Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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Dynasore
CAS :Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.Formule :C18H14N2O4Degré de pureté :95.85% - 99.22%Couleur et forme :SolidMasse moléculaire :322.31Ref: TM-T1848
5mg49,00€10mg79,00€25mg140,00€50mg259,00€100mg374,00€200mg560,00€500mg883,00€1mL*10mM (DMSO)87,00€Piceatannol
CAS :Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Formule :C14H12O4Degré de pureté :98.66% - 99.57%Couleur et forme :Light Tan To Yellow PowderMasse moléculaire :244.24Isoliquiritigenin
CAS :Isoliquiritigenin (ISL) is a natural flavonoid that inhibits influenza virus and aldose reductase. Isoliquiritigenin has antitumor effect. Cost-effective and quality-assured.Formule :C15H12O4Degré de pureté :97.61% - 99.44%Couleur et forme :PowderMasse moléculaire :256.25GNE0877
CAS :GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).Formule :C14H16F3N7Degré de pureté :98.01% - 99.96%Couleur et forme :SolidMasse moléculaire :339.32Ref: TM-T6031
1mg47,00€2mg60,00€5mg119,00€10mg187,00€25mg376,00€50mg562,00€100mg802,00€500mg1.644,00€1mL*10mM (DMSO)96,00€ZSTK474
CAS :PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potentialFormule :C19H21F2N7O2Degré de pureté :98.29% - 99.76%Couleur et forme :White PowderMasse moléculaire :417.41Skepinone-L
CAS :Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.Formule :C24H21F2NO4Degré de pureté :100% - 99.76%Couleur et forme :SolidMasse moléculaire :425.42Ref: TM-T6130
1mg38,00€2mg49,00€5mg79,00€10mg119,00€25mg208,00€50mg313,00€100mg465,00€1mL*10mM (DMSO)87,00€Rutin
CAS :Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, andFormule :C27H30O16Degré de pureté :95.66% - 97.19%Couleur et forme :SolidMasse moléculaire :610.52Sirtinol
CAS :Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).Formule :C26H22N2O2Degré de pureté :99.52% - 99.96%Couleur et forme :SolidMasse moléculaire :394.47Ref: TM-T6671
2mg43,00€5mg58,00€10mg93,00€25mg178,00€50mg343,00€100mg509,00€500mg1.121,00€1mL*10mM (DMSO)58,00€Cryptotanshinone
CAS :Cryptotanshinone: STAT3 inhibitor, IC50 4.6 μM; blocks STAT3 Tyr705 phosphorylation, minor effect on Ser727, no impact on STAT1/5.Formule :C19H20O3Degré de pureté :97.69% - ≥95%Couleur et forme :Orange Needle CrystalMasse moléculaire :296.36Dihydroartemisinin
CAS :Dihydroartemisinin (Artenimol) is a metabolite of artemisinin.Formule :C15H24O5Degré de pureté :99.41% - 99.72%Couleur et forme :White SolidMasse moléculaire :284.35Paeonol
CAS :Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.Formule :C9H10O3Degré de pureté :98.55% - 99.56%Couleur et forme :White To Beige Crystalline PowderMasse moléculaire :166.17MK-5108
CAS :MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formule :C22H21ClFN3O3SDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :461.94Retro-2
CAS :Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, it protects HeLa cells against Ricin, Stx1 and Stx2.Formule :C19H16N2OSDegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :320.41Parthenolide
CAS :Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.Formule :C15H20O3Degré de pureté :99.10% - 99.46%Couleur et forme :White To Pale Yellow Crystalline PowderMasse moléculaire :248.32NH125
CAS :NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.Formule :C27H45IN2Degré de pureté :98.60%Couleur et forme :SolidMasse moléculaire :524.56Ref: TM-T6605
1mg40,00€2mg52,00€5mg88,00€10mg119,00€25mg264,00€50mg454,00€100mg655,00€1mL*10mM (DMSO)87,00€Cobaltic Protoporphyrin IX chloride
CAS :Cobaltic Protoporphyrin IX chloride (CoPP) is a potent heme oxygenase 1 (HO-1) inducer with antiviral activity that inhibits influenza A virus (IAV) infection by inducing a type I IFN response. mTOR inhibitor-8 is a potent mTOR inhibitor and autophagy inducer with antiviral and antitumor activities.Formule :C34H32ClCoN4O4Degré de pureté :≥95.0%Couleur et forme :SolidMasse moléculaire :655.03Autophagy-IN-7
