Modulateurs du GABA
Les modulateurs de GABA sont des composés qui influencent la fonction des récepteurs GABA (acide gamma-aminobutyrique), les principaux récepteurs inhibiteurs des neurotransmetteurs dans le système nerveux central. Ces modulateurs peuvent soit renforcer, soit inhiber l'activité GABAergique, affectant l'excitabilité neuronale et la transmission synaptique. Les modulateurs de GABA sont cruciaux dans le traitement et l'étude de divers troubles neurologiques et psychiatriques, y compris l'anxiété, l'épilepsie et l'insomnie. Chez CymitQuimica, nous proposons une large gamme de modulateurs de GABA pour soutenir vos recherches en neurosciences, pharmacologie et neurothérapeutique.
Produits appartenant à la catégorie "Modulateurs du GABA"
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Phenazepam-d5
CAS :Produit contrôléApplications A benzodiazepine drug, which is used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal and insomnia. It can be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety. References Ogiso, T., et al.: Chem. Pharm. Bull., 37, 446 (1989), Gu, Q., et al.: J. Med. Chem., 36, 1001 (1993), Bekhterev, V.N., et al.: Pharm. Chem. J., 42, 95 (2008),Formule :C152H4H6BrClN2OCouleur et forme :NeatMasse moléculaire :353.63N-Demethyl Olanzapine-d8
CAS :Produit contrôléApplications A labelled metabolite of Olanzapine.Formule :C162H8H10N4SCouleur et forme :NeatMasse moléculaire :306.46Delorazepam (100 ug/mL in Methanol)
CAS :Produit contrôléFormule :C15H10Cl2N2OCouleur et forme :Single SolutionMasse moléculaire :305.168-Fluoro-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid
CAS :Formule :C13H10FN3O3Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :275.23524-Boc-7-Bromo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS :Degré de pureté :97.0%Couleur et forme :SolidMasse moléculaire :327.221984863281251H-1,4-Benzodiazepine-2,5-dione, 3,4-dihydro-
CAS :Formule :C9H8N2O2Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :176.17202N-Desmethyl Clozapine-d8
CAS :Produit contrôléApplications A major labelled metabolite of clozapine. A potent and selective 5-HT2C serotonin receptor antogonist. References Kuoppamaki, M. et al.: Eur. J. Pharm. Mol. Pharm. Sect., 245, 179 (1993), Olessen, O.V., et al.: J. Chromatog., 622, 39 (1993), Pirmohamed, M., et al.: J. Pharmacol. Exp. Ther., 272, 984 (1995)Formule :C172H8H9ClN4Couleur et forme :Light YellowMasse moléculaire :320.85(S)-Methyl 3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate
CAS :Degré de pureté :97.0%Masse moléculaire :402.24798583984375Zopiclone N-Oxide
CAS :Impurity Zopiclone EP Impurity A Applications Eszopiclone impurity A. References Vire, J.C., et al.: Talanta, 40, 313 (1993), Sha, Yu., et al.: Molecules, 13, 1817 (2008),Formule :C17H17ClN6O4Couleur et forme :White To Light BrownMasse moléculaire :404.812-Propylglutaric Acid
CAS :Produit contrôléApplications A metabolite of Valproic Acid. References McLean, M.J., et al.: J. Pharmacol. Exp. Ther., 237, 1001 (1986), Lee, R.D., et al.: J. Pharm. Sci., 78, 667 (1989), Mergen, F., et al.: J. Pharm. Pharmacol., 43, 815, (1991)Formule :C8H14O4Couleur et forme :NeatMasse moléculaire :174.192-Propanone, 1-[4,5-dihydro-2-(4-methyl-1-piperazinyl)-4-thioxo-3H-1,5-benzodiazepin-3-ylidene]-, (1Z)-
CAS :Formule :C17H20N4OSDegré de pureté :97%Couleur et forme :SolidMasse moléculaire :328.43199-Amino-1,2,3,4-tetrahydro-1,4-benzodiazepin-5-one
CAS :Formule :C9H11N3ODegré de pureté :95%Couleur et forme :SolidMasse moléculaire :177.20311-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :190.201995849609383-Hydroxy Bromazepam 1.0 mg/mL in Methanol
