Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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Enzalutamide
CAS :Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP).Formule :C21H16F4N4O2SDegré de pureté :100% - 99.7%Couleur et forme :SolidMasse moléculaire :464.44Ref: TM-T6002
5mg48,00€10mg56,00€25mg74,00€50mg96,00€100mg154,00€200mg187,00€500mg274,00€1mL*10mM (DMSO)52,00€A-484954
CAS :A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.Formule :C13H15N5O3Degré de pureté :97.47%Couleur et forme :SolidMasse moléculaire :289.29Ref: TM-TQ0137
1mg43,00€2mg56,00€5mg88,00€10mg144,00€25mg305,00€50mg543,00€100mg775,00€1mL*10mM (DMSO)103,00€Anti-LRRK2 Antibody (1C773)
Anti-LRRK2 Antibody (1C773) is an antibody targeting LRRK2. Anti-LRRK2 Antibody (1C773) can be used in ELISA, IHC.Couleur et forme :Odour Liquid(R)-(-)-Gossypol acetic acid
CAS :(R)-(-)-Gossypol acetic acid binds Bcl-2, Bcl-xL, Mcl-1 (Ki: 0.32, 0.48, 0.18 μM); no BIR3/BID inhibition. Phase 2.Formule :C30H30O8·C2H4O2Degré de pureté :96.73% - 99.5%Couleur et forme :SolidMasse moléculaire :578.61Ref: TM-T6396
1g1.359,00€2mg39,00€5mg57,00€10mg87,00€25mg170,00€50mg283,00€100mg464,00€500mg1.008,00€Niacin
CAS :Niacin is a water-soluble B vitamin with antihyperlipidemic effects, found in food and converted to niacinamide for coenzyme activity.Formule :C6H5NO2Degré de pureté :100% - 99.68%Couleur et forme :White Solid PowderMasse moléculaire :123.11CA-5f
CAS :CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.Formule :C24H24N2O3Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :388.46Glaucocalyxin B
CAS :Glaucocalyxin B is a diterpenoid isolated from Rabdosia japonica with anticancer and antitumor activity. It decreases the growth of HL-60 cells (IC50: 5.86 μM).Formule :C22H30O5Degré de pureté :99.13% - 99.13%Couleur et forme :SolidMasse moléculaire :374.47Hesperidin
CAS :Hesperidin (Cirantin), a citrus-fruit flavanone glycoside, boasts antioxidant, anti-inflammatory, anti-carcinogenic, and cardiovascular benefits.Formule :C28H34O15Degré de pureté :97.74% - 97.75%Couleur et forme :Fine Brownish Powder Solid PowderMasse moléculaire :610.56Ridaforolimus
CAS :Ridaforolimus (AP23573) 是亲脂性大环内酯类抗生素雷帕霉素的小分子非前药类似物,具有潜在的抗肿瘤活性。它是一种有效和选择性的 mTOR 抑制剂,在 HT-1080 细胞中抑制 S6 磷酸化的 IC50值为 0.2 nM。Formule :C53H84NO14PDegré de pureté :90.00% - 98.55%Couleur et forme :Off-White SolidMasse moléculaire :990.21Danshensu
CAS :Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.Formule :C9H10O5Degré de pureté :98.4% - 99.74%Couleur et forme :SolidMasse moléculaire :198.17Fulvestrant
CAS :Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30.Formule :C32H47F5O3SDegré de pureté :100% - 99.87%Couleur et forme :White PowderMasse moléculaire :606.77SB 242235
CAS :SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.Formule :C19H20FN5ODegré de pureté :99.13% - 99.68%Couleur et forme :SolidMasse moléculaire :353.39FAAH-IN-2
CAS :FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is a potent inhibitor of FAAH(fatty acid amide hydrolase).Formule :C15H11ClFN3O2Degré de pureté :99.18%Couleur et forme :Tan SolidMasse moléculaire :319.72Schaftoside
CAS :Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.Formule :C26H28O14Degré de pureté :100% - 99.32%Couleur et forme :SolidMasse moléculaire :564.49Ref: TM-T3898
1mg42,00€5mg85,00€10mg111,00€25mg210,00€50mg311,00€100mg467,00€200mg653,00€1mL*10mM (DMSO)95,00€Fluvastatin sodium
