Composés polycycliques

Anhydrobyankangelicin is a coumarin derivative, which is a specialized type of organic compound commonly found in the plant family Apiaceae. This compound is biosynthetically sourced from the roots of plants such as Angelica species, where it is observed in varying concentrations. Anhydrobyankangelicin operates through interactions with several biological pathways, including modulating calcium channels and inhibiting certain enzymes involved in oxidative stress. This mechanism of action contributes to its efficacy in providing neuroprotective effects. In scientific contexts, Anhydrobyankangelicin is primarily investigated for its potential therapeutic applications in neurodegenerative diseases. Its ability to influence multiple pathways at a cellular level makes it a compound of interest for mitigating cellular damage and reducing inflammation in neurological tissues. Current research explores its usage in experimental models of disorders like Alzheimer's and Parkinson's disease, aiming to elucidate its capability to protect neuronal cells and support cognitive function. Further studies are necessary to expand on its pharmacokinetics and optimize its application potential in clinical settings.

Please enquire for more information about 7-[(Dimethylamino)methyl]-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-6-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2,7-Dimethyl-1-propyl-1H-indole-3-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(4-Ethoxyphenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Diuretic; cardiac stimulant; smooth muscle relaxant; bronchodilator

Please enquire for more information about 2-(4-Chlorophenyl)-6,8-dimethylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Bromo-2-(4-bromophenyl)-indole is a fine chemical with CAS No. 28718-96-9 that can be used as a versatile building block for the synthesis of complex compounds, useful scaffold for research chemicals, and reaction component for speciality chemicals. This compound has high quality and is a reagent in the synthesis of other compounds.

5-Methylindole-3-acetic acid (5MI3A) is a molecule that has been shown to have antiproliferative properties in bladder cancer cells. 5MI3A binds to the receptor for GABA, which is an inhibitory neurotransmitter. It also inhibits the production of proinflammatory mediators and reactive oxygen species in cancer cells. 5MI3A has anticancer activity in prostate cancer cells and may act by inducing apoptosis and inhibiting cell proliferation. Consumption of 5MI3A may reduce the risk of cancer development by preventing DNA damage from carcinogens, suppressing inflammation, and regulating cell growth through its antagonistic properties.

Please enquire for more information about 1-(4-Methylbenzyl)-1H-indole-6-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-[3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic acid methyl ester is a five-membered ring compound. It has organic solvents that can be screened for biological activity using high throughput screening. This compound is insoluble in water and reacts with bases, acids, and other compounds to form salts, benzoates, or crystallizing solids. The molecular conformation of this compound was determined by bioinformatics methods. It is a member of the class of 7-chloroquinoline derivatives that have been shown to inhibit Singulair (montelukast), an asthma drug. These agents are thought to bind to the active site of the enzyme cytochrome P450 and may also inhibit its ability to metabolize drugs such as acetaminophen and phenytoin.

Please enquire for more information about N-Benzyl-isoindoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Oxyquinoline Sulfate is used as a food preservative. References Gendy, A. et al.: Aud. J. Basic. App. Sci., 6, 260 (2012); Abou El-Ghait, E. et al.: Res. J. Agri. Biol. Sci., 8, 261 (2012);

Please enquire for more information about 8-[(2-Furylmethyl)thio]-5-nitroquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-(4-Methylphenyl)-1,2,3,4-tetrahydrocyclopent[b]indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-Bromoisoquinolin-3(2H)-imine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 3,4-Dihydroisoquinoline-6,7-diol acts as a reagent for the synthesis of 6,7-dihydroxy-3,4-dihydroisoquinline, a novel inhibitor factore-kB in invitro invasion in murine mammary cells. References Alvarez, F. N., et al.: Chemotherapy, 55, 175 (2009)

Isatin bis-cresol is a silicon-containing compound that can be used as a viscosity modifier and stabilizer in polymers. Isatin bis-cresol has shown resistance to degradation by water, alkali, and acid. It also has a high formation rate and can be used for the production of functionalized polymers such as polycarbonates or phosphonium salts. Isatin bis-cresol is insoluble in water but soluble in organic solvents, which makes it an ideal candidate for use in transesterification reactions. Isatin bis-cresol contains three functional groups: phenolic (OH), carboxylic acid (COOH), and alcohol (OH).

