Protéase du VIH
Les inhibiteurs de la protéase du VIH sont une classe de médicaments antirétroviraux qui ciblent spécifiquement l'enzyme protéase du virus de l'immunodéficience humaine (VIH). En inhibant cette enzyme, ces composés empêchent le virus de transformer ses polyprotéines en protéines matures et fonctionnelles, bloquant ainsi la production de nouveaux virions infectieux. Les inhibiteurs de la protéase du VIH constituent une pierre angulaire de la thérapie antirétrovirale hautement active (HAART) utilisée pour gérer le VIH/SIDA. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de la protéase du VIH pour soutenir votre recherche sur le traitement du VIH, la résistance médicamenteuse et la virologie.
Produits appartenant à la catégorie "Protéase du VIH"
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(S)-BI-1001
CAS :(S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM).Formule :C19H15BrClNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.68Censavudine
CAS :Censavudine (OBP-601) is an HIV-1/2 treatment and prevention drug, a reverse transcriptase inhibitor with EC50 of 30-890 nM.Formule :C12H12N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :248.23Salmeterol Xinafoate
CAS :Salmeterol Xinafoate (GR 33343X xinafoate) is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma.Formule :C36H45NO7Degré de pureté :98% - 98.24%Couleur et forme :White SolidMasse moléculaire :603.75Doravirine
CAS :Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.Formule :C17H11ClF3N5O3Degré de pureté :99.65% - 99.79%Couleur et forme :SolidMasse moléculaire :425.75Ref: TM-T3632
1mg49,00€2mg69,00€5mg97,00€10mg170,00€25mg335,00€50mg520,00€100mg750,00€500mg1.549,00€1mL*10mM (DMSO)131,00€Atevirdine
CAS :Atevirdine is an HIV-1 reverse transcriptase inhibitor with antiviral activity for the study of the AIDS dementia complex (ADC).Formule :C21H25N5O2Degré de pureté :98.75%Couleur et forme :SolidMasse moléculaire :379.46Opaviraline
CAS :Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.Formule :C14H17FN2O3Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :280.29Ref: TM-T28255
1mg378,00€5mg922,00€10mg1.225,00€25mg1.853,00€50mg2.490,00€100mg3.353,00€1mL*10mM (DMSO)823,00€Lamivudine
CAS :Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring.Formule :C8H11N3O3SDegré de pureté :100% - 99.56%Couleur et forme :White Crystalline PowderMasse moléculaire :229.26Pentosan Polysulfate Sodium (W/W 43%)
CAS :Pentosan Polysulfate Sodium: anti-HIV, anti-inflammatory, aids cartilage, treats interstitial cystitis.Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/ALenacapavir
CAS :Lenacapavir (GS-6207) is the first HIV-1 capsid inhibitor approved by the U.S. Food and Drug Administration, the European Medicines Agency, and Health Canada for the treatment of MDR HIV-1 infection.Cost-effective and quality-assured.Formule :C39H32ClF10N7O5S2Degré de pureté :100.00% - 99.61%Couleur et forme :SolidMasse moléculaire :968.28Gamibetal
CAS :Gamibetal (4-Amino-3-hydroxybutyric Acid) is used as a chiral reagent in the synthesis of antiepileptic and hypotensive drug GABOB and analogues.Formule :C4H9NO3Degré de pureté :99.96%Couleur et forme :White Crystalline PowderMasse moléculaire :119.12Bryostatin 1
CAS :Bryostatin 1, a marine macrolide, permeates CNS and modulates PKC, with strong affinity for Munc13-1 (Ki: 8.07 nM and 0.45 nM).Formule :C47H68O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :905.03Amylmetacresol
CAS :Amylmetacresol treats sore throat, pharyngitis, tonsillitis, laryngitis, influenza A, and SARS-CoV.Formule :C12H18ODegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :178.27AzddMeC
CAS :AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infectionFormule :C10H14N6O3Degré de pureté :97.65% - 99.62%Couleur et forme :SolidMasse moléculaire :266.26Emtricitabine
CAS :Emtricitabine is a nucleoside reverse transcriptase inhibitor with anti-human immunodeficiency virus (HIV) and hepatitis B virus activity.Cost-effective and quality-assured.Formule :C8H10FN3O3SDegré de pureté :100% - 99.78%Couleur et forme :White PowderMasse moléculaire :247.25Clathrin-IN-1
