Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
Produits appartenant à la catégorie "Autophagie"
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VISTA-IN-2
CAS :VISTA-IN-2 (Compound 1) is a V-domain Ig suppressor of T-cell activation (VISTA) inhibitor that promotes the degradation of VISTA in cells via autophagy,Formule :C23H23N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :357.45Reversine
CAS :Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).Formule :C21H27N7ODegré de pureté :98% - 99.75%Couleur et forme :SolidMasse moléculaire :393.49Ref: TM-T1825
1mg38,00€2mg49,00€5mg70,00€10mg88,00€25mg164,00€50mg224,00€100mg393,00€1mL*10mM (DMSO)70,00€TA-01
CAS :TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.Formule :C20H12F3N3Degré de pureté :98.77% - 99.94%Couleur et forme :SolidMasse moléculaire :351.32Ref: TM-T4645
2mg35,00€5mg52,00€10mg85,00€25mg156,00€50mg235,00€100mg329,00€200mg464,00€1mL*10mM (DMSO)71,00€10074-G5
CAS :10074-G5 is an inhibitor of c-Myc-Max dimerization.Formule :C18H12N4O3Degré de pureté :97.22% - 99.67%Couleur et forme :SolidMasse moléculaire :332.31Ref: TM-T3686
2mg42,00€5mg63,00€10mg88,00€25mg142,00€50mg225,00€100mg396,00€200mg565,00€500mg900,00€1mL*10mM (DMSO)69,00€Temozolomide
CAS :Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity.Formule :C6H6N6O2Degré de pureté :98% - 99.87%Couleur et forme :Off-White To Light-Pink Crystalline SolidMasse moléculaire :194.15Ref: TM-T1178
1g236,00€10mg49,00€25mg74,00€50mg89,00€100mg96,00€200mg127,00€500mg166,00€1mL*10mM (DMSO)59,00€Neferine
CAS :Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formule :C38H44N2O6Degré de pureté :98.81% - 99.18%Couleur et forme :SolidMasse moléculaire :624.77Metyrapone
CAS :Metyrapone (NSC-25265) blocks steroid 11β-monooxygenase, used to diagnose Cushing's syndrome.Formule :C14H14N2ODegré de pureté :99.03% - ≥95%Couleur et forme :Crystals From Ether & Pentane SolidMasse moléculaire :226.27Afzelin
CAS :Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-Formule :C21H20O10Degré de pureté :98.92% - 99.38%Couleur et forme :SolidMasse moléculaire :432.38DCC-3116
CAS :DCC-3116 is an orally active, selective and potent ULK1/2 inhibitor with anticancer activity.DCC-3116 inhibits autophagy and can be used in cancer research.Formule :C26H36F3N7O2Degré de pureté :98.80%Couleur et forme :SoildMasse moléculaire :535.61Autocamtide-2-related inhibitory peptide
CAS :Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.Formule :C64H116N22O19Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :1497.74Nitroxoline
CAS :Nitroxoline (5-nitroquinolin-8-ol) is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found inFormule :C9H6N2O3Degré de pureté :97.74% - ≥98%Couleur et forme :SolidMasse moléculaire :190.16Sertaconazole nitrate
CAS :Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.Formule :C20H15Cl3N2OS·HNO3Degré de pureté :98.66%Couleur et forme :SolidMasse moléculaire :500.78Silmitasertib
CAS :Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).Formule :C19H12ClN3O2Degré de pureté :98% - 99.90%Couleur et forme :SolidMasse moléculaire :349.77Ref: TM-T2259
1mg40,00€2mg51,00€5mg85,00€10mg125,00€25mg207,00€50mg329,00€100mg520,00€500mg1.111,00€1mL*10mM (DMSO)93,00€Necrostatin-1
CAS :Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Formule :C13H13N3OSDegré de pureté :100% - 99.81%Couleur et forme :SolidMasse moléculaire :259.33Ref: TM-T1847
5mg35,00€10mg49,00€25mg82,00€50mg113,00€100mg170,00€200mg250,00€500mg419,00€1mL*10mM (DMSO)52,00€Scutellarein
CAS :Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.Formule :C15H10O6Degré de pureté :98.02% - 99.63%Couleur et forme :SolidMasse moléculaire :286.24LY2183240
