Hétérocycles oxygénés (O)

Please enquire for more information about 2-Chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-6-phenylpurine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 2-Propenylfuran (cas# 75135-41-0) is a useful research chemical. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Please enquire for more information about 5-(5,6,7,8-Tetrahydro-4H-cyclohepta[b]thien-3-yl)-4-(tetrahydrofuran-2-ylmethyl)-4H-1,2,4-triazole-3-thiol including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(Isocyanatomethyl)tetrahydrofuran including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about N-(2,3-Dihydro-1-benzofuran-2-ylmethyl)-N-ethylamine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about [4-[2-(Diethylamino)ethoxy]-3-iodophenyl][2-(1-hydroxybutyl)-3-benzofuranyl]-methanone including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Zirconocene Bis(trifluoromethanesulfonate) Tetrahydrofuran Adduct including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Bromofuran is a metal carbonyl and a pyrazole ring. It has been shown to bind to the CB2 receptor and may have some activity on the nervous system. 2-Bromofuran has been shown to be effective in treating chronic kidney disease and polycystic ovarian syndrome with acetylcholine. The electrochemical data for this molecule has shown that it can form hydrogen bonds when combined with cholinergic molecules.

2,3-Dihydrobenzofuran is a chemical that is used as an industrial solvent. It is synthesized by the reaction of ethyl chloroformate and borohydride, followed by the addition of acetonitrile. The product is then tosylated with carboxylic acid and basified with chloroformate. Decarboxylation of the carboxylic acid results in 5-(2-bromoethyl)-2,3-dihydrobenzofuran. This compound can also be synthesized from 2-chlorobenzaldehyde and sodium borohydride in chloroformate. The final product can be isolated using chlorination or sodium borohydride.

3-Methylfuran is a chemical that is used as an insecticide. It is a solid at room temperature and has a molecular weight of 162.24 g/mol. 3-Methylfuran can be found in the form of crystals or powder, which can be dissolved in acetone, alcohol, or chloroform. 3-Methylfuran has been shown to have toxic effects on the liver and proximal tubules in rats when given orally at high doses. The toxic effects were due to oxidative stress caused by reactive oxygen species (ROS) production. 3-Methylfuran also reacts with fatty acids to produce methyl ketones, which are thought to be responsible for some of its toxicity.

Applications 6-Amino-5-(1,1-dimethylethyl)-3,3-dimethyl-2(3H)-benzofuranone is an intermediate in synthesizing Ivacaftor Carboxylic Acid (I940605). It is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis. References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)

Please enquire for more information about 4-Ethoxy-1-benzofuran-6-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-Furan-2-Yl-1H-Indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

7-Amino-3-methyl-1(3H)-isobenzofuranone is a biphasic solvent that was synthesized to be used as an efficient and scalable synthesis catalyst for the hydrogenation of a variety of organic compounds. 7-Amino-3-methyl-1(3H)-isobenzofuranone has been shown to be an efficient catalyst in the hydrogenation of various intermediates, including paquinimod.

5-Fluoro-1-(2'-Fluoro-2'-Deoxyribofuranosyl)Uracil (5FU) is a pyrimidine analog that is used in the treatment of cancer. It is usually given intravenously to patients with metastatic colorectal cancer. 5FU is an inhibitor of thymidylate synthase and dihydrofolate reductase, which are enzymes involved in DNA synthesis. The drug also inhibits the production of uracil, which results in the inhibition of RNA synthesis and protein synthesis. This leads to tumor cell death by apoptosis or necrosis. 5FU also has been shown to have a direct cytotoxic effect on lung tumor cells, as well as other analogues such as 2'-fluoro-5-methyl-4(3H)-pyrimidinone and 5,5'-difluorouracil (5DFUR).

Please enquire for more information about (3aR,4R,5R,6aS)-hexahydro-5-hydroxy-4-(3-oxo-1-decenyl)-2H-cyclopenta[b]furan-2-one 5-(4-phenylbenzoate) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-(Allyloxy)-1-benzofuran-6-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 2-Acetylfuran is a widely used reagent in manufacturing pharmaceuticals and aroma compounds. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Bertero, M., et al.: Fuel, 95, 263 (2012); Dang, Q., et al.: J. Medn. Chem., 54, 153 (2011); Candu, N., et al.: Topics. Catalysis., 52, 571 (2009);

Please enquire for more information about 5-Hydroxy-4-propyl-2(5H)-furanone including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Ethyl 3-benzofuran-2-yl-3-oxo-propionate including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-butan-2-yl-1-[5-[(3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carbonyl)amino]-2-fluorophenyl]N-methylisoquinoline-3 carboxamide (BDZM) is a benzodiazepine receptor ligand that has been shown to be potent and selective for the benzodiazepine receptor. BDZM has been shown to bind reversibly to the receptor and block chloride ion channels in neuronal tissue. This compound also has other binding sites, including an amino acid site, but these sites are not as prevalent. BDZM has been shown to have no effect on rat renal membranes or histidine fluorescence techniques.