CAS :Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFormule :C24H25FNNaO4Degré de pureté :98.54% - 99.46%Couleur et forme :Light Yellow Solid PowderMasse moléculaire :433.45Myricetin
CAS :Myricetin (Cannabiscetin) is a natural flavonoid and MEK1 inhibitor. Myricetin has hypoglycemic and antioxidant activities. Cost-effective and quality-assured.Formule :C15H10O8Degré de pureté :97.92% - 99.85%Couleur et forme :Yellow Needles From Dilute Alcohol SolidMasse moléculaire :318.24Alisol A
CAS :Alisol A: induces autophagy, anti-cancer, inhibits HepG2, MDA-MB-231, MCF-7 cells.Formule :C30H50O5Degré de pureté :99.77% - 99.94%Couleur et forme :SolidMasse moléculaire :490.71SD 0006
CAS :SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.Formule :C20H20ClN5O2Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :397.86Ref: TM-T7276
2mg38,00€5mg58,00€10mg90,00€25mg145,00€50mg226,00€100mg338,00€200mg472,00€1mL*10mM (DMSO)65,00€Sertaconazole
CAS :Sertaconazole is a broad-spectrum antifungal.Formule :C20H15Cl3N2OSDegré de pureté :95.00%Couleur et forme :SolidMasse moléculaire :437.77Ref: TM-T50005
5mg58,00€10mg82,00€25mg126,00€50mg182,00€100mg273,00€200mg409,00€1mL*10mM (DMSO)84,00€Liensinine
CAS :1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.Formule :C37H42N2O6Degré de pureté :98.92% - 99.93%Couleur et forme :White-Like PowderMasse moléculaire :610.74Mycro 3
CAS :Mycro 3 is potent and selective for c-Myc in whole cell assays.Formule :C24H17ClF2N6O4Degré de pureté :97.87% - 99.51%Couleur et forme :SolidMasse moléculaire :526.88Ref: TM-T4367
1mg49,00€5mg99,00€10mg168,00€25mg335,00€50mg477,00€100mg662,00€200mg892,00€1mL*10mM (DMSO)116,00€PD168393
CAS :PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Formule :C17H13BrN4ODegré de pureté :99.13% - 99.7%Couleur et forme :SolidMasse moléculaire :369.22Ref: TM-T6932
1mg39,00€2mg49,00€5mg66,00€10mg89,00€25mg155,00€50mg222,00€100mg310,00€1mL*10mM (DMSO)56,00€AC-73
CAS :AC-73, an oral CD147 inhibitor, blocks ERK1/2/STAT3/MMP-2 pathway, reducing liver cancer progression and leukemia cell growth.Formule :C21H21NO2Degré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :319.4Ref: TM-T14091
1mg49,00€5mg97,00€10mg173,00€25mg305,00€50mg513,00€100mg909,00€500mg1.825,00€1mL*10mM (DMSO)108,00€EN6
CAS :EN6, a small molecule, activates autophagy by modifying ATP6V1A, inhibiting mTORC1 and enhancing lysosomal function to clear TDP-43 aggregates.Formule :C19H14F2N4O2Degré de pureté :95.16% - 97.04%Couleur et forme :SolidMasse moléculaire :368.34Ref: TM-T11191
1mg47,00€5mg88,00€10mg137,00€25mg205,00€50mg264,00€100mg400,00€500mg909,00€1mL*10mM (DMSO)70,00€Dilmapimod
CAS :Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.Formule :C23H19F3N4O3Degré de pureté :97.53%Couleur et forme :SolidMasse moléculaire :456.421-Monomyristin
CAS :1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterialFormule :C17H34O4Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :302.45IITZ-01
CAS :IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)Formule :C26H23FN8ODegré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :482.51Schisandrin B
CAS :Schisandrin B (Schisandrin B (Sch B)) has an antioxidant effect on rodent liver and heart.Formule :C23H28O6Degré de pureté :100% - 99.84%Couleur et forme :SolidMasse moléculaire :400.46Ref: TM-T2925
1mg42,00€5mg88,00€10mg127,00€25mg230,00€50mg414,00€100mg600,00€500mg1.254,00€1mL*10mM (DMSO)94,00€GNE-9605
