Composés polycycliques

Please enquire for more information about 5-Methyl-4,5,6,7-tetrahydro-2H-indazole-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Methylquinoline-4-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about [4-[(4-Methylpiperidin-1-yl)sulfonyl]-1-oxoisoquinolin-2(1H)-yl]acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about tert-Butyl 4-(quinolin-2-yl)piperazine-1-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Bromo-4-hydroxyquinoline is a synthetic compound that has been shown to inhibit the growth of cancer cells. The synthesis of 6-bromo-4-hydroxyquinoline is achieved by reacting 4,5,6,7-tetrabromoquinoline with hydroxylamine in the presence of a base. This process forms 6-bromo-4-hydroxyquinoline in high yield and purity. A number of studies have shown that 6-bromo-4-hydroxyquinoline inhibits tumor cell proliferation and induces apoptosis in vitro. It also exhibits antiangiogenic activity by inhibiting the PI3K/mTOR pathway and angiogenesis through the inhibition of VEGF production. 6 - bromo - 4 - hydroxy quinoline can be used as an effective chemotherapeutic agent for cancers such as breast cancer, melanoma, lung cancer, prostate cancer, and

5-Iodoisatin is a cross-coupling agent that has an inhibitory effect on tumor tissue. It is also used for the synthesis of conjugated drugs and pharmacological research. 5-Iodoisatin, which forms a ternary complex with copper and iodide, inhibits the growth of colorectal carcinoma cells by interfering with their DNA replication and protein production. 5-Iodoisatin can be converted to its active form through the formation of a ternary complex with copper and iodide ions. This inhibition is due to its ability to interact with DNA, RNA polymerase, and other proteins involved in transcription, translation, and replication processes. 5-Iodoisatin is metabolized through conjugation with glucuronic acid or sulfate in the liver; it binds to human mitochondrial DNA and can enter cells via passive diffusion. The carbonyl group in this drug may play an important role in its interaction with cancer cells.

Applications Indazole-3-carboxylic Acid is an indole derivatives useful in treatment of pain and inflammation. References Khanna P., et al.: Biochemistry, 40, 1441 (2001);

Please enquire for more information about 2-(3-Bromophenyl)-6,8-dimethylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

5,7-Dichloroindole is a synthetic chemical that has been used in the Buchwald-Hartwig cross-coupling reaction. It is generated by chlorination of an alkenyl or suzuki compound. The reaction proceeds via a chlorine atom transfer to the alkenyl or suzuki compound, which reacts with an amine to form the 5,7-dichloroindole product. The synthesis of this compound requires high temperatures and pressures and is therefore not cost effective for industrial use.

Please enquire for more information about 5-Bromo-1H-indazole-3-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Bicyclo[2.2.1]heptane-2,2-diyldimethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-(4-Bromo-3-hydroxy-2-Quinolinyl)-1,3-indandione is an organic compound that is used as a particle and polymerization initiator. It is reactive with fatty acids, metal hydroxides, and biological treatment. The 2-(4-Bromo-3-hydroxy-2-Quinolinyl)-1,3-indandione has a hydroxyl group that can be reacted with polymeric photoinitiators to form polymeric matrixes. This compound also reacts with hydroxy groups to form dry weight. Sodium hydroxide solution is the most commonly used for this reaction.

1-(3-Carboxypropyl)-3,7-dimethylxanthine is a drug that belongs to a class of drugs called multidrugs. It has been shown to inhibit the growth of endothelial cells by blocking the binding of tnf-α to its receptor on these cells. 1-(3-Carboxypropyl)-3,7-dimethylxanthine also inhibits cancer cell proliferation and has been shown to be effective in some human cancer models. This drug interacts with other molecules (e.g., proton) and can have significant effects on magnetic resonance spectroscopy assays as well as in humans.

Dihydroseselin (8,8-dimethyl-9,10-dihydropyrano[2,3-h]chromen-2-one) is a coumarin derived from the roots of Toddalia.

Please enquire for more information about 8-Chloro-2-(3-ethoxyphenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Quinolin-6-ylethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

8-Chloropurine is an anion of the molecule 8-chloropurine. It has a hydrogen peroxide group in its structure, which makes it reactive. 8-Chloropurine is acidic and can be used for analytical purposes. The 13C NMR spectroscopy analysis of 8-chloropurine has been shown to be able to differentiate between protonated molecules, such as acetonitrile and piperidine, and chloride ions. 8-Chloropurine has also been shown to react with acetonitrile and phosphorus oxychloride at different rates.

1,4-Diazabicyclo[2.2.2]octane bis(sulfur dioxide) adduct is a catalyst that can be used for the reduction of various functional groups. It is typically used to synthesize aziridines from amines and diazo compounds, or from halides and organometallic reagents. 1,4-Diazabicyclo[2.2.2]octane bis(sulfur dioxide) adduct has been shown to inhibit the production of sulfoxides by sulfide-reducing bacteria such as Desulfovibrio desulfuricans and Desulfobulbus propionicus.

