Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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AZD 6482
CAS :AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.Formule :C22H24N4O4Degré de pureté :99.79% - 99.95%Couleur et forme :SolidMasse moléculaire :408.45ML-SA5
CAS :ML-SA5 is a MCOLN1 agonist that blocks autophagic flux by disrupting fusion between autophagosomes and lysosomes.Cost-effective and quality-assured.Formule :C19H24ClN3O4S2Degré de pureté :100.00% - 99.16%Couleur et forme :SoildMasse moléculaire :457.99IU1
CAS :IU1 是一种可逆的特异性人类 USP14 蛋白酶体抑制剂,可以穿透细胞,IC50为 4.7 μM。Formule :C18H21FN2ODegré de pureté :98% - 99.30%Couleur et forme :SolidMasse moléculaire :300.37Pitavastatin calcium
CAS :Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.Formule :C50H46CaF2N2O8Degré de pureté :100% - 99.49%Couleur et forme :White To Off-White PowderMasse moléculaire :880.98Dapivirine
CAS :Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.Formule :C20H19N5Degré de pureté :98% - 99.77%Couleur et forme :SolidMasse moléculaire :329.4Acumapimod
CAS :Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).Formule :C22H19N5O2Degré de pureté :≥95%Couleur et forme :SolidMasse moléculaire :385.42Tazarotene
CAS :Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.Formule :C21H21NO2SDegré de pureté :97.01% - 99.14%Couleur et forme :White SolidMasse moléculaire :351.46Ref: TM-T6696
5mg38,00€10mg49,00€25mg88,00€50mg147,00€100mg256,00€200mg334,00€500mg563,00€1mL*10mM (DMSO)55,00€BI-D1870
CAS :BI-D1870 is a highly specific, blood-brain-permeable, and ATP-competitive inhibitor of the N-terminal AGC kinase domain of RSK.Cost-effective and quality-assured.Formule :C19H23F2N5O2Degré de pureté :98.51% - 99.43%Couleur et forme :SolidMasse moléculaire :391.42Ref: TM-T6171
1mg52,00€2mg78,00€5mg137,00€10mg207,00€25mg335,00€50mg472,00€100mg658,00€500mg1.378,00€1mL*10mM (DMSO)117,00€Mevastatin
CAS :Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.Formule :C23H34O5Degré de pureté :99.12%Couleur et forme :White-Yellowish To Yellow Powder Solid PowderMasse moléculaire :390.51Tezacaftor
CAS :Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.Formule :C26H27F3N2O6Degré de pureté :100% - 99.69%Couleur et forme :SolidMasse moléculaire :520.5Ref: TM-T2263
1mg40,00€2mg52,00€5mg82,00€10mg123,00€25mg212,00€50mg343,00€100mg505,00€1mL*10mM (DMSO)88,00€Albendazole
CAS :Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.Formule :C12H15N3O2SDegré de pureté :98.21% - 98.76%Couleur et forme :Colorless Crystals SolidMasse moléculaire :265.33Entrectinib
CAS :Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.Formule :C31H34F2N6O2Degré de pureté :98.03% - 99.61%Couleur et forme :SolidMasse moléculaire :560.64Ref: TM-T3678
2mg42,00€5mg59,00€10mg88,00€25mg111,00€50mg168,00€100mg283,00€500mg692,00€1mL*10mM (DMSO)69,00€PI-103
CAS :PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Formule :C19H16N4O3Degré de pureté :96.59% - 99.3%Couleur et forme :SolidMasse moléculaire :348.36Salinomycin sodium salt
CAS :Salinomycin sodium salt (Sodium salinomycin), an antibiotic potassium ionophore, is an effective inhibitor of Wnt/β-catenin signaling.Formule :C42H69NaO11Degré de pureté :98.76% - 99.11%Couleur et forme :White Or Light Yellow Crystalline Powder With Special SmelMasse moléculaire :772.98Resveratrol analog 1
CAS :Resveratrol analog 1 is a natural product analog of resveratrol, which has more significant anti-leukemic activity than resveratrol.Formule :C14H11FO2Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :230.23PRIMA-1
CAS :PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formule :C9H15NO3Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :185.22Ref: TM-T6954
5mg51,00€10mg73,00€25mg140,00€50mg207,00€100mg368,00€200mg547,00€500mg877,00€1mL*10mM (DMSO)57,00€C646