CAS :GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).Formule :C17H20ClF4N7ODegré de pureté :98.55% - 98.75%Couleur et forme :SolidMasse moléculaire :449.83β-Lapachone
CAS :β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.Formule :C15H14O3Degré de pureté :99.64% - 99.85%Couleur et forme :SolidMasse moléculaire :242.27Ref: TM-T6407
5mg48,00€10mg60,00€25mg97,00€50mg185,00€100mg305,00€200mg460,00€500mg753,00€1mL*10mM (DMSO)63,00€Isotretinoin
CAS :Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promoteFormule :C20H28O2Degré de pureté :98.06% - 99.61%Couleur et forme :Reddish-Orange Plates From Isopropyl Alcohol (Ntp 1992)Masse moléculaire :300.44Dihydromyricetin
CAS :Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.Formule :C15H12O8Degré de pureté :96.68% - 98.13%Couleur et forme :SolidMasse moléculaire :320.25Neflamapimod
CAS :Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.Formule :C19H9Cl2F2N3OSDegré de pureté :99.02% - ≥95%Couleur et forme :SolidMasse moléculaire :436.26Cabazitaxel
CAS :Cabazitaxel (XRP6258) is a taxane used for castration-resistant metastatic prostate cancer post-docetaxel failure.Formule :C45H57NO14Degré de pureté :98% - 99.93%Couleur et forme :SolidMasse moléculaire :835.93LY2562175
CAS :LY2562175 is an effective and selective FXR agonist (EC50: 193 nM).Formule :C28H27Cl2N3O4Degré de pureté :99.16% - 99.78%Couleur et forme :SolidMasse moléculaire :540.44Ref: TM-T15806
1mg104,00€5mg227,00€10mg369,00€25mg740,00€50mg1.169,00€100mg1.568,00€200mg2.118,00€1mL*10mM (DMSO)269,00€Tizoxanide
CAS :Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Formule :C10H7N3O4SDegré de pureté :98.89% - 99.28%Couleur et forme :SolidMasse moléculaire :265.25Ambroxol
CAS :Ambroxol treats respiratory diseases by thinning mucus. Active in Mucosolvan, it enhances mucus clearance and protects lungs.Formule :C13H18Br2N2ODegré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :378.1Gimeracil
CAS :Gimeracil (Gimestat) is a competitive, reversible inhibitor of dihydropyrimidine dehydrogenase.Formule :C5H4ClNO2Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :145.54Bortezomib
CAS :Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formule :C19H25BN4O4Degré de pureté :100% - 99.97%Couleur et forme :Yellow SolidMasse moléculaire :384.24Ref: TM-T2399
5mg52,00€10mg64,00€25mg80,00€50mg96,00€100mg144,00€200mg225,00€500mg373,00€1mL*10mM (DMSO)52,00€Pogostone
CAS :Pogostone: anti-bacterial/fungal, blocks T-cells, modulates cytokines, protects against gastric ulcers, boosts antioxidants/PGE2/NP-SH.Formule :C12H16O4Degré de pureté :98.46% - 99.03%Couleur et forme :SolidMasse moléculaire :224.25Rosuvastatin calcium
CAS :Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemicFormule :(C22H27FN3O6S)CaDegré de pureté :98.85% - 99.68%Couleur et forme :White To Off-White Crystalline SolidMasse moléculaire :1001.14SKF-96365 hydrochloride
CAS :SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormule :C22H27ClN2O3Degré de pureté :99.48% - 99.85%Couleur et forme :SolidMasse moléculaire :402.91Ref: TM-T2170
5mg57,00€10mg86,00€25mg138,00€50mg243,00€100mg470,00€200mg717,00€500mg1.111,00€1mL*10mM (DMSO)63,00€Hydroxychloroquine
CAS :HCQ, an anti-malarial, may induce cancer cell death and is being explored for COVID-19.Formule :C18H26ClN3ODegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :335.87Cilostazol
