Bêta-bloquants
Les bêta-bloquants, également appelés agents bloquants des récepteurs bêta-adrénergiques, sont des composés qui bloquent l'action de l'épinéphrine (adrénaline) sur les récepteurs bêta, ralentissant ainsi la fréquence cardiaque et réduisant la pression artérielle. Ils sont souvent utilisés pour traiter des affections telles que l'hypertension, les arythmies et l'insuffisance cardiaque. Chez CymitQuimica, nous proposons une variété de bêta-bloquants à des fins de recherche en études cardiovasculaires et cliniques.
Sous-catégories appartenant à la catégorie "Bêta-bloquants"
Produits appartenant à la catégorie "Bêta-bloquants"
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Ranolazine-d8 Dihydrochloride
CAS :Produit contrôléFormule :C24H25D8N3O4• 2(HCl)Couleur et forme :NeatMasse moléculaire :435.59 + 2(36.46)Carvedilol
CAS :Produit contrôléApplications Carvedilol is a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990); Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996);Formule :C24H26N2O4Couleur et forme :WhiteMasse moléculaire :406.47Oxprenolol
CAS :Formule :C15H23NO3Couleur et forme :White To Off-White SolidMasse moléculaire :265.35Nebivolol hydrochloride
CAS :Nebivolol hydrochloride is a beta-1 blocker and vasodilator treating hypertension and heart failure in the elderly.Formule :C22H25F2NO4·HClDegré de pureté :100% - 99.77%Couleur et forme :White To Off-White PowderMasse moléculaire :441.9Ref: TM-T0154
10mg50,00€25mg69,00€50mg96,00€100mg163,00€200mg268,00€500mg464,00€1mL*10mM (DMSO)46,00€Desacetyl Diltiazem
CAS :Impurity Diltiazem EP Impurity F Applications Desacetyl Diltiazem (Diltiazem EP Impurity F) is a metabolite of Diltiazem (D460620). References Shallcross, H., et al.: Br. Med. J., 295, 1236 (1987), Yeung, P.K.F., et al.: Drug Metab. Dispos., 18, 1055 (1990), Cashman, J.R., et al.: J. Med. Chem., 34,2049 (1991),Formule :C20H24N2O3SCouleur et forme :White To BrownMasse moléculaire :372.48N-Nitroso Labetalol (Mixture of Diastereomers)
CAS :Formule :C19H23N3O4Couleur et forme :Off-White SolidMasse moléculaire :357.415-Aminoimidazole-4-carboxamide-1-Beta-D-ribofuranoside
CAS :Applications AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective. References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)Formule :C9H14N4O5Couleur et forme :NeatMasse moléculaire :258.23N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine Methyl Ester Hydrochloride
CAS :Formule :C20H22N2O2·ClHrac-Nebivolol-d4 HCl (Mixture of Diastereomers)
CAS :Formule :C22H21D4F2NO4·HClCouleur et forme :Off-White SolidMasse moléculaire :409.47 36.464-(2,3-Epoxypropoxy)carbazole
CAS :Produit contrôléImpurity Carvedilol EP Impurity D; Carvedilol USP-D Applications 4-(2,3-Epoxypropoxy)carbazole (Carvedilol EP Impurity D; Carvedilol USP-D) is an intermediate in the synthesis of Carvedilol (C184625).Formule :C15H13NO2Couleur et forme :Beige SolidMasse moléculaire :239.272-(Ethylamino)-1-(3-hydroxyphenyl)ethanone Hydrochloride (Etilefrone Hydrochloride)
CAS :Couleur et forme :Neat(2RS)-1-[4-[(EZ)-2-Methoxyethenyl]-phenoxy]-3-[(1-methylethyl)amino]propan-2-ol
CAS :Formule :C15H23NO3Spironolactone
CAS :Produit contrôléFormule :C24H32O4SCouleur et forme :NeatMasse moléculaire :416.57Diethyl 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
CAS :Formule :C19H22N2O6Nebivolol Impurity (1-(3,4-dihydro-2H-chromen-2-yl)-2-(methylamino)ethanol)
Formule :C12H17NO2Masse moléculaire :207.27(1R,4R)-1,2,3,4-Tetrahydro-4,6-dihydroxy-1-(3-hydroxyphenyl)-2-methylisoquinoline
CAS :Formule :C16H17NO37-Hydroxy Coumarin-13C6 Sulfate Potassium Salt
CAS :Produit contrôléFormule :C313C6H5KO6SCouleur et forme :NeatMasse moléculaire :286.253-Ethyl 5-Methyl 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate Fumarate
CAS :Formule :C20H23ClN2O5·C4H4O4Carvedilol Bis-carbazole
