Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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AZD1208
CAS :AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.Formule :C21H21N3O2SDegré de pureté :97.24% - 99.83%Couleur et forme :SolidMasse moléculaire :379.48Ref: TM-T2300
2mg38,00€5mg51,00€10mg74,00€25mg118,00€50mg213,00€100mg378,00€200mg495,00€500mg792,00€1mL*10mM (DMSO)57,00€Sildenafil citrate
CAS :Sildenafil citrate, a PDE5 inhibitor for erectile dysfunction and occasionally pulmonary hypertension.Formule :C28H38N6O11SDegré de pureté :99.59% - 99.97%Couleur et forme :White SolidMasse moléculaire :666.7Piperine
CAS :Piperine (Bioperine) , a alkaloid, has been used in trials studying the treatment of multiple myeloma and deglutition disorders.Formule :C17H19NO3Degré de pureté :100% - 97.79%Couleur et forme :SolidMasse moléculaire :285.34Cyclovirobuxine D
CAS :Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.Formule :C26H46N2ODegré de pureté :97.78% - 98%Couleur et forme :SolidMasse moléculaire :402.66Embelin
CAS :Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formule :C17H26O4Degré de pureté :97.07% - 99.88%Couleur et forme :SolidMasse moléculaire :294.39PTC-209 hydrobromide
CAS :PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results inFormule :C17H13Br2N5OS·HBrDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :576.1TWS119
CAS :TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiationFormule :C18H14N4O2Degré de pureté :98.02% - 99.13%Couleur et forme :SolidMasse moléculaire :318.33Skatole
CAS :Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Formule :C9H9NDegré de pureté :99.74%Couleur et forme :Leaves From Petroleum Ether; White-Brown Scales SolidMasse moléculaire :131.17Ginsenoside F2
CAS :Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.Formule :C42H72O13Degré de pureté :99.04% - 99.3%Couleur et forme :SolidMasse moléculaire :785.01Ref: TM-T3916
1mg35,00€5mg69,00€10mg88,00€25mg144,00€50mg205,00€100mg303,00€500mg735,00€1mL*10mM (DMSO)97,00€CD437
CAS :CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.Formule :C27H26O3Degré de pureté :98.79% - 99.63%Couleur et forme :SolidMasse moléculaire :398.49Triptonide
CAS :Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.Formule :C20H22O6Degré de pureté :99.11% - 99.64%Couleur et forme :White Crystalline PowderMasse moléculaire :358.39Ref: TM-T5S1058
1mg56,00€5mg114,00€10mg166,00€25mg283,00€50mg454,00€100mg660,00€200mg917,00€1mL*10mM (DMSO)140,00€Hoechst 33342 trihydrochloride
CAS :Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.Formule :C27H31Cl3N6ODegré de pureté :98.73% - ≥98%Couleur et forme :SolidMasse moléculaire :561.93TA-02
CAS :TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.Formule :C20H13F2N3Degré de pureté :99.35% - 99.79%Couleur et forme :SolidMasse moléculaire :333.33Ref: TM-T4646
5mg39,00€10mg58,00€25mg104,00€50mg160,00€100mg244,00€500mgÀ demander1mL*10mM (DMSO)43,00€Rosuvastatin
CAS :Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.Formule :C22H28FN3O6SDegré de pureté :95.24% - 99.8%Couleur et forme :SolidMasse moléculaire :481.54Imiquimod
CAS :Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist.Formule :C14H16N4Degré de pureté :100% - 99.62%Couleur et forme :White To Off White Crystalline PowderMasse moléculaire :240.3SAFit2
CAS :SAFit2 is a highly potent and selective inhibitor of fk506 binding protein 51 (FKBP51).Cost-effective and quality-assuredFormule :C46H62N2O10Degré de pureté :98.24% - 99.96%Couleur et forme :SolidMasse moléculaire :802.99Ref: TM-T16836
1mg92,00€5mg197,00€10mg296,00€25mg504,00€50mg717,00€100mg938,00€200mg1.320,00€1mL*10mM (DMSO)261,00€Azithromycin
CAS :Azithromycin (CP 62993) is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.Formule :C38H72N2O12Degré de pureté :99.88% - 99.9%Couleur et forme :White To Off-White Solid CrystallineMasse moléculaire :748.98Wogonin
