Building Blocks

(1-Ethenyl-1H-imidazol-2-yl)methanol is a heterocyclic compound with a triazole ring. It is a cyclic imide that contains an imidazole ring and a methyl group, giving it the properties of an azide. The molecule yields hydroxymethyl groups and has been used in the synthesis of triazolyl compounds. This molecule can be prepared by reacting benzaldehyde with hydrochloric acid to form benzyl chloride, which is then reacted with ammonia to produce (1-ethenyl-1H-imidazol-2-yl)methanol. Heterocycles are molecules containing at least one heteroatom such as nitrogen, oxygen, or sulfur. They are often unsaturated rings or rings containing two or more different types of atoms and may be found in drugs or other organic compounds.

4-Nitropyridine-3-carboxylic acid

Versatile small molecule scaffold

3H,4H,5H-Pyridazino[4,5-b]indol-4-one is a drug that has been shown to inhibit the angiogenic activity of endothelial cells. It also inhibits the production of factor receptor by cancer cells, which may be responsible for its anti-cancer effects. 3H,4H,5H-Pyridazino[4,5-b]indol-4-one also inhibits the growth of endothelial cells and reduces the formation of new blood vessels in an experimental model of angiogenesis. This drug has been shown to have a protective effect on neuronal cells in an animal model of Alzheimer's disease. 3H,4H,5H-Pyridazino[4,5-b]indol-4-one can be used as a treatment for diabetes mellitus type II and diabetic neuropathy because it is believed to promote the regeneration of nerve fibers by blocking the

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2,3,4,5,6-pentachloropyridine

Versatile small molecule scaffold

8-(Difluoromethoxy)-5-nitroquinoline

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Piperidine-4-carbonitrile hydrochloride

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4,4'-Dithiopyridine is a reactive molecule that can be used in the synthesis of other organic compounds. It is a disulfide bond with a redox potential of -0.43 V, which makes it readily available for reaction. The structural analysis of 4,4'-dithiopyridine has been performed using NMR spectroscopy and gas chromatography/mass spectrometry (GC/MS). This compound is an inhibitor of sugar transport and can be used to study the p-nitrophenyl phosphate reductase enzyme in bacteria. The reaction product between 4,4'-dithiopyridine and NADPH cytochrome P450 produces the fluorescent molecule 2-aminopurine. This fluorescent molecule may be used as a probe to study transfer reactions in bacteria.

2-Cyano-N-(4-methoxyphenyl)acetamide is a synthetic compound with inhibitory effects on the enzyme dipeptidyl peptidase IV (DPP-IV). This enzyme is involved in the degradation of incretins, such as glucagon-like peptide 1 (GLP-1), and has been implicated in the development of type 2 diabetes mellitus. The synthesis and characterization of this compound was reported in a paper published in 2000. It has been shown to be a potent inhibitor of DPP-IV, with IC50 values of 0.10 μM for rat pancreatic DPP-IV and 0.06 μM for human recombinant enzyme. The effects of this compound on GLP-1 levels were also studied, showing that it had no effect on basal levels but significantly increased postprandial GLP-1 secretion.

Versatile small molecule scaffold

Versatile small molecule scaffold

2-(Piperidin-1-yl)quinoxaline is a piperidine derivative that has been synthesized by catalyzed reactions. It has been shown to have constant kinetic parameters and an optimum in the range of 1.0-2.0 M in solvents with the following properties: polar, protic, or ionic. 2-(Piperidin-1-yl)quinoxaline has also been shown to exhibit solvent effects on its spectra, kinetics, and optimal parameters. The experimental transition states for this compound are unknown because it has not yet been studied experimentally. Theoretical studies have shown that 2-(piperidin-1-yl)quinoxaline can be formed from a variety of pathways involving the following steps: hydrolysis of 2-(pyrrolidin-1-yl)quinoxaline, reductive amination of pyrrolidine with nitroethane, and reductive amination

1-Chloro-4-(phenylethynyl)benzene is a chlorinating agent that can activate terminal alkynes and halides. It is used to synthesize hydrocarbon solvents and as a reagent for the preparation of other organic compounds. The mechanism for chlorination is believed to be initiated by thermal decomposition, which produces chlorine radicals that react with alkynes and halides to produce alkyl chlorides. 1-Chloro-4-(phenylethynyl)benzene has been shown to be effective in the synthesis of amines, diketones, imidazoles, and fluorinated derivatives.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4-BOC-Piperazine-1-carbonyl chloride

5-Cyclobutyl-1H-1,2,4-triazol-3-amine

Versatile small molecule scaffold

Versatile small molecule scaffold

Please enquire for more information about H-His-Gly-Gly-OH trifluroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Versatile small molecule scaffold

Versatile small molecule scaffold

Methyl 2-formyl-3-hydroxybenzoate is a formylating agent that reacts with the hydroxyl group of benzene to form a methyl ester. It has been used in the production of polyphosphoric acid, and is also used in the synthesis of salicylic acid and other organic compounds. Methyl 2-formyl-3-hydroxybenzoate reacts with hexamethylenetetramine to produce hexamethylenetricarboxylic acid, which can be reacted with an alcohol to produce an ester. This reagent has been shown to have antifungal activity against Rhizoglyphus sp.