CAS :Produit contrôléFormule :C14H10BrN3O2Couleur et forme :ColourlessMasse moléculaire :332.15Flumazenil (Ro 15-1788)
CAS :Formule :C15H14FN3O3Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :303.28836319999994Ref: IN-DA005JF1
1g300,00€5gÀ demander25gÀ demander50gÀ demander5mg44,00€10mg54,00€100mg82,00€250mg139,00€Allobarbital
CAS :Produit contrôléApplications Allobarbital is a barbiturate derivative that is primarily used as an anticonvulsant. Allobarbital also shows hypnotic activity and is used to boost the activity of analgesic drugs. Studies show that Allobarbital is an effective promoters of hepatocarcinogenesis. Allobarbital is a Controlled Substance. References Tateoka, Y. et al.: Yakug. Zas., 106, 504 (1986); Crawford, J.M. et al.: Neuropharmacology, 9, 31 (1970); Rice, J.M. et al.: Carcinogenesis, 15, 395 (1994);Formule :C10H12N2O3Couleur et forme :WhiteMasse moléculaire :208.214-Methyl-2,3,4,5-tetrahydro-1h-benzo[e][1,4]diazepine
CAS :Degré de pureté :95%Masse moléculaire :162.235992431640621'-Hydroxy Triazolam (1.0 mg/mL in DMSO)
CAS :Produit contrôléFormule :C17H12Cl2N4OCouleur et forme :Single SolutionMasse moléculaire :359.215H-1-Benzazepin-5-one, 7-chloro-1,2,3,4-tetrahydro-
CAS :Formule :C10H10ClNODegré de pureté :97%Couleur et forme :SolidMasse moléculaire :195.6455Zaleplon-D5
CAS :Produit contrôléApplications Selective non-benzodiazepine GABAA receptor agonist. References Allen, D., et al.: Eur. J. Clin. Pharmacol., 45, 313 (1993), Beer, B., et al.: J. Clin. Pharmacol., 34, 335 (1994), Rosen, A.S., et al.: Biopharm. Drug Dispos., 20, 171 (1999), Elie, R., et al.: J. Clin. Psychiatry, 60, 536 (1999), Heydorn, W.E., et al.: Expert Opin. Invest. Drugs, 9, 841 (2000)Formule :C172H5H10N5OCouleur et forme :Off White SolidMasse moléculaire :310.36Chlordiazepoxide-d5
CAS :Produit contrôléApplications Controlled substance (depressant). Anxiolytic. Prototype of the benzodiazepine anxiolytics. References MacDonald, A., et al.: Anal. Profiles Drug Subs., 1, 15 (1972), Greenblatt, D.J., et al.: Clin. Pharmacokinet., 3, 381 (1978),Formule :C162H5H9ClN3OCouleur et forme :NeatMasse moléculaire :304.797-methyl-5-phenyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one
CAS :Degré de pureté :95.0%Masse moléculaire :252.31700134277344Talbutal
CAS :Produit contrôléApplications A stuctural isomer of Butalbital (B690100). A short to intermediate-acting barbiturate that act as nonselective depressants of the central nervous system (CNS). Sedative, hypnotic. Controlled Substance. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Nielsen, C.J. et al.: Pharmacol., 26, 371 (1925); Lien, E.J. et al.: Acta Pharmac. Jug., 34, 123 (1984);Formule :C11H16N2O3Couleur et forme :NeatMasse moléculaire :224.26(4RS)-4-(2-Methylpropyl)pyrrolidin-2-one (4-Isobutylpyrrolidin-2-one; (RS)-Pregabalin Lactam)
CAS :Couleur et forme :Neat4-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione
CAS :Degré de pureté :95.0%Masse moléculaire :190.201995849609388-Amino-4-Boc-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS :Degré de pureté :97.0%Masse moléculaire :263.341003417968751,3-Dimethyl Barbituric Acid
CAS :Produit contrôléApplications 1,3-Dimethyl Barbituric Acid (Urapidil Impurity 4) is a derivative of Barbituric acid (B118650). All of the barbituric acid derivatives which have been reported to have pronounced hypnotic activity are disubstituted in the 5-position. References Gupta, K., et al.: Eur. J. Med. Chem., 17, 448 (1982), Weber, L., et al.: Curr. Med. Chem., 9, 2085 (2002), Skiles, J., et al.: Curr. Med. Chem., 11, 2911 (2004),Formule :C6H8N2O3Couleur et forme :NeatMasse moléculaire :156.14N-DESMETHYLCLOZAPINE
CAS :Formule :C17H17ClN4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :312.7967Clobazam-d5