CAS :Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.Formule :C16H12O5Degré de pureté :98% - 99.8%Couleur et forme :Yellow CrystalMasse moléculaire :284.26Oxybenzone
CAS :Oxybenzone (Eusolex 4360) is an organic compound used in sunscreens. It is a derivative of benzophenone.Formule :C14H12O3Degré de pureté :99.70%Couleur et forme :Colorless Crystals Physical Description White To Off-White Or Light Yellow Powder (Ntp 1992)Masse moléculaire :228.24Glucosamine
CAS :Glucosamine (Chitosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids.Formule :C6H13NO5Degré de pureté :99.80% - 99.80%Couleur et forme :CoaMasse moléculaire :179.17Imatinib Mesylate
CAS :Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,Formule :C29H31N7O·CH4SO3Degré de pureté :100% - 99.97%Couleur et forme :White Crystalline PowderMasse moléculaire :589.71Polyphyllin G
CAS :Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas.Formule :C51H84O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1049.21PFK-158
CAS :PFK-158 is an effective and specific inhibitor PFKFB3.Formule :C18H11F3N2ODegré de pureté :95.49% - 98.58%Couleur et forme :SolidMasse moléculaire :328.29Ref: TM-T3105
1mg35,00€2mg48,00€5mg70,00€10mg96,00€25mg173,00€50mg273,00€100mg432,00€1mL*10mM (DMSO)77,00€Adezmapimod
CAS :Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.Formule :C21H16FN3OSDegré de pureté :99.42% - 99.87%Couleur et forme :White SolidMasse moléculaire :377.43UNC1999
CAS :UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).Formule :C33H43N7O2Degré de pureté :100% - 99.49%Couleur et forme :SolidMasse moléculaire :569.74Ref: TM-T3057
1mg37,00€2mg52,00€5mg71,00€10mg97,00€25mg177,00€50mg286,00€100mg515,00€500mg1.130,00€1mL*10mM (DMSO)89,00€D-glutamine
CAS :D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Formule :C5H10N2O3Degré de pureté :99.99%Couleur et forme :White Or Off-White PowderMasse moléculaire :146.14MLi-2
CAS :MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.Formule :C21H25N5O2Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :379.46Ref: TM-T16115
1mg66,00€2mg96,00€5mg133,00€10mg197,00€25mg435,00€50mg658,00€100mg937,00€1mL*10mM (DMSO)142,00€Lycorine hydrochloride
CAS :Lycorine hydrochloride (Narcissine hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.Formule :C16H18ClNO4Degré de pureté :99.45% - 99.49%Couleur et forme :Fine Crystal PowderMasse moléculaire :323.77Regorafenib
CAS :Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFormule :C21H15ClF4N4O3Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :482.82Ref: TM-T1792
5mg35,00€10mg51,00€25mg80,00€50mg96,00€100mg144,00€200mg185,00€500mg309,00€1mL*10mM (DMSO)57,00€Erlotinib
CAS :Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formule :C22H23N3O4Degré de pureté :98.19% - 99.98%Couleur et forme :White To Off-White PowderMasse moléculaire :393.44Butein
CAS :Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formule :C15H12O5Degré de pureté :100% - 99.85%Couleur et forme :SolidMasse moléculaire :272.25Ref: TM-T6427
1mg43,00€2mg56,00€5mg88,00€10mg106,00€25mg213,00€50mg344,00€100mg550,00€1mL*10mM (DMSO)87,00€Genistein
CAS :Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formule :C15H10O5Degré de pureté :98.22% - 99.69%Couleur et forme :Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMasse moléculaire :270.24KU-55933
CAS :KU-55933 (ATM Kinase Inhibitor) is an ATM inhibitor that is selective and ATP-competitive. KU-55933 has antitumor effects. Cost-effective and quality-assured.Formule :C21H17NO3S2Degré de pureté :100% - 99.80%Couleur et forme :SolidMasse moléculaire :395.49Arglabin
CAS :Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.Formule :C15H18O3Degré de pureté :99.62% - 99.62%Couleur et forme :SolidMasse moléculaire :246.3Ref: TM-TQ0165