Versatile small molecule scaffold

Versatile small molecule scaffold

(2-Bromoethyl)oxirane is an industrial chemical that is a reactive, hydroxylated amine. It is used for the synthesis of pharmaceuticals and other organic compounds. (2-Bromoethyl)oxirane has been shown to induce cancer in animals, and it has also been shown to be carcinogenic in humans. The reaction with hydroxyl groups on proteins leads to the formation of reactive oxygen species that can cause damage to DNA. This chemical may also react with dopamine, which may contribute to degenerative diseases such as Parkinson's disease.

Versatile small molecule scaffold

1-(4-Iodophenyl)pyrrole (1-IP) is a bromoarene that can be biodegraded. It has been shown to react with nitroarenes, amines, and chlorine. 1-IP is thermally stable and can be used as a catalyst for reactions involving gaseous substrates. It has been shown to catalyze the synthesis of chlorides from choline and fluorine at room temperature. This reaction also produces large quantities of hydrogen chloride gas, which may pose safety hazards if not handled properly. 1-IP is reusable and has a high yield in the synthesis of chlorides.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Methyl 4-chloro-7-methoxyquinoline-6-carboxylate

3-(Ethylamino)phenol is a phenolic compound that has low detection limits. It can be detected in the presence of other aminophenols, polyester polymers, and acrylates. 3-(Ethylamino)phenol has been used as a fluorophore for acrylate-based polymers and as an antifungal agent with sulfide to inhibit the growth of fungi. This compound also shows red shift under uv absorption or fluorescence spectroscopy, which is due to the electron withdrawing effect of the ethylamino group.

Versatile small molecule scaffold

Versatile small molecule scaffold

6-(Morpholin-4-yl)nicotinaldehyde

Versatile small molecule scaffold

5-Isopropyl-1H-indole-2,3-dione

Versatile small molecule scaffold

Versatile small molecule scaffold

N-(1,3-Benzodioxol-5-ylmethyl)-3-nitroaniline

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

N-(Propan-2-yl)benzenecarbonimidoyl chloride (PCI) is a synthetic, water-soluble drug that is used to treat anaerobic infections. PCI binds to the imidoyl group of bacterial enzymes, such as penicillinase and beta-lactamase, and inhibits their activity. It has been shown that PCI has an affinity for copper ions in the crystallographic analysis. This affinity can be optimized by changing the substituents on the phenyl ring to increase affinity for copper ions. The oxadiazoles and hydroxyalkyl groups are also being considered for optimization of this compound. PCI has been shown to inhibit the growth of various bacteria in screening tests with a shift in its absorption spectrum.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1,3-Benzothiazole-5-carbonitrile

Versatile small molecule scaffold

3-Bromo-4-iodoanisole is a labile biomolecule that belongs to the class of unsymmetrical, pharmacophore ligands. It can be used as a receptor α antagonist and has been shown to inhibit proliferation of human breast cancer cells in vitro. 3-Bromo-4-iodoanisole binds to the proliferator-activated receptor γ (PPARγ) and blocks its interaction with ligand. PPARγ is involved in the regulation of cell differentiation and proliferation, lipid metabolism, and inflammation. The compound also inhibits the production of vascular endothelial growth factor (VEGF), which is a protein that stimulates blood vessel formation. This drug also interacts with biphenyls, which are compounds that have been reported to cause cancer in animals.

1-(3-Sulfopropyl)pyridinium inner salt (1SP) is a molecule that has been shown to bind to DNA. It is a potential drug target for the treatment of cancer, as it can cause cell lysis. 1SP binds to dsDNA and prevents the formation of stable base pairs, which leads to the lysis of cells. 1SP also has an effector protein activity that stimulates colony-stimulating factor production and induces apoptosis in human cells. This molecule has been shown to be effective against antimicrobial resistance bacteria such as methicillin resistant Staphylococcus aureus (MRSA). 1SP is capable of lysing bacterial cells in a process identical to that seen with mammalian cells. The mechanism by which this occurs is not yet clear but may involve surface methodology or sample preparation, both factors that have yet to be determined.

5-Chloro-3-(difluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine

Versatile small molecule scaffold

Versatile small molecule scaffold

3-(1-Methyl-3-piperidinyl)propanoic acid hydrochloride is a ligand that binds to the nicotinic acetylcholine receptor. It has been shown to be an inhibitor of the antibody response in rats. 3-(1-Methyl-3-piperidinyl)propanoic acid hydrochloride has also been shown to inhibit activation of ion channels, which may be due to its ability to bind to the ligand binding site and inhibit the binding of endogenous ligands such as acetylcholine. This ligand can be used in cell biology research, pharmacology, and as a research tool for protein interactions.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

N-[(3S)-(Piperidin-3-yl)]cyclopropanecarboxamide hydrochloride

(S)-1,4-Benzodioxane-2-carboxylic acid

4-Amino-1,1-dioxidotetrahydro-2H-thiopyran-4-carboxylic acid, N-BOC protected

Versatile small molecule scaffold

6-Hydroxypyridazine-3-carboxaldehyde is a monohydrate that has three hydrogen bonds and is planar. It is a chain with a pyridazine.

Methyl 4-iodo-1H-pyrrole-2-carboxylate

Versatile small molecule scaffold