Hydrocarbures aromatiques polycycliques (HAP)

Applications 3-Nitroacenaphthene is an impurity of Acenaphthene (D448330), which is a polycyclic aromatic hydrocarbon as carcinogenic agent. References Liu, Y., et al.: J. Med. Chem., 57, 5203 (2014);

Applications Naphtho[2,3-e]pyrene is a polycyclic aomatic hydrocarbon (PAH) with carcinogenicity. Naphtho[2,3-e]pyrene is one of the C24H14 PAH that displayed mutagenicity in human cells expressing CYP1A1. References Yan, L.S.: Carcinogenesis6, 1 (1985); Durant, J.L. et al.: Mutat. Res. Gen. Toxicol. Environ. Mutagen., 446, 1 (1999);

Applications 8-Hydroxybentazone, is a metabolite of Bentazon, a selective post-emergence herbicide. References Kim, J., et al.: ACS Symp. Series, 899, 92 (2005); Roper, J., et al.: Wat. Res., 29, 2720 (1995);

Applications trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene is a metabolite of Benzopyrene (B205800). Benzo[a]pyrene (B205800), a prototypic PAH, is metabolized by cytochrome P 450 1A1/1B1. (-)-trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene (D452280) undergoes further P 4501A1/1B1-mediated metabolism to a carcinogen, which forms DNA-adducts primarily with 2'-deoxyguanosine. A carcinogen. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Gelhaus, S. et al: Chem. Res. Toxicol., 24, 89 (2011); Belvedere, G. et al.: Biochem. Pharmacol., 29, 1693 (1980); Jennette, K. et al.: Biochem. Pharmacol., 28, 338 (1979); Yagi, H. et al.: J. Am. Chem. Soc., 99, 2358 (1977)

Applications Fluoren-3-ol-d9 is the labeled analogue of Fluoren-3-ol (F462460), a urinary monohydroxylated metabolite of polycyclic aromatic hydrocarbons (PAH) that is used for biomonitoring human exposure to PAH. References Li, Z., et. al.: Chem. Res. Toxicol., 25, 1452 (2012)

Applications 7-Aminobenzo[a]pyrene (cas# 72297-05-3) is a compound useful in organic synthesis.

Applications 1-ETHYLNAPHTHALENE (cas# 1127-76-0) is a useful research chemical.