1mg104,00€5mg240,00€10mg360,00€25mg520,00€50mg692,00€100mg1.035,00€1mL*10mM (DMSO)310,00€Lys05
CAS :Lys05, a potent autophagy inhibitor, outperforms HCQ in cancer treatment, showing promise for drug development.Formule :C23H26Cl5N5Degré de pureté :99.13% - 99.45%Couleur et forme :SolidMasse moléculaire :549.75Salubrinal
CAS :Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).Formule :C21H17Cl3N4OSDegré de pureté :100% - 98.25%Couleur et forme :SolidMasse moléculaire :479.81Ref: TM-T3045
2mg42,00€5mg62,00€10mg93,00€25mg163,00€50mg274,00€100mg465,00€500mg1.035,00€1mL*10mM (DMSO)67,00€yangonin
CAS :Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.Formule :C15H14O4Degré de pureté :98.82% - 99.55%Couleur et forme :Pale Yellow PowderMasse moléculaire :258.27Ref: TM-T3S0738
1mg70,00€5mg135,00€10mg207,00€25mg349,00€50mg515,00€100mg735,00€1mL*10mM (DMSO)177,00€Rupatadine Fumarate
CAS :Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM.Formule :C26H26ClN3·C4H4O4Degré de pureté :99.86%Couleur et forme :White Or Almost-White PowderMasse moléculaire :532.03BRD4 degrader-5
BRD4 degrader-5 (Compound 23) is a protein degrader utilizing a hydrophobic tag (HyTag) that targets BRD4 for degradation through endoplasmic reticulum stress and the autophagy-lysosome pathway (DC50 = 24.7 μM). It also inhibits the proliferation of 4T1 cancer cells, with an IC50 of 20.6 μM.Formule :C35H42ClN7O2SCouleur et forme :SolidMasse moléculaire :660.27Sulfasalazine
CAS :Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Formule :C18H14N4O5SDegré de pureté :98.00% - 99.28%Couleur et forme :Minute Brownish-Yellow CrystalsMasse moléculaire :398.39Fasudil
CAS :Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Formule :C14H17N3O2SDegré de pureté :99.79% - 99.84%Couleur et forme :SolidMasse moléculaire :291.37Pirarubicin
CAS :Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.Formule :C32H37NO12Degré de pureté :97.61% - 98.27%Couleur et forme :Red Crystalline PowderMasse moléculaire :627.64Ponatinib
CAS :Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormule :C29H27F3N6ODegré de pureté :98% - 99.60%Couleur et forme :SolidMasse moléculaire :532.56PR-619
CAS :PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.Formule :C7H5N5S2Degré de pureté :100% - 99.10%Couleur et forme :SolidMasse moléculaire :223.28Cabergoline
CAS :Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.Formule :C26H37N5O2Degré de pureté :99.86%Couleur et forme :White Crystalline SolidMasse moléculaire :451.6Pemetrexed disodium hemipenta hydrate
CAS :Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.Formule :C20H21N5O6·2NaH2ODegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :518.43Omeprazole
CAS :Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Formule :C17H19N3O3SDegré de pureté :98.43% - 98.48%Couleur et forme :White SolidMasse moléculaire :345.42Vistusertib
CAS :Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.Formule :C25H30N6O3Degré de pureté :97.08% - 99.06%Couleur et forme :SolidMasse moléculaire :462.54Ref: TM-T1961
1mg37,00€5mg74,00€10mg117,00€25mg173,00€50mg236,00€100mg378,00€200mg558,00€1mL*10mM (DMSO)84,00€Juglanin
CAS :Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.Formule :C20H18O10Degré de pureté :98.8% - 99.33%Couleur et forme :SolidMasse moléculaire :418.35Citalopram hydrobromide
CAS :Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, therebyFormule :C20H22BrFN2ODegré de pureté :99.81%Couleur et forme :White Crystalline PowderMasse moléculaire :405.304Linifanib
CAS :Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormule :C21H18FN5ODegré de pureté :98% - 98.24%Couleur et forme :SolidMasse moléculaire :375.4Ref: TM-T2514
5mg50,00€10mg85,00€25mg126,00€50mg188,00€100mg274,00€200mg505,00€500mg815,00€1mL*10mM (DMSO)52,00€Metformin hydrochloride
