Système complémentaire
Le système du complément est une partie cruciale de la réponse immunitaire, composée d'une série de petites protéines qui améliorent la capacité des anticorps et des cellules phagocytaires à éliminer les agents pathogènes d'un organisme. Ces protéines travaillent ensemble pour opsoniser les agents pathogènes, induire des réponses inflammatoires et lyser directement les membranes des pathogènes, jouant un rôle vital dans l'immunité innée et la fonction immunitaire globale. Chez CymitQuimica, nous proposons des protéines du système du complément de haute qualité pour soutenir vos études immunologiques et recherches cliniques.
Produits appartenant à la catégorie "Système complémentaire"
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C5AR1 Protein, Mouse, Recombinant (MBP & His-Avi), Biotinylated
C5AR1 Protein, Mouse, Recombinant (MBP & His-Avi), Biotinylated is expressed in E. coli with N-MBP, C-6xHis-Avi. The accession number is P30993.Couleur et forme :Lyophilized PowderMasse moléculaire :52.8 kDa (Predicted)W-54011
CAS :W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).Formule :C30H37ClN2O2Degré de pureté :95.62%Couleur et forme :SolidMasse moléculaire :493.08Ref: TM-T17250
1mg85,00€5mg127,00€10mg187,00€25mg335,00€50mg518,00€100mg747,00€1mL*10mM (DMSO)165,00€C1s-IN-1 trihydrochloride
CAS :C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.Formule :C16H22Cl3N5Couleur et forme :SolidMasse moléculaire :390.74C5aR2 agonist P32 acetate
C5aR2 agonist P32 acetate (Ac-RHYPYWR-OH), a selective agonist for C5aR2, has been shown to induce various immunomodulatory activities both in vitro and in vivo. It modulates cell signaling via the downregulation of C5aR1-mediated pathways and can also function independently of C5aR1.Formule :C54H70N16O11·xC2H4O2Couleur et forme :SolidMasse moléculaire :1119.23 (free base)Leukadherin-1
CAS :Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Formule :C22H15NO4S2Degré de pureté :98% - 98.49%Couleur et forme :SolidMasse moléculaire :421.49Iptacopan hydrochloride
CAS :Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.Formule :C25H31ClN2O4Degré de pureté :98.32% - 99.87%Couleur et forme :SolidMasse moléculaire :458.98Ref: TM-T9189
1mg59,00€5mg127,00€10mg205,00€25mg371,00€50mg620,00€100mg1.026,00€200mg1.388,00€1mL*10mM (DMSO)128,00€C3a (70-77)
CAS :C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a.Formule :C35H61N13O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :823.94Danicopan
CAS :Danicopan (ACH-4471), an oral factor D inhibitor, binds strongly (Kd 0.54 nM) and may treat PNH and aHUS.Formule :C26H23BrFN7O3Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :580.41Ref: TM-T8509
1mg96,00€2mg136,00€5mg215,00€10mg328,00€25mg557,00€50mg797,00€100mg1.103,00€1mL*10mM (DMSO)274,00€MASP2 Protein, Human, Recombinant (His)
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood.Couleur et forme :Lyophilized PowderMasse moléculaire :46.9 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18 kDa&25-30 kDa based on Tris-Bis PAGE result.C1QL1 Protein, Mouse, Recombinant (His)
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.Couleur et forme :Lyophilized PowderMasse moléculaire :26.9 kDa (predicted)(Rel)-Factor B-IN-5
CAS :(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.Formule :C27H32N2O4Degré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :448.55Complement C3 Protein, Mouse, Recombinant (His)
Complement C3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :36.34 kDa (predicted); 32.39 kDa (reducing conditions)Greziprubart
Greziprubart is a humanized IgG1κ monoclonal antibody that targets C5a, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Couleur et forme :Odour LiquidCR1 Protein, Human, Recombinant
CR1 Protein, Human, Recombinant is expressed in E. coli with Tag Free. The accession number is P17927.Couleur et forme :Lyophilized PowderMasse moléculaire :21.6 kDa (Predicted)Complement factor B Protein, Mouse, Recombinant (His)
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb.Couleur et forme :Lyophilized PowderMasse moléculaire :87.0 kDa (predicted)Cyclosporin A
CAS :Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor.Formule :C62H111N11O12Degré de pureté :99.00% - 99.85%Couleur et forme :White PowderMasse moléculaire :1202.61C1q Protein (human)
C1qProtein (human) serves as a subunit in the complement system. It binds to a variety of ligands from self, non-self, and altered-self, contributing to the balance of the immune system, promoting tissue repair, and defending against pathogens.Formule :C19H24N4O3SCouleur et forme :SolidMasse moléculaire :388.48Complement Factor D/CFD Protein, Human, Recombinant (hFc)
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.Couleur et forme :Lyophilized PowderMasse moléculaire :51.2 kDa (predicted). Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.C1QB Protein, Human, Recombinant (His)
Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system.Couleur et forme :Lyophilized PowderMasse moléculaire :25.2 kDa (predicted); 30 kDa (reducing condition, due to glycosylation)Complement C5 Protein, Cynomolgus, Recombinant (His)
Complement C5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :188.1 kDa (predicted); 106.3 and 75.8 kDa (reducing conditions)Complement factor D Protein, Rat, Recombinant (His)
