Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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Panobinostat
CAS :Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.Formule :C21H23N3O2Degré de pureté :97.2% - 99.14%Couleur et forme :Yellow SolidMasse moléculaire :349.43Ref: TM-T2383
5mg38,00€10mg57,00€25mg87,00€50mg105,00€100mg144,00€200mg177,00€500mg364,00€1mL*10mM (DMSO)55,00€Kaempferol
CAS :Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.Formule :C15H10O6Degré de pureté :98% - 99.41%Couleur et forme :Yellow Needles From Alcohol And Water SolidMasse moléculaire :286.24Ref: TM-T2177
1g274,00€5mg52,00€25mg39,00€50mg50,00€100mg64,00€200mg89,00€500mg187,00€1mL*10mM (DMSO)55,00€Meglutol
CAS :Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.Formule :C6H10O5Degré de pureté :99.73% - 99.94%Couleur et forme :SolidMasse moléculaire :162.14Capivasertib
CAS :Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.Formule :C21H25ClN6O2Degré de pureté :97.59% - 99.6%Couleur et forme :SolidMasse moléculaire :428.92Ref: TM-T1920
1mg40,00€2mg52,00€5mg70,00€10mg99,00€25mg168,00€50mg246,00€100mg378,00€200mg610,00€1mL*10mM (DMSO)89,00€Trifluoperazine
CAS :Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.Formule :C21H24F3N3SDegré de pureté :98.3% - 99.46%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :407.5Erlotinib hydrochloride
CAS :Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formule :C22H23N3O4·HClDegré de pureté :99.78% - 99.85%Couleur et forme :White Or Off-White PowderMasse moléculaire :429.9Oxyresveratrol
CAS :1.Formule :C14H12O4Degré de pureté :98.09% - 99.69%Couleur et forme :Yellow SolidMasse moléculaire :244.24Sodium 4-phenylbutyrate
CAS :Sodium 4-phenylbutyrate (TriButyrate), a transcriptional regulator, reversibly inhibits class I and II HDACs resulting in a global increase in gene expression.Formule :C10H11NaO2Degré de pureté :100% - 99.92%Couleur et forme :SolidMasse moléculaire :186.18Resveratrol
CAS :Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities.Formule :C14H12O3Degré de pureté :99.53% - 99.9%Couleur et forme :Off-White To Tan PowderMasse moléculaire :228.24Dronedarone hydrochloride
CAS :Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.Formule :C31H44N2O5S·HClDegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :593.22Ref: TM-T1073
5mg38,00€10mg52,00€25mg87,00€50mg117,00€100mg170,00€200mg250,00€500mg424,00€1mL*10mM (DMSO)55,00€Flavopiridol
CAS :Flavopiridol (Alvocidib) blocks CDK1/2/4/6 by competing with ATP (IC50 ~40 nM); 7.5x selectivity over CDK7; also inhibits EGFR, PKA. In Phase 1/2 trials.Formule :C21H20ClNO5Degré de pureté :97.74% - 99.86%Couleur et forme :SolidMasse moléculaire :401.84SU9516
CAS :SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.Formule :C13H11N3O2Degré de pureté :100% - 99.68%Couleur et forme :SolidMasse moléculaire :241.25Ref: TM-T6167
1mg35,00€2mg50,00€5mg73,00€10mg103,00€25mg208,00€50mg376,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)74,00€Dehydrocorydaline nitrate
CAS :DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formule :C22H24N2O7Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :428.44A-867744
CAS :A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).Formule :C20H19ClN2O3SDegré de pureté :95.66%Couleur et forme :SolidMasse moléculaire :402.89MG-132
CAS :View and buy MG-132 from TargetMol.MG-132 is a potent cell-permeable 26S proteasome inhibitor (IC50: 100 nM). It also inhibits calpain (IC50: 1.2 μM).Cited in 50 publications.Formule :C26H41N3O5Degré de pureté :95% - 99.99%Couleur et forme :White To Off-White PowderMasse moléculaire :475.62Ref: TM-T2154
10mg48,00€25mg88,00€50mg144,00€100mg216,00€200mg376,00€500mg472,00€1mL*10mM (DMSO)47,00€KN-93
CAS :KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.Formule :C26H29ClN2O4SDegré de pureté :99.78% - 99.86%Couleur et forme :White SolidMasse moléculaire :501.04Ref: TM-T2697
