Nucléosides

8-Chloroadenosine-5'-monophosphate triethylammonium is a novel phosphoramidite that is used in the synthesis of DNA. 8-Chloroadenosine-5'-monophosphate triethylammonium has been shown to activate antiviral and anticancer drugs with high specificity. It is also used as a reagent for the synthesis of deoxyribonucleosides and nucleosides. 8-Chloroadenosine-5'-monophosphate triethylammonium has high purity and can be used in the synthesis of DNA, RNA, and other nucleosides.

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4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine is a novel nucleoside analogue that has high purity and high quality. It is an activator of DNA synthesis, diphosphate and monophosphate of deoxyribonucleosides, ribonucleosides and analogues. 4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine has been shown to have antiviral activities against herpes simplex virus type 1 (HSV1) in cell culture.

2'-Deoxy-5-hydroxyuridine is a hydrated form of uracil that is used in the synthesis of nucleic acids. It is also a substrate for DNA polymerases and has been shown to inhibit the replication of herpes simplex virus. 2'-Deoxy-5-hydroxyuridine has been shown to have biological properties, such as inhibition of radiation-induced transformation, inhibition of cancer cell growth, and antiviral activity. The mechanism by which 2'-deoxy-5-hydroxyuridine inhibits the replication of herpes simplex virus is unclear but may be due to its ability to inhibit cellular metabolism.

N2-Acetyl-5'-O-DMT-guanosine is a novel anticancer nucleoside that has been synthesized to mimic the natural nucleotides found in DNA. It is phosphorylated to N2-acetyl-5'-O-DMT-guanosine monophosphate, which can be converted back to the active form of N2-acetyl-5'-O-DMT guanosine by phosphatases. This agent activates DNA synthesis and inhibits viral replication, including HIV and herpes simplex virus. The antiviral activity is due to its inhibition of viral DNA polymerase and diphosphate kinase.

2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine is a modified nucleoside that has antiviral, anticancer and antimalarial activities. This compound has been synthesized as a monophosphate derivative of the natural nucleoside uridine. It is an activator of DNA polymerase, which helps to synthesize DNA in cells. 2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine also has anticancer activity due to its ability to inhibit the replication of the human tumor virus KSHV.

3'-O-Benzoyl-2'-deoxy-N2-isobutyrylguanosine is a new antiviral nucleoside, which has been synthesized by reacting benzoyl chloride with 2'-deoxy-N2-isobutyrylguanosine monophosphate. It is also a novel DNA and RNA phosphoramidite monomer that can be used for the synthesis of oligonucleotides and oligoribonucleotides. 3'-O-Benzoyl-2'-deoxy-N2-isobutyrylguanosine is an activator of HIV reverse transcriptase, which leads to inhibition of viral replication.

N4-Acetyl-3'-deoxy-3'-C-methylcytidine is a novel antiviral drug that is modified from cytidine. It is an activator of the monophosphate pathway of DNA synthesis, which causes the incorporation of N4-acetyl-3'-deoxy-3'-C-methylcytidine into ribonucleosides and deoxyribonucleosides. This compound has been shown to be active against a variety of cancers, including leukemia, colon cancer, breast cancer, and prostate cancer.

6-Methylthiopurine ribonucleotide is an inhibitor that belongs to the group of analogs of betamethasone. It has been shown to have anti-cancer properties and can induce apoptosis in cancer cells. This compound has also been studied for its potential use in treating urinary tract infections, as it has been shown to inhibit the growth of bacteria such as chlorhexidine-resistant strains. Additionally, 6-Methylthiopurine ribonucleotide has been found to be a potent inhibitor of human kinase and may have therapeutic potential for a variety of diseases. This compound has also been investigated as an inhibitor of tolvaptan, which is used to treat conditions such as hyponatremia. Overall, 6-Methylthiopurine ribonucleotide shows promising potential for the treatment of various diseases and conditions.

5-Fluoro-4’-C-methyluridine is a novel antiviral agent that is structurally related to the nucleoside analogue cytidine. It has been shown to be an activator of DNA polymerase, which may contribute to its antiviral activity. 5-Fluoro-4’-C-methyluridine has been shown to inhibit the growth of cancer cells by modifying the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). 5-Fluoro-4’-C-methyluridine has also been shown to have anticancer effects, as it inhibits cell proliferation and induces apoptosis.

