Hydrocarbures aromatiques polycycliques (HAP)

Applications 1,2,8-Trimethyl-phenanthrene is an isomer of 1,2,6-Trimethylphenanthrene which is a persistent organic pollutant (POP). References Bratberg, M., et al.: Chemosphere, 90, 2157 (2013)

Applications 5-Methylchrysene is one of the methylated chrysenes (MeChry), as an aryl hydrocarbon receptor (AhR) agonist. Methylated chrysenes (MeChry) are important cigarette smoke constituents and 5-MeChry has been listed as possibly carcinogenic to humans. 5-Methylchrysene is a possible carcinogenic agent. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Amin, S., et al.: Cancer Res., 45, 6406 (1985), Blaha, L., et al.: Toxicol. Sci., 65, 43 (2002), Brack, W., et al.: Environ. Sci. Technol., 37, 3062 (2003), Andrysik, Z., et al.: Mutat. Res., 615, 87 (2007),

Applications A naturally abundant pneumotoxin, found primarily in mammalian feces providing its strong fecal odor. In lower concentrations however, the compound has a pleasent aroma, giving orange blossoms and jasmine their pleasing scent. It is often a component of commercial fragrances and perfumes. This compound is a contaminant of emerging concern (CECs) Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Nakashima, T., et al.: Biol. Pharm. Bull., 32, 832 (2009), Xu, H., et al.: Chem. Pharm. Bull., 57, 321 (2009), Bodoor, K., et al.: J. Med. Chem., 52, 3753 (2009), Naskar, S., et al.: J. Chem. Res., 3, 174 (2009), Sollner, K., et al.: J. Agric. Food Chem., 57, 4319 (2009),

Applications A urinary metabolite from inhalation and dermal exposure to polycyclic aromatics hydrocarbons in hot mix asphalt paving workers. A heterocyclic aromatic compound with potent mutagenic and carcinogenic properties.One of the azaarenes found in grilled meat. References Smith, C.J., et al.: Food Chem. Toxicol., 38, 637 (2000), Koehler, D.A., et al.:; J. Ind. Ecol., 9, 143 (2005), Arnot, J.A., et al.: Environ. Toxicol. Chem., 27, 341 (2008),

Applications Naphthalene-d8, is the labeled analogue of Naphthalene, a polycyclic aromatic hydrocarbons as micropollutants. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Di Toro, D., et al.: Environ. Toxicol. Chem., 19, 1971 (2000), Vines, C., et al.: Aquat. Toxicol., 51, 225 (2000), Incardona, J., et al.: Toxicol. Appl. Pharmacol., 196, 191 (2004), Junghans, M., et al.: Aquat. Toxicol., 76, 93 (2006),

Applications 2,6-Dimethylnaphthalene is a polyaromatic hydrocarbon (PAH) environmental contaminant. 2,6-Dimethylnaphthalene is found in oil, coal and tar deposits and are produced by gasoline operating vehicles. It is a persistent environmental pollutant with carcinogenic and mutagenic activity.This compound is a contaminant of emerging concern (CECs) Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Hays, M. et al.: Environ. Sci. Tech., 47, 14502 (2013); Lemieux, C. et al.: Environ. Toxicol. Chem., 27, 978 (2008); Gruger, E., et al.: Aquat. Toxicol., 5, 291(1984); Barnsley, E.: Appl. Environ. Microb., 54, 428 (1988); Miyachi N., et al.: Environ. Toxicol. Chem., 59, 1504 (1993)

Stability Light Sensitive Applications Benz[l]aceanthrylene is a mutagenic agent. References Bartczak, A., et al.: Mutagenesis, 2, 101 (1987); Nesnow, S., et al.: Cancer Res., 44, 4993 (1984)

Applications Benzo[b]thiophene has application in organic as well as pharmaceutical industry as a component in the synthesis of Raloxifene, a breast cancer therapeutic, or hydrodesulfurization reactions. References Buccella, D. et al.: J. Am. Chem. Soc., 130, 16187 (2008); Gennari, L. et al.: Exp. Opin. Drug Saftey, 7, 259 (2008);

Applications Anthracene-d10 is an isotope labelled analogue of Anthracene (A678400), an polycyclic aromatic hydrocarbon found readily as an component in coal tar. Anthracene is also used in the preparation of various dyes. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Dibenzofuran is a reagent in Friedel-Crafts acylation. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Albrecht, W. L., et al.: J. Med. Chem., 20, 364 (1977);

Applications Benzo[e]pyrene-d12 (CAS# 205440-82-0) is a useful isotopically labeled research compound.

Applications 3-Methylfluoranthene is an environmental pollutant that is an active tumor initiator. References LaVoie, E.J., et. al.: Carcinogenesis, 15, 2131 (1994)