1mg57,00€2mg79,00€5mg113,00€10mg155,00€25mg305,00€50mg378,00€100mg552,00€1mL*10mM (DMSO)127,00€Rhoifolin
CAS :Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Formule :C27H30O14Degré de pureté :98.11% - 98.87%Couleur et forme :SolidMasse moléculaire :578.52BGT226
CAS :BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.Formule :C28H25F3N6O2Degré de pureté :100% - 98.40%Couleur et forme :SolidMasse moléculaire :534.53Ref: TM-T6072L
1mg52,00€5mg114,00€10mg187,00€25mg411,00€50mg607,00€100mg847,00€1mL*10mM (DMSO)156,00€Corynoxine
CAS :Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.Formule :C22H28N2O4Degré de pureté :96.83% - 99.93%Couleur et forme :SolidMasse moléculaire :384.47Talarozole
CAS :Talarozole is an oral RAMBA for treating acne and psoriasis, inhibiting CYP26A1/26B1 with IC50s of 5.4/0.46 nM.Formule :C21H23N5SDegré de pureté :97.51%Couleur et forme :SolidMasse moléculaire :377.5110058-F4
CAS :10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.Formule :C12H11NOS2Degré de pureté :98% - 99.82%Couleur et forme :SolidMasse moléculaire :249.35BGT226 maleate
CAS :BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .Formule :C28H25F3N6O2·C4H4O4Degré de pureté :97.75% - 98.78%Couleur et forme :SolidMasse moléculaire :650.6Ref: TM-T6072
1mg38,00€5mg77,00€10mg114,00€25mg244,00€50mg359,00€100mg512,00€200mg702,00€1mL*10mM (DMSO)99,00€Schizandrin A
CAS :Schisandrin A, a primary active component extracted from the traditional Eastern medicine Schisandra chinensis, inhibits CYP3A activity, with an IC50 of 6.60 μMFormule :C24H32O6Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :416.51Isoalantolactone
CAS :Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.Formule :C15H20O2Degré de pureté :99.75% - 99.94%Couleur et forme :SolidMasse moléculaire :232.32SMER18
CAS :SMER18, a small molecule enhancer of rapamycin, acts as an mTOR-independent inducer of autophagy and can be used to study neurodegenerative diseases.Formule :C16H14ClNO2Degré de pureté :97.27%Couleur et forme :SolidMasse moléculaire :287.74Ref: TM-T16900
1mg133,00€5mg329,00€10mg472,00€25mg914,00€50mg1.415,00€100mg1.882,00€1mL*10mM (DMSO)360,00€Salvigenin
CAS :Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.Formule :C18H16O6Degré de pureté :99.17% - 99.67%Couleur et forme :SolidMasse moléculaire :328.32Adapalene
CAS :Adapalene (CD271) is a dual RAR and RXR agonist, utilized in the treatment of skin conditions.Formule :C28H28O3Degré de pureté :99.53% - 99.76%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :412.52Gemcitabine
CAS :Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formule :C9H11F2N3O4Degré de pureté :100% - 99.67%Couleur et forme :SolidMasse moléculaire :263.2Ixazomib
CAS :Ixazomib (MLN2238) is a boron-based peptide proteasome inhibitor targeting β5 site (IC50: 3.4 nM), also affecting β1 and β2 sites.Formule :C14H19BCl2N2O4Degré de pureté :98% - 98.92%Couleur et forme :SolidMasse moléculaire :361.03Ref: TM-T2122
1mg48,00€5mg95,00€10mg127,00€25mg259,00€50mg416,00€100mg652,00€200mg922,00€1mL*10mM (DMSO)97,00€Efavirenz
CAS :Efavirenz (DMP 266) is an HIV-1 inhibitor, affecting reverse transcriptase and various cytochrome P450 enzymes.Formule :C14H9ClF3NO2Degré de pureté :99.2% - 99.83%Couleur et forme :White To Slightly Pink Crystalline PowderMasse moléculaire :315.67Ref: TM-T2393
1g404,00€5mg42,00€10mg52,00€25mg71,00€50mg89,00€100mg116,00€500mg273,00€1mL*10mM (DMSO)49,00€Acitretin
CAS :Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.Formule :C21H26O3Degré de pureté :100% - 98.60%Couleur et forme :Crystals From Hexane SolidMasse moléculaire :326.43DMH-1
CAS :DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.Formule :C24H20N4ODegré de pureté :98% - 99.92%Couleur et forme :SolidMasse moléculaire :380.44Alisertib
