Composés apparentés aux enzymes, aux peptides et aux protéines

Please enquire for more information about Big Endothelin-1 fragment (22-38) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Morantel citrate is a drug that belongs to the class of anthelmintics. It works by inhibiting the membrane system in nematodes, which leads to paralysis and death. Morantel citrate has been shown to be effective against Ostertagia ostertagi, Ancylostoma caninum, and Uncinaria stenocephala. Morantel citrate is not active against nematode species that are resistant to anthelmintics (e.g., Ascaris suum). The oral dose of morantel citrate for cattle is 0.5-1 mg/kg and for sheep 1-2 mg/kg body weight. This drug is poorly absorbed from the gastrointestinal tract and only about 10% of the dose reaches systemic circulation. Morantel citrate is metabolized in the liver by cytochrome P450 enzymes and excreted in urine as metabolites or unchanged drug.

Please enquire for more information about N-alpha-Acetyl-L-lysine 7-amido-4-methylcoumarin acetate salt hemihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (Asp56)-pTH (1-84) (rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Orexin A (human) TFA is a high quality reagent that can be used as an intermediate in the synthesis of complex compounds, useful for research and development. It has many potential uses, including as a fine chemical, speciality chemical and reaction component. Orexin A (human) TFA is a versatile building block with many applications, such as being a useful scaffold or building block in reactions where it can be used in the synthesis of other compounds. It is also a valuable research chemical that can be used to study orexin receptors and their ligands.

Please enquire for more information about Tyr-alpha-CGRP (23-37) (mouse, rat) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Trifluoroacetate salt

Resveratrol is a natural phenylpropanoid of the family of stilbenoids and is present in red wines and certain foods. Resveratrol has been deeply studied for its antioxidant, anti-inflammatory and antimicrobial properties. In Vero cells, resveratrol at 50 ÎŒM has shown to have the ability to inhibit SARS-CoV-2 replication by 98% when added after infection. Featured reference paper: Rossi et al, 2021; Yang et al, 2021.

Please enquire for more information about Band 3 Protein (824-829) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about RFRP-3 (rat) including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-HT2A serotonin receptor antagonist

4-Butanoyloxybenzenediazonium Tetrafluoroborate is a fluoroborate that has discriminative properties. It is used in the determination of butyrylcholinesterase activity and to study the environment of the active site. 4-Butanoyloxybenzenediazonium Tetrafluoroborate reacts with propidium to form an affinity label, which can be detected by measuring fluorescence intensity. The binding site on acetylcholinesterase is positioned at the side of the enzyme opposite to the substrate (a quaternary ammonium salt). Inactivation occurs when pH levels are too high or too low. This inhibitor also binds to a region on the enzyme other than its active site, which prevents acetylcholine from binding and hydrolyzing choline esters.

Potassium (bromomethyl)trifluoroborate is a boronic acid compound that has been used as an amide coupling agent. It is a potassium salt of the trifluoroborate ion, which can be produced by reacting methyltriphenylborane with potassium bromide. Potassium (bromomethyl)trifluoroborate is used in cross-coupling reactions to form amides from primary amines and aryl chlorides. The functional groups on the molecule include carboxylic acid, alcohol, ester, ether, and chloride. Potassium (bromomethyl)trifluoroborate can be synthesized from the reaction of kallikrein with chlorides or amines.

Please enquire for more information about VIP sulfoxide (human, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Caffeine citrate is a low-dose caffeine product that has been shown to increase locomotor activity in rats. Caffeine citrate is an ester of caffeine and citric acid. It inhibits the enzyme that breaks down acetylcholine, which may lead to an increase in brain functions. Caffeine citrate is used as a treatment for apnea in pediatric patients, and it has also been shown to prevent bacterial translocation and reduce liver impairment caused by certain drugs. The therapeutic effect of caffeine citrate may be due to its ability to inhibit mitochondrial membrane potential, or its effects on basic proteins such as sodium citrate, or both.

Erythromycinacistrate is a macrolide antibiotic, which is derived from the bacterium *Saccharopolyspora erythraea*. Its mode of action involves binding to the 50S ribosomal subunit of susceptible bacteria, thereby inhibiting protein synthesis. This action effectively halts bacterial growth and replication, making it particularly effective against a wide range of Gram-positive and some Gram-negative bacteria. The primary uses and applications of Erythromycinacistrate involve the treatment of various bacterial infections such as respiratory tract infections, skin infections, and sexually transmitted infections, including those caused by *Mycoplasma* and *Chlamydia* species. Due to its mechanism of disrupting bacterial protein synthesis, it is often employed in clinical settings where alternative antibiotics are ineffective or contraindicated. Understanding its molecular interactions and synthesis pathways can provide insights into antibiotic resistance mechanisms and aid in the development of new antibacterial strategies.

Please enquire for more information about Acetyl-ACTH (4-24) (human, bovine, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Benzhydrylpiperazine hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page