Lignanes

Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.

Schisanhenol protects heart mitochondria, has antioxidative effects on LDL, and prevents apoptosis by inhibiting ROS.

Ether alcohol phenol

Polyphenol

Syringaresinol-di-O-glucoside is a lignan-derived glucoside, which is a naturally occurring compound found predominantly in the Syringa plant, part of the Oleaceae family. This compound is classified as a plant lignan glycoside, which is obtained through extraction from natural botanical sources, specifically those of the Syringa genus. Its mode of action primarily involves antioxidant activity, where it scours and neutralizes free radicals, protecting cellular structures from oxidative stress. This mechanism is vital in mitigating the damage caused by reactive oxygen species within biological systems. The primary applications and uses of Syringaresinol-di-O-glucoside are found within scientific research, particularly in studies focusing on pharmacology and biochemistry, where its effects on health and cellular aging processes are investigated. Additionally, the compound has been studied for its potential therapeutic benefits, including anti-inflammatory and chemopreventive properties, making it of interest in developing treatments for various degenerative diseases. Researchers analyze its interaction at the molecular level to explore its efficacy as a lead compound in the development of new pharmaceutical drugs that target oxidative stress-related pathways.

Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.