CAS :LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM).Formule :C17H17N5ODegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :307.35PF-543
CAS :PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.Formule :C27H31NO4SDegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :465.6Ref: TM-T6085
1mg50,00€5mg106,00€10mg156,00€25mg251,00€50mg374,00€100mg557,00€200mg903,00€1mL*10mM (DMSO)124,00€Lumacaftor
CAS :Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.Formule :C24H18F2N2O5Degré de pureté :99.48% - 99.68%Couleur et forme :SolidMasse moléculaire :452.41D4476
CAS :D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).Formule :C23H18N4O3Degré de pureté :99.02% - 99.96%Couleur et forme :SolidMasse moléculaire :398.41Ref: TM-T2449
1mg43,00€2mg55,00€5mg78,00€10mg95,00€25mg159,00€50mg226,00€100mg408,00€200mg597,00€500mg938,00€1mL*10mM (DMSO)86,00€Pennogenin 3-O-β-chacotrioside
CAS :Pennogenin 3-O-beta-chacotrioside from Paris polyphylla fights colorectal cancer, boosting autophagy proteins LC3 and Beclin-1.Formule :C45H72O17Degré de pureté :99.69% - 99.77%Couleur et forme :SolidMasse moléculaire :885.043PO
CAS :3PO inhibits PFKFB3 (IC50: 22.9 µM) and cancer cell growth (IC50: 1.4-24 µM), reducing glucose uptake and key cellular metabolites.Formule :C13H10N2ODegré de pureté :97.76% - 99.67%Couleur et forme :SolidMasse moléculaire :210.23Ref: TM-T22223
5mg57,00€10mg81,00€25mg127,00€50mg188,00€100mg340,00€200mg507,00€500mg807,00€1mL*10mM (DMSO)64,00€Emodin
CAS :Emodin, a plant-derived anthraquinone, inhibits Y cell growth via various signaling pathways.Formule :C15H10O5Degré de pureté :94.4% - 98.9%Couleur et forme :Physical Description Orange Needles Or Powder (Ntp 1992)Masse moléculaire :270.24Cucurbitacin B
CAS :Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formule :C32H46O8Degré de pureté :97.10% - 99.33%Couleur et forme :SolidMasse moléculaire :558.7EIPA
CAS :EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.Formule :C11H18ClN7ODegré de pureté :96.62% - 98.52%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :299.76Schisandrol B
CAS :Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.Formule :C23H28O7Degré de pureté :99.14% - 99.32%Couleur et forme :SolidMasse moléculaire :416.46Ref: TM-T6S1917
5mg71,00€10mg96,00€25mg202,00€50mg303,00€100mg452,00€500mg1.035,00€1mL*10mM (DMSO)79,00€Mdivi-1
CAS :Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).Formule :C15H10Cl2N2O2SDegré de pureté :96.57% - 99.6%Couleur et forme :SolidMasse moléculaire :353.22Ref: TM-T1907
5mg47,00€10mg56,00€25mg90,00€50mg153,00€100mg227,00€200mg338,00€500mg558,00€1mL*10mM (DMSO)50,00€Turofexorate Isopropyl
CAS :Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nMFormule :C25H24F2N2O3Degré de pureté :99.33% - 99.73%Couleur et forme :SolidMasse moléculaire :438.47ROC-325
CAS :ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.Formule :C28H27ClN4OSDegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :503.06Ref: TM-T16777
1mg35,00€2mg47,00€5mg64,00€10mg97,00€25mg188,00€50mg311,00€100mg449,00€500mgÀ demanderOlaparib
CAS :View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.Formule :C24H23FN4O3Degré de pureté :100% - 99.90%Couleur et forme :SolidMasse moléculaire :434.46Autophagy-IN-6
Autophagy-IN-6 (compound 1u) is an inhibitor of lysosomal autophagy that induces the accumulation of the LC3-II protein. Additionally, it exhibits antiproliferative activity.Formule :C28H43N3O3Couleur et forme :SolidMasse moléculaire :469.66MRT68921
CAS :MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.Formule :C25H34N6ODegré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :434.58Trimetazidine dihydrochloride
