Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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Dinoprost
CAS :Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.Formule :C20H34O5Degré de pureté :≥98%Couleur et forme :White To Off-White Crystalline SolidMasse moléculaire :354.48Ref: TM-T15133
5mg51,00€10mg79,00€25mg144,00€50mg216,00€100mg344,00€200mg512,00€1mL*10mM (DMSO)57,00€Pantoprazole sodium
CAS :Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Formule :C16H14F2N3NaO4SDegré de pureté :96.92% - 99.81%Couleur et forme :White To Off-White SolidMasse moléculaire :405.35Elexacaftor
CAS :Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector.Cost-effective and quality-assured.Formule :C26H34F3N7O4SDegré de pureté :98.87% - 99.87%Couleur et forme :SolidMasse moléculaire :597.65Ref: TM-T14935
1mg87,00€2mg137,00€5mg243,00€10mg393,00€25mg772,00€50mg1.074,00€100mg1.444,00€1mL*10mM (DMSO)320,00€TFEB activator 1
CAS :TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer'sFormule :C19H18O3Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :294.34AZD7624
CAS :AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Formule :C27H30FN5O3Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :491.56Ref: TM-T14381
1mg73,00€5mg160,00€10mg250,00€25mg507,00€50mg737,00€100mg1.026,00€1mL*10mM (DMSO)170,00€SR10067
CAS :SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbβ(IC50 = 160 nM) and Rev-Erbα(IC50 = 170 nM) with anxiolytic activity.Formule :C31H31NO3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :465.58Ref: TM-T12998
1mg58,00€5mg134,00€10mg207,00€25mg353,00€50mg510,00€100mg658,00€200mg905,00€1mL*10mM (DMSO)144,00€Oxidopamine hydrobromide
CAS :Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Formule :C8H12BrNO3Degré de pureté :98.1% - 99.88%Couleur et forme :Beige To Brown Fine Crystalline PowderMasse moléculaire :250.09Naringin
CAS :Naringin: flavanone glycoside with blood lipid-reducing, antioxidant, anticancer properties, inhibits cytochrome P450.Formule :C27H32O14Degré de pureté :99.23%Couleur et forme :Beige Creamish Powder Solid Solid Particulate/PowderMasse moléculaire :580.53FMK 9a
CAS :FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.Formule :C23H21FN2O3Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :392.42Ref: TM-T15303
1mg139,00€5mg329,00€10mg494,00€25mg800,00€50mg1.103,00€100mg1.491,00€500mg2.973,00€1mL*10mM (DMSO)284,00€GPP78
CAS :GPP78: Strong Nampt inhibitor, IC50 3.0 nM, depletes NAD. Kills SH-SY5Y cells, IC50 3.8 nM via autophagy. Anti-cancer and anti-inflammatory.Formule :C27H29N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.55MRT67307
CAS :Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.Formule :C26H36N6O2Degré de pureté :99.25% - 99.79%Couleur et forme :SolidMasse moléculaire :464.6Nidufexor
CAS :Nidufexor is an agonist for the farnesoid X receptor (FXR).Formule :C27H22ClN3O4Degré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :487.93Daphnetin
CAS :Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formule :C9H6O4Degré de pureté :97.47% - 99.8%Couleur et forme :SolidMasse moléculaire :178.14Paroxetine hydrochloride
CAS :Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.Formule :C19H21ClFNO3Degré de pureté :98% - 99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :365.826Ruxolitinib phosphate
CAS :Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formule :C17H21N6O4PDegré de pureté :100% - 99.91%Couleur et forme :SolidMasse moléculaire :404.36Ref: TM-T3043
1g615,00€5mg52,00€10mg65,00€25mg82,00€50mg97,00€100mg145,00€200mg227,00€500mg418,00€1mL*10mM (DMSO)59,00€Doxorubicin hydrochloride