CAS :Produit contrôléImpurity Carvedilol EP Impurity B; Carvedilol Impurity B; Carvedilol USP B Applications Carvedilol Bis-carbazole (Carvedilol EP Impurity B; Carvedilol Impurity B; Carvedilol USP B) is an impurity from the process of Carvedilol (C184625).Formule :C39H39N3O6Couleur et forme :Off-White To Light BeigeMasse moléculaire :645.746,7,8,9-Tetrahydro Carvedilol
CAS :Produit contrôléApplications Carvedilol (C184625) derivative. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageFormule :C24H30N2O4Couleur et forme :NeatMasse moléculaire :410.51(2RS)-1-[4-(2-Butoxyethyl)phenoxy]-3-[(1-methylethyl)amino]propan-2-ol Hydrochloride
CAS :Formule :C18H31NO3·ClH1-(3-Hydroxyphenyl)-2-(methylamino)ethanone Hydrochloride (Phenylephrone Hydrochloride)
CAS :Formule :C9H11NO2·ClHCarvedilol Bisalkylpyrocatechol Derivative
Formule :C40H42N4O6Couleur et forme :White To Off-White SolidMasse moléculaire :674.80(RS)-1-(4-Hydroxymethylphenoxy)-3-isopropylaminopropan-2-ol
CAS :Produit contrôléFormule :C13H21NO3Couleur et forme :NeatMasse moléculaire :239.31(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]propanoic Acid
CAS :Produit contrôléFormule :C15H21NO4Couleur et forme :NeatMasse moléculaire :279.33Metoprolol tartrate
CAS :Metoprolol Tartrate is a blocker of the cardioselective β-adrenergic receptor.Formule :C15H25NO3C4H6O6Degré de pureté :99.72% - 99.93%Couleur et forme :White To Off-White / PowderMasse moléculaire :684.81L-Nebivolol (RS,SS) HCl
CAS :Formule :C22H25F2NO4·HClCouleur et forme :White To Off-White SolidMasse moléculaire :405.44 36.46Cilazapril Monohydrate
CAS :Produit contrôléFormule :C22H31N3O5·H2OCouleur et forme :NeatMasse moléculaire :417.503-Hydroxy Carvedilol
CAS :Produit contrôléApplications A vascularly inactive metabolite of Carvedilol (C184625). A novel antihypertensive agent, is a potent antioxidant. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Rapola, J., et al.: Lancet, 349, 1715 (1997), Gao, F., et al.: Eur. J. Pharmacol., 406, 109 (2000),Formule :C24H26N2O5Couleur et forme :NeatMasse moléculaire :422.47Acebutolol EP Impurity C (Acebutolol USP Related Compound A)
CAS :Produit contrôléFormule :C12H15NO3Couleur et forme :NeatMasse moléculaire :221.25(2S,3aS,6aS)-Octahydrocyclopenta[b]pyrrole-2-carboxylic Acid Phenylmethyl Ester Hydrochloride
CAS :Formule :C15H19NO2·ClH9,11beta-Epoxy-17,21-dihydroxy-16beta-methyl-9beta-pregna-1,4-diene-3,20-dione
CAS :Formule :C22H28O5Methyl [1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate (Indomethacin Methyl Ester)
CAS :Formule :C20H18ClNO4myo-Inositol-d6 Trispyrophosphate Hexasodium Salt
CAS :Produit contrôléApplications Labelled myo-Inositol Trispyrophosphate hexasodium (I666020). A novel membrane-permeant allosteric effector of hemoglobin (Hb), enhances the regulated oxygen release capacity of red blood cells, thus counteracting the effects of hypoxia in diseases such as cancer and cardiovascular ailments. References Duarte,C.D. et al.: Chembiochem., 11, 2543 (2010); Biolo, A. et al.: Proc. Nat. Acad. Sci. U.S.A., 106, 1926 (2009);Formule :C6D6Na6O21P6Couleur et forme :White To Light BeigeMasse moléculaire :743.92Felodipine
CAS :Applications A dihydropyridine calcium channel blocker. References Berntsson, P.B., et al.: Acta Pharm. Suec., 18, 221 (1981), Kratochwil, N., et al.: Biochem. Pharmacol., 64, 1355 (2002), O'Brien, S., et al.: J. Med. Chem., 48, 1287 (2005), Castilho, M., et al.: Bioorg. Med. Chem., 14, 516 (2006),Formule :C18H19Cl2NO4Couleur et forme :Off WhiteMasse moléculaire :384.25Carvedilol Related Compound C (1-(9H-Carbazol-4-yloxy)-3-(benzyl(2-(2-methoxyphenoxy)ethyl)amino)propan-2-ol)
CAS :Aromatic or modified aromatic drugs with nitrogen hetero-atom(s) only, not elsewhere specified or includedFormule :C31H32N2O4Couleur et forme :Off-White PowderMasse moléculaire :496.23621Pentoxifylline