CAS :Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.Formule :C14H24Cl2N2O3Degré de pureté :99.58%Couleur et forme :Crystalline SolidMasse moléculaire :339.258Dexamethasone acetate
CAS :Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.Formule :C24H31FO6Degré de pureté :99.22% - 99.65%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :434.5Bardoxolone Methyl
CAS :Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-Formule :C32H43NO4Degré de pureté :97.81% - 99.09%Couleur et forme :SolidMasse moléculaire :505.69Ref: TM-T6165
10mg47,00€25mg65,00€50mg88,00€100mg119,00€200mg187,00€500mg424,00€1mL*10mM (DMSO)50,00€FIPI
CAS :FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.Formule :C23H24FN5O2Degré de pureté :98.01% - 99.08%Couleur et forme :SolidMasse moléculaire :421.47Etoposide
CAS :Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM).Formule :C29H32O13Degré de pureté :99.19% - 99.94%Couleur et forme :Crystals From Methanol SolidMasse moléculaire :588.56Diosgenin glucoside
CAS :Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosisFormule :C33H52O8Degré de pureté :97.17% - 99.44%Couleur et forme :SolidMasse moléculaire :576.76Leonurine
CAS :Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.Formule :C14H21N3O5Degré de pureté :98.55%Couleur et forme :White Crystalline PowderMasse moléculaire :311.33Pentoxifylline
CAS :Pentoxifylline (PTX) stimulates cytokines, inhibits phosphodiesterase, enhances blood flow, and increases cell flexibility.Formule :C13H18N4O3Degré de pureté :99.26% - 99.96%Couleur et forme :SolidMasse moléculaire :278.31UM-164
CAS :UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.Formule :C30H31F3N8O3SDegré de pureté :98.72% - 99.52%Couleur et forme :SolidMasse moléculaire :640.68CCT128930
CAS :'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'Formule :C18H20ClN5Degré de pureté :99.07% - 99.18%Couleur et forme :SolidMasse moléculaire :341.84Ref: TM-T6303
2mg42,00€5mg65,00€10mg94,00€25mg170,00€50mg273,00€100mg409,00€200mg652,00€1mL*10mM (DMSO)71,00€Icariin
CAS :Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Formule :C33H40O15Degré de pureté :97.82% - 98.49%Couleur et forme :SolidMasse moléculaire :676.66Irinotecan Hydrochloride
CAS :Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.Formule :C33H39ClN4O6Degré de pureté :98% - 99.94%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :623.14Ref: TM-T0486L
10mg35,00€25mg52,00€50mg69,00€100mg95,00€200mg136,00€500mg268,00€1mL*10mM (DMSO)74,00€Nicardipine hydrochloride
CAS :Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.Formule :C26H30ClN3O6Degré de pureté :99.58% - 99.89%Couleur et forme :Yellow SolidMasse moléculaire :515.99Verteporfin
CAS :Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.Formule :C41H42N4O8Degré de pureté :95.37% - 99.82%Couleur et forme :Dark Green To Black SolidMasse moléculaire :718.79Ref: TM-T3112
1mg40,00€2mg51,00€5mg85,00€10mg115,00€25mg225,00€50mg365,00€100mg462,00€1mL*10mM (DMSO)120,00€BL-918
CAS :BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.Formule :C23H15F8N3OSDegré de pureté :99.11% - 99.40%Couleur et forme :SolidMasse moléculaire :533.44Ref: TM-T8322
1mg49,00€2mg70,00€5mg104,00€10mg156,00€25mg284,00€50mg455,00€100mg747,00€500mg1.501,00€1mL*10mM (DMSO)127,00€4E1rcat
CAS :4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.Formule :C28H18N2O6Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :478.45Atezolizumab
CAS :Atezolizumab is an antibody inhibitor, a humanized monoclonal antibody, IgG1, which targets PD-L1. Atezolizumab has antitumor effect. Cost-effective and quality-assured.Degré de pureté :95.10% - 99.3% （SEC-HPLC）Couleur et forme :LiquidMasse moléculaire :145 kDaTamibarotene