CAS :Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Formule :C27H29NO11·HClDegré de pureté :98% - 99.36%Couleur et forme :Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Masse moléculaire :579.99Calmidazolium chloride
CAS :Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.Formule :C31H23Cl7N2ODegré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :687.7Ref: TM-T10667
5mg63,00€10mg87,00€25mg145,00€50mg215,00€100mg320,00€200mg467,00€1mL*10mM (DMSO)95,00€PF-4708671
CAS :PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671 is potent for S6K1(Ki50=20 nM, IC50=160 nM).Formule :C19H21F3N6Degré de pureté :99.48% - 99.67%Couleur et forme :SolidMasse moléculaire :390.41Procainamide hydrochloride
CAS :Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analogFormule :C13H21N3O·HClDegré de pureté :99.83% - 99.97%Couleur et forme :White To Slightly Yellow PowderMasse moléculaire :271.79Pinocembrin
CAS :Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.Formule :C15H12O4Degré de pureté :100% - 99.61%Couleur et forme :SolidMasse moléculaire :256.25Actein
CAS :Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.Formule :C37H56O11Degré de pureté :≥98%Couleur et forme :Brown PowderMasse moléculaire :676.83Rutin hydrate
CAS :Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.Formule :C27H32O17Degré de pureté :97.23%Couleur et forme :SolidMasse moléculaire :628.53Simvastatin
CAS :Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.Formule :C25H38O5Degré de pureté :98.54% - 99.13%Couleur et forme :SolidMasse moléculaire :418.57Ref: TM-T0687
10mg43,00€25mg58,00€50mg69,00€100mg106,00€200mg140,00€500mg270,00€1mL*10mM (DMSO)47,00€GW 501516
CAS :GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Formule :C21H18F3NO3S2Degré de pureté :98.91% - 99.64%Couleur et forme :White SolidMasse moléculaire :453.5Atorvastatin
CAS :Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.Formule :C33H35FN2O5Degré de pureté :99.37% - 99.69%Couleur et forme :SolidMasse moléculaire :558.64Biochanin A
CAS :Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.Formule :C16H12O5Degré de pureté :97.1% - 98.97%Couleur et forme :SolidMasse moléculaire :284.26BAY 11-7082
CAS :BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).Formule :C10H9NO2SDegré de pureté :97.91% - 99.92%Couleur et forme :SolidMasse moléculaire :207.25Ref: TM-T1902
5mg50,00€10mg57,00€25mg96,00€50mg170,00€100mg265,00€200mg399,00€500mg662,00€1mL*10mM (DMSO)52,00€CCG-1423
CAS :CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.Formule :C18H13ClF6N2O3Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :454.75CXM102
CXM102 is an activator of autophagy. This compound induces autophagy in aged BMSCs, rejuvenating them and promoting their preferential differentiation into osteoblasts. CXM102 enhances the nuclear translocation of transcription factor EB (TFEB) and the formation of osteoblasts. In middle-aged male mice, it stimulates bone anabolic metabolism, reduces marrow adipocytes, delays bone loss, lowers serum inflammation levels, reduces organ fibrosis, and extends lifespan.Formule :C28H27NO3Couleur et forme :SolidMasse moléculaire :425.52Crizotinib
CAS :Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.Formule :C21H22Cl2FN5ODegré de pureté :99% - 99.87%Couleur et forme :SolidMasse moléculaire :450.34GW 4064
CAS :GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).Formule :C28H22Cl3NO4Degré de pureté :97.47% - 99.94%Couleur et forme :SolidMasse moléculaire :542.84Ref: TM-T2233
5mg50,00€10mg84,00€25mg139,00€50mg235,00€100mg424,00€200mg640,00€500mg1.008,00€1mL*10mM (DMSO)63,00€Ralimetinib dimesylate