CAS :C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).Formule :C24H19N3O6Degré de pureté :98% - 99.21%Couleur et forme :SolidMasse moléculaire :445.42Bromhexine hydrochloride
CAS :Bromhexine hydrochloride (Bisolvon) is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.Formule :C14H21Br2ClN2Degré de pureté :99.98%Couleur et forme :White SolidMasse moléculaire :412.59ALLO-1
CAS :ALLO-1, vital for autophagy, aids in engulfing paternal organelles by binding to worm LC3, LGG-1, via its LIR motif.Formule :C17H15ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :314.77Pemetrexed
CAS :Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).Formule :C20H21N5O6Degré de pureté :98.1% - 99.92%Couleur et forme :Similar To White PowderMasse moléculaire :427.413,3'-Diindolylmethane
CAS :3,3'-Diindolylmethane (DIM), a small molecule compound, is a proposed Y preventive agent.Formule :C17H14N2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :246.31Peretinoin
CAS :Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR.Formule :C20H30O2Degré de pureté :97.23%Couleur et forme :SolidMasse moléculaire :302.45Ref: TM-TQ0064
1mg40,00€2mg51,00€5mg88,00€10mg126,00€25mg230,00€50mg401,00€100mg597,00€500mg1.283,00€1mL*10mM (DMSO)87,00€Tenovin-1
CAS :Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.Formule :C20H23N3O2SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :369.48Sevelamer hydrochloride
CAS :Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorptionFormule :(C3H7N·C3H5ClO·HCl)xDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :186.08NS1643
CAS :NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.Formule :C15H10F6N2O3Degré de pureté :98.37% - 99%Couleur et forme :SolidMasse moléculaire :380.24Thioridazine hydrochloride
CAS :Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Formule :C21H27ClN2S2Degré de pureté :99.55% - 99.55%Couleur et forme :White To Off-White SolidMasse moléculaire :407.04Luteolin
CAS :Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor.Formule :C15H10O6Degré de pureté :96.61% - 98%Couleur et forme :SolidMasse moléculaire :286.24Bakuchiol
CAS :Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.Formule :C18H24ODegré de pureté :98.69% - 99.47%Couleur et forme :Brownish Yellow Liquid ViscousMasse moléculaire :256.38Pamapimod
CAS :Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.Formule :C19H20F2N4O4Degré de pureté :97.63% - 99.99%Couleur et forme :SolidMasse moléculaire :406.38Ref: TM-T6927
1mg56,00€5mg119,00€10mg187,00€25mg378,00€50mg605,00€100mg852,00€500mg1.700,00€1mL*10mM (DMSO)131,00€XRK3F2
CAS :XRK3F2 inhibits p62-ZZ, counters MM's Runx2 suppression in vitro, and prompts bone growth and remodeling in vivo with tumors.Formule :C23H24ClF2NO3Degré de pureté :98.75% - 98.91%Couleur et forme :SolidMasse moléculaire :435.89STF-31
CAS :STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.Formule :C23H25N3O3SDegré de pureté :99.55% - 99.98%Couleur et forme :SolidMasse moléculaire :423.53Ref: TM-T2363
1mg38,00€2mg50,00€5mg81,00€10mg113,00€25mg230,00€50mg437,00€100mg640,00€500mg1.349,00€1mL*10mM (DMSO)106,00€Reserpine
CAS :Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.Formule :C33H40N2O9Degré de pureté :98.85% - 99.81%Couleur et forme :White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Masse moléculaire :608.68Nifedipine
CAS :Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent.Formule :C17H18N2O6Degré de pureté :99.39% - 99.49%Couleur et forme :Yellow Crystals Physical Description Odorless Yellow Crystals Or Powder Tasteless (Ntp 1992)Masse moléculaire :346.33Vinorelbine ditartrate
CAS :Vinorelbine ditartrate (KW-2307) is a natural alkaloid and an anti-mitotic agent. Vinorelbine ditartrate has anti-tumor activity. Cost-effective and quality-assured.Formule :C45H54N4O8·2C4H6O6Degré de pureté :98% - 99.86%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :1079.11Tomatidine