CAS :Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplasticFormule :C22H25NO3Degré de pureté :97.22% - 98.2%Couleur et forme :Crystalline SolidMasse moléculaire :351.44Ref: TM-T6694
1g369,00€10mg47,00€25mg64,00€50mg79,00€100mg97,00€200mg153,00€500mg249,00€1mL*10mM (DMSO)47,00€PF-06454589
CAS :PF-06454589 is a potent inhibitor of LRRK2.Formule :C14H16N6ODegré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :284.32Ref: TM-T7729
2mg35,00€5mg50,00€10mg80,00€25mg135,00€50mg197,00€100mg306,00€200mg442,00€1mL*10mM (DMSO)55,00€Deguelin
CAS :Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.Formule :C23H22O6Degré de pureté :96.39% - 99.29%Couleur et forme :SolidMasse moléculaire :394.42Idarubicin hydrochloride
CAS :Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).Formule :C26H27NO9·HClDegré de pureté :100% - 99.93%Couleur et forme :SolidMasse moléculaire :533.95Ancitabine hydrochloride
CAS :Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity.Formule :C9H12ClN3O4Degré de pureté :99.02% - 99.37%Couleur et forme :White SolidMasse moléculaire :261.66SMER28
CAS :SMER28 triggers autophagy in cells without mTOR, blocking amyloid beta buildup.Formule :C11H10BrN3Degré de pureté :99.94% - 99.97%Couleur et forme :SolidMasse moléculaire :264.12Ref: TM-T3155
5mg51,00€10mg73,00€25mg127,00€50mg235,00€100mg452,00€200mg660,00€500mg1.035,00€1mL*10mM (DMSO)51,00€Sapanisertib
CAS :Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.Formule :C15H15N7ODegré de pureté :100% - 99.67%Couleur et forme :SolidMasse moléculaire :309.33Ref: TM-T1838
1mg40,00€2mg51,00€5mg85,00€10mg96,00€25mg160,00€50mg235,00€100mg350,00€500mg838,00€1mL*10mM (DMSO)88,00€DPN
CAS :DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .Formule :C15H13NO2Degré de pureté :99.01%Couleur et forme :Off-White SolidMasse moléculaire :239.27Memantine hydrochloride
CAS :Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects.Formule :C12H22ClNDegré de pureté :99.56% - 99.96%Couleur et forme :Crystalline SolidMasse moléculaire :215.763Britannin
CAS :Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.Formule :C19H26O7Degré de pureté :98% - 98.53%Couleur et forme :SolidMasse moléculaire :366.41Oxyphenisatin acetate
CAS :Oxyphenisatin acetate inhibits the growth of the breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468.Formule :C24H19NO5Degré de pureté :98% - 98.62%Couleur et forme :SolidMasse moléculaire :401.41Baicalin
CAS :Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFormule :C21H18O11Degré de pureté :90.08% - 99.25%Couleur et forme :Yellow PowderMasse moléculaire :446.36Hoechst 33342
CAS :Hoechst 33342: a benzimidazole dye, DNA stain for AT-rich regions, cell-permeable, quantifies DNA in live cells.Formule :C27H28N6ODegré de pureté :98.45% - 99.57%Couleur et forme :Yellow-Green PowderMasse moléculaire :452.55Retinoic acid
CAS :Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.Formule :C20H28O2Degré de pureté :97.21% - 99.6%Couleur et forme :Yellow-Orange PowderMasse moléculaire :300.44Crenolanib
CAS :Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).Formule :C26H29N5O2Degré de pureté :97.45% - 99.28%Couleur et forme :SolidMasse moléculaire :443.54SBI-0206965
CAS :SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.Formule :C21H21BrN4O5Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :489.32DAPT
CAS :DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.Formule :C23H26F2N2O4Degré de pureté :98.06% - 99.81%Couleur et forme :White SolidMasse moléculaire :432.46Ref: TM-T6202
5mg58,00€10mg88,00€25mg165,00€50mg279,00€100mg414,00€200mg517,00€500mg835,00€1mL*10mM (DMSO)59,00€Omeprazole Sodium