CAS :Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.Formule :C24H29FN6·2CH4O3SDegré de pureté :98% - 99.38%Couleur et forme :SolidMasse moléculaire :612.74Cytarabine
CAS :Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).Formule :C9H13N3O5Degré de pureté :99.83% - 99.93%Couleur et forme :Fine Off-White Crystalline PowderMasse moléculaire :243.22Pravastatin sodium
CAS :Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.Formule :C23H35NaO7Degré de pureté :97.14%Couleur et forme :White Crystalline PowderMasse moléculaire :446.52Adenosine
CAS :Adenosine (D-Adenosine) is a ribonucleoside. Adenosine has vasodilatory, antiarrhythmic and analgesic effects. Cost-effective and quality-assured.Formule :C10H13N5O4Degré de pureté :98.76% - 99.86%Couleur et forme :Needles (From Water +3/2) Physical Description White To Off-White Crystalline Powder (Ntp 1992)Masse moléculaire :267.24Glucosamine sulfate
CAS :Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.Formule :C6H13NO5·H2SO4Degré de pureté :99.64%Couleur et forme :White CrystalMasse moléculaire :277.25ML327
CAS :ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).Formule :C19H18N4O4Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :366.37Sorafenib tosylate
CAS :Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).Formule :C21H16ClF3N4O3·C7H8O3SDegré de pureté :99.2% - 99.94%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :637.03Nordihydroguaiaretic acid
CAS :Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Formule :C18H22O4Degré de pureté :97.82% - 99.91%Couleur et forme :SolidMasse moléculaire :302.36GSK2606414
CAS :GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase(PERK)inhibitor.Cost-effective and quality-assured.Formule :C24H20F3N5ODegré de pureté :100% - 98.63%Couleur et forme :SolidMasse moléculaire :451.44Erythromycin ethylsuccinate
CAS :Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus.Formule :C43H75NO16Degré de pureté :77% - 98%Couleur et forme :White Or Slightly Yellow Crystalline Powder White To Yellowish Crystalline SolidMasse moléculaire :862.05GSK3-IN-3
CAS :GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy.Formule :C24H35N3O4Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :429.55Mocetinostat
CAS :Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.Formule :C23H20N6ODegré de pureté :99% - 99.21%Couleur et forme :SolidMasse moléculaire :396.44Hemin
CAS :Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.Formule :C34H32ClFeN4O4Degré de pureté :98.29% - 99.59%Couleur et forme :Dark Purple Crystalline PowderMasse moléculaire :651.94LX2343
CAS :LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.Formule :C22H19ClN2O6SDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :474.91Ref: TM-T4398
2mg37,00€5mg52,00€10mg84,00€25mg137,00€50mg229,00€100mg340,00€200mg472,00€1mL*10mM (DMSO)58,00€Perphenazine
CAS :Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.Formule :C21H26ClN3OSDegré de pureté :99.3% - 99.72%Couleur et forme :SolidMasse moléculaire :403.97Naproxen sodium
CAS :Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.Formule :C14H13NaO3Degré de pureté :99.68% - 99.79%Couleur et forme :White PowderMasse moléculaire :252.24Rapamycin
CAS :Rapamycin, a macrolide from Streptomyces hygroscopicus, inhibits mTOR (IC50: 0.1 nM) and promotes autophagy with immunosuppressive effects.Formule :C51H79NO13Degré de pureté :97.08% - 99.03%Couleur et forme :Yellow SolidMasse moléculaire :914.17Ref: TM-T1537
1g283,00€10mg35,00€25mg48,00€50mg52,00€100mg69,00€200mg106,00€500mg188,00€1mL*10mM (DMSO)50,00€Nimodipine
CAS :Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.Formule :C21H26N2O7Degré de pureté :99.64% - 99.79%Couleur et forme :SolidMasse moléculaire :418.44Thiamet G