CAS :Pitstop 2 inhibits clathrin-mediated endocytosis, targeting clathrin's terminal domain, with potential in cancer research.Formule :C20H13BrN2O3S2Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :473.36Ref: TM-T9063
1mg52,00€2mg77,00€5mg96,00€10mg149,00€25mg259,00€50mg378,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)111,00€Des(benzylpyridyl) Atazanavi
CAS :The N-dealkylated metabolite (M1) of Atazanavir, a HIV protease inhibitor.Formule :C26H43N5O7Degré de pureté :98% - 99.75%Couleur et forme :SolidMasse moléculaire :537.65Elvitegravir
CAS :Elvitegravir (JTK-303) is an HIV integrase inhibitor and CYP2C9 inducer.Formule :C23H23ClFNO5Degré de pureté :98.35% - 99.73%Couleur et forme :SolidMasse moléculaire :447.88Saquinavir
CAS :Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.Formule :C38H50N6O5Degré de pureté :100% - 99.50%Couleur et forme :SolidMasse moléculaire :670.84Cytochalasin A
CAS :Cytochalasin A, a cell-penetrating fungal toxin, blocks HIV-1 protease (IC50 = 3 μM) and hinders actin and microtubule assembly. It's an antibiotic.Formule :C29H35NO5Degré de pureté :98%Couleur et forme :White Crystalline PowderMasse moléculaire :477.59Cosalane
CAS :Cosalane (NSC 658586) is an HIV replication inhibitor and an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice.Formule :C45H60Cl2O6Degré de pureté :100% - 98.82%Couleur et forme :SolidMasse moléculaire :767.86Fosamprenavir Calcium Salt
CAS :Fosamprenavir Calcium Salt (GW433908G) (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility.Formule :C25H34CaN3O9PSDegré de pureté :99.59%Couleur et forme :White Microcrystalline NeedlesMasse moléculaire :623.67Isoescin IA
CAS :Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. It has anti-HIV-1 protease activity.Formule :C55H86O24Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :1131.26(Rac)-Telinavir
CAS :N1 compound with anti-HIV activity; contains dimethyl, phenyl, quinoline groups.Formule :C33H44N6O5Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :604.74gp120-α4β7 binding inhibitor 11
CAS :gp120-α4β7 binding inhibitor 11 is an anti-HIV agent.Formule :C26H27N3O2Degré de pureté :97.61%Couleur et forme :SolidMasse moléculaire :413.51Ref: TM-T67737
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€200mg1.444,00€1mL*10mM (DMSO)278,00€Tenofovir alafenamide
CAS :Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.Formule :C21H29N6O5PDegré de pureté :99% - 99.81%Couleur et forme :SolidMasse moléculaire :476.47Terameprocol
CAS :Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.Formule :C22H30O4Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :358.473-Deazaadenosine
CAS :3-Deazaadenosine, an inhibitor of S-adenosylhomocysteine hydrolase with a Ki of 3.9 μM, exhibits anti-inflammatory, anti-proliferative, and anti-HIV activity.Formule :C11H14N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :266.25CA inhibitor 1
CAS :CA inhibitor 1 (GS-6207 analog) is a potent inhibitor of the HIV capsid.Formule :C41H36ClF8N7O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :958.34PF-3450074
CAS :PF-3450074 (PF-74) is a specific HIV-1 inhibitor, blocking viral replication and uncoating at submicromolar EC50=8-640 nM.Formule :C27H27N3O2Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :425.52Nelfinavir Mesylate
CAS :Nelfinavir Mesylate (Viracept) is an effective HIV protease inhibitor (Ki: 2 nM).Formule :C33H49N3O7S2Degré de pureté :95.81% - 98.27%Couleur et forme :A White Or Almost White PowderMasse moléculaire :663.89HIV-1 protease-IN-11
CAS :HIV-1 protease-IN-11 (compound 34a), an HIV-1 protease inhibitor, demonstrates potent inhibition with an IC50 of 0.41 nM and maintains substantial efficacyFormule :C26H37N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :503.65CCR5 antagonist 1
CAS :CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.Formule :C39H46ClF2N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :738.33CDK9-IN-1
CAS :CDK9-IN-1 is a selective and potent CDK9 inhibitor with antiviral activity used in the study of PRRSV infections.Formule :C26H21N5O4SDegré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :499.54HIV-1 integrase inhibitor 8