CAS :Autophagy-IN-7 is an autophagy inhibitor that can be used in tumor research.Formule :C15H11N7Couleur et forme :SolidMasse moléculaire :289.295VX-702
CAS :VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.Formule :C19H12F4N4O2Degré de pureté :100% - 99%Couleur et forme :SolidMasse moléculaire :404.32TBHQ
CAS :TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formule :C10H14O2Degré de pureté :99.17% - 99.53%Couleur et forme :White Solid PowderMasse moléculaire :166.22Ranolazine dihydrochloride
CAS :Ranolazine 2HCl, an antianginal, treats arrhythmia by inhibiting sodium current without changing blood pressure or heart rate.Formule :C24H35Cl2N3O4Degré de pureté :100% - 99.96%Couleur et forme :White Crystalline PowderMasse moléculaire :500.46BRD5631
CAS :BRD5631 is an autophagy enhancer, enhances autophagy through an mTOR-independent pathway.Formule :C30H35N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.62GDC-0349
CAS :GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.Formule :C24H32N6O3Degré de pureté :96.00% - 98.98%Couleur et forme :SolidMasse moléculaire :452.55Ref: TM-T6510
2mg39,00€5mg66,00€10mg107,00€25mg215,00€50mg324,00€100mg462,00€500mgÀ demander1mL*10mM (DMSO)70,00€Afatinib Dimaleate
CAS :Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formule :C32H33ClFN5O11Degré de pureté :100% - 98.11%Couleur et forme :SolidMasse moléculaire :718.08Ref: TM-T1773
1g467,00€5mg40,00€10mg59,00€25mg87,00€50mg107,00€100mg140,00€200mg188,00€500mg313,00€1mL*10mM (DMSO)66,00€mTOR inhibitor-1
CAS :C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.Formule :C16H15BrN2O3Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :363.21kaempferide
CAS :kaempferide (4'-Methylkaempferol) is an O-methylated flavonol present in Kaempferia kaempferi with antiviral activity.Formule :C16H12O6Degré de pureté :98.31% - 99.66%Couleur et forme :SolidMasse moléculaire :300.26SBE13 Hydrochloride
CAS :SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.Formule :C24H28Cl2N2O4Degré de pureté :97.98% - ≥95%Couleur et forme :SolidMasse moléculaire :479.4Clinofibrate
CAS :Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.Formule :C28H36O6Degré de pureté :99.84%Couleur et forme :White Crystalline PowderMasse moléculaire :468.58XCT790
CAS :XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).Formule :C23H13F9N4O3SDegré de pureté :99% - 99.74%Couleur et forme :SolidMasse moléculaire :596.42Pregnenolone
CAS :Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.Formule :C21H32O2Degré de pureté :100% - 99.5%Couleur et forme :SolidMasse moléculaire :316.48Vancomycin hydrochloride
CAS :Vancomycin hydrochloride (Vancomycin HCl) is the hydrochloride salt of vancomycin, a branched tricyclic glycosylated peptide with bactericidal activity againstFormule :C66H76Cl3N9O24Degré de pureté :97.20% - 99.19%Couleur et forme :Off White PowderMasse moléculaire :1485.71Losmapimod
CAS :Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).Formule :C22H26FN3O2Degré de pureté :98.56% - 99.05%Couleur et forme :SolidMasse moléculaire :383.46Ref: TM-T2277
2mg35,00€5mg52,00€10mg78,00€25mg139,00€50mg225,00€100mg406,00€500mg920,00€1mL*10mM (DMSO)55,00€Lanatoside C
CAS :Lanatoside C, a cardiac glycoside, treats heart failure and arrhythmia; taken orally or IV.Formule :C49H76O20Degré de pureté :100% - 99.8%Couleur et forme :SolidMasse moléculaire :985.12Doramapimod
CAS :Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.Formule :C31H37N5O3Degré de pureté :97.73% - 98.80%Couleur et forme :SolidMasse moléculaire :527.66Ref: TM-T6277
