Sucres du squelette et nucléobases

Please enquire for more information about 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-phenylpurine including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Amino-2-iodopurine is a purine derivative that is used to study hypoxanthines. It can be converted to 2-chloroadenine, which has been shown to cause damage to cells in tissue culture. 6-Amino-2-iodopurine has also been shown to cause sarcomatous transformation of skin cells and the formation of 2-chloroadenosine and 2-aminoadenosine. These compounds are toxic and have been found in damaged DNA. 6-Amino-2-iodopurine also has substituents on the purines, which are damaged when they react with DNA.

Applications 6-Amino-5-nitrouracil (cas# 3346-22-3) is a compound useful in organic synthesis. References Graves, A., et al.: J. Mol. Biol., 377, 914 (2008),

Applications Used in the preparation of pyrrolotriazines.

6-Amino-1-benzyluracil is a triethyl orthoformate that reacts with an aldehyde to form an imine. This reaction is known as alkylation. The imine reacts with benzamidine to form an anticancer drug called lumazine, which has been shown to be effective against cancer cells. 6-Amino-1-benzyluracil had low solubility in water and was therefore refluxed with ethyl acetoacetate and elemental acetoacetate. 6-Amino-1-benzyluracil is insoluble in the organic phase and can be removed by filtration.

2'-Deoxy-5-fluoro-5'-o-[hydroxy(tetradecyloxy)phosphoryl]uridine is a pyrimidine nucleoside that is the active metabolite of 5-fluorouracil. It is an anticancer agent that inhibits tumor cells by blocking their ability to synthesize DNA. 2'-Deoxy-5-fluoro-5'-o-[hydroxy(tetradecyloxy)phosphoryl]uridine has been shown to be safe and effective in clinical trials in mice, but it has not yet been tested in humans. This drug may cause nausea and vomiting when administered intraperitoneally, which may limit its use as an anticancer agent.

Please enquire for more information about 1-[6-(Diethoxyphosphinyl)-2-O-methyl-beta-D-ribo-hexofuranosyl]uracil including the price, delivery time and more detailed product information at the technical inquiry form on this page

2’-C-Methyl-5-fluorouridine is a fine chemical that is used as a versatile building block for the synthesis of various complex compounds. It is also used as a reaction component in the synthesis of research chemicals and speciality chemicals. 2’-C-Methyl-5-fluorouridine is an important intermediate in organic chemistry and has many applications, such as being a reaction component in the synthesis of pharmaceuticals, agrochemicals, dyes, and perfumes.

Adenine phosphate is a molecule that acts as a regulator of endogenous adenosine. It has been shown to inhibit the growth of skin cells in tissue culture and to be effective against influenza virus and other viruses when used in combination with pyridoxine hydrochloride. The molecular weight of adenine phosphate is 314.2 g/mol, corresponding to two nitrogen atoms and four phosphorus atoms. Adenine phosphate is an oxidized form of adenosine triphosphate (ATP) with one phosphate group removed from the molecule. This irreversible oxidation occurs when ATP is exposed to the environment, for example, during tissue culture or viral infection. The effective dose for treating cancer has not yet been determined; however, doses of up to 5 mg/kg are not toxic to mice.

Please enquire for more information about 3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Purine nucleobase; component of nucleic acids and coenzymes