CAS :Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Formule :C17H18N3NaO3SDegré de pureté :99.57%Couleur et forme :Clear In WaterMasse moléculaire :367.4SR-3677
CAS :SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).Formule :C22H24N4O4Degré de pureté :98.46%Couleur et forme :SolidMasse moléculaire :408.45H-89 dihydrochloride
CAS :H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).Formule :C20H20BrN3O2S·2HClDegré de pureté :100% - 99.40%Couleur et forme :SolidMasse moléculaire :519.28Ref: TM-T6250
5mg39,00€10mg58,00€25mg106,00€50mg202,00€100mg344,00€200mg512,00€500mg815,00€1mL*10mM (DMSO)52,00€Meloxicam
CAS :Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.Formule :C14H13N3O4S2Degré de pureté :97.09% - 99.60%Couleur et forme :Light Yellow SolidMasse moléculaire :351.4Autogramin-2
CAS :Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by eitherFormule :C21H27N3O4SDegré de pureté :96.25%Couleur et forme :SolidMasse moléculaire :417.52AS-605240
CAS :AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).Formule :C12H7N3O2SDegré de pureté :97% - 99.91%Couleur et forme :SolidMasse moléculaire :257.27PTC-209
CAS :PTC-209 is a potent and selective BMI-1 inhibitor.Formule :C17H13Br2N5OSDegré de pureté :99.43% - 99.60%Couleur et forme :SolidMasse moléculaire :495.19Curcumin
CAS :Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.Formule :C21H20O6Degré de pureté :95% - 98.98%Couleur et forme :Orange-Yellow Crystal Powder; Gives Brownish-Red Color With Alkali; Light-Yellow Color With Acids Physical Description Orange-Yellow Needles (Ntp 1992)Masse moléculaire :368.3799JH-II-127
CAS :JH-II-127 is an oral LRRK2 inhibitor with IC50s: 6.6 nM (WT), 2.2 nM (G2019S), 47.7 nM (A2016T).Formule :C19H21ClN6O3Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :416.86Pantoprazole
CAS :Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFormule :C16H15F2N3O4SDegré de pureté :99.28% - 99.63%Couleur et forme :Almost White SolidMasse moléculaire :383.37MAO-B-IN-26
CAS :MAO-B-IN-26 (Compound IC9) serves as both a MAO-B and acetylcholinesterase inhibitor.Formule :C17H12BrNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :326.19Tea polyphenol
CAS :Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea.Formule :C17H19N3ODegré de pureté :98%Couleur et forme :Yelloish Green Free Flowing PowderMasse moléculaire :281.36Venetoclax
CAS :Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48/245 nM).Formule :C45H50ClN7O7SDegré de pureté :98% - 99.96%Couleur et forme :SolidMasse moléculaire :868.44LY2109761
CAS :LY2109761: a TGF-β dual inhibitor, Ki=38 nM (TβRI) & 300 nM (TβRII), hinders Smad2 phosphorylation.Formule :C26H27N5O2Degré de pureté :97% - 99.83%Couleur et forme :SolidMasse moléculaire :441.52Ref: TM-T2123
2mg47,00€5mg70,00€10mg111,00€25mg188,00€50mg335,00€100mg507,00€200mg730,00€1mL*10mM (DMSO)77,00€Chelerythrine
CAS :1.Formule :C21H18NO4Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :348.37Regorafenib monohydrate
CAS :Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFormule :C21H17ClF4N4O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :500.83Ref: TM-T1792L
5mg35,00€10mg48,00€25mg69,00€50mg88,00€100mg140,00€200mg207,00€500mg348,00€1mL*10mM (DMSO)58,00€Thalidomide
CAS :Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.Formule :C13H10N2O4Degré de pureté :98.88% - 99.88%Couleur et forme :White SolidMasse moléculaire :258.23Taxifolin
CAS :Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.Formule :C15H12O7Degré de pureté :94.91% - 98.9%Couleur et forme :Yellowish PowderMasse moléculaire :304.25Beclin1-ATG14L interaction inhibitor 1