CAS :Cilostazol (OPC 21) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of cilostazol is as a Phosphodiesterase 3 Inhibitor.Formule :C20H27N5O2Degré de pureté :99.58% - 99.90%Couleur et forme :Off-White SolidMasse moléculaire :369.46Gambogic Acid
CAS :Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases.Formule :C38H44O8Degré de pureté :97.16% - 98.67%Couleur et forme :SolidMasse moléculaire :628.75Ref: TM-T6185
2mg39,00€5mg55,00€10mg77,00€25mg111,00€50mg160,00€100mg227,00€500mg560,00€1mL*10mM (DMSO)88,00€Sofalcone
CAS :Sofalcone (SU-88), a gastric antiulcer agent in clinical use, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.Formule :C27H30O6Degré de pureté :97.55%Couleur et forme :SolidMasse moléculaire :450.52SB 202190
CAS :SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.Formule :C20H14FN3ODegré de pureté :98% - 99.84%Couleur et forme :Pale YellowMasse moléculaire :331.34Diazoxide
CAS :Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies.Formule :C8H7ClN2O2SDegré de pureté :99% - 99.83%Couleur et forme :SolidMasse moléculaire :230.67Nitazoxanide
CAS :Nitazoxanide (NSC-697855) is a synthetic benzamide antiprotozoal; it disrupts pyruvate electron transfer reactions.Formule :C12H9N3O5SDegré de pureté :97.20% - 99.53%Couleur et forme :SolidMasse moléculaire :307.28Ref: TM-T1546
1g750,00€5mg35,00€10mg51,00€25mg90,00€50mg139,00€100mg207,00€200mg311,00€500mg520,00€1mL*10mM (DMSO)55,00€Belinostat
CAS :Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.Formule :C15H14N2O4SDegré de pureté :100% - 99.75%Couleur et forme :SolidMasse moléculaire :318.35Ref: TM-T8517
5mg48,00€10mg69,00€25mg97,00€50mg144,00€100mg207,00€200mg306,00€500mg518,00€1mL*10mM (DMSO)63,00€AS1842856
CAS :AS1842856 is a Foxo1 inhibitor that blocks the transcriptional activity of Foxo1. AS1842856 has autophagy inhibitory activity. Cost-effective and quality-assured.Formule :C18H22FN3O3Degré de pureté :100% - 99.56%Couleur et forme :SolidMasse moléculaire :347.38SP-8356
CAS :SP-8356 is a potent, orally active inhibitor of cluster of differentiation 147 (CD147) with anti-atherosclerotic effects.Formule :C18H20O4Degré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :300.35Ref: TM-T12981
1mg70,00€5mg156,00€10mg238,00€25mg449,00€50mg610,00€100mg815,00€200mg1.103,00€1mL*10mM (DMSO)170,00€Megestrol acetate
CAS :Megestrol acetate (BDH1298) is an oral progestogen with anti-androgenic properties, used for endometrial and breast cancer, anorexia, and cachexia.Formule :C24H32O4Degré de pureté :99.46%Couleur et forme :Crystalline SolidMasse moléculaire :384.51GANT 61
CAS :GANT 61 (GANT61) is an inhibitor for Gli1 and Gli2.Formule :C27H35N5Degré de pureté :100% - ≥95%Couleur et forme :SolidMasse moléculaire :429.6TTNPB
CAS :TTNPB (Ro 13-7410,AGN-191183), a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM),Formule :C24H28O2Degré de pureté :99.55%Couleur et forme :White SolidMasse moléculaire :348.48Ref: TM-T1288
2mg39,00€5mg57,00€10mg87,00€25mg162,00€50mg306,00€100mg464,00€500mg1.008,00€1mL*10mM (DMSO)59,00€Valproic acid sodium salt
CAS :Sodium valproate is an anti-epileptic, boosting brain GABA levels and possibly affecting potassium channels for membrane stability.Formule :C8H15NaO2Degré de pureté :99% - 99.78%Couleur et forme :White PowderMasse moléculaire :166.2Dinoprost tromethamine salt
CAS :Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.Formule :C24H45NO8Degré de pureté :99.73%Couleur et forme :Natural Form Crystals SolidMasse moléculaire :475.62BIX-01294 trihydrochloride