CAS :Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.Formule :C27H20ClFN4O4Degré de pureté :100% - 99.82%Couleur et forme :SolidMasse moléculaire :518.92Ref: TM-T2241
5mg55,00€10mg96,00€25mg155,00€50mg226,00€100mg354,00€200mg454,00€500mg743,00€1mL*10mM (DMSO)63,00€CHIR-99021
CAS :View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.Formule :C22H18Cl2N8Degré de pureté :97.94% - ≥95%Couleur et forme :SolidMasse moléculaire :465.34Ref: TM-T2310
2mg43,00€5mg64,00€10mg96,00€25mg160,00€50mg254,00€100mg404,00€200mg603,00€500mg938,00€1mL*10mM (DMSO)70,00€Loperamide hydrochloride
CAS :Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.Formule :C29H34Cl2N2O2Degré de pureté :100% - 99.94%Couleur et forme :Crystals Practically Insoluble In WaterMasse moléculaire :513.498Colchicine
CAS :Colchicine (Colcin) is a natural product that is an inhibitor of microtubule polymerization (IC50=3 nM) and blocks microtubule polymerization by binding toFormule :C22H25NO6Degré de pureté :98% - 99.96%Couleur et forme :Pale Yellow Scales Or Powder; Pale Yellow Needles When Crystallized From Ethyl Acetate To Light Used To Treat Gouty Arthritis Pseudogout Sarcoidal Arthritis And Calcific Tendinitis (EpaMasse moléculaire :399.44Lomustine
CAS :Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.Formule :C9H16ClN3O2Degré de pureté :98.36% - 99.44%Couleur et forme :Solid SolidMasse moléculaire :233.7Tempol
CAS :Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.Formule :C9H18NO2Degré de pureté :97% - 99.74%Couleur et forme :4-Hydroxy-Tempo Appears As Orange Flakes Solid FlakesMasse moléculaire :172.25Tanespimycin
CAS :Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).Formule :C31H43N3O8Degré de pureté :99.07% - 99.83%Couleur et forme :Dark Purple SolidMasse moléculaire :585.69Sedanolide
CAS :Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery.Formule :C12H18O2Degré de pureté :97.14% - ≥98%Couleur et forme :SolidMasse moléculaire :194.27α-Thujone
CAS :α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.Formule :C10H16ODegré de pureté :98.16% - 98.41%Couleur et forme :Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Masse moléculaire :152.23GSK621
CAS :GSK621 is a specific and potent AMPK activator.Formule :C26H20ClN3O5Degré de pureté :97.02% - 97.05%Couleur et forme :SolidMasse moléculaire :489.91DMOG
CAS :DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.Formule :C6H9NO5Degré de pureté :80.23% - 99.98%Couleur et forme :SolidMasse moléculaire :175.14ZLN005
CAS :ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.Formule :C17H18N2Degré de pureté :100% - 99.8%Couleur et forme :SolidMasse moléculaire :250.34Ref: TM-T1802
5mg37,00€10mg56,00€25mg90,00€50mg170,00€100mg274,00€200mg411,00€500mg653,00€1mL*10mM (DMSO)40,00€Carprofen
CAS :Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities.Formule :C15H12ClNO2Degré de pureté :98.99% - 99.65%Couleur et forme :SolidMasse moléculaire :273.71Autogramin-1
CAS :Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM.Formule :C23H27N5O5SDegré de pureté :97.22% - 98.76%Couleur et forme :SolidMasse moléculaire :485.56Vitexin
CAS :Vitexin: antinociceptive, antispasmodic, antioxidant, affects CYP enzymes, may inhibit cancer metastasis, protects brain.Formule :C21H20O10Degré de pureté :99.16% - 99.64%Couleur et forme :Yellow PowderMasse moléculaire :432.38Lithocholic acid
CAS :Lithocholic acid, a bile acid, aids fat absorption, often paired with glycine/taurine, and promotes bile flow.Formule :C24H40O3Degré de pureté :99.69% - 99.93%Couleur et forme :Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Masse moléculaire :376.57BIX-01294
CAS :BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).Formule :C28H38N6O2Degré de pureté :99.31% - 99.64%Couleur et forme :SolidMasse moléculaire :490.64Ref: TM-T7697