CAS :HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].Formule :C21H24O2Degré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :308.41Tenofovir diphosphate TEA
CAS :Tenofovir diphosphate TEA (TFV-DP TEA) is an ATP-competitive DNA polymerase inhibitor that inhibits HIV-1 reverse transcriptase that\has anti-HIV/HBV potential.Formule :C9H16N5O10P3·C6H15NDegré de pureté :93.45% - 98.51%Couleur et forme :SolidMasse moléculaire :548.36PMEDAP
CAS :PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiencyFormule :C8H13N6O4PDegré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :288.2Reverse transcriptase-IN-1
CAS :Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7Formule :C25H17N7O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :447.45Ref: TM-T12715
1mg64,00€5mg131,00€10mg183,00€25mg311,00€50mg449,00€100mg615,00€200mg833,00€1mL*10mM (DMSO)143,00€PNU-103017
CAS :PNU-103017 is an inhibitor of HIV protease.Formule :C28H28N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.6Delavirdine mesylate
CAS :Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).Formule :C23H32N6O6S2Degré de pureté :99.99%Couleur et forme :Light Brown SolidMasse moléculaire :552.67Rilpivirine
CAS :Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatmentFormule :C22H18N6Degré de pureté :97.22% - 98.83%Couleur et forme :SolidMasse moléculaire :366.42Ref: TM-T2330
2mg38,00€5mg55,00€10mg88,00€25mg145,00€50mg243,00€100mg359,00€500mg842,00€1mL*10mM (DMSO)80,00€Darunavir Ethanolate
CAS :Darunavir Ethanolate (UIC 94017) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.Formule :C29H43N3O8SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :593.74Ref: TM-T3335
5mg37,00€10mg52,00€25mg80,00€50mg111,00€100mg165,00€200mg236,00€500mg399,00€1mL*10mM (DMSO)48,00€Stercobilin hydrochloride (mixture of isomers)
CAS :Stercobilin hydrochloride (mixture of isomers) is a bile pigment metabolized by intestinal bacteria and also acts as an inhibitor of HIV protease (HIVProtease) with a Ki of 4 μM. This compound can induce pro-inflammatory activity in mouse macrophage RAW264 cells, including the production of TNF-α and IL-1β. Stercobilin hydrochloride (mixture of isomers) is utilized in research on inflammation and viral infections.Formule :C33H47ClN4O6Couleur et forme :SolidMasse moléculaire :631.20HIV-IN-6
CAS :HIV-IN-6, an anti-HIV agent, blocks replication by targeting SFKs like Hck involved with Nef protein.Formule :C20H16N4O3SDegré de pureté :97.12%Couleur et forme :SolidMasse moléculaire :392.43Oxindole
CAS :Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.Formule :C8H7NODegré de pureté :99.34%Couleur et forme :Off-White Crystalline PowderMasse moléculaire :133.15Rolipram
CAS :Rolipram (SB 95952) is a phosphodiesterase 4 inhibitor with antidepressant properties.Formule :C16H21NO3Degré de pureté :99.22% - 99.26%Couleur et forme :SolidMasse moléculaire :275.34Rosamultin
CAS :Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity.Formule :C36H58O10Degré de pureté :98% - 99.83%Couleur et forme :SolidMasse moléculaire :650.84Cabotegravir
CAS :Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (Formule :C19H17F2N3O5Degré de pureté :98.55% - 99.92%Couleur et forme :SolidMasse moléculaire :405.35Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2
CAS :Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate for the HIV-1 protease, facilitating the assessment of enzyme activity [1].Formule :C40H66N12O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :891.03L 756423
CAS :L756423 is a potent, selective HIV protease inhibitor (Ki=0.049 nM), effective against HIV spread in MT25 lymphocytes at 0.1-0.5 nM, useful for AIDS research.Formule :C39H48N4O5Degré de pureté :100% - 100%Couleur et forme :SolidMasse moléculaire :652.82Mavorixafor trihydrochloride
CAS :Mavorixafor trihydrochloride blocks CXCR4 (IC50: 13 nM) and suppresses T-tropic HIV-1 replication (IC50: 1-9 nM). It's orally active.Formule :C21H30Cl3N5Degré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :458.86NBD-557
CAS :NBD-557 is a potentially HIV-1 inhibitor.Formule :C17H24BrN3O2Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :382.3Ref: TM-T7382