1g562,00€5mg37,00€10mg55,00€25mg79,00€50mg92,00€100mg127,00€200mg225,00€500mg379,00€1mL*10mM (DMSO)44,00€QN523
CAS :QN523 has drug-like traits, kills cancer cells in vitro, effective in vivo against pancreatic cancer, works via autophagy.Formule :C14H10N4ODegré de pureté :97.26%Couleur et forme :SolidMasse moléculaire :250.26Ref: TM-T64374
1mg35,00€5mg74,00€10mg105,00€25mg207,00€50mg325,00€100mg469,00€200mg650,00€1mL*10mM (DMSO)71,00€Rosiglitazone
CAS :Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Formule :C18H19N3O3SDegré de pureté :98.61% - 99.87%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :357.43Valproic Acid
CAS :Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.Formule :C8H16O2Degré de pureté :98.91% - 99.49%Couleur et forme :Colourless To Pale Yellow Liquid ViscousMasse moléculaire :144.21Tigecycline
CAS :Tigecycline (GAR-936), a broad-spectrum glycylcycline, disrupts protein synthesis by binding the 30S ribosomal subunit.Formule :C29H39N5O8Degré de pureté :100% - 99.94%Couleur et forme :PowderMasse moléculaire :585.65Ref: TM-T1569
5mg38,00€10mg57,00€25mg79,00€50mg105,00€100mg168,00€200mg248,00€500mg418,00€1mL*10mM (DMSO)59,00€Demethoxycurcumin
CAS :Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.Formule :C20H18O5Degré de pureté :94.54% - 98.1%Couleur et forme :SolidMasse moléculaire :338.35QX77
CAS :QX77 is a chaperone-mediated autophagy (CMA) activator.Formule :C16H13ClN2O2Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :300.74Afatinib
CAS :Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.Formule :C24H25ClFN5O3Degré de pureté :97.56% - 99.9%Couleur et forme :Off-White SolidMasse moléculaire :485.94Ref: TM-T21312
5mg35,00€10mg51,00€25mg86,00€50mg115,00€100mg144,00€200mg177,00€500mg300,00€1mL*10mM (DMSO)52,00€p62-ZZ Ligand-Linker Conjugate 1
CAS :p62-ZZ Ligand-Linker Conjugate 1 is a conjugate of the p62-ZZ domain ligand and linker. This compound is utilized in the synthesis of AUTOTACVinclozolinM2-2204.Formule :C31H42N2O6Couleur et forme :SolidMasse moléculaire :538.68Ciclopirox
CAS :Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.Formule :C12H17NO2Degré de pureté :97.72% - 99.41%Couleur et forme :SolidMasse moléculaire :207.27Vps34-PIK-III
CAS :Vps34-PIK-III (VPS34-IN2), a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and results in the stabilization of autophagy substrates.Formule :C17H17N7Degré de pureté :98.39% - 98.43%Couleur et forme :SolidMasse moléculaire :319.36Ref: TM-T6945
1mg51,00€2mg71,00€5mg116,00€10mg202,00€25mg454,00€50mg663,00€100mg944,00€500mg1.890,00€1mL*10mM (DMSO)116,00€Nitrendipine
CAS :Nitrendipine is a vasodilating calcium channel blocker and antihypertensive that preserves kidney function and promotes sodium excretion.Formule :C18H20N2O6Degré de pureté :99.54% - 99.55%Couleur et forme :SolidMasse moléculaire :360.36Ref: TM-T0119
1g437,00€10mg38,00€25mg55,00€50mg71,00€100mg119,00€200mg175,00€500mg283,00€1mL*10mM (DMSO)55,00€HA15
CAS :HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.Formule :C23H22N4O3S2Degré de pureté :99.77% - 99.86%Couleur et forme :SolidMasse moléculaire :466.58Ref: TM-T6855
1mg40,00€2mg51,00€5mg84,00€10mg96,00€25mg187,00€50mg329,00€100mg567,00€1mL*10mM (DMSO)84,00€Veliparib dihydrochloride
CAS :Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.Formule :C13H18Cl2N4ODegré de pureté :97.09% - 98%Couleur et forme :SolidMasse moléculaire :317.21Danshensu sodium salt
CAS :Danshensu sodium salt (Sodium Danshensu) is sodium salt of danshensu from the widely used Chinese herb Danshen.Formule :C9H9NaO5Degré de pureté :97.04% - 99.52%Couleur et forme :SolidMasse moléculaire :220.16LRRK2 inhibitor 1
CAS :LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.Formule :C20H23N5O4Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :397.43Ref: TM-T11878