1mg40,00€2mg51,00€5mg85,00€10mg117,00€25mg207,00€50mg350,00€100mg518,00€200mg740,00€1mL*10mM (DMSO)131,00€Colistin sulfate
CAS :Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.Formule :C53H100N16O17SDegré de pureté :≥95%Couleur et forme :PowderMasse moléculaire :1253.51Silibinin
CAS :Silibinin, main component in milk thistle, offers liver protection and shows anti-cancer potential in various human cells.Formule :C25H22O10Degré de pureté :97.98% - 98.35%Couleur et forme :SolidMasse moléculaire :482.44Oroxin B
CAS :Oroxin B (Hypocretin-2) has antioxidant activity.Formule :C27H30O15Degré de pureté :98.22% - 98.33%Couleur et forme :SolidMasse moléculaire :594.52Pictilisib
CAS :Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).Formule :C23H27N7O3S2Degré de pureté :99% - 99.97%Couleur et forme :SolidMasse moléculaire :513.64BC1618
CAS :BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.Formule :C24H24F3NO2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :415.45SR12813
CAS :SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.Formule :C24H42O7P2Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :504.53Ipsalazide
CAS :Ipsalazide is a novel salicylazosulfapyridine analog for the treatment of inflammatory bowel disease.Formule :C16H11N3Na2O6Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :387.25DBEQ
CAS :DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.Formule :C22H20N4Degré de pureté :98.89% - ≥95%Couleur et forme :SolidMasse moléculaire :340.42Ref: TM-T1969
5mg58,00€10mg95,00€25mg180,00€50mg324,00€100mg410,00€200mg607,00€500mg938,00€1mL*10mM (DMSO)59,00€VLX600
CAS :VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent.Formule :C17H15N7Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :317.35HDAC10-IN-2 hydrochloride
HDAC10-IN-2 hydrochloride (compound 10c) is an HDAC10 inhibitor with high potency and selectivity, exhibiting an IC50 of 20 nM.Formule :C19H23ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :346.85Carfilzomib
CAS :Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Formule :C40H57N5O7Degré de pureté :99.6% - 99.84%Couleur et forme :SolidMasse moléculaire :719.91Shogaol
CAS :6-Shogaol: anti-inflammatory, analgesic, antipyretic, protects cartilage, arrests cancer cell growth, inhibits metastasis.Formule :C17H24O3Degré de pureté :98.26% - 99.39%Couleur et forme :SolidMasse moléculaire :276.37Ref: TM-T6S1699
2mg43,00€5mg62,00€10mg92,00€25mg180,00€50mg283,00€100mg432,00€500mg938,00€1mL*10mM (DMSO)67,00€PF-04457845
CAS :PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).Formule :C23H20F3N5O2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :455.43Ref: TM-T4323
2mg35,00€5mg52,00€10mg88,00€25mg163,00€50mg235,00€100mg419,00€200mg545,00€1mL*10mM (DMSO)58,00€Dansylcadaverine
CAS :Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe.Formule :C17H25N3O2SDegré de pureté :98.33% - 98.99%Couleur et forme :SolidMasse moléculaire :335.46PF-04691502
CAS :PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.Formule :C22H27N5O4Degré de pureté :96.27% - ≥95%Couleur et forme :SolidMasse moléculaire :425.48Sinomenine hydrochloride
CAS :Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.Formule :C19H24ClNO4Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :365.851Fenretinide
CAS :Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.Formule :C26H33NO2Degré de pureté :98% - 99.72%Couleur et forme :Yellow PowderMasse moléculaire :391.55AZ304
CAS :AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).Formule :C27H25N5O2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :451.52MHY1485
CAS :MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, thereby inhibiting autophagy. Cost-effective and quality-assured.Formule :C17H21N7O4Degré de pureté :100% - 99.6%Couleur et forme :SolidMasse moléculaire :387.39Lapatinib