N6,5'-O-Dibenzoyl-2'-deoxy-adenosine is a monophosphate nucleoside that is used in the synthesis of DNA. It is synthesized from 2'-deoxyadenosine, which is an antiviral agent against influenza virus and anticancer agent. N6,5'-O-Dibenzoyl-2'-deoxy-adenosine has been shown to be a potent activator of the polymerase chain reaction with high purity and novel properties.

2'-C-Methyl-6-S-methyl-6-thioinosine is a modified nucleoside that can be used as an antiviral and anticancer agent. It has been shown to activate the immune system by inducing cytokine production, which leads to increased cytotoxicity against tumor cells. 2'-C-Methyl-6-S-methyl-6-thioinosine has also been shown to inhibit DNA synthesis and induce apoptosis in cancer cells. This product is of high purity and quality, with a CAS number of 172722-76-8.

5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite is a nucleoside monophosphate, which is used as a synthetic building block in DNA and RNA synthesis. 5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite has shown anticancer activity, which may be due to its ability to inhibit the activation of oncogenes by acting as an antagonist at the cell surface. This agent also inhibits viral replication and is active against HIV, herpes simplex virus type 1, and varicella zoster virus.

6-O-Methyl-2'-deoxyinosine is a modified nucleoside that inhibits the synthesis of DNA and RNA. It is also an anticancer agent, inhibiting the growth of tumor cells by arresting the cell cycle at the G1 phase. 6-O-Methyl-2'-deoxyinosine is a phosphoramidite for use in solid phase synthesis of oligodeoxynucleotides (ODN). This product has high purity, good quality, novel structures and excellent stability. 6-O-Methyl-2'-deoxyinosine can be used to inhibit viral replication by preventing viral DNA from being replicated into double stranded DNA. The antiviral activity of 6-O-methyl 2'-deoxyinosine against HIV has been demonstrated in vitro and in vivo using monophosphate forms.

5’-O-(4-Cyanobenzyl)-2’,3’-di-O-isopropylideneadenosine is a monophosphate nucleoside. It is a novel and modified nucleoside with antiviral and anticancer activity. 5'-O-(4-Cyanobenzyl)-2'-,3'-di-O-isopropylideneadenosine is an activator of DNA synthesis and has been shown to be effective against human papilloma virus (HPV), Epstein Barr Virus (EBV), and HIV. This compound also has high purity, CAS No. 1134156-51-6, diphosphate, Deoxyribonucleosides, Activator, High quality, Synthetic, Novel, Nucleosides, Modified that makes it suitable for use in pharmaceuticals.

5'-O-DMT-2'-O-triisopropylsilyloxymethyl-N2-methylguanosine 3'-CE phosphoramidite is a novel monophosphate nucleotide analog of guanosine, which has been modified to include an additional methyl group on the 2' position. It exhibits antiviral activity and is a potent activator of RNA polymerase II, with a Km of ∼0.05 μM. 5'-O-DMT-2'-O-triisopropylsilyloxymethyl-N2-methylguanosine 3'-CE phosphoramidite is used in the synthesis of ribonucleosides and deoxyribonucleosides for DNA and RNA experiments. The compound has also been shown to be active against some cancers, such as leukemia, breast cancer, prostate cancer, and colon cancer. 5'-O-DMT-2'-O-

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9-(b-D-Ribofuranosyl)purine (9-BRP) is a purine nucleoside that is used in the synthesis of dyes. It has been shown to be an effective inhibitor of the enzyme phosphodiesterase 3B, which breaks down cyclic adenosine monophosphate (cAMP), and therefore can prevent kidney fibrosis. 9-BRP has also been shown to inhibit the synthesis of collagen by binding to cAMP. In addition, 9-BRP binds to DNA and forms hydrogen bonds with nitrogen atoms on the phosphate groups in DNA. This interaction prevents the formation of hydrogen bonds between water molecules in water vapor and phosphate groups, thus slowing down their rate of dissociation from each other. 9-BRP also has a high affinity for Toll-like receptor 4 (TLR4), which is involved in the inflammatory response, making it an ideal therapeutic candidate for treating inflammation and renal fibrosis.

L-Thymidine-5'-triphosphate sodium salt (L-TTP) is a modified nucleoside that is used as an anticancer agent. L-TTP is phosphorylated by ATP to form L-thymidine 5'-monophosphate (L-TMP). It also inhibits viral replication by inhibiting the synthesis of DNA and RNA, leading to cell death. L-TTP has been shown to be active against herpes simplex virus type 1, herpes simplex virus type 2, and cytomegalovirus.