CAS :Produit contrôléFormule :C13H18N4O3Couleur et forme :NeatMasse moléculaire :278.312-[[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]methyl]oxirane
CAS :2-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]methyloxirane is a metabolite of the drug product 2-[[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]methyl]oxirane. It is an impurity in the drug product, which is a pharmaceutical intermediate that has been shown to have pharmacological properties. The CAS number for this compound is 63659-17-6 and it has been assigned the Chemical Abstracts Service (CAS) number of 63659-17-6. This compound has been characterized using HPLC and GC/MS methods.Formule :C15H20O3Degré de pureté :Min. 95%Masse moléculaire :248.32 g/mol(3RS,5RS,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic Acid Calcium Salt
Formule :C22H27FN3O6S·CaCouleur et forme :NeatBis(2-methoxyethyl) 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
CAS :Produit contrôléFormule :C21H26N2O8Couleur et forme :NeatMasse moléculaire :434.443-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol
CAS :Produit contrôléImpurity Metoprolol EP Impurity D Applications 3-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol (Metoprolol EP Impurity D) is a new byproduct detected in Metoprolol tartrate. Metoprolol (M338790) impurity. References Erickson, M., et al.: J. Pharmac. Biomed. Anal., 13, 567 (1995),Formule :C12H18O4Couleur et forme :WhiteMasse moléculaire :226.27Propranolol Glucuronide Sodium Salt (Mixture of Diastereomers)
CAS :Formule :C22H28NO8·NaCouleur et forme :White To Off-White SolidMasse moléculaire :434.47 22.993-Hydroxy-4-morpholino-1,2,5-thiazole
CAS :Impurity Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D Applications 3-Hydroxy-4-morpholino-1,2,5-thiazole (Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D) is an intermediate for the preparation of Timolol. References Bodor, N., et al.: J. Med. Chem., 31, 100 (1988),Formule :C6H9N3O2SCouleur et forme :White To Off-WhiteMasse moléculaire :187.22N-[2-Hydroxy-3-[4-(2-isopropoxyethoxymethyl)phenoxy]propyl]formamide (N-Desisopropyl-N-formyl Bisoprolol)
CAS :Couleur et forme :Neat3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide
CAS :3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide is an impurity found in the drug product of 3'-acetyl-4'-(2,3-epoxypropoxy)butyranilide hydrochloride. It has a molecular weight of 268.9 and chemical formula C12H18O6N2. 3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide is a synthetic compound that can be used as an analytical reference material for HPLC standardization or as an impurity standard for synthesis.Formule :C15H19NO4Degré de pureté :Min. 95%Masse moléculaire :277.32 g/molMethyl 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (Candesartan Methyl Ester)
CAS :Produit contrôléFormule :C25H22N6O3Couleur et forme :NeatMasse moléculaire :454.49Fluvastatin-d7 Sodium Salt
CAS :Produit contrôléApplications Fluvastatin-d7 Sodium Salt is a labeled synthetic HMG-CoA reductase inhibitor. Antilipemic. References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991); Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992); Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993)Formule :C24H18D7FNNaO4Couleur et forme :NeatMasse moléculaire :440.49Benzthiazide
CAS :Produit contrôléFormule :C15H14ClN3O4S3Couleur et forme :NeatMasse moléculaire :431.94(+)-Noradrenaline Bitartrate
CAS :Formule :C8H11NO3·C4H6O6Couleur et forme :White To Off-WhiteMasse moléculaire :319.26N-(Imidazolidin-2-ylidene)-4,6-dimethoxy-2-methylpyrimidin-5-amine (4-Methoxymoxonidine)
CAS :Formule :C10H15N5O22-Chloro-6,7-dimethoxyquinazolin-4-amine
CAS :Produit contrôléFormule :C10H10ClN3O2Couleur et forme :NeatMasse moléculaire :239.66Cinchocaine Hydrochloride Imp. B (EP): 2-Hydroxyquinoline-4-