CAS :Beclin1-ATG14L Interaction Inhibitor 1 (COM 19) is a selective inhibitor targeting the specific interaction between Beclin1 and ATG14L.Formule :C23H24N4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.53Matrine
CAS :Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.Formule :C15H24N2ODegré de pureté :100% - 97.16%Couleur et forme :SolidMasse moléculaire :248.36SLW131
CAS :SLW131 (Compound 10) is a CCR7 antagonist with strong affinity, showing a Ki of 9.85 nM. It inhibits CCL19-induced Go protein activation with an IC50 of 29.4 μM and β-arrestin2 recruitment with an IC50 of 6.0 μM. SLW131 also suppresses CCL19-induced morphological changes in primary BMDC cells and CCR7-mediated migration of mouse CD4+ T cells.Formule :C21H27N5O5SCouleur et forme :SolidMasse moléculaire :461.535Alginic acid
CAS :Alginic acid, a polysaccharide from brown seaweed, has anti-anaphylactic and anti-inflammatory properties and is used in food industry.Formule :C14H22O13Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :398.317GSK-690693
CAS :GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.Formule :C21H27N7O3Degré de pureté :100% - 98.78%Couleur et forme :SolidMasse moléculaire :425.48Brivanib
CAS :Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold againstFormule :C19H19FN4O3Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :370.38Ref: TM-T6036
1mg47,00€5mg88,00€10mg144,00€25mg259,00€50mg375,00€100mg560,00€200mg815,00€1mL*10mM (DMSO)97,00€SGI-1776
CAS :SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.Formule :C20H22F3N5ODegré de pureté :100% - 99.84%Couleur et forme :SolidMasse moléculaire :405.42Carboplatin
CAS :Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.Formule :C6H12N2O4PtDegré de pureté :98% - 99.72%Couleur et forme :White Crystalline PowderMasse moléculaire :371.25Licochalcone A
CAS :Licochalcone A is a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch with obvious anti-cancer effects.Formule :C21H22O4Degré de pureté :98.11% - 98.96%Couleur et forme :White Crystalline PowderMasse moléculaire :338.4PD 169316
CAS :PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.Formule :C20H13FN4O2Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :360.34URB-597
CAS :URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.Formule :C20H22N2O3Degré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :338.4LRRK2-IN-10
CAS :LRRK2-IN-10 (compound 34) is a potent, mutation-selective, brain-penetrant inhibitor targeting G2019S-LRRK2 kinase with IC50 values of 11 nM for G2019S-LRRK2Formule :C20H15N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :341.37LC3-mHTT-IN-AN1
CAS :LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B.Formule :C15H9Br2NO3Degré de pureté :97.26%Couleur et forme :SolidMasse moléculaire :411.04Spautin-1
CAS :Spautin-1 is an autophagy inhibitor that can suppress the deubiquitination activity of ubiquitin-specific peptidase USP10 and USP13. Cost-effective and quality-assured.Formule :C15H11F2N3Degré de pureté :97.69% - 98.99%Couleur et forme :SolidMasse moléculaire :271.26Nesolicaftor
CAS :Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.Formule :C18H18N4O4Degré de pureté :98.64%Couleur et forme :SolidMasse moléculaire :354.36Ref: TM-T16681
1mg96,00€5mg215,00€10mg378,00€25mg650,00€50mg927,00€100mg1.254,00€1mL*10mM (DMSO)236,00€2-Methoxyestradiol
CAS :2-ME2, an estradiol derivative, hinders angiogenesis and tumor growth, causes cell apoptosis, and stops mitosis.Formule :C19H26O3Degré de pureté :98% - 99.95%Couleur et forme :Off-White SolidMasse moléculaire :302.41Schisandrin
CAS :Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.Formule :C24H32O7Degré de pureté :98.97% - 99.32%Couleur et forme :White PowderMasse moléculaire :432.51