CAS :Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.Formule :C27H45NO2Degré de pureté :98.38% - 99.98%Couleur et forme :SolidMasse moléculaire :415.65Proflavine Hemisulfate
CAS :Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt of proflavine, an acridine-derived fluorescent contrast and disinfectant agent.Formule :C13H12N3O2S0Degré de pureté :99.55%Couleur et forme :Orange To Red PowderMasse moléculaire :258.29CGI-1746
CAS :CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.Formule :C34H37N5O4Degré de pureté :97.69% - 97.88%Couleur et forme :SolidMasse moléculaire :579.69Aumitin
CAS :Aumitin inhibits autophagy (IC50: 0.12-0.24μM), targets complex I, and blocks mitochondrial respiration.Formule :C24H20ClN5ODegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :429.9Ref: TM-T14346
1mg65,00€5mg150,00€10mg219,00€25mg395,00€50mg552,00€100mg775,00€200mg1.026,00€1mL*10mM (DMSO)164,00€PD98059
CAS :PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formule :C16H13NO3Degré de pureté :100% - 99.66%Couleur et forme :Yellow SolidMasse moléculaire :267.28Ref: TM-T2623
5mg40,00€10mg52,00€25mg82,00€50mg106,00€100mg177,00€200mg264,00€500mg444,00€1mL*10mM (DMSO)58,00€NSC 185058
CAS :NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.Formule :C11H9N3SDegré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :215.27Tubastatin A Hydrochloride
CAS :Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).Formule :C20H21N3O2·HClDegré de pureté :97.24% - 99.15%Couleur et forme :SolidMasse moléculaire :371.86Ezetimibe
CAS :Ezetimibe (SCH 58235) is a Dietary Cholesterol Absorption Inhibitor. The physiologic effect of ezetimibe is by means of Decreased Cholesterol Absorption.Formule :C24H21F2NO3Degré de pureté :97.28% - 99.97%Couleur et forme :SolidMasse moléculaire :409.43Ref: TM-T1593
1g283,00€10mg48,00€25mg62,00€50mg77,00€100mg87,00€200mg125,00€500mg197,00€1mL*10mM (DMSO)55,00€Latrepirdine dihydrochloride
CAS :Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formule :C21H25N3·2HClDegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :392.37Irinotecan
CAS :Irinotecan (CPT-11), a camptothecin derivative, inhibits topoisomerase I, used for colorectal cancer treatment.Formule :C33H38N4O6Degré de pureté :100% - 99.92%Couleur et forme :SolidMasse moléculaire :586.68Indole-3-Glyoxylyl Chloride
CAS :Indole-3-glyoxylyl chloride (3-Indoleglyoxylyl chloride) can be used in chemical synthesis, such as bisindolylmaleimide.Formule :C10H6ClNO2Degré de pureté :99.72%Couleur et forme :Yellow To Orange Powder Or CrystalsMasse moléculaire :207.61Ref: TM-T0618
1mg97,00€2mg145,00€5mg235,00€10mg394,00€25mg825,00€50mg1.349,00€100mg2.175,00€1mL*10mM (DMSO)379,00€Urolithin A
CAS :Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.Formule :C13H8O4Degré de pureté :99.14% - 99.66%Couleur et forme :SolidMasse moléculaire :228.2Ref: TM-T7174
5mg49,00€10mg72,00€25mg130,00€50mg187,00€100mg320,00€200mg472,00€500mg753,00€1mL*10mM (DMSO)50,00€Peiminine
CAS :1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.Formule :C27H43NO3Degré de pureté :99.52% - ≥95%Couleur et forme :White PowderMasse moléculaire :429.64PF-543 hydrochloride
CAS :PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2Formule :C27H32ClNO4SDegré de pureté :98.90% - 99.93%Couleur et forme :SolidMasse moléculaire :502.1SBI-0640756
CAS :SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.Formule :C23H14ClFN2O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :404.82Ref: TM-T5173
1mg39,00€5mg87,00€10mg140,00€25mg271,00€50mg386,00€100mg540,00€200mg735,00€1mL*10mM (DMSO)93,00€Topotecan hydrochloride
