SGLT
Les co-transporteurs sodium-glucose (SGLT) sont des protéines membranaires qui facilitent la réabsorption du glucose dans les reins en couplant le transport du glucose avec des ions sodium. Les inhibiteurs des SGLT constituent une classe importante de médicaments utilisés dans le traitement du diabète de type 2, car ils aident à réduire les niveaux de glucose dans le sang en empêchant la réabsorption du glucose dans les tubules rénaux. Ces inhibiteurs sont également étudiés pour leurs bénéfices potentiels dans la protection cardiovasculaire et rénale. Chez CymitQuimica, nous offrons une gamme de modulateurs SGLT de haute qualité pour soutenir vos recherches en diabète, physiologie rénale et troubles métaboliques.
Produits appartenant à la catégorie "SGLT"
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29 produits dans cette catégorie.
Ertugliflozin L-pyroglutamic acid
CAS :Ertugliflozin is a potent oral hSGLT2 inhibitor (IC50: 0.877 nM) for type 2 diabetes treatment studies.Formule :C27H32ClNO10Degré de pureté :98.71% - 99.84%Couleur et forme :SolidMasse moléculaire :566Ref: TM-T15244
5mg47,00€10mg60,00€25mg89,00€50mg96,00€100mg140,00€200mg198,00€500mg340,00€1mL*10mM (DMSO)52,00€Licogliflozin
CAS :Licogliflozin (LIK066) is an inhibitor of sodium-glucose cotransporter (SGLT1 and SGLT2).Formule :C23H28O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.46Bexagliflozin
CAS :Bexagliflozin (EGT1442) is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 2 nM for human SGLT2.Formule :C24H29ClO7Degré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :464.94Ref: TM-T7217
1mg71,00€2mg90,00€5mg136,00€10mg197,00€25mg393,00€50mg582,00€100mg830,00€1mL*10mM (DMSO)144,00€Dapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS :Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-Formule :C24H35ClO9Degré de pureté :99.88% - 99.94%Couleur et forme :SolidMasse moléculaire :502.98KGA-2727
CAS :KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.Formule :C26H40N4O8Degré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :536.62Ref: TM-T15656
1mg120,00€5mg274,00€10mg454,00€25mg750,00€50mg1.026,00€100mg1.406,00€200mg1.890,00€1mL*10mM (DMSO)323,00€T-1095
CAS :T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).Formule :C26H28O11Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :516.49Ref: TM-T9590
1mg52,00€2mg74,00€5mg96,00€10mg137,00€25mg217,00€50mg391,00€100mg560,00€1mL*10mM (DMSO)134,00€Sergliflozin etabonate
CAS :Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity.Formule :C23H28O9Degré de pureté :95.59%Couleur et forme :SolidMasse moléculaire :448.46Ref: TM-T28757
1mg185,00€2mg279,00€5mg425,00€10mg625,00€25mg938,00€50mg1.311,00€100mg1.795,00€1mL*10mM (DMSO)490,00€O-Desethyl Dapagliflozin
CAS :O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.Formule :C19H21ClO6Degré de pureté :97.09%Couleur et forme :SolidMasse moléculaire :380.82Ref: TM-T67849
1mg57,00€5mg120,00€10mg187,00€25mg321,00€50mg470,00€100mg683,00€1mL*10mM (DMSO)135,00€Tofogliflozin (hydrate)
CAS :Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2(Ki of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2).Formule :C22H28O7Degré de pureté :97.02% - 98.78%Couleur et forme :SolidMasse moléculaire :404.45Ref: TM-T5016
1mg46,00€2mg59,00€5mg87,00€10mg140,00€25mg259,00€50mg467,00€100mg653,00€200mg927,00€500mg1.359,00€1mL*10mM (DMSO)96,00€Canagliflozin hemihydrate
CAS :Canagliflozin hemihydrate (TA 7284) treats type 2 diabetes by blocking SGLT2, leading to glucose excretion in urine.Formule :C48H52F2O11S2Degré de pureté :99.42% - 99.96%Couleur et forme :SolidMasse moléculaire :907.05SGL5213
CAS :SGL5213 is a potent oral SGLT1 inhibitor (IC50: 29 nM) with potential for treating type 2 diabetes.Formule :C37H55N3O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :669.85Phlorizin
CAS :Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .Formule :C21H24O10Degré de pureté :99.58% - 99.76%Couleur et forme :Solid CrystallineMasse moléculaire :436.41Sergliflozin A