CAS :Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37, 000-fold selectivity over human lysosomal -hexosaminidase.Formule :C9H16N2O4SDegré de pureté :99.74% - 99.76%Couleur et forme :SolidMasse moléculaire :248.3Ref: TM-T6056
2mg44,00€5mg63,00€10mg93,00€25mg188,00€50mg343,00€100mg510,00€500mg1.130,00€1mL*10mM (DMSO)63,00€Fluoxetine
CAS :Fluoxetine (LY-110140), a specific serotonin inhibitor, serves as an antidepressant with fewer side-effects.Formule :C17H18F3NODegré de pureté :99.07% - 99.28%Couleur et forme :SolidMasse moléculaire :309.33Rottlerin
CAS :Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.Formule :C30H28O8Degré de pureté :97.41% - 99.44%Couleur et forme :Orange To Brown PowderMasse moléculaire :516.54Daurisoline
CAS :Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.Formule :C37H42N2O6Degré de pureté :98% - 99.92%Couleur et forme :Light Yellow PowderMasse moléculaire :610.74SU11274
CAS :SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.Formule :C28H30ClN5O4SDegré de pureté :98.62% - 99.44%Couleur et forme :Orange PowderMasse moléculaire :568.09Ref: TM-T6154
1mg47,00€2mg59,00€5mg97,00€10mg150,00€25mg283,00€50mg465,00€100mg688,00€1mL*10mM (DMSO)150,00€EACC
CAS :EACC inhibits Stx17, blocking autophagosome-lysosome fusion, and is a reversible autophagy inhibitor.Formule :C13H11N3O6S2Degré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :369.37AZ PFKFB3 26
CAS :AZ PFKFB3 26 is an effective and selective PFKFB3 inhibitor with an IC50 of 23 nM. The IC50s for PFKFB1 and PFKFB2 are 2.06 and 0.384 μM, respectively.Formule :C24H26N4O2Degré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :402.49GSK4112
CAS :GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.Formule :C18H21ClN2O4SDegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :396.89Silmitasertib sodium salt
CAS :Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).Formule :C19H11ClN3NaO2Degré de pureté :99.49% - 99.62%Couleur et forme :SolidMasse moléculaire :371.75Ataluren
CAS :Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.Formule :C15H9FN2O3Degré de pureté :99.16% - 99.84%Couleur et forme :SolidMasse moléculaire :284.24Ref: TM-T1805
5mg38,00€10mg57,00€25mg93,00€50mg124,00€100mg188,00€200mg225,00€500mg379,00€1mL*10mM (DMSO)48,00€Streptozocin
CAS :Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation.Formule :C8H15N3O7Degré de pureté :100% - 99.56%Couleur et forme :Pale Yellow Crystalline PowderMasse moléculaire :265.22Bergenin
CAS :Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.Formule :C14H16O9Degré de pureté :99.55% - 99.60%Couleur et forme :The Loose White Needle Crystal Powder Or CrystallineMasse moléculaire :328.27NL-1
CAS :NL-1 is a mitoNEET inhibitor with antileukemic effect.Formule :C18H25NO3SDegré de pureté :98.64%Couleur et forme :SolidMasse moléculaire :335.46PH-797804
CAS :PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.Formule :C22H19BrF2N2O3Degré de pureté :97.79% - 97.90%Couleur et forme :SolidMasse moléculaire :477.3Ref: TM-T1974
1mg46,00€5mg94,00€10mg144,00€25mg255,00€50mg406,00€100mg628,00€500mg1.320,00€1mL*10mM (DMSO)97,00€Purvalanol A
CAS :Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.Formule :C19H25ClN6ODegré de pureté :98.13% - 98.91%Couleur et forme :PowderMasse moléculaire :388.89Quinacrine dihydrochloride
CAS :Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplasticFormule :C23H30CLN3O·2HClDegré de pureté :98.24% - 99.72%Couleur et forme :Yellow Crystals Or PowderMasse moléculaire :472.88Avermectin B1
CAS :Avermectin B1 is served as anthelmintic and insecticide.Formule :C48H72O14Degré de pureté :mixture - mixtureCouleur et forme :White PowderMasse moléculaire :873.09ICCB-19 hydrochloride