CAS :Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.Formule :C23H24ClN3O5Degré de pureté :97.88% - 98.71%Couleur et forme :White Crystalline SolidMasse moléculaire :457.92Ref: TM-T1174
1g512,00€5mg35,00€10mg51,00€25mg80,00€50mg107,00€100mg144,00€500mg344,00€1mL*10mM (DMSO)55,00€AL 8697
CAS :AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.Formule :C21H21F3N4ODegré de pureté :98.96% - 99.26%Couleur et forme :SolidMasse moléculaire :402.41Ref: TM-T10277
1mg70,00€5mg145,00€10mg207,00€25mg348,00€50mg495,00€100mg678,00€500mgÀ demander1mL*10mM (DMSO)169,00€Pterostilbene
CAS :Pterostilbene is extracted from Pterocarpus indicus.Formule :C16H16O3Degré de pureté :99.20%Couleur et forme :Off-White Crystalline PowderMasse moléculaire :256.3Lapatinib ditosylate monohydrate
CAS :Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.Formule :C29H26ClFN4O4S·2(C7H8O3S)·H2ODegré de pureté :98% - 99.41%Couleur et forme :Colourless To Light-Yellow CrystalMasse moléculaire :943.47KM11060
CAS :KM11060 is a novel corrector of the F508del-CFTR trafficking defect, Correcting F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasmaFormule :C19H17Cl2N3O2SDegré de pureté :98.86%Couleur et forme :SolidMasse moléculaire :422.33Salvianolic acid B
CAS :Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia miltiorrhiza extract with antiplatelet aggregation and antithrombotic effects.Formule :C36H30O16Degré de pureté :99.76% - 99.86%Couleur et forme :Yellow SolidMasse moléculaire :718.61YM-201636
CAS :YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.Formule :C25H21N7O3Degré de pureté :93.28% - 98.3%Couleur et forme :SolidMasse moléculaire :467.48Ref: TM-T6110
1mg48,00€2mg64,00€5mg96,00€10mg173,00€25mg359,00€50mg562,00€100mg802,00€500mg1.644,00€1mL*10mM (DMSO)97,00€Ambroxol hydrochloride
CAS :Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract.Formule :C13H18Br2N2O·HClDegré de pureté :99.70%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :414.56Dehydrocorydaline
CAS :1.Formule :C22H24NO4Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :366.43Ref: TM-T5S2358
1mg57,00€2mg81,00€5mg111,00€10mg160,00€25mg263,00€50mg378,00€100mg558,00€200mg797,00€1mL*10mM (DMSO)123,00€PF-06447475
CAS :PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.Formule :C17H15N5ODegré de pureté :98.61% - 99.62%Couleur et forme :SolidMasse moléculaire :305.33DC661
CAS :DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.Formule :C31H39Cl2N5Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :552.58Ref: TM-T5538
1mg80,00€2mg105,00€5mg188,00€10mg319,00€25mg545,00€50mg780,00€100mg1.074,00€1mL*10mM (DMSO)230,00€Olanzapine
CAS :Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.Formule :C17H20N4SDegré de pureté :100% - ≥95%Couleur et forme :Yellowish Crystalline PowderMasse moléculaire :312.43sbp-7455
CAS :SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.Formule :C16H17F3N4O2Degré de pureté :97.90% - 99.03%Couleur et forme :SolidMasse moléculaire :354.33Doxorubicin
CAS :Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.Formule :C27H29NO11Degré de pureté :99.31%Couleur et forme :Red Crystalline Solid SolidMasse moléculaire :543.52RITA
CAS :RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.Formule :C14H12O3S2Degré de pureté :97.76% - 98.85%Couleur et forme :SolidMasse moléculaire :292.37Ref: TM-T1798
1mg35,00€2mg46,00€5mg66,00€10mg96,00€25mg188,00€50mg344,00€100mg509,00€200mg715,00€500mg1.093,00€1mL*10mM (DMSO)89,00€5-Azacytidine
CAS :5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formule :C8H12N4O5Degré de pureté :99.31% - 99.79%Couleur et forme :Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Masse moléculaire :244.2(-)-Epigallocatechin
CAS :(-)-Epigallocatechin, the predominant flavonoid in green tea, possesses the unique ability to attach to unfolded native polypeptides, thereby inhibiting theirFormule :C15H14O7Degré de pureté :98.83% - 99.76%Couleur et forme :White PowderMasse moléculaire :306.27OSI-027