CAS :Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.Formule :C29H26ClFN4O4SDegré de pureté :99.00% - 99.81%Couleur et forme :PowderMasse moléculaire :581.06PHY34
CAS :PHY34 inhibits autophagy at nanomolar potency, with anti-tumor effects on HGSOC in vivo.Formule :C30H30O12Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :582.55Ref: TM-T37376
1mg164,00€2mg235,00€5mg369,00€10mg548,00€25mg879,00€50mg1.198,00€100mg1.596,00€500mg3.212,00€JNJ-42165279
CAS :JNJ-42165279 selectively inactivates FAAH without notably affecting other enzymes, ion channels, receptors, or CYPs/hERG at 10 μM.Formule :C18H17ClF2N4O3Degré de pureté :99.88% - 99.89%Couleur et forme :SolidMasse moléculaire :410.8Ref: TM-T3215
2mg46,00€5mg65,00€10mg96,00€25mg170,00€50mg246,00€100mg363,00€200mg512,00€1mL*10mM (DMSO)75,00€Saracatinib
CAS :Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Formule :C27H32ClN5O5Degré de pureté :98% - 99.63%Couleur et forme :SolidMasse moléculaire :542.03ZX-29
CAS :ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.Formule :C23H28ClN7O3SDegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :518.03Ref: TM-T13416
1mg92,00€5mg230,00€10mg364,00€25mg620,00€50mg848,00€100mg1.121,00€1mL*10mM (DMSO)296,00€Berbamine dihydrochloride
CAS :Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.Formule :C37H42Cl2N2O6Degré de pureté :95% - 99.38%Couleur et forme :SolidMasse moléculaire :681.65Chloroquine
CAS :Chloroquine: antimalarial, anti-inflammatory, autophagy/TLRs inhibitor, treats arthritis, effective against COVID-19 in vitro. EC50: 1.13 μM.Formule :C18H26ClN3Degré de pureté :99.82% - 99.98%Couleur et forme :White To Slightly Yellow Crystalline Powder SolidMasse moléculaire :319.875-Aminolevulinic acid hydrochloride
CAS :5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.Formule :C5H10ClNO3Degré de pureté :98% - 99.97%Couleur et forme :White To Pale Yellow Crystals OrMasse moléculaire :167.59ULK-101
CAS :ULK-101 is a potent and selective ULK1 inhibitor ( IC50s: 8.3/30 nM for ULK1/ULK2). It can suppress autophagy.Formule :C22H16F4N4OSDegré de pureté :97.55% - 99.66%Couleur et forme :SolidMasse moléculaire :460.45Ref: TM-T5403
1mg111,00€5mg274,00€10mg432,00€25mg747,00€50mg1.121,00€100mg1.510,00€1mL*10mM (DMSO)279,00€Tolvaptan
CAS :Tolvaptan (OPC-41061) is an orally bioavailable, selective, arginine vasopressin receptor 2 (V2, AVPR2) antagonist that can be used to treat hyponatremia.Formule :C26H25ClN2O3Degré de pureté :97% - 99.91%Couleur et forme :SolidMasse moléculaire :448.94ALA-A2 peptide
ALA-A2, a cancer peptide found in α-lactalbumin, selectively kills cancer cells by inducing autophagy (Autophagy). It possesses cell-penetrating properties, allowing it to enter cells effectively without relying on membrane solubilization effects. In A549 lung cancer cells, ALA-A2 demonstrates significant dose-dependent anticancer activity. This peptide shows promise for research in cancer treatment and autophagy regulation.Formule :C67H111N21O19SCouleur et forme :SolidMasse moléculaire :1546.79GCN2iB
CAS :GCN2iB is an ATP-competitive inhibitor of serine/threonine protein kinase, stress-responsive kinase (GCN2).Cost-effective and quality-assured.Formule :C18H12ClF2N5O3SDegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :451.83Ref: TM-T11375
1mg85,00€5mg170,00€10mg274,00€25mg547,00€50mg783,00€100mg1.074,00€1mL*10mM (DMSO)187,00€Sepantronium bromide
CAS :Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.Formule :C20H19BrN4O3Degré de pureté :99.68% - 99.82%Couleur et forme :SolidMasse moléculaire :443.26Mirdametinib
CAS :Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.Formule :C16H14F3IN2O4Degré de pureté :99.18% - 99.63%Couleur et forme :White PowderMasse moléculaire :482.19Ref: TM-T6189
1g898,00€5mg51,00€10mg74,00€25mg127,00€50mg175,00€100mg273,00€200mg406,00€500mg662,00€1mL*10mM (DMSO)55,00€Ligustilide