CAS :ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.Formule :C12H22ClN3OSDegré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :291.84Ref: TM-T8931L
5mg35,00€10mg52,00€25mg96,00€50mg145,00€100mg210,00€200mg313,00€500mg495,00€1mL*10mM (DMSO)35,00€Sertindole
CAS :Sertindole, atypical antipsychotic, targets D2, 5-HT1D, 5-HT2A, 5-HT2C receptors (Kds: 2.7, 20, 0.14, 6 nM).Formule :C24H26ClFN4ODegré de pureté :99.74%Couleur et forme :Off-White To Pale Yellow SolidMasse moléculaire :440.94Ruxolitinib
CAS :Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.Formule :C17H18N6Degré de pureté :100% - 99.99%Couleur et forme :SolidMasse moléculaire :306.36Ref: TM-T1829
5mg58,00€10mg74,00€25mg92,00€50mg116,00€100mg155,00€200mg245,00€500mg414,00€1mL*10mM (DMSO)65,00€Acacetin
CAS :Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidantFormule :C16H12O5Degré de pureté :96.26% - ≥98%Couleur et forme :Pale-Yellow NeedlesMasse moléculaire :284.26WYE-354
CAS :WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).Formule :C24H29N7O5Degré de pureté :97.86% - 99.61%Couleur et forme :SolidMasse moléculaire :495.53N6-Isopentenyladenosine
CAS :N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity.Formule :C15H21N5O4Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :335.36Chloramphenicol
CAS :Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.Formule :C11H12Cl2N2O5Degré de pureté :99.6% - 99.84%Couleur et forme :Needles Or Elongated Plates From Water Or Ethylene Dichloride SolidMasse moléculaire :323.13EB-42486
CAS :EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.Formule :C22H22N8ODegré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :414.46Ref: TM-T39972
1mg70,00€2mg93,00€5mg156,00€10mg226,00€25mg409,00€50mg610,00€100mg867,00€200mg1.159,00€1mL*10mM (DMSO)170,00€Sanguinarine
CAS :Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.Formule :C20H14NO4Degré de pureté :99.04% - 99.18%Couleur et forme :SolidMasse moléculaire :332.33Regorafenib Hydrochloride
CAS :Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.Formule :C21H16Cl2F4N4O3Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :519.289-ING-41
CAS :9-ING-41 is a glycogen synthase kinase-3 inhibitor.Formule :C22H13FN2O5Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :404.35Ref: TM-T14066
1mg49,00€2mg70,00€5mg99,00€10mg163,00€25mg325,00€50mg472,00€100mg705,00€1mL*10mM (DMSO)116,00€N-Benzyllinolenamide
CAS :N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).Formule :C25H37NODegré de pureté :98.00% - 99.92%Couleur et forme :SolidMasse moléculaire :367.57Ref: TM-TN1965
1mg88,00€5mg187,00€10mg281,00€25mg475,00€50mg692,00€100mg935,00€200mg1.264,00€1mL*10mM (DMSO)188,00€Omipalisib
CAS :Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.Formule :C25H17F2N5O3SDegré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :505.5Melatonin
CAS :Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.Formule :C13H16N2O2Degré de pureté :98% - 99.79%Couleur et forme :Pale Yellow Leaflets From Benzene SolidMasse moléculaire :232.28Triclosan
CAS :Triclosan (Irgasan) is an antibacterial and antifungal agent.Formule :C12H7Cl3O2Degré de pureté :99.63%Couleur et forme :White Solid CrystallineMasse moléculaire :289.54Galangin
CAS :Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity.Formule :C15H10O5Degré de pureté :98.24% - 99.93%Couleur et forme :Yellowish Needle-Like CrystalMasse moléculaire :270.24Briciclib
CAS :Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.Formule :C19H23O10PSDegré de pureté :98% - 99.84%Couleur et forme :SolidMasse moléculaire :474.42Ref: TM-T3207