CAS :Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.Formule :C4H12ClN5Degré de pureté :97.53% - 99.00%Couleur et forme :White Or Almost White Crystals Solid CrystallineMasse moléculaire :165.63HG-10-102-01
CAS :HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).Formule :C17H20ClN5O3Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :377.83Ref: TM-T7196
2mg38,00€5mg58,00€10mg94,00€25mg170,00€50mg264,00€100mg380,00€200mg540,00€1mL*10mM (DMSO)65,00€Quercitrin
CAS :Quercitrin (3-rhamnosyl quercetin) is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities.Formule :C21H20O11Degré de pureté :98.4% - 98.89%Couleur et forme :Yellow Crystals From Dil Methanol Or Ethanol SolidMasse moléculaire :448.38Cysmethynil
CAS :Cysmethynil is an indole-based Icmt inhibitor with antitumor activity, induces cell cycle arrest in G1 phase, and can be used for the study of solid tumors.Formule :C25H32N2ODegré de pureté :99%Couleur et forme :SolidMasse moléculaire :376.53Ref: TM-T36082
1mg47,00€2mg60,00€5mg87,00€10mg140,00€25mg274,00€50mg439,00€100mg707,00€500mg1.415,00€Dehydropachymic acid
CAS :Dehydropachymic acid shows antiinflammatory activity.Formule :C33H50O5Degré de pureté :98.22% - 99.78%Couleur et forme :SolidMasse moléculaire :526.75Crizotinib hydrochloride
CAS :Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)Formule :C21H23Cl3FN5ODegré de pureté :98.73% - 98.87%Couleur et forme :SolidMasse moléculaire :486.8Ref: TM-T8399
5mg37,00€10mg52,00€25mg82,00€50mg99,00€100mg138,00€200mg171,00€500mg227,00€1mL*10mM (DMSO)59,00€Dactolisib
CAS :Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).Formule :C30H23N5ODegré de pureté :97.64% - 99.85%Couleur et forme :SolidMasse moléculaire :469.54Salirasib
CAS :Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.Formule :C22H30O2SDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :358.54Ref: TM-T6163
5mg35,00€10mg52,00€25mg96,00€50mg159,00€100mg221,00€200mg364,00€500mg597,00€1mL*10mM (DMSO)59,00€Apostatin-1
CAS :Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.Formule :C19H27N3OSDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :345.5Ref: TM-T9079
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg235,00€50mg378,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)87,00€Pepstatin
CAS :Pepstatin (Pepsin Inhibitor S 735A) is a specific and orally aspartate protease inhibitor that also inhibits HIV protease activity. Cost effective and quality assured.Formule :C34H63N5O9Degré de pureté :96.74% - 99.94%Couleur et forme :SolidMasse moléculaire :685.89Hydroxyprogesterone caproate
CAS :Hydroxyprogesterone caproate (Delalutin) is a synthetic progestin that activates progesterone receptors and inhibits ovulation.Formule :C27H40O4Degré de pureté :99.70%Couleur et forme :White Or Almost White Crystalline PowerMasse moléculaire :428.6(E)-Daporinad
CAS :(E)-Daporinad (FK866) is a highly specific, non-competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .Cost-effective and quality-assured.Formule :C24H29N3O2Degré de pureté :100% - 99.96%Couleur et forme :SolidMasse moléculaire :391.51Ref: TM-T2644
2mg43,00€5mg65,00€10mg96,00€25mg188,00€50mg368,00€100mg557,00€500mg1.169,00€1mL*10mM (DMSO)70,00€Glucosamine hydrochloride
CAS :Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.Formule :C6H13NO5·HClDegré de pureté :99.77%Couleur et forme :White Solid CrystallineMasse moléculaire :215.63SR9009
CAS :SR9009, a REV-ERB agonist, modulates genes and circadian rhythms, reducing fat mass and improving metabolism in obese mice.Formule :C20H24ClN3O4SDegré de pureté :99.53% - 99.8%Couleur et forme :SolidMasse moléculaire :437.94Daunorubicin hydrochloride
CAS :Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and proteinFormule :C27H29NO10·HClDegré de pureté :96.21% - 99.53%Couleur et forme :Cancer DrugMasse moléculaire :563.99Ref: TM-T1511
5mg37,00€10mg56,00€25mg92,00€50mg119,00€100mg187,00€200mg298,00€500mg467,00€1mL*10mM (DMSO)63,00€Dorsomorphin