1mg74,00€2mg97,00€5mg160,00€10mg264,00€25mg557,00€50mg944,00€100mg1.491,00€1mL*10mM (DMSO)170,00€Chloroquine phosphate
CAS :Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is used as an autophagy inhibitor. Chloroquine also is an inhibitor of TLRs.Formule :C18H26CLN3·2(H3PO4)Degré de pureté :99.64% - ≥95%Couleur et forme :White To Slightly Yellow Crystalline Powder White SolidMasse moléculaire :515.87SRT 1720
CAS :SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.Formule :C25H23N7OSDegré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :469.56Piperlongumine
CAS :Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.Formule :C17H19NO5Degré de pureté :97.03% - 99.89%Couleur et forme :SolidMasse moléculaire :317.34Andrographolide
CAS :Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potentialFormule :C20H30O5Degré de pureté :100% - 99.97%Couleur et forme :PowderMasse moléculaire :350.45L-779450
CAS :L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively.Formule :C20H14ClN3ODegré de pureté :≥95%Couleur et forme :SolidMasse moléculaire :347.86-Thioguanine
CAS :6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formule :C5H5N5SDegré de pureté :100% - 98.75%Couleur et forme :Odorless Or Almost Odorless Pale Yellow Crystalline PowderMasse moléculaire :167.19Quisinostat dihydrochloride
CAS :Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性,高效的 pan-HDAC 抑制剂,具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。Formule :C21H28Cl2N6O2Degré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :467.39Zebularine
CAS :Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.Formule :C9H12N2O5Degré de pureté :100% - 99.84%Couleur et forme :SolidMasse moléculaire :228.2Everolimus
CAS :Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.Formule :C53H83NO14Degré de pureté :97.76% - 99.52%Couleur et forme :Off-White To Light Yellow PowdMasse moléculaire :958.22Ref: TM-T1784
5mg44,00€10mg55,00€25mg82,00€50mg96,00€100mg120,00€200mg177,00€500mg298,00€1mL*10mM (DMSO)55,00€Sodium salicylate
CAS :Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.Formule :C7H5NaO3Degré de pureté :99.36% - 99.77%Couleur et forme :White Solid AmorphousMasse moléculaire :160.11Cilofexor
CAS :Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.Formule :C28H22Cl3N3O5Degré de pureté :99.32% - ≥95%Couleur et forme :SolidMasse moléculaire :586.85Ref: TM-T7436
1mg50,00€2mg73,00€5mg124,00€10mg188,00€25mg380,00€50mg567,00€100mg807,00€500mg1.644,00€1mL*10mM (DMSO)158,00€Rosolutamide
CAS :Rosolutamide (ALZ-003) is a curcumin analog, an Nrf1 and Nrf2 activator.Formule :C28H32O6Degré de pureté :96.54% - 99.36%Couleur et forme :SolidMasse moléculaire :464.55Pantoprazole Sodium Hydrate
CAS :Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagusFormule :C16H14F2N3NaO4SH2ODegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :432.37Di-N-desethyl amiodarone hydrochloride
CAS :Di-N-desethyl Amiodarone hydrochloride, a metabolite of Amiodarone, functions as a potent inhibitor of the respiratory chain [1].Formule :C21H22ClI2NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :625.67Eupatilin
CAS :Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.Formule :C18H16O7Degré de pureté :98.42% - 99%Couleur et forme :SolidMasse moléculaire :344.32UVI 3003
CAS :UVI 3003 blocks retinoid X receptor (RXRα) in Xenopus/human Cos7 cells; IC50: 0.22/0.24 μM.Formule :C28H36O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :436.58Ref: TM-T17209
1mg35,00€2mg52,00€5mg74,00€10mg119,00€25mg243,00€50mg406,00€100mg607,00€1mL*10mM (DMSO)86,00€NDBM
NDBM, a tumor-specific probe that targets Pim-1 kinase, exhibits heightened fluorescence upon binding and induces cytotoxicity, facilitating both cell screeningFormule :C33H35BrN4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :679.56Magnolol