CAS :BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.Formule :C28H38N6O2·3HClDegré de pureté :99.41% - 99.95%Couleur et forme :SolidMasse moléculaire :600.02Ref: TM-T1959
1mg44,00€2mg55,00€5mg71,00€10mg107,00€25mg192,00€50mg274,00€100mg492,00€500mg1.103,00€1mL*10mM (DMSO)139,00€Salicylic acid
CAS :Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.Formule :C7H6O3Degré de pureté :98.04% - 98.83%Couleur et forme :White Solid PowderMasse moléculaire :138.12CFTR corrector 2
CAS :CFTR corrector 2 (FDL169) is a novel and potent CFTR corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.Formule :C27H23FN4O4Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :486.49Ref: TM-T5312
2mg39,00€5mg58,00€10mg85,00€25mg156,00€50mg226,00€100mg335,00€200mg469,00€1mL*10mM (DMSO)63,00€LRRK2-IN-7
CAS :LRRK2-IN-7: potent, selective CNS-active LRRK2 inhibitor, IC50 0.9 nM, >1000x selectivity vs kinases/channels/CYPs.Formule :C24H26N6ODegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :414.5BX795
CAS :BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.Formule :C23H26IN7O2SDegré de pureté :98% - 99.57%Couleur et forme :SolidMasse moléculaire :591.47Ref: TM-T1830
5mg59,00€10mg97,00€25mg210,00€50mg343,00€100mg513,00€200mg740,00€500mg1.121,00€1mL*10mM (DMSO)88,00€Apocynin
CAS :Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).Formule :C9H10O3Degré de pureté :99.71% - 99.98%Couleur et forme :Yellowish To Brown PowderMasse moléculaire :166.17Trametinib
CAS :Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.Formule :C26H23FIN5O4Degré de pureté :98% - 99.88%Couleur et forme :SolidMasse moléculaire :615.39GSK2578215A
CAS :GSK2578215A is a potent and selective LRRK2 kinase inhibitor.Formule :C24H18FN3O2Degré de pureté :97.93% - 99.94%Couleur et forme :SolidMasse moléculaire :399.42Indomethacin farnesil
CAS :Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug.Formule :C34H40ClNO4Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :562.14Clarithromycin
CAS :Clarithromycin (A-56268), a macrolide antibiotic, inhibits Cytochrome P450 3A4 and P-Glycoprotein.Formule :C38H69NO13Degré de pureté :99.89% - 99.89%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :747.95Dioscin
CAS :Dioscin (Collettiside III) is a saponin with antitumor activities.Formule :C45H72O16Degré de pureté :98.35% - 99.85%Couleur et forme :SolidMasse moléculaire :869.04Torin 1
CAS :Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.Formule :C35H28F3N5O2Degré de pureté :98.3% - 99.38%Couleur et forme :SolidMasse moléculaire :607.62AT9283
CAS :AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).Formule :C19H23N7O2Degré de pureté :99.83% - 99.98%Couleur et forme :SolidMasse moléculaire :381.43Ref: TM-T3068
1mg47,00€2mg60,00€5mg95,00€10mg170,00€25mg299,00€50mg499,00€100mg723,00€1mL*10mM (DMSO)97,00€LC3B recruiter 2
CAS :LC3B recruiter 2 (34R) is an LC3B recruiting agent incorporated into the autophagy-lysosome pathway degradation system (ATTEC, Autophagy-Tethering Compounds), with a direct binding affinity for LC3B. It connects via a linker to the CDK9 inhibitor SNS-032, creating an ATTEC capable of targeting and degrading the CDK9 and Cyclin T1 complex, while also inhibiting them. Consequently, LC3B recruiter 2 exerts its function through an LC3B-dependent autophagy-lysosome pathway, interfering with the cancer cell cycle progression, thereby demonstrating antitumor activity.Formule :C10H9ClN2O2Couleur et forme :SolidMasse moléculaire :224.644Pifithrin-μ