CAS :Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.Formule :C24H25N5ODegré de pureté :98% - 99.06%Couleur et forme :SolidMasse moléculaire :399.49740 Y-P
CAS :740 Y-P (740YPDGFR) is a potent and cell-permeable activator of PI3K.Formule :C141H222N43O39PS3Degré de pureté :98.3% - 99.87%Couleur et forme :SolidMasse moléculaire :3270.7S29434
CAS :S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).Formule :C21H18N4O3Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :374.39Telmisartan
CAS :Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.Formule :C33H30N4O2Degré de pureté :99.88% - 99.96%Couleur et forme :White Or Off White Crystalline PowderMasse moléculaire :514.62VO-Ohpic trihydrate
CAS :VO-Ohpic trihydrate (VO-Ohpic) is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.Formule :C12H9N2O8V·3H2O·HDegré de pureté :100%Couleur et forme :SolidMasse moléculaire :415.2Samotolisib
CAS :Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.Formule :C23H26N4O3Degré de pureté :98.41% - 99.69%Couleur et forme :SolidMasse moléculaire :406.48Vinblastine sulfate
CAS :Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).Formule :C46H58N4O9·H2SO4Degré de pureté :97.81% - 99.38%Couleur et forme :White PowderMasse moléculaire :909.06Isodeoxyelephantopin
CAS :Isodeoxyelephantopin can inhibit the growth of various tumor cells.Formule :C19H20O6Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :344.36Lonafarnib
CAS :Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).Formule :C27H31Br2ClN4O2Degré de pureté :98% - 99.04%Couleur et forme :SolidMasse moléculaire :638.82Taurine
CAS :Taurine (2-Aminoethanesulfonic acid) is an organic acid widely distributed in animal tissues and is one of the constituents of bile acids. Cost-effective and quality-assured.Formule :C2H7NO3SDegré de pureté :98.05% - 99.81%Couleur et forme :White Crystalline PowderMasse moléculaire :125.15PD146176
CAS :PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.Formule :C15H11NSDegré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :237.32SR9011
CAS :SR9011 is a REV-ERB agonist (IC50: 790 nM, REV-ERBα; IC50: 560 nM, REV-ERBβ).Formule :C23H31ClN4O3SDegré de pureté :99.64% - 99.65%Couleur et forme :SolidMasse moléculaire :479.04Tenovin-6
CAS :Tenovin-6 is a p53 transcriptional activity agonist.Formule :C25H34N4O2SDegré de pureté :100% - 97.71%Couleur et forme :SolidMasse moléculaire :454.63Ref: TM-T1818
1mg43,00€2mg56,00€5mg77,00€10mg87,00€25mg157,00€50mg230,00€100mg393,00€500mg930,00€1mL*10mM (DMSO)79,00€NBDHEX
CAS :NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).Formule :C12H15N3O4SDegré de pureté :97.38%Couleur et forme :SolidMasse moléculaire :297.33Gemcitabine hydrochloride
CAS :Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formule :C9H11F2N3O4·HClDegré de pureté :99.28% - 99.98%Couleur et forme :White Crystalline Granular OdorlessMasse moléculaire :299.66Lovastatin
CAS :Lovastatin (MK-803) is an HMG-CoA reductase inhibitor. Lovastatin lowers cholesterol and is used as a lipid-lowering agent. Cost-effective and quality-assured.Formule :C24H36O5Degré de pureté :99.59% - 99.72%Couleur et forme :The Substance Is A White-Yellowish To Yellow Powder Solid PowderMasse moléculaire :404.54CFTR(inh)-172
CAS :CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.Formule :C18H10F3NO3S2Degré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :409.4Ref: TM-T2355
1mg35,00€2mg46,00€5mg66,00€10mg97,00€25mg188,00€50mg359,00€100mg530,00€1mL*10mM (DMSO)69,00€Cilengitide TFA
CAS :Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.Formule :C29H41F3N8O9Couleur et forme :SolidMasse moléculaire :702.68Wogonoside
CAS :Wogonoside (Wogonin 7-O-glucuronide) acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.Formule :C22H20O11Degré de pureté :98.24% - 98.66%Couleur et forme :SolidMasse moléculaire :460.39KAN0438757