CAS :Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.Formule :C18H18O2Degré de pureté :99.49%Couleur et forme :A Bioactive Compound Found In The Bark Of The Houpu MagnoliaMasse moléculaire :266.33CUR5g
CAS :CUR5g is an autophagy inhibitor that inhibits migration and colony formation in A549 cells.Formule :C22H20N2O2Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :344.41Ref: TM-T73550
1mg92,00€5mg216,00€10mg344,00€25mg692,00€50mg1.103,00€100mg1.644,00€1mL*10mM (DMSO)240,00€ATG7-IN-1
CAS :ATG7-IN-1 is a selective ATG7 inhibitor with an IC50 of 62 nM.Formule :C17H19FN6O5S2Degré de pureté :100% - 100%Couleur et forme :SolidMasse moléculaire :470.5BAR502
CAS :BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).Formule :C25H44O3Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :392.62Resatorvid
CAS :Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.Formule :C15H17ClFNO4SDegré de pureté :100% - 99.9%Couleur et forme :SolidMasse moléculaire :361.82Ref: TM-TQ0181
1mg49,00€2mg70,00€5mg96,00€10mg164,00€25mg306,00€50mg502,00€100mg805,00€1mL*10mM (DMSO)116,00€Polydatin
CAS :Polydatin, a resveratrol glycoside from Polygonum cuspidatum, inhibits platelet aggregation, alters lipid ratios, and modulates cell functions.Formule :C20H22O8Degré de pureté :97.2% - 98.83%Couleur et forme :White Fine PowderMasse moléculaire :390.38LC3-mHTT-IN-AN2
CAS :LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.Formule :C15H10O4Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :254.24Clemastine fumarate
CAS :Clemastine fumarate (Meclastine (fumarate)) is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties.Formule :C25H30ClNO5Degré de pureté :99.52% - 99.8%Couleur et forme :Colorless To Faintly Yellow Crystalline Powder Appearance White Or Almost White Crystalline PowderMasse moléculaire :459.97Rabusertib
CAS :Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.Formule :C18H22BrN5O3Degré de pureté :98.86% - 99.63%Couleur et forme :SolidMasse moléculaire :436.3Dehydrocorydaline chloride
CAS :Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Formule :C22H24ClNO4Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :401.88Ref: TM-T10990
1mg58,00€5mg111,00€10mg160,00€25mg264,00€50mg396,00€100mg563,00€1mL*10mM (DMSO)124,00€ATG16L1 stabilizer-1
ATG16L1 stabilizer-1 (compound A3B) is an FKBP12-independent stabilizer of ATG16L1 that enhances cellular autophagy (Autophagy). Regardless of the presence of FKBP12, it has an inhibitory EC50 value of 12.1 μM for ATG16L1. When used alone, ATG16L1 stabilizer-1 can induce GFP-LC3 puncta formation, with an EC50 value of 12.0 μM.Formule :C45H62N14O5SCouleur et forme :SolidMasse moléculaire :911.13Bafilomycin A1
CAS :Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.Formule :C35H58O9Degré de pureté :95.87% - 99.36%Couleur et forme :SolidMasse moléculaire :622.83Temsirolimus
CAS :Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formule :C56H87NO16Degré de pureté :100% - 99.64%Couleur et forme :White Crystalline PowderMasse moléculaire :1030.29Quisinostat
CAS :Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.Formule :C21H26N6O2Degré de pureté :96.01% - ≥98%Couleur et forme :SolidMasse moléculaire :394.47Ref: TM-T6055
1mg59,00€2mg86,00€5mg124,00€10mg213,00€25mg331,00€50mg427,00€100mg607,00€1mL*10mM (DMSO)139,00€Oroxylin A
CAS :Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.Formule :C16H12O5Degré de pureté :98.72% - 99.55%Couleur et forme :SolidMasse moléculaire :284.26Aceglutamide
CAS :Aceglutamide (N2-Acetylglutamine) is an acetyl derivative of the amino acid L-glutamine, used to improve memory.Formule :C7H12N2O4Degré de pureté :99.56% - 99.77%Couleur et forme :SolidMasse moléculaire :188.18Spironolactone