CAS :Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.Formule :C8H7NO2SDegré de pureté :99.33% - 99.79%Couleur et forme :SolidMasse moléculaire :181.21Flavopiridol hydrochloride
CAS :Flavopiridol hydrochloride (MDL 107826A), an inhibitor of cyclin-dependent kinase, is a synthetic N-methylpiperidinyl chlorophenyl flavone compound.Formule :C21H21Cl2NO5Degré de pureté :98.87% - 99.88%Couleur et forme :SolidMasse moléculaire :438.3Paris saponin VII
CAS :Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.Formule :C51H82O21Degré de pureté :99.51% - 99.63%Couleur et forme :SolidMasse moléculaire :1031.18Pexmetinib
CAS :Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.Formule :C31H33FN6O3Degré de pureté :98.41% - 99.66%Couleur et forme :SolidMasse moléculaire :556.63Ref: TM-T6934
1mg47,00€5mg97,00€10mg139,00€25mg271,00€50mg435,00€100mg567,00€200mg810,00€1mL*10mM (DMSO)118,00€Nur77 modulator 1
CAS :Nur77 modulator 1: binds at 3.58 μM, boosts expression, alters location, triggers ER stress/autophagy, induces apoptosis, and fights hepatoma.Formule :C28H25N5O2SDegré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :495.6Ref: TM-T40130
1mg96,00€5mg227,00€10mg376,00€25mg620,00€50mg847,00€100mg1.169,00€1mL*10mM (DMSO)245,00€Aspirin
CAS :Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.Formule :C9H8O4Degré de pureté :99.78% - 99.91%Couleur et forme :White Solid CrystallineMasse moléculaire :180.16Degrasyn
CAS :Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.Formule :C19H18BrN3ODegré de pureté :98.32% - 99.98%Couleur et forme :SolidMasse moléculaire :384.27Ref: TM-T6300
2mg44,00€5mg64,00€10mg97,00€25mg198,00€50mg340,00€100mg532,00€200mg747,00€1mL*10mM (DMSO)69,00€Bilobalide
CAS :Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.Formule :C15H18O8Degré de pureté :98.27% - 99.91%Couleur et forme :White SolidMasse moléculaire :326.3Bigelovin
CAS :Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.Formule :C17H20O5Degré de pureté :99.72% - 99.72%Couleur et forme :SolidMasse moléculaire :304.34Ref: TM-TN6735
1mg92,00€5mg216,00€10mg283,00€25mg490,00€50mg700,00€100mg938,00€1mL*10mM (DMSO)215,00€Br-DAPI
CAS :IST5-002 (N6-Benzyladenosine-5'-phosphate) is a Stat5a/b inhibitor with anticancer activity and is used in cancer research.Formule :C16H14BrN5Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :356.22Apigenin
CAS :Apigenin (NSC 83244) is an aromatic oil extracted from the flowers or leaves of the daisy-like plants.Formule :C15H10O5Degré de pureté :97.95% - 99.66%Couleur et forme :Yellow Needles From Aqueous Pyridine SolidMasse moléculaire :270.24Divalproex Sodium
CAS :Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted byFormule :C8H16O2·C8H15O2·NaDegré de pureté :99.84%Couleur et forme :A White Powder With A Characteristic OdorMasse moléculaire :310.41Ref: TM-T6474
10mg39,00€25mg55,00€50mg79,00€100mg116,00€200mg188,00€500mg335,00€1mL*10mM (DMSO)55,00€Torin 2
CAS :Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.Formule :C24H15F3N4ODegré de pureté :98.31% - 99.32%Couleur et forme :SolidMasse moléculaire :432.4Ginkgetin
CAS :Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.Formule :C32H22O10Degré de pureté :98.91% - 99.94%Couleur et forme :SolidMasse moléculaire :566.51Ref: TM-T4S2126
1mg58,00€5mg118,00€10mg172,00€25mg278,00€50mg411,00€100mg607,00€200mg847,00€1mL*10mM (DMSO)153,00€Maprotiline hydrochloride