CAS :KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.Formule :C21H18FNO7SDegré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :447.43Ref: TM-T11741
1mg101,00€5mg192,00€10mg306,00€25mg553,00€50mg760,00€100mg1.035,00€1mL*10mM (DMSO)207,00€PF-3845
CAS :PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.Formule :C24H23F3N4O2Degré de pureté :99.54% - 99.58%Couleur et forme :SolidMasse moléculaire :456.46Ref: TM-T6043
2mg42,00€5mg59,00€10mg97,00€25mg205,00€50mg354,00€100mg560,00€200mg800,00€1mL*10mM (DMSO)59,00€Genipin
CAS :Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.Formule :C11H14O5Degré de pureté :99.09% - 99.21%Couleur et forme :SolidMasse moléculaire :226.23SAR405
CAS :SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.Formule :C19H21ClF3N5O2Degré de pureté :99.42% - 99.79%Couleur et forme :SolidMasse moléculaire :443.85Ref: TM-T12831L
1mg149,00€2mg217,00€5mg368,00€10mg580,00€25mg882,00€50mg1.596,00€1mL*10mM (DMSO)444,00€Azithromycin hydrate
CAS :Azithromycin hydrate (CP-62993 dihydrate) is a semi-synthetic macrolide antibiotic structurally related to erythromycin.Formule :C38H72N2O12·2H2ODegré de pureté :99.83% - 99.92%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :785.03Clioquinol
CAS :Clioquinol: oral, lipophilic copper-binder; halogenated quinoline with antifungal, antiparasitic, and possible antitumor uses.Formule :C9H5ClINODegré de pureté :97.02%Couleur et forme :Brownish-Yellow Bulky Powder Decomposes At 178-179°C Used As A Topical Anti-InfectiveMasse moléculaire :305.5Chelerythrine chloride
CAS :Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFormule :C21H18ClNO4Degré de pureté :95% - 99.19%Couleur et forme :Yellow To Orange SolidMasse moléculaire :383.83Clematichinenoside AR
CAS :Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.Formule :C82H134O43Degré de pureté :99.49% - 99.69%Couleur et forme :SolidMasse moléculaire :1807.92ISOGINKGETIN
CAS :ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Formule :C32H22O10Degré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :566.51SF1670
CAS :SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM.Formule :C19H17NO3Degré de pureté :98.25% - 98.54%Couleur et forme :SolidMasse moléculaire :307.34Ref: TM-T6667
1mg44,00€2mg55,00€5mg88,00€10mg125,00€25mg273,00€50mg500,00€100mg740,00€1mL*10mM (DMSO)97,00€Idelalisib
CAS :Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM).Formule :C22H18FN7ODegré de pureté :98% - 99.39%Couleur et forme :SolidMasse moléculaire :415.42Ref: TM-T1894
5mg35,00€10mg50,00€25mg74,00€50mg93,00€100mg108,00€200mg140,00€500mg225,00€1mL*10mM (DMSO)52,00€Veliparib
CAS :Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.Formule :C13H16N4ODegré de pureté :98.66% - 99%Couleur et forme :SolidMasse moléculaire :244.29Ref: TM-T2591
5mg57,00€10mg81,00€25mg127,00€50mg207,00€100mg331,00€200mg540,00€500mg852,00€1mL*10mM (DMSO)64,00€Vancomycin
CAS :Vancomycin is a glycopeptide antibiotic that exerts its antimicrobial activity by altering the permeability of cell membranes and selectively inhibitingFormule :C66H75Cl2N9O24Degré de pureté :99.24%Couleur et forme :Almost White PowderMasse moléculaire :1449.25Vps34-IN-1
CAS :Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.Formule :C21H24ClN7ODegré de pureté :97.04%Couleur et forme :SolidMasse moléculaire :425.91Ref: TM-T7015
1mg46,00€2mg59,00€5mg93,00€10mg131,00€25mg219,00€50mg350,00€100mg505,00€1mL*10mM (DMSO)92,00€ST-539
CAS :ST-539 is an inhibitor of the deubiquitinating enzyme USP30, with an IC50 of 0.37 μM. It enhances the ubiquitination of mitochondrial proteins and induces mitophagy (autophagy), thereby regulating mitochondrial homeostasis. ST-539 is applicable for research in neurodegenerative diseases.Formule :C30H31N3O4SCouleur et forme :SolidMasse moléculaire :529.65