CAS :OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.Formule :C21H22N6O3Degré de pureté :97.42%Couleur et forme :SolidMasse moléculaire :406.44Ref: TM-T6319
1mg42,00€2mg52,00€5mg86,00€10mg138,00€25mg248,00€50mg389,00€100mg567,00€1mL*10mM (DMSO)88,00€FAAH inhibitor 1
CAS :FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.Formule :C24H23N3O3S3Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :497.65Ref: TM-T11256
1mg52,00€5mg116,00€10mg182,00€25mg306,00€50mg442,00€100mg620,00€200mg835,00€1mL*10mM (DMSO)128,00€MW-150
CAS :MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.Formule :C24H23N5Degré de pureté :97.35% - 99.27%Couleur et forme :SolidMasse moléculaire :381.47Ref: TM-T5494
1mg39,00€5mg96,00€10mg153,00€25mg305,00€50mg454,00€100mg655,00€500mg1.406,00€1mL*10mM (DMSO)114,00€Rosiglitazone maleate
CAS :Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.Formule :C22H23N3O7SDegré de pureté :99.33% - 99.51%Couleur et forme :Off-White SolidMasse moléculaire :473.5Pictilisib dimethanesulfonate
CAS :Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) andFormule :C25H35N7O9S4Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :705.85Bicyclol
CAS :Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.Formule :C19H18O9Degré de pureté :99.48% - 99.88%Couleur et forme :SolidMasse moléculaire :390.34Ref: TM-T4121
5mg63,00€10mg88,00€25mg192,00€50mg354,00€100mg518,00€500mg1.111,00€1mL*10mM (DMSO)63,00€Vismodegib
CAS :Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).Formule :C19H14Cl2N2O3SDegré de pureté :98% - 99.99%Couleur et forme :SolidMasse moléculaire :421.3URMC-099
CAS :URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 - MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formule :C27H27N5Degré de pureté :98.43% - 99.32%Couleur et forme :SolidMasse moléculaire :421.54Pinosylvin
CAS :Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.Formule :C14H12O2Degré de pureté :99.89% - 99.91%Couleur et forme :SolidMasse moléculaire :212.24Deferoxamine Mesylate
CAS :Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.Formule :C26H52N6O11SDegré de pureté :94.68% - 99.80%Couleur et forme :SolidMasse moléculaire :656.79Paclitaxel
CAS :Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.Formule :C47H51NO14Degré de pureté :98% - 99.92%Couleur et forme :White PowderMasse moléculaire :853.91Danthron
CAS :Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.Formule :C14H8O4Degré de pureté :99.97%Couleur et forme :Red Or Red-Yellow Needles Or Leaves (From Alcohol) Physical Description Orange Crystalline Powder Almost Odorless And Tasteless (Ntp 1992)Masse moléculaire :240.21PATULIN
CAS :Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.Formule :C7H6O4Degré de pureté :99.91%Couleur et forme :Compact Prisms Or Thick Plates From Ether Or Chloroform White CrystallineMasse moléculaire :154.12Ref: TM-T3936
1mg79,00€5mg210,00€10mg349,00€25mgÀ demander50mgÀ demander100mg2.619,00€1mL*10mM (DMSO)120,00€CZC-25146
CAS :CZC-25146, a stable LRRK2 inhibitor, IC50: 4.76 nM (wild-type), 6.87 nM (G2019S).Formule :C22H25FN6O4SDegré de pureté :97.68%Couleur et forme :SolidMasse moléculaire :488.54Topotecan
CAS :Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.Formule :C23H23N3O5Degré de pureté :95.19% - 97.58%Couleur et forme :Light Yellow Needle Crystal Or Crystalline PowderMasse moléculaire :421.45Raloxifene hydrochloride
CAS :Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.Formule :C28H28ClNO4SDegré de pureté :98% - 99.81%Couleur et forme :Light Yellow SolidMasse moléculaire :510.044FERULIC ACID METHYL ESTER
CAS :FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.Formule :C11H12O4Degré de pureté :99.66% - 99.95%Couleur et forme :SolidMasse moléculaire :208.21P62-mediated mitophagy inducer