CAS :Maprotiline hydrochloride (Psymion) is a tetracyclic antidepressant akin to tricyclics with similar side effects.Formule :C20H24ClNDegré de pureté :99.68% - 99.84%Couleur et forme :White PowderMasse moléculaire :313.864Hydroxyurea
CAS :Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.Formule :CH4N2O2Degré de pureté :99.85% - 99.92%Couleur et forme :SolidMasse moléculaire :76.05Carbamazepine
CAS :Carbamazepine: a tricyclic with anticonvulsant and analgesic effects, treats trigeminal neuralgia.Formule :C15H12N2ODegré de pureté :99.79% - 99.88%Couleur et forme :SolidMasse moléculaire :236.27Saquinavir mesylate
CAS :Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapyFormule :C39H54N6O8SDegré de pureté :99.19%Couleur et forme :White Or Pale Yellow PowderMasse moléculaire :766.9Imatinib
CAS :Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormule :C29H31N7ODegré de pureté :100% - 99.94%Couleur et forme :Off White PowderMasse moléculaire :493.6Polyphyllin I
CAS :Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,Formule :C44H70O16Degré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :855.02Troglitazone
CAS :Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Formule :C24H27NO5SDegré de pureté :98% - 99.62%Couleur et forme :Yellow SolidMasse moléculaire :441.54Ref: TM-T3170
2mg42,00€5mg62,00€10mg88,00€25mg172,00€50mg305,00€100mg558,00€500mg1.169,00€1mL*10mM (DMSO)85,00€Liensinine diperchlorate
CAS :Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus.Formule :C37H44Cl2N2O14Degré de pureté :99.8% - ≥95%Couleur et forme :SolidMasse moléculaire :811.67Tripterin
CAS :Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.Formule :C29H38O4Degré de pureté :98.56% - 99.8%Couleur et forme :Red Crystalline PowderMasse moléculaire :450.61LYN-1604 dihydrochloride
CAS :LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.Formule :C33H45Cl4N3O2Degré de pureté :98.95% - 99.80%Couleur et forme :SolidMasse moléculaire :657.54Ref: TM-T8808L
1mg35,00€5mg78,00€10mg117,00€25mg212,00€50mg316,00€100mg447,00€200mg628,00€1mL*10mM (DMSO)101,00€BIA 10-2474
CAS :BIA 10-2474 is a long-acting reversible inhibitor of FAAH that increases levels of the neurotransmitter anandamide in the nervous system.Formule :C16H20N4O2Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :300.36Xylitol
CAS :Xylitol (Ribitol) is a five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group.Formule :C5H12O5Degré de pureté :99.89% - 99.96%Couleur et forme :White Solid PowderMasse moléculaire :152.15Ivacaftor
CAS :Ivacaftor (VX-770) (VX-770) is a potentiator of CFTR targeting G551D-CFTR (EC50: 100 nM) and F508del-CFTR (EC50: 25 nM) in Fisher rat thyroid cells,Formule :C24H28N2O3Degré de pureté :99% - 99.98%Couleur et forme :SolidMasse moléculaire :392.49Ref: TM-T2588
1mg38,00€5mg81,00€10mg127,00€25mg205,00€50mg304,00€100mg455,00€500mg998,00€1mL*10mM (DMSO)88,00€MDK-6983
CAS :MDK-6983 (MDK-6983) is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.Formule :C22H18Cl2N2O3Degré de pureté :97.55%Couleur et forme :SolidMasse moléculaire :429.3Ref: TM-T28001
1mg115,00€5mg249,00€10mg368,00€25mg562,00€50mg787,00€100mg1.054,00€500mgÀ demander1mL*10mM (DMSO)284,00€Dorsomorphin dihydrochloride
CAS :Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity onFormule :C24H25N5O·2HClDegré de pureté :97.74% - 99.89%Couleur et forme :SolidMasse moléculaire :472.41Ref: TM-T6146
2mg35,00€5mg51,00€10mg70,00€25mg135,00€50mg235,00€100mg424,00€500mg938,00€1mL*10mM (DMSO)57,00€