1mg47,00€2mg57,00€5mg88,00€10mg126,00€25mg250,00€50mg376,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)87,00€PFE-360
CAS :PFE-360 (PF-06685360) is a potent and selective inhibitor of LRRK2 kinase (IC50: 2.3 nM in vivo).Formule :C16H16N6ODegré de pureté :98.14% - 99.73%Couleur et forme :SolidMasse moléculaire :308.34Sorafenib
CAS :Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57Formule :C21H16ClF3N4O3Degré de pureté :98% - 99.89%Couleur et forme :SolidMasse moléculaire :464.82Dasatinib
CAS :Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Formule :C22H26ClN7O2SDegré de pureté :99.59% - 99.86%Couleur et forme :Pale-Yellow SolidMasse moléculaire :488.01Bacilotetrin C analogue
Bacilotetrin C analogue is a variant of Bacilotetrin C. It exhibits cytotoxicity against the triple-negative breast cancer cell line MDA-MB-231, with an IC50 of 0.48 μM. This compound induces autophagy (autophagy) in tumor cells and possesses antitumor activity.Formule :C44H76N6O10Couleur et forme :SolidMasse moléculaire :849.11Indophagolin
CAS :Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.Formule :C19H15BrClF3N2O3SDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :523.75Ref: TM-T8946
1mg58,00€5mg111,00€10mg170,00€25mg284,00€50mg393,00€100mg552,00€200mg748,00€1mL*10mM (DMSO)129,00€Hesperetin
CAS :Hesperetin belongs to the flavanone class of flavonoids.Formule :C16H14O6Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :302.28SN-38
CAS :SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM).Formule :C22H20N2O5Degré de pureté :98% - 99.97%Couleur et forme :Light-Yellow SolidMasse moléculaire :392.44,4'-Dimethoxychalcone
CAS :4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.Formule :C17H16O3Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :268.31Linagliptin
CAS :Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.Formule :C25H28N8O2Degré de pureté :99.15% - 99.95%Couleur et forme :SolidMasse moléculaire :472.54FTO-IN-10
FTO-IN-10 (compound 7), a potent inhibitor of the human demethylase FTO (fat mass and obesity-associated protein), exhibits an IC50 of 4.5 μM.Degré de pureté :98%Couleur et forme :Odour SolidBIX 02565
CAS :BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).Formule :C26H30N6O2Degré de pureté :97.44% - 99.61%Couleur et forme :SolidMasse moléculaire :458.56Felodipine
CAS :Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.Formule :C18H19Cl2NO4Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :384.25Ref: TM-T0145
5mg51,00€10mg82,00€25mg124,00€50mg180,00€100mg264,00€200mg398,00€500mg647,00€1mL*10mM (DMSO)90,00€(+)-JQ-1
CAS :(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.Formule :C23H25ClN4O2SDegré de pureté :97.57% - ≥95%Couleur et forme :SolidMasse moléculaire :456.99Ref: TM-T2110
1mg35,00€2mg44,00€5mg60,00€10mg79,00€25mg96,00€50mg144,00€100mg188,00€200mg283,00€500mg512,00€1mL*10mM (DMSO)66,00€ISRIB (trans-isomer)
CAS :ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.Formule :C22H24Cl2N2O4Degré de pureté :97.86% - 99.27%Couleur et forme :SolidMasse moléculaire :451.34Glibenclamide
CAS :Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formule :C23H28ClN3O5SDegré de pureté :99.05% - 99.75%Couleur et forme :SolidMasse moléculaire :494Binimetinib
CAS :Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity. Cost-effective and quality-assured.Formule :C17H15BrF2N4O3Degré de pureté :100% - 99%Couleur et forme :SolidMasse moléculaire :441.23Hydroxychloroquine sulfate
CAS :Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase.Formule :C18H26ClN3O·H2SO4Degré de pureté :98.92% - 99.88%Couleur et forme :Odorless SolidMasse moléculaire :433.95