CAS :P62-mediated mitophagy inducer (PMI) is a regulator of mitophagy .Formule :C14H9IN4O2Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :392.15Ref: TM-T13809
1mg35,00€5mg70,00€10mg96,00€25mg202,00€50mg329,00€100mg527,00€200mg750,00€1mL*10mM (DMSO)81,00€Aloe emodin
CAS :Aloe emodin (Rhabarberone) is an interferon-inducing agent, for JEV (IC50=1 μg/mL) and EV71(IC50=0.33 μg/mL ).Formule :C15H10O5Degré de pureté :97.00%Couleur et forme :Orange SolidMasse moléculaire :270.24Oprozomib
CAS :Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.Formule :C25H32N4O7SDegré de pureté :98% - 99.87%Couleur et forme :SolidMasse moléculaire :532.61Tetrahydrocurcumin
CAS :Tetrahydrocurcumin (HZIV 81-2), a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.Formule :C21H24O6Degré de pureté :99.37%Couleur et forme :Solid PowderMasse moléculaire :372.41GNE-7915
CAS :GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.Formule :C19H21F4N5O3Degré de pureté :98% - ≥95%Couleur et forme :SolidMasse moléculaire :443.4Ref: TM-T1945
5mg47,00€10mg62,00€25mg114,00€50mg187,00€100mg316,00€200mg410,00€500mg680,00€1mL*10mM (DMSO)50,00€Arctigenin
CAS :(-)-Arctigenin ((-)-Arctigenin) is found in burdock.Formule :C21H24O6Degré de pureté :98% - 99.51%Couleur et forme :SolidMasse moléculaire :372.41Obeticholic Acid
CAS :Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.Formule :C26H44O4Degré de pureté :99.88% - 99.97%Couleur et forme :SolidMasse moléculaire :420.63Ref: TM-T1789
5mg48,00€10mg52,00€25mg82,00€50mg99,00€100mg163,00€200mg274,00€500mg505,00€1mL*10mM (DMSO)49,00€Berberine hydrogen sulphate
CAS :Berberine hydrogen sulphate, a plant alkaloid, has broad antimicrobial effects on bacteria, fungi, and protozoa.Formule :C20H19NO8SDegré de pureté :99% - 99.79%Couleur et forme :Yellow Crystals Off-White To Yellow PowderMasse moléculaire :433.43U0126-EtOH
CAS :U0126-EtOH (U0126 Ethanol) is a non-ATP competitive specific inhibitor of MEK1/2 (IC50: 0.07/0.06 μM).Formule :C18H16N6S2·C2H6ODegré de pureté :98.65% - 99.82%Couleur et forme :SolidMasse moléculaire :426.6Dasatinib monohydrate
CAS :Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Formule :C22H28ClN7O3SDegré de pureté :100% - 99.68%Couleur et forme :SolidMasse moléculaire :506.03MK-2206 dihydrochloride
CAS :MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent andFormule :C25H23Cl2N5ODegré de pureté :99.228% - 99.91%Couleur et forme :SolidMasse moléculaire :480.39Ref: TM-T1952
2mg35,00€5mg51,00€10mg70,00€25mg96,00€50mg144,00€100mg216,00€200mg354,00€500mg582,00€1mL*10mM (DMSO)56,00€SG31
SG31 is a potent activator of autophagy, exerting its effects through the AMPK/ULK1-dependent pathway.Formule :C26H37N6O8PCouleur et forme :SolidMasse moléculaire :592.58Notoginsenoside Fc
CAS :1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.Formule :C58H98O26Degré de pureté :99.22% - 99.94%Couleur et forme :SolidMasse moléculaire :1211.38Salbutamol hemisulfate
CAS :Salbutamol hemisulfate (Albuterol Sulfate) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM.Formule :C13H21NO3H2O4SDegré de pureté :99.35%Couleur et forme :White Or Almost White Odourless PowderMasse moléculaire :576.7HDAC-IN-62
HDAC-IN-62 (Compound 5), an HDAC inhibitor, exhibits IC50 values of 0.78, 1.0, and 1.2 μM for HDAC6, HDAC8, and HDAC11, respectively.Formule :C15H14N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.35PD-166866
CAS :PD-166866 is a selective FGFR tyrosine kinase inhibitor.Formule :C20H24N6O3Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :396.44Amsacrine hydrochloride
CAS :Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.Formule :C21H20ClN3O3SDegré de pureté :99.05% - 99.92%Couleur et forme :SolidMasse moléculaire :429.92