CAS :Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.Formule :C24H32O4SDegré de pureté :99.87%Couleur et forme :White PowderMasse moléculaire :416.57Nortriptyline hydrochloride
CAS :Nortriptyline HCl, a metabolite of amitriptyline, treats major and atypical depression, dysthymia.Formule :C19H22ClNDegré de pureté :100% - ≥95%Couleur et forme :SolidMasse moléculaire :299.84MTP
CAS :MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation.Formule :C29H23F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :516.51GC7 Sulfate
CAS :GC7 Sulfate blocks DHS, the sole enzyme activating eIF5A2, thus preventing eIF5A2 activation.Formule :C8H22N4O4SDegré de pureté :100% - 99.85%Couleur et forme :SolidMasse moléculaire :270.35Brazilin
CAS :1.Formule :C16H14O5Degré de pureté :98% - 99.83%Couleur et forme :SolidMasse moléculaire :286.28Ref: TM-T6S1784
1mg37,00€5mg74,00€10mg97,00€25mg157,00€50mg224,00€100mg335,00€200mg497,00€1mL*10mM (DMSO)81,00€LYS01
CAS :LYS01 free base is a new lysosomal autophagy inhibitor.Formule :C23H23Cl2N5Degré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :440.37Lumefantrine
CAS :Lumefantrine, an antimalarial, treats malaria with artemether, effective against Plasmodium spp. including in chloroquine-resistant areas.Formule :C30H32Cl3NODegré de pureté :98.36%Couleur et forme :Yellow SolidMasse moléculaire :528.94Aliskiren hemifumarate
CAS :Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity.Formule :C30H53N3O6C4H4O4Degré de pureté :96.18% - 99.21%Couleur et forme :SolidMasse moléculaire :1219.6Zoledronic Acid
CAS :Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐,能抑制破骨细胞的分化和凋亡,具有高效的抗骨质再吸收活性,也有抗癌作用。Formule :C5H10N2O7P2Degré de pureté :98% - 99.93%Couleur et forme :White Crystalline PowderMasse moléculaire :272.09GSK343
CAS :GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity againstFormule :C31H39N7O2Degré de pureté :98% - 99.9%Couleur et forme :SolidMasse moléculaire :541.69Theophylline
CAS :Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and centralFormule :C7H8N4O2Degré de pureté :99.47% - 99.97%Couleur et forme :White Solid PowderMasse moléculaire :180.16Chenodeoxycholic acid
CAS :Chenodeoxycholic acid (CDCA), a bile acid, usually conjugated with either glycine or taurine, acts as a detergent to solubilize fats for intestinal absorption.Formule :C24H40O4Degré de pureté :99.70% - 99.72%Couleur et forme :White - Almost White Solid PowderMasse moléculaire :392.57Monacolin J
CAS :Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.Formule :C19H28O4Degré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :320.42Ref: TM-T12092
1mg79,00€5mg160,00€10mg235,00€25mg398,00€50mg567,00€100mg820,00€1mL*10mM (DMSO)170,00€Purmorphamine
CAS :Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo.Formule :C31H32N6O2Degré de pureté :97.19% - 99.48%Couleur et forme :Light Tan SolidMasse moléculaire :520.62Glyphosate
CAS :Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.Formule :C3H8NO5PDegré de pureté :99.42% - 99.79%Couleur et forme :White Crystals (Darkens) Ph (1% Solution In Water) 2 5 (Ntp 1992)Masse moléculaire :169.07Itraconazole
CAS :Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.Formule :C35H38Cl2N8O4Degré de pureté :98% - 99.90%Couleur et forme :Off-White Crystalline SolidMasse moléculaire :705.63CZC-25146 hydrochloride
CAS :CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.Formule :C22H26ClFN6O4SDegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :525CX546
CAS :CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.Formule :C14H17NO3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :247.29Betulinic acid
CAS :Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.Formule :C30H48O3Degré de pureté :99.12% - 99.7%Couleur et forme :White Crystalline PowderMasse moléculaire :456.7
