.32% - 99.91%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :280.28LY3009120
CAS :LY3009120 (DP-4978) is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. Phase 1.Formule :C23H29FN6ODegré de pureté :96.96% - ≥95%Couleur et forme :SolidMasse moléculaire :424.51PI-1840
CAS :PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formule :C22H26N4O3Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :394.47CaMKII-IN-1
CAS :CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM).Formule :C29H30ClN5O2SDegré de pureté :98.35%Couleur et forme :SolidMasse moléculaire :548.1Ref: TM-T14860
1mg52,00€2mg74,00€5mg119,00€10mg170,00€25mg354,00€50mg550,00€100mg792,00€1mL*10mM (DMSO)144,00€Brevilin A
CAS :Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formule :C20H26O5Degré de pureté :100% - 99.74%Couleur et forme :SolidMasse moléculaire :346.42Ref: TM-T4672
1mg96,00€5mg215,00€10mg369,00€25mg610,00€50mg840,00€100mg1.130,00€500mg2.308,00€1mL*10mM (DMSO)235,00€Pyriproxyfen
CAS :Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.Formule :C20H19NO3Degré de pureté :99.87%Couleur et forme :Solid CompactMasse moléculaire :321.37Naproxen
CAS :Naproxen ((S)-Naproxen) is a propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesicFormule :C14H14O3Degré de pureté :99.6% - 99.89%Couleur et forme :Crystals From Acetone-Hexane SolidMasse moléculaire :230.26ABT-751
CAS :ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Formule :C18H17N3O4SDegré de pureté :98.84% - 99.50%Couleur et forme :SolidMasse moléculaire :371.41Gartanin
CAS :Gartanin enhances androgen receptor degradation and has neuroprotective effects by boosting HO-1, AMPK, SIRT1, and PGC-1α pathways.Formule :C23H24O6Degré de pureté :99.64% - 99.85%Couleur et forme :SolidMasse moléculaire :396.43Cinobufagin
CAS :Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.Formule :C26H34O6Degré de pureté :97.77% - 98.16%Couleur et forme :SolidMasse moléculaire :442.54Ref: TM-T3432
1mg52,00€5mg96,00€10mg144,00€25mg215,00€50mg298,00€100mg464,00€500mg1.008,00€1mL*10mM (DMSO)96,00€