CAS :Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia.Formule :C20H24O7Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :376.4Canagliflozin
CAS :Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor. Canagliflozin is used to treat type II diabetes mellitus. Cost-effective and quality-assured.Formule :C24H25FO5SDegré de pureté :100% - 99.76%Couleur et forme :SolidMasse moléculaire :444.52Mizagliflozin
CAS :Mizagliflozin is an orally active, selective SGLT1 inhibitor with a Ki value of 27 nM for human SGLT1.Cost-effective and quality-assured.Formule :C28H44N4O8Degré de pureté :98.32% - 98.66%Couleur et forme :SolidMasse moléculaire :564.67Ref: TM-T16083
1mg81,00€2mg105,00€5mg163,00€10mg274,00€25mg542,00€50mg778,00€100mg1.074,00€1mL*10mM (DMSO)212,00€SGLT inhibitor-1
CAS :SGLT inhibitor-1 is a potentsodium glucose co-transporter proteins (SGLTs) dual inhibitor(hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively).Formule :C24H27FO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :462.46Trilobatin
CAS :Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFormule :C21H24O10Degré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :436.41Ref: TM-T2S0731
1mg64,00€5mg124,00€10mg165,00€25mg323,00€50mg487,00€100mg710,00€1mL*10mM (DMSO)137,00€Sotagliflozin
CAS :Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potentialFormule :C21H25ClO5SDegré de pureté :99% - 99.78%Couleur et forme :SolidMasse moléculaire :424.94Ref: TM-T3547
1mg46,00€2mg57,00€5mg87,00€10mg131,00€25mg248,00€50mg378,00€100mg560,00€500mg1.198,00€1mL*10mM (DMSO)88,00€Enavogliflozin
CAS :Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.Formule :C24H27ClO6Degré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :446.92Ref: TM-T38843
1mg156,00€5mg378,00€10mg590,00€25mg1.026,00€50mg1.406,00€100mg1.863,00€1mL*10mM (DMSO)415,00€Ipragliflozin
CAS :Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.Formule :C21H21FO5SDegré de pureté :99.38% - 99.70%Couleur et forme :SolidMasse moléculaire :404.45Ertugliflozin
CAS :PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).Formule :C22H25ClO7Degré de pureté :99.89% - 99.96%Couleur et forme :SolidMasse moléculaire :436.88Dapagliflozin
CAS :Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.Formule :C21H25ClO6Degré de pureté :99.5% - 99.74%Couleur et forme :SolidMasse moléculaire :408.87Velagliflozin
CAS :Velagliflozin is an orally available inhibitor of sodium-glucose cotransporter 2.Formule :C23H25NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :395.45Leachianone A
CAS :Leachianone A (Isokurarinone) is a potential antitoxic agent, it shows inhibitory effects on cadmium- Induced cytotoxicity.Formule :C26H30O6Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :438.51IRAK inhibitor 4 trans
IRAK inhibitor 4 targets and blocks IRAK4 activity; refers to its trans molecular configuration.Formule :C33H35F3N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :620.66Phloretin
CAS :Phloretin (NSC-407292) inhibits eukaryotic urea transporters, has antioxidative properties, and can induce cancer cell apoptosis. Found in apples and apricots.Formule :C15H14O5Degré de pureté :100% - 99.76%Couleur et forme :SolidMasse moléculaire :274.27Remogliflozin etabonate
CAS :Remogliflozin etabonate is a prodrug SGLT2 inhibitor; Ki for hSGLT2: 1.95μM, rSGLT2: 2.14μM, rSGLT1: 8.57μM, hSGLT1: 43.1μM.Formule :C26H38N2O9Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :522.59Ref: TM-T34286
2mg35,00€5mg52,00€10mg96,00€25mg164,00€50mg245,00€100mg340,00€200mg472,00€1mL*10mM (DMSO)62,00€Empagliflozin
CAS :Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6.Formule :C23H27ClO7Degré de pureté :98% - 99.89%Couleur et forme :SolidMasse moléculaire :450.91Ref: TM-T1766
1g278,00€5mg47,00€10mg60,00€50mg79,00€100mg96,00€200mg144,00€500mg188,00€1mL*10mM (DMSO)50,00€HSK0935
CAS :HSK0935 is a highly selective and orally available SGLT2 inhibitor (IC50: 1.3 nM). It has antihyperglycemic activities.Formule :C22H25ClO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.88