Please enquire for more information about 3-(Phenylsulfinyl)-1H-indole-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Chloro-6-methyl-1H-indole is a potential drug that acts as an allosteric modulator of the GABA receptor. 5-Chloro-6-methyl-1H-indole has been shown to increase the affinity of the sensor domain for GABA, which increases the sensitivity of the sensor domain to GABA and can reduce the frequency of spontaneous opening. 5-Chloro-6-methyl-1H-indole has also been shown to bind to allosteric sites on the GABA receptor and alter its function. It has been shown to be a potent antagonist of recombinant human α4β2 receptors with an IC50 value of 1 μM. The efficacy of this compound was tested in rat cortical neurons and its effects were confirmed by measuring changes in intracellular calcium levels.

4,5-Dimethoxyindole is a chemical compound that has been shown to exhibit radical scavenging activity. It is an inhibitor of integrase, which are enzymes involved in the integration of viral DNA into host cell chromosomes. This compound has been synthesized and its optical properties have been studied. The synthesis of 4,5-dimethoxyindole derivatives has also been investigated using molecular modeling. Schrodinger software was used to predict the geometry of these synthesized derivatives. These studies suggest that 4,5-dimethoxyindole may be a potential anti-cancer agent due to its ability to inhibit cancer cell growth and induce apoptosis.

Please enquire for more information about 7-Fluoro-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

8-Methoxy-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole is a versatile building block that can be used as a reagent or speciality chemical. It has been used in research and development of pharmaceuticals and as a useful intermediate for the synthesis of other compounds. 8-Methoxy-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole is an important reaction component for the synthesis of many types of compounds such as indoles, coumarins, and quinazolinones.

Applications 2-(2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL)ACETIC ACID (cas# 61164-71-4) is a useful research chemical.

Please enquire for more information about 6-Ethyl-2-(5-ethyl-2-thienyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Hydroxy-1-oxo-1,2-dihydroisoquinoline-3-carbohydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Chloroquinoline-6-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-Methyl-1H-indole-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-(4-Fluorophenyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Cyclopropyl-6-methylquinoline-4-carbohydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Chloro-2-(4-isobutylphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Methyl-1H-indazole-6-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5,6-Difluoro-1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Ethyl-2,6-dimethyl-1H-indole-3-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Phenanthridin-6(5H)-one is a chemical compound that has been shown to have pharmacokinetic properties in an experimental model. The sample preparation for the experiment was conducted using palladium-catalyzed coupling of phenanthridone with sodium carbonate. Phenanthridin-6(5H)-one demonstrated genotoxic activity by causing neuronal death in rats exposed to radiation or x-rays. The results of this study suggest that phenanthridon-6(5H)-one may be a potential therapeutic agent for treatment of cancer and neurological disorders.

Ethyl 7-bromo-4-chloroquinoline-3-carboxylate is an optimal inhibitor of protein kinase. It has been shown to inhibit the activity of both tyrosine and serine/threonine protein kinases. The compound inhibits the coupling of ATP to its natural substrate, which leads to inhibition of cellular activity. This product also inhibits enzymatic activity, specifically through the ethynyl group. The methoxy group prevents the binding of substrate and ATP, leading to a decrease in cellular activity.

Applications 6-Chloro-7-deazapurine Hydrochloride (cas# 1243346-92-0) is a compound useful in organic synthesis.

3-Cyclohexyl-1-[4-[2-(7-methoxy -4,4-dimethyl-1,3-dioxo-isoquinolin -2-yl)ethyl]phenyl]sulfonyl-urea is a drug that inhibits the enzyme DPPIV, which breaks down the incretin hormone glucagon-like peptide (GLP)-1. It may be used to treat diabetes by regulating blood glucose levels. This drug has been shown to reduce postprandial blood glucose levels in patients with type 2 diabetes. 3CYCSU is also capable of reducing body weight and food intake in mice. The mechanism of action of this drug is not fully understood, but it appears to have an effect on the cytosolic calcium ion concentration and may reduce inflammatory responses in cells. 3CYCSU is a promising potential treatment for infectious diseases such as Hepatitis C virus (HCV).