Composés polycycliques

Flucindole is a diagnostic agent that can be used to diagnose psychiatric patients. Flucindole is an antagonist at the serotonin transporter gene and has been shown to be effective in treating depression. Flucindole is a n-oxide of fluoxetine, which is an antidepressant drug. Flucindole also inhibits fatty acid synthase, which synthesizes fatty acids from acetyl-CoA. The inhibition of this enzyme leads to a decrease in the production of fatty acids and results in weight loss for obese patients.

Please enquire for more information about 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-(5-Methyl-Thiophen-2-Yl)-1H-Indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about N-{2-[(2-Methyl-1,2,3,4-tetrahydroquinolin-8-yl)oxy]ethyl}acetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Methyl-2-(3-propoxyphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Amino-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Methyl-1H-indazole-5-boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about [2,3'-Bipyridine]-6-carboxylic acid - Technical including the price, delivery time and more detailed product information at the technical inquiry form on this page

5,5'-Dibromo-2,2'-bipyridyl is a bidentate ligand that can be used for the homocoupling of alkyl halides. It has been shown to be a catalyst for the coupling of Xylene and Binap with high yield. This ligand can also be used in palladium catalysts to promote the hydrogenation of unsaturated molecules. The reaction rate of 5,5'-dibromo-2,2'-bipyridyl is dependent on its conformation. Crystals are more reactive than powder and solution. 5,5'-Dibromo-2,2'-bipyridyl will react with solvents such as benzene or xylene at room temperature and pressure.

Please enquire for more information about 6-Ethyl-2-pyridin-2-ylquinoline-4-carbonyl chloride hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(4-Aminophenyl)-6-ethylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-(1,10-Phenanthrolin-5-yl)iodoacetamide (NPA) is a coordination complex that has been shown to bind to the minor groove of dna. This binding prevents the separation of the two strands of DNA and inhibits replication. NPA also inhibits bacterial growth by binding to dna replication proteins, such as the DNA polymerase and helicase. NPA may be useful in the treatment of bacterial infections that are resistant to other antibiotics due to its ability to inhibit bacterial dna synthesis.

Please enquire for more information about 2-[4-(Carboxymethoxy)phenyl]quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1,8-Dimethyl-4,5-dihydro-1H-isoxazolo[5,4-g]indazole-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

1-Boc-3-iodo-1H-indazole is a synthetic compound that has been shown to function as an ancillary drug in the treatment of fungal infections. It inhibits calcineurin, which is necessary for the production of cytokines in mammalian cells. 1-Boc-3-iodo-1H-indazole also inhibits chloride transport and causes sublethal damage to yeast cells. 1-Boc-3-iodo-1H-indazole is not active against Saccharomyces cerevisiae, but does inhibit the growth of Candida albicans and other strains of yeasts. 1,3,5,7,9b,-hexahydrobenzo[a]cyclooctene assays have been used to test the efficacy of this drug for use in antifungal therapy.

Please enquire for more information about Methyl 3,7-dimethyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Nitro-3-methyl-9H-pyrido[2,3-b]indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

5H-[1,2,4]Triazino[5,6-b]indole-3-thiol (TATI) is a β-cyclodextrin that can be used as a catalyst for the synthesis of anilines. It has been shown to be an inhibitor of thiosemicarbazide and catalytic in the presence of halides. TATI also has minimal inhibitory concentrations against Sulfur bacilli and Staphylococcus aureus. It is not active against Gram-negative bacteria such as Escherichia coli or Pseudomonas aeruginosa. TATI is synthesized by reacting elemental analysis with thione and then reacting this with anilines in the presence of sulfoxide. The yield is around 40%.

Please enquire for more information about 1-(Methylsulfonyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

1,4-Dichloropyrido[4,3-d]pyridazine is a metabolic antagonist that inhibits the activity of the smoothened protein. It is used to treat childhood cancers and is effective against mouse pyridopyridazine. 1,4-Dichloropyrido[4,3-d]pyridazine has shown to have a high metabolic stability and is eliminated through the urine. This drug also has a pharmacodynamic model that can be used to optimize its potency.

Please enquire for more information about 8-Bromoquinoline-3-carboxylic acid hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-(Hydroxymethyl)bicyclo[2.2.2]octane-1-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1'-Oxo-2'-phenyl-1',4'-dihydro-2'H-spiro[cyclohexane-1,3'-isoquinoline]-4'-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Lactone

8-Chloroquinoline is an organochlorine compound that has anti-malarial, anti-parasitic, and anti-bacterial properties. It binds to the parasite's enzyme hemozoin synthase to inhibit the production of hemozoin. 8-Chloroquinoline also inhibits bacterial growth by binding to the enzyme DNA gyrase and prevents bacterial replication. The binding of 8-chloroquinoline to DNA gyrase inactivates it, thus preventing supercoiling of the bacterial DNA. This causes a structural change in the DNA helix that inhibits transcription and replication. 8-Chloroquinoline has been shown to be effective against Mycobacterium tuberculosis with minimal toxicity for liver cells.

Please enquire for more information about 3-Boc-8-oxo-3-azabicyclo[3.2.1]octane including the price, delivery time and more detailed product information at the technical inquiry form on this page

6,7-Bis-(d3)-methoxy-3,4-dihydroisoquinoline (N-1) is a compound that has been used to study the photophysical properties of molecules. It can be synthesized by demethylation and allylation of 6,7-bis-(d3)-methoxy-3,4-dihydroisoquinoline (N). This compound has two methoxy groups on the benzene ring. The chemical reactions are carried out in the presence of phosphotungstic acid and hydrochloric acid. The structural analysis was done by using halides. 6,7-Bis-(d3)-methoxy-3,4-dihydroisoquinoline (N) is also known as dimethyl fumarate or maleate.

Please enquire for more information about Methyl 6-nitro-3,4-dihydroquinoline-1(2H)-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page