CAS :Produit contrôléFormule :C10H7NO3Couleur et forme :NeatMasse moléculaire :189.17Methyl 3-Aminobut-2-enoate
CAS :Produit contrôléFormule :C5H9NO2Couleur et forme :NeatMasse moléculaire :115.13Nadolol EP Impurity C (Mixture of Diastereomers)
Formule :C23H28O7Couleur et forme :Off-White SolidMasse moléculaire :416.471-(1-Naphthyloxy)-2,3-epoxypropane
CAS :Produit contrôléFormule :C13H12O2Couleur et forme :NeatMasse moléculaire :200.23(3RS)-N,N-Bis(1-methylethyl)-3-phenyl-3-(pyridin-2-yl)propan-1-amine Dihydrogen Phosphate
CAS :Formule :C20H28N2·H3O4P3-Ethyl 5-Methyl 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate Fumarate
CAS :Formule :C20H23ClN2O5·C4H4O42-[Hydroxy(4-phenylbutyl)phosphoryl]acetic Acid Disodium Salt
Formule :C12H15O4P·2NaCouleur et forme :NeatTerazosin EP Impurity M (Prazosin EP Impurity B)
CAS :Produit contrôléFormule :C14H14N2O4Couleur et forme :NeatMasse moléculaire :274.272'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid
CAS :Produit contrôléStability Hygroscopic Applications 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is a transformation product of Valsartan (V095750); a nonpeptide angiotensin II AT1-receptor antagonist and antihypertensive. 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is also referred to as Valsartan acid. References Noedler, K., et al.: Water Res., 47, 6650 (2013); Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993); Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)Formule :C14H10N4O2Couleur et forme :White To Off-WhiteMasse moléculaire :266.25Carvedilol Related Compound E (2-(2-Methoxyphenoxy)ethyl amine hydrochloride monohydrate)
CAS :Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen functionFormule :C9H13NO2Couleur et forme :Off-White PowderMasse moléculaire :167.09463Lacidipine
CAS :Produit contrôléApplications A dihydropyridine calcium channel blocker. Antihypertensive. References Safar, M., et al.: Clin. Pharmacol. Ther., 46, 94 (1989), Kharat, V.R., et al.: J. Pharm. Biomed. Anal., 28, 789 (2002), McCormack, A.J., et al.: Drugs, 63, 2327 (2003),Formule :C26H33NO6Couleur et forme :Light YellowMasse moléculaire :455.54(S)-Metoprolol-d7
CAS :Produit contrôléApplications Active enantiomer of Metoprolol, a β1 receptor blocker used as an antihypertensive. References Hritz, J., et al.: J. Med. Chem., 51, 7469 (2008), van Steeg, T., et al.: J. Pharm. Sci., 98, 3816 (2009), Zhang, Z., et al.: Anal. Biochem., 387, 171 (2009),Formule :C15H18D7NO3Couleur et forme :NeatMasse moléculaire :274.41Carteolol HCl EP Impurity E
CAS :Formule :C21H22N2O5Couleur et forme :White To Off-White SolidMasse moléculaire :382.422-Hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzoic Acid Hydrochloride
CAS :Couleur et forme :NeatNebivolol Related Compound 1 HCl (Mixture of (RR,SR) and (SS,RS) Isomer)
CAS :Formule :C22H25F2NO4·HClCouleur et forme :White To Off-White SolidMasse moléculaire :405.45 36.46Aprindine Hydrochloride
CAS :Applications Aprindine is a long-acting antiarrhythmic agent, effective when administered orally or intravenously in the treatment of ventricular arrhythmias of varying etiologies. References Danilo, P. Jr., et al.: Am. Heart. J., 97, 119 (1979); Atarashi, H., et al.: Circulation. J., 66, 553 (2002);Formule :C22H30N2·ClHCouleur et forme :NeatMasse moléculaire :358.952-Hydroxy Atorvastatin Dihydrate Monosodium Salt
CAS :Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),Formule :C33H38FN2NaO8Couleur et forme :NeatMasse moléculaire :632.652-[4-[(2RS)-2,3-Dihydroxypropoxy]phenyl]acetamide
CAS :Produit contrôléFormule :C11H15NO4Couleur et forme :NeatMasse moléculaire :225.244-(Hydroxyacetyl)morpholine
CAS :Produit contrôléFormule :C6H11NO3Couleur et forme :NeatMasse moléculaire :145.16
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