CAS :3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.Formule :C12H14O2Degré de pureté :96.03% - 98.14%Couleur et forme :Yellow Brown PowderMasse moléculaire :190.24Nilotinib monohydrochloride monohydrate
CAS :Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosineFormule :C28H22F3N7O·HCl·H2ODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :583.99Vorinostat
CAS :Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11.Formule :C14H20N2O3Degré de pureté :99.47% - 99.65%Couleur et forme :White Crystalline SolidMasse moléculaire :264.32Isradipine
CAS :Isradipine (PN 200-110), a dihydropyridine, is an antihypertensive calcium channel blocker that dilates arteries and reduces resistance.Formule :C19H21N3O5Degré de pureté :99.65% - 99.84%Couleur et forme :Yellow SolidMasse moléculaire :371.39LRRK2-IN-1
CAS :LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.Formule :C31H38N8O3Degré de pureté :98% - 98.82%Couleur et forme :SolidMasse moléculaire :570.69TG101209
CAS :TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formule :C26H35N7O2SDegré de pureté :100% - 99.36%Couleur et forme :SolidMasse moléculaire :509.67SR-18292
CAS :SR-18292 inhibits PGC-1α, enhances acetylation, lowers gluconeogenesis, and cuts hepatic glucose production.Formule :C23H30N2O2Degré de pureté :99% - 99.36%Couleur et forme :SolidMasse moléculaire :366.5Ref: TM-T4353
2mg40,00€5mg60,00€10mg87,00€25mg180,00€50mg283,00€100mg449,00€500mg938,00€1mL*10mM (DMSO)71,00€Mito-LND
CAS :Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.Formule :C43H45BrCl2N3OPDegré de pureté :97.25% - 98.34%Couleur et forme :SolidMasse moléculaire :801.62MRT68921 HCl
CAS :MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM, respectively).Formule :C25H34N6O·HClDegré de pureté :99.86% - 99.98%Couleur et forme :SolidMasse moléculaire :471.04GW786034B
CAS :Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formule :C21H23N7O2S·HClDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :473.98Ref: TM-T6930
10mg52,00€25mg90,00€50mg96,00€100mg140,00€200mg229,00€500mg359,00€1mL*10mM (DMSO)52,00€Fexaramine
CAS :Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.Formule :C32H36N2O3Degré de pureté :98.87% - 99.61%Couleur et forme :SolidMasse moléculaire :496.64Danusertib
CAS :Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Formule :C26H30N6O3Degré de pureté :97.88% - 98.44%Couleur et forme :White PowderMasse moléculaire :474.55Ref: TM-T2094
1mg59,00€2mg85,00€5mg116,00€10mg188,00€25mg365,00€50mg555,00€100mg795,00€500mg1.605,00€1mL*10mM (DMSO)120,00€UNBS5162
CAS :UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.Formule :C17H18N4O3Degré de pureté :98.37% - 99.97%Couleur et forme :SolidMasse moléculaire :326.35Ref: TM-T2477
1mg39,00€5mg81,00€10mg116,00€25mg215,00€50mg340,00€100mg540,00€200mg787,00€1mL*10mM (DMSO)89,00€PFK-015
CAS :PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).Formule :C17H12N2ODegré de pureté :98.94% - 99.7%Couleur et forme :SolidMasse moléculaire :260.29Ref: TM-T2455
5mg57,00€10mg88,00€25mg159,00€50mg283,00€100mg419,00€200mg582,00€500mg928,00€1mL*10mM (DMSO)57,00€TPEN
CAS :TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.Formule :C26H28N6Degré de pureté :98% - 99.72%Couleur et forme :White Crystalline PowderMasse moléculaire :424.54Gemcitabine elaidate
CAS :Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, withFormule :C27H43F2N3O5Couleur et forme :SolidMasse moléculaire :527.64FB49
FB49 is a selective Bcl-2-associated athanogene 3 (BAG3) inhibitor with a Ki of 45 μM.Formule :C17H18N2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.4Vandetanib
CAS :Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formule :C22H24BrFN4O2Degré de pureté :100% - 99.84%Couleur et forme :White SolidMasse moléculaire :475.35Ref: TM-T1656
10mg49,00€25mg69,00€50mg97,00€100mg170,00€200mg235,00€500mg379,00€1mL*10mM (DMSO)55,00€