Applications 5-Bromo-7-ethyl-2-formyl-benzofuran (cas# 137206-73-6) is a compound useful in organic synthesis.

2-Butylfuran is a synthetic, furanic compound that is used as a stable complex for use in homogeneous catalysts. The reaction of 2-butylfuran with palladium chloride has been shown to generate the corresponding palladium complexes. These complexes have been found to be efficient in the cross-coupling of organic compounds. The chemical reactions are also efficient with respect to animals and fatty acids. FT-IR spectroscopy has been used for determining if the 2-butylfuran is present in animal fat or plant oil. This technique has also been used to identify the presence of fatty acid weevils in plants.

Dibenzo[b,d]furan-2-carbonitrile is a potent aromatase inhibitor that inhibits the production of estrogen by binding to the aromatase enzyme. Dibenzo[b,d]furan-2-carbonitrile has been shown to be effective in treating endometriosis, which is characterized by an overproduction of estrogen. This drug also has chemokine and progesterone receptor modulating activity, which may play a role in its therapeutic effectiveness. It can also be used for hormone replacement therapy or as an adjunct to other treatments for breast cancer and prostate cancer. Dibenzo[b,d]furan-2-carbonitrile binds to the extracellular domain of the human growth factor receptor (GR) with high affinity and specificity. The interaction with this receptor leads to inhibition of cell proliferation and tumorigenesis.

Please enquire for more information about 5-Methyl-3-(phenylmethylene)-2(3H)-furanone including the price, delivery time and more detailed product information at the technical inquiry form on this page

Ethyl(5-bromobenzofuran)-2-carboxylate is a reactive intermediate that is used in organic synthesis. It can be prepared by the reaction of tert-butylbenzene with ethylene dibromide, followed by hydrolysis of the tert-butoxy group. This compound has been shown to be an efficient catalyst for coupling reactions involving carboxylates and potassium tert-butoxide.

Please enquire for more information about 7-Acetyl-2,3-dihydrobenzofuran including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Benzoyl-1-benzofuran-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about tert-Butyl 5-chloro-3-oxo-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Furan-2-carboxamidine is a heteroaryl compound that is used in the treatment of inflammatory bowel disease. Furan-2-carboxamidine has been shown to reduce the severity of bowel inflammation by inhibiting the production of nitric oxide, which plays a role in the development of bowel disease. The drug may also inhibit adenosine receptor antagonists and adenosine, which are involved in regulating nerve cell activity. Furan-2-carboxamidine also inhibits dyskinesia and reduces the severity of Parkinson's disease. This drug is not soluble in water but can be solvated with hydrochloric acid or furfural. Furan-2-carboxamidine does not react with hydroxylamine under basic conditions, but reacts at pH values less than 7.

5-Methoxyisobenzofuran-1,3-dione is an isomer of a molecule that has been identified as a possible cholinesterase inhibitor. It inhibits the enzyme acetylcholinesterase and the synthesis of neurotransmitters such as acetylcholine. 5-Methoxyisobenzofuran-1,3-dione binds to the active site of the enzyme and forms a covalent bond with the serine hydroxyl group. This modification prevents the hydrolysis of acetylcholine by cholinesterase and leads to rapid accumulation of acetylcholine at synapses. The structural modifications that lead to this inhibition can be achieved by using synthetic methods or by enzymatic reactions. The aromatic ring in 5-methoxyisobenzofuran-1,3-dione is activated with a Grignard reagent to produce an ether linkage which may help stabilize the molecule in

Please enquire for more information about (2,4-Dinitrophenyl)(tetrahydrofuran-2-ylmethyl)amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-(Fmoc-2-aminoethyl)-6-dibenzofuranpropionic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (3R,4R,5R)-5-(Acetoxymethyl)-3-methyltetrahydrofuran-2,3,4-triyltriacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about N-[(1S)-1-[[[(4R,7S)-Hexahydro-7-methyl-3-oxo-1-(2-pyridinylsulfonyl)-1H-azepin-4-yl]amino]carbonyl]-3-methylbutyl]-2-benzofurancarb oxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-Oxo-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-O-Benzoyl-3-Deoxy-3-Fluoro-1,2-O-Isopropylidene-alpha-D-Glucofuranose is a polar compound that is used to study the uptake and assaying of respiratory enzymes. It has been shown to inhibit oxygen uptake in isolated rat liver mitochondria. This compound also inhibits oxidative phosphorylation by inhibiting mitochondrial enzymes activities, including succinate dehydrogenase and cytochrome c oxidase. 6ODGF can be used to determine the role of respiratory chain in mitochondrial ATP production.