CAS :Produit contrôléApplications Labelled Clobazam (C582500). Benzodiazepine psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant. Controlled substance (depressant). References Gastaut, H., et al.: Epilepsia, 20, 437 (1979), Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990), Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993),Formule :C16H8D5ClN2O2Couleur et forme :Off White PowderMasse moléculaire :305.77nor-Flurazepam
CAS :Produit contrôléImpurity Flurazepam USP Related Compound F Applications The major human metabolite of Flurazepam. Controlled substance.Flurazepam USP Related Compound F. References Ochs, H.R., et al.: Pharmacology, 36, 166 (1988); Capello, S., et al.: Drug Metab. Dispos., 18, 190 (1990);Formule :C15H10ClFN2OCouleur et forme :White To Off-WhiteMasse moléculaire :288.705-Allyl-6-imino-5-(1-methyl-2-pentynyl)hydrouracil-13C,15N2
Produit contrôléFormule :C12CH17NN2O2Couleur et forme :NeatMasse moléculaire :250.2710-Hydroxy-10,11-dihydrocarbamazepine
CAS :Produit contrôléFormule :C15H14N2O2Couleur et forme :NeatMasse moléculaire :254.28Rufinamide USP Related Compound B
CAS :Produit contrôléFormule :C11H9F2N3O2Couleur et forme :NeatMasse moléculaire :253.20Secobarbital
CAS :Produit contrôléApplications Barbiturates are being widely used as antiepileptics, hypnotics, and anesthetics.Controlled substance. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Inaba, T., et al.: Clin. Pharm. Ther., 20, 439 (1976), Sun, S., et al.: J. Pharm. Sci., 66, 477 (1977), Coudore, F., et al.: J .Anal. Toxicol., 17, 109 (1993), Ferslew, K., et al.: J. Forensic Sci., 40, 245 (1995),Formule :C12H18N2O3Couleur et forme :WhiteMasse moléculaire :238.282,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine
CAS :Degré de pureté :97.0%Couleur et forme :Solid, White to yellow/orange crystalline powderMasse moléculaire :148.20899963378906Diazepam-13C,d3
CAS :Produit contrôléApplications Labelled Diazepam, an anxiolytic; muscle relaxant (skeletal); anticonvulsant.Diazepam is a Controlled substance (depressant). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References MacDonald, A., et al.: Anal. Profiles Drug Subs., 1, 79 (1972), Mandelli, M., et al.: Clin. Pharmacokinet., 3, 72 (1978), Bertilsson, L., et al.: Pharmacol. Ther., 45, 85 (1990), Murray, J.B., et al.: J. Psychol., 124, 655 (1990), Pellock, J.M., et al.: Drug Saf., 27, 383 (2004),Formule :C1513CH10D3ClN2OCouleur et forme :NeatMasse moléculaire :288.7510H-Thieno[2,3-b][1,5]benzodiazepin-4-amine, 2-methyl-,monohydrochloride
CAS :Formule :C12H12ClN3SDegré de pureté :95%Couleur et forme :SolidMasse moléculaire :265.7618Pinazepam
CAS :Produit contrôléApplications Pinazepam is a is a benzodiazepine. Pinazepam possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Pinazepam is less toxic than Diazepam. This is a contolled substance (depressant). Anxiolytic. References Bertoncelli, V., et al.: Clin. Ter., 94, 641 (1980); Miyaguchi, H., et al.: Forensic Sci. Int., 157, 57 (2006), ElSohly, M., et al.: J. Anal. Toxicol., 32, 547 (2008), Vogliardi, S., et al.: Anal. Bioanal. Chem., 2011, 400, 51 (2011),Formule :C18H13ClN2OCouleur et forme :NeatMasse moléculaire :308.76Zolazepam Hydrochloride
CAS :Produit contrôléApplications A sedative and anesthetic agent. References Winters, W., et al.: Neuropharmacology, 11, 303 (1972), Genevois, J., et al.: Rec. Med. Vet.,164, 289 (1988),Formule :C15H15FN4O·ClHCouleur et forme :NeatMasse moléculaire :322.77Clozapine
CAS :This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formule :C18H19ClN4Couleur et forme :Crystalline powder, YellowMasse moléculaire :326.83
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