Please enquire for more information about Benzyl 7'-chloro-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

[4-(4-Fluorophenyl)Sulfonylpiperazin-1-Yl]-[4-[[7-(Trifluoromethyl)Quinolin-4-Yl]Amino]Phenyl]Methanone (LAP) is a novel α2β3 antagonist that inhibits the angiotensin system. It has been shown to be effective at inhibiting the release of dopamine from rat primary hepatocytes and has no effect on the release of norepinephrine. This drug also blocks the binding of angiotensin II to its receptors, which results in decreased blood pressure and increased urine output. LAP is currently in clinical trials for testing its efficacy in treating heart failure.

tert-Butyl2,6-diazaspiro[3.5]nonane-6-carboxylate is the target compound in this experiment. It is a peroxide that can be synthesized by esterification of tert-butanol with 2,6-diazaspiro[3.5]nonane-6-carboxylic acid and hydrolysis of the resultant tert-butyl ester. The first step in this synthesis process is diazotization of aniline with sodium nitrite, followed by addition of hydrogen peroxide to produce the desired compound. The reaction produces hydroxylamine and oxidized tertiary amines as byproducts, which are then hydrolyzed with hydrochloric acid to produce tert-butyl2,6-diazaspiro[3.5]nonane-6-carboxylate.

Please enquire for more information about 7,8-Dimethyl-2-pyridin-2-ylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (3-Isopropoxypropyl)[(1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)methyl]amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Chloro-2-(4-ethoxyphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Applications 5-Amino-2H-isoquinolin-1-one is a reactant used in the synthesis of glucoorticoid receptor agonists as well as PARP inhibitors used in the treatment of tumors. References Berger, M. et al.: Bioorg. Med. Chem. Lett., 27, 437 (2017); Goodfellow, E. et al.: Bioorg. Med. Chem. Lett., 27, 688 (2017);

6,6'-Bis(chloromethyl)-2,2'-bipyridyl is a thermally stable and high-temperature catalyst that can be used to synthesize conjugates. It has been shown that 6,6'-bis(chloromethyl)-2,2'-bipyridyl is deactivated by chloride and homogeneous in the presence of sulfur. This catalyst also has high selectivity for the desired product and can be used at high temperatures for biomass conversion.

4,4'-Bis(methoxycarbonyl)-2,2'-bipyridine is a ligand that can be used in cross-coupling reactions. It has been shown to bind to metal ions and form complexes with the ligands. 4,4'-Bis(methoxycarbonyl)-2,2'-bipyridine has a constant value for maximizing the yield of the reaction and is luminescent. This product also has photophysical properties that allow it to be utilized in voltammetry studies. The transfer of this product can be optimized by using chromophores or catalysis. 4,4'-Bis(methoxycarbonyl)-2,2'-bipyridine provides a means for cross-coupling reactions using electrochemical studies and dichroism.

6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (6OHICA) is a compound that is an enantiopure of the natural product isoquinoline. It has been shown to be a potent modulator of nuclear receptors and can be used in drug development. 6OHICA binds to the enzyme lipase and inhibits its activity. This inhibition leads to an increase in the level of esters in organic solvents. The synthesis of 6OHICA is efficient and does not require any expensive or hazardous reagents. It has been synthesized as an enantiomerically pure form with yields of up to 100%. 6OHICA has also been found to be a good solvent for nuclear reactions.

2,6-Diaminopurine hemisulfate salt is a fine chemical that can be used as a building block for research chemicals, reagents, and specialty chemicals. It has been shown to be useful in the synthesis of various types of complex compounds. 2,6-Diaminopurine hemisulfate salt is also versatile in the sense that it can be used as an intermediate in reactions or as a scaffold for chemical synthesis. This product has CAS number 69369-16-0.

Please enquire for more information about 8-Methyl-2-(5-methyl-2-furyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

5,7-Dibromo-2-methyl-8-quinolinol (DBMQ) is a quinoline derivative that has been shown to have anticancer activity. It inhibits tumor cell growth and induces apoptosis by disrupting the mitochondrial membrane potential (Δψ) and mitochondrial functions. DBMQ also has high cytotoxicity, which makes it a promising candidate for diagnostic and therapeutic applications. The compound binds to aluminium ions with a coordination geometry similar to that of phosphate groups, thereby inhibiting the ATP synthase in the mitochondria. This inhibition leads to decreased production of ATP, causing cells to enter apoptosis. DBMQ has been shown to be effective in treating cancer cells that are resistant to common chemotherapeutic drugs such as cisplatin and doxorubicin.

Please enquire for more information about 1-(4-Fluorobenzyl)-1H-indole-6-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Cleomiscosin A, from Acer okamotoanum, inhibits mouse TNF-α and may prevent LDL oxidation in atherosclerosis.

Please enquire for more information about Dimethyl 2-(6-ethyl-2,2-dimethyl-3-thioxo-2,3-dihydroquinolin-4(1H)-ylidene)-1,3-dithiole-4,5-dicarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-(4-chlorophenyl)spiro[1,3-thiazolidine-2,3'-indoline]-4,7-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Xanthotoxol is a naturally occurring furanocoumarin, which is derived from various plant species, primarily within the Apiaceae family. This compound exhibits its biological activity through several mechanisms, including the inhibition of enzyme pathways, modulation of signaling pathways, and interaction with cellular proteins, impacting various physiological processes. Xanthotoxol is used predominantly in scientific research, exploring its potential therapeutic applications. It has been studied for its anti-inflammatory, antioxidant, and anticancer properties. In inflammation studies, Xanthotoxol has demonstrated an ability to suppress pro-inflammatory cytokines and inhibit pathways like NF-κB. As an antioxidant, it scavenges free radicals, thereby protecting cells from oxidative stress. Additionally, its anticancer effects have been observed in various cell line studies, where it induces apoptosis and inhibits cell proliferation. These properties make Xanthotoxol a compound of interest for further pharmacological research and potential drug development.