Please enquire for more information about 4-Amino-6-bromo-5-cyano-7-(3-azido-3-deoxy-2-O-acetyl-5-(O-p-toluoyl)-beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

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M02244 - Penitrem A, Penicillium paxilli

5-(3-Aminoallyl)-2′-deoxyuridine 5′-triphosphate is a fluorescent nucleotide analog that can be used as a probe for detecting hybridization. This chemical has been shown to be sensitive and specific for the detection of DNA sequences in the range of 10-1000 base pairs. 5-(3-Aminoallyl)-2′-deoxyuridine 5′-triphosphate is labeled with fluorescein, which can be detected using a microscope or spectrometer. The primary amines on this probe are attracted to the amines found in DNA and RNA, which results in hybridization. This probe is most efficient when it is bound to an immobilized target sequence on a solid support such as nitrocellulose or nylon membrane.

2-(2-Methoxyphenyl)-5-oxotetrahydrofuran-3-carboxylicacid is a carboxylic acid that can be synthesized from 2-(2-methoxyphenyl) tetrahydrofuran and succinic anhydride. The product yield is high, and it has been used as an industrial nematicide. In addition, this compound can be used as a synthetic intermediate for the production of guanidine and zinc chloride. 2-(2-Methoxyphenyl)-5-oxotetrahydrofuran-3-carboxylicacid is also known to have antiinflammatory properties.

Applications 2,3-Dihydro-2,2,4,6,7-pentamethylbenzofuran is an 2,3-Dihydrobenzofuran derivative which is an important intermediate of medicines and agricultural chemicals. References Kim, H. J., et al.: Hwahak Konghak, 43, 662-667 (2005)

Please enquire for more information about 5,6-Dihydro-3-(methylamino)-2H-1,4-thiazin-2-one O-[[5-[(dimethylamino)methyl]-2-furanyl]methyl]oxime including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Methylbenzofuran-2-carboxylic acid is a dianion that binds to the cell membrane and inhibits bacterial growth. This compound has been shown to be active against bacteria at low concentrations. 3-Methylbenzofuran-2-carboxylic acid has been used as an antibacterial agent for the treatment of gram-negative bacteria such as Escherichia coli and Proteus mirabilis. It also inhibits the growth of gram-positive bacteria including Staphylococcus aureus, Streptococcus pneumoniae, and Enterococcus faecalis. The reaction temperature required for the synthesis of this compound is high, but it can be prepared at lower temperatures by using anhydrous acetonitrile in place of hydrochloric acid.

1-Benzofuran-3-ylacetonitrile is an anti-cancer drug that belongs to the class of benzofurans. It has been shown to inhibit the growth of cancer cells and induce apoptosis, which is a programmed cell death. 1-Benzofuran-3-ylacetonitrile inhibits the synthesis of DNA and RNA by inhibiting the activity of specific enzymes (topoisomerase II, DNA polymerase) in the process. One study showed that this compound had a significant effect on cancer cells in mice and inhibited tumor growth when used in combination with vinblastine. The research also indicated that 1-(benzofuran-3-yl)acetonitrile was more effective than other benzofuran derivatives because it was more photostable and had lower toxicity to healthy cells.

Tetrahydrofuran-2,3,4,5-tetracarboxylic acid (THF-TTCA) is a polycarboxylic acid that can be extracted from coal tar. It has a number of uses as an extractant in the production of polycarbonates and other plastics. Tetrahydrofuran-2,3,4,5-tetracarboxylic acid has been shown to crystallize from solution at high temperatures and pressures. The crystal structure of THF-TTCA consists of a ring of six carboxylate groups with three molecules of water coordinating to form hydrogen bonds. Tetrahydrofuran-2,3,4,5-tetracarboxylic acid has the structural analog of the metal ion tetraammineborane (NHBH). This compound is acidic and binds strongly to metal ions such as copper(II) or cobalt(III

2-Nitrofuran is a nitrofuran that is used as a pharmacological agent and also as a matrix effect in biological samples. The rate constant of 2-nitrofuran has been determined by squamous cell carcinoma cells, which have shown an increased rate of DNA synthesis due to the presence of this drug. Nitrofurans are also known to have antiinflammatory activity. 2-Nitrofuran has been shown to inhibit the growth of Candida glabrata, an opportunistic fungal pathogen, in vitro and in vivo. This drug can be detected using analytical methods such as chromatography or colloidal gold.

Please enquire for more information about 4-[(furan-2-ylmethyl)sulfonyl]piperidine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

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