Antibiotiques

4x25kg

Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.

A semi-synthetic beta-lactamase inhibitor

Sulfamonomethoxine is a long-acting sulfonamide antibacterial agent, blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.

Applications Carbapenem is an antibiotic and antibacterial. References Sunagawa, M., et al.: J. Antibiot., 43, 519 (1990), Hurst, M., et al.: Drugs, 59, 653 (2000),

Sulfacetamide treats blepharitis, conjunctivitis, mild hidradenitis suppurativa, and acne by inhibiting bacterial folic acid.

Sulfamethizole (Sulfamethizol) is a sulfathiazole antibacterial reagent.

Ethambutol is an antimicrobial compound, specifically an antitubercular agent, which is a synthetic derivative of ethylenediamine. It is classified as a bacteriostatic agent that primarily targets Mycobacterium tuberculosis. The mode of action of Ethambutol involves the inhibition of arabinosyl transferases, enzymes essential for the polymerization of arabinogalactan, a critical component of the mycobacterial cell wall. By disrupting cell wall biosynthesis, Ethambutol effectively hampers the growth and proliferation of the bacteria. The primary application of Ethambutol is in the treatment of tuberculosis (TB), often used in combination with other antitubercular drugs to prevent the emergence of drug resistance. This agent has proven efficacy in both pulmonary and extrapulmonary TB infections. Its use is critical in multi-drug therapy regimens, optimizing treatment outcomes and reducing the prevalence of resistant TB strains. Ethambutol’s role in the antituberculosis pharmacopoeia extends its utility to atypical mycobacterial infections as well, marking it a significant tool in the clinical management of mycobacterial diseases.