Alcaloïdes d'opiacés

Applications Analgesic (narcotic); antitussive. Mydriatic.Controlled substance. References Ertl, P., et al.: J. Med. Chem., 43, 3714 (2000), Jones, A., et al.: Toxicol. Rev., 25, 15 (2006), Schwilke, E., et al.: J. Forensic Sci., 51, 1191 (2006),

Applications Controlled substance (opiate). Analgesic (narcotic). References Ananthan, S., et al.: J. Med. Chem., 47, 1400 (2004), Gimbel, J., et al.: Anesth. Analg., 99, 1472 (2004), Adams, M., et al.: J. Clin. Pharmacol., 45, 337 (2005),

Impurity Dextromethorphan EP Impurity B Applications A metabolite of Dextromethorphan (D299455). References Karler, R., et al.: Brain Res., 582, 143 (1992), Klein, M., et al.: J. Pharmacol. Exp. Ther., 260, 990 (1992), Gorski, J., et al.: Biochem. Pharmacol., 48, 173 (1994),

Applications An analgesic derivative of the synthetic μ-opiate agonist (R)-Methadone (M225880) and a precursor of β-Acetylmethadol. It does not evoke heroin-like discriminative stimulus effects unlike other methadone derivatives. It has inhibitory effect on 5-Hydroxytryptamine (H974990) uptake. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Newman, J.L. et al.: Psychopharmacol., 164, 108 (2002); Brase, D.A. et al.: Biochem. Pharmacol., 25, 1684 (1976); Casy, A.F. et al.: J. Med. Chem., 11, 601 (1968);

Applications 6-Acetylmorphine 3-O-β-D-Glucuronide is the glucuronide conjugate of 6-Acetyl Morphine (A186900 and a metabolite of Heroin (H281180). References Yeh, S.Y. et al.: J. Pharmac. Sci., 66, 201 (1977); Crews, B. et al.: Therap. Drug. Mon., 31, 749 (2009);

Applications Benzoyl Fentanyl is a derivative compound of Fentanyl (F274990), used as an analgesic and also a controlled substance. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Zernig, G., et al.: Life Sci., 57, 2113 (1995), Bot, G., et al.: J. Pharmacol. Exper. Therap., 285, 1207 (1998),

Applications The major metabolite of Thebaine. Oripavine possesses an analgesic potency comparable to Morphine; it is not clinically useful due to severe toxicity and low therapeutic index. An opiate. References Barber, R., et al.: J. Med. Chem., 18, 1074 (1975), Yamazoe, Y., et al.: J. Pharmacol., 31, 433 (1981),

Applications β'-Phenyl Fentanyl is a potent analgesic and a derivative compound of the controlled substance Fentanyl (F274990). Fentanyl Analog. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Zhu, Y., et al.: Yaoxue Xuebao, 16, 199 (1981); Zernig, G., et al.: Life Sci., 57, 2113 (1995); Bot, G., et al.: J. Pharmacol. Exper. Therap., 285, 1207 (1998);

Applications The labelled cis-isomer of Mefentanyl; an opiate.Controlled substance. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Riley, T.N., et al.: J. Pharm. Sci., 62, 983 (1973), Gillespie, T.J., et al.: J. Anal. Toxicol., 6, 139 (1982),