1mg48,00€5mg97,00€10mg156,00€25mg301,00€50mg437,00€100mg620,00€200mg843,00€1mL*10mM (DMSO)105,00€Bellidifolin
CAS :Bellidoferin: anti-oxidant, protects liver, fights inflammation/tumors, aids nerve injury, blocks MAO A, may improve type-2 diabetes, antifungal.Formule :C14H10O6Degré de pureté :99.79% - 99.81%Couleur et forme :SolidMasse moléculaire :274.23Ref: TM-T3822
1mg96,00€5mg225,00€10mg323,00€25mg537,00€50mg752,00€100mg1.035,00€1mL*10mM (DMSO)202,00€Talviraline
CAS :Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in aFormule :C15H20N2O3S2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :340.46Lopinavir
CAS :Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation.Formule :C37H48N4O5Degré de pureté :98% - 99.62%Couleur et forme :White Crystalline SolidMasse moléculaire :628.83-Deazaadenosine hydrochloride
CAS :3-Deazaadenosine HCl blocks SAH hydrolase (Ki: 3.9 μM), with anti-inflammatory, anti-proliferative, and anti-HIV effects.Formule :C11H15ClN4O4Degré de pureté :98.48%Couleur et forme :SolidMasse moléculaire :302.71Ref: TM-T10111
1mg126,00€5mg216,00€10mg374,00€25mg620,00€50mg868,00€100mg1.169,00€1mL*10mM (DMSO)149,00€Maraviroc
CAS :Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s-MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.Formule :C29H41F2N5ODegré de pureté :100% - 99.55%Couleur et forme :Brown SolidMasse moléculaire :513.67Ref: TM-T6016
5mg51,00€10mg95,00€25mg160,00€50mg273,00€100mg492,00€200mg633,00€500mg998,00€1mL*10mM (DMSO)59,00€HIV-1 inhibitor-53
CAS :HIV-1 Inhibitor-53 targets HIV-1 protease (IC50: 1.93 nM) and reverse transcriptase (IC50: 2.35 μM), aiding AIDS research.Formule :C30H34N2O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :582.66Raltegravir potassium
CAS :Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.Formule :C20H20FN6O5·KDegré de pureté :98% - 99.55%Couleur et forme :Off-White SolidMasse moléculaire :482.51Nevirapine
CAS :Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor.Formule :C15H14N4ODegré de pureté :99.58% - 99.59%Couleur et forme :White Or Off-White Crystalline PowderMasse moléculaire :266.3Ro24-7429
CAS :Ro24-7429: oral HIV-1 Tat antagonist, RUNX1 inhibitor with anti-HIV, antifibrotic, and anti-inflammatory properties.Formule :C14H13ClN4Degré de pureté :99.29% - 99.85%Couleur et forme :SolidMasse moléculaire :272.73Ref: TM-T28578
1mg92,00€5mg187,00€10mg298,00€25mg507,00€50mg730,00€100mg1.026,00€500mg2.877,00€1mL*10mM (DMSO)215,00€HIV-1 protease-IN-7
CAS :HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].Formule :C68H104N10O12SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1285.68Dolutegravir intermediate-1
CAS :Dolutegravir intermediate-1 is a synthetic precursor for HIV-1 treatment from patent WO 2016125192 A2.Formule :C13H17NO8Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :315.28AMD 3465
CAS :AMD 3465 (GENZ-644494) blocks CXCR4, hinders X4 HIV replication (IC50: 1-10 nM), ineffective against R5 viruses, IC50: 0.75 nM (12G5 mAb), 18 nM (CXCL12AF647).Formule :C24H38N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :410.60Didanosine
CAS :Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).Formule :C10H12N4O3Degré de pureté :99.64%Couleur et forme :White Crystalline PowderMasse moléculaire :236.23Obefazimod
CAS :Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).Formule :C16H10ClF3N2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :338.71Ref: TM-T8311
2mg39,00€5mg62,00€10mg87,00€25mg187,00€50mg301,00€100mg437,00€200mg617,00€1mL*10mM (DMSO)65,00€Trovirdine
CAS :Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor.Formule :C13H13BrN4SDegré de pureté :98.12% - 98.50%Couleur et forme :SolidMasse moléculaire :337.24HIV-1 inhibitor-54
CAS :HIV-1 inhibitor-54: potent anti-HIV (EC50: 32 nM), targets WT HIV-1 IIIB in MT-4 cells for infection research.Formule :C27H30N6O4SDegré de pureté :97.61% - 98.61%Couleur et forme :SoildMasse moléculaire :534.63Pepstatin
CAS :Pepstatin (Pepsin Inhibitor S 735A) is a specific and orally aspartate protease inhibitor that also inhibits HIV protease activity. Cost effective and quality assured.Formule :C34H63N5O9Degré de pureté :96.74% - 99.94%Couleur et forme :SolidMasse moléculaire :685.89