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternateCouleur et forme :Lyophilized PowderMasse moléculaire :27.8 kDa (predicted)Complement C4-B Protein, Mouse, Recombinant (His)
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway.Couleur et forme :Lyophilized PowderMasse moléculaire :39.0 kDa (predicted)Complement C7 Protein, Human, Recombinant (His)
Complement C7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :92.6 kDa (predicted); 92-98 kDa (reducing conditions)C1q Protein (Mouse)
C1qProtein (Mouse) is a subunit of the complement system. It recognizes a variety of ligands and plays roles in maintaining immune system balance, promoting tissue repair, and defending against pathogens.Couleur et forme :Odour SolidCFI Protein, Mouse, Recombinant (His)
CFI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :66.75 kDa (predicted); 126.1 kDa, 59.3 kDa and 46.7 kDa (reducing conditions)C1SB Protein, Mouse, Recombinant (His & Myc)
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system.Couleur et forme :Lyophilized PowderMasse moléculaire :82.4 kDa (predicted)NDT 9513727
CAS :NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.Formule :C36H35N3O4Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :573.68C1QBP Protein, Human, Recombinant (His)
C1QBP Protein, Human, Recombinant (His) is expressed in E.Couleur et forme :Lyophilized PowderMasse moléculaire :24.8 kDa (predicted); 36 kDa (reducing conditions)Complement C5 Protein, Rat, Recombinant (His & Myc)
Complement C5 Protein, Rat, Recombinant (His & Myc) is expressed in E.Couleur et forme :Lyophilized PowderMasse moléculaire :14.0 kDa (predicted)C5AR1 Protein, Human, Recombinant (Cell-Free, His)
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.Degré de pureté :90%Couleur et forme :Lyophilized PowderMasse moléculaire :40.7 kDa (predicted)EG01377 2HCl
CAS :EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377Formule :C26H32Cl2N6O6S2Degré de pureté :99.56%Couleur et forme :SoildMasse moléculaire :659.6Ref: TM-T11154L
1mg145,00€5mg354,00€10mg540,00€25mg869,00€50mg1.188,00€100mg1.596,00€500mg3.202,00€1mL*10mM (DMSO)512,00€CP-289
CAS :CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.Formule :C30H35ClN2O2Degré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :491.06Ref: TM-T60161
1mg115,00€2mg172,00€5mg255,00€10mg374,00€25mg562,00€50mg787,00€100mg1.074,00€500mg2.147,00€1mL*10mM (DMSO)305,00€Complement C5a Protein, Mouse, Recombinant, Biotinylated
Complement C5a Protein, Mouse, Recombinant, Biotinylated is expressed in E.Couleur et forme :Lyophilized PowderMasse moléculaire :9 kDa (predicted)C5AR1 Protein-VLP, Human, Recombinant (His)
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.Couleur et forme :Lyophilized PowderMasse moléculaire :41.1 kDa (predicted)Complement C8b Protein, Human, Recombinant (His)
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane ofCouleur et forme :Lyophilized PowderMasse moléculaire :67.0 kDa (predicted)SB290157 trifluoroacetate
CAS :SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).Formule :C24H29F3N4O6Degré de pureté :98.93% - 99.89%Couleur et forme :SolidMasse moléculaire :526.51Complement C3 Protein, Cynomolgus, Recombinant (His)
Complement C3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :90.3%Couleur et forme :Lyophilized PowderMasse moléculaire :186.40 kDa (predicted)C1s-A subcomponent Protein, Mouse, Recombinant (His)
C1s-A subcomponent Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :76.6 kDa (predicted)C3a Receptor Agonist
CAS :C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.Formule :C27H35N3O2Degré de pureté :97.5%Couleur et forme :SolidMasse moléculaire :433.59C1QA Protein, Human, Recombinant (His & Myc)
C1QA Protein, Human, Recombinant (His & Myc) is expressed in E. coli.Couleur et forme :Lyophilized PowderMasse moléculaire :30.7 kDa (predicted)C1s Protein, Human, Recombinant (His)
Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses.Couleur et forme :Lyophilized PowderMasse moléculaire :76.3 kDa (predicted); 82.06 kDa, 56.59 kDa and 33.36 kDa (reducing condition, due to glycosylation)TLQP-21 TFA
TLQP-21 TFA (TLQP-21 Trifluoroacetate) 是一种 VGF 衍生肽,可通过结合后折叠机制激活C3aR1 受体。Degré de pureté :98%C1QA Protein, Mouse, Recombinant (His)
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.Degré de pureté :90% - 92%Couleur et forme :Lyophilized PowderMasse moléculaire :25.6 kDa (predicted)Complement C5 Protein, Human, Recombinant (His & FLAG)
Complement C5 Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag.Degré de pureté :96.1%Couleur et forme :Lyophilized PowderMasse moléculaire :188.8 kDa (predicted)(Z)-Leukadherin-1
CAS :(Z)-Leukadherin-1 (ADH-503 free base) is an allosteric agonist of CD11b.Formule :C22H15NO4S2Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :421.49Complement C8a Protein, Human, Recombinant (His)
Complement C8a Protein, Human, Recombinant (His) is expressed in E. coli.Couleur et forme :Lyophilized PowderMasse moléculaire :65.8 kDa (predicted)C1QL3 Protein, Mouse, Recombinant (His & Myc)
May regulate the number of excitatory synapses that are formed on hippocampus neurons.Couleur et forme :Lyophilized PowderMasse moléculaire :28.6 kDa (predicted)Complement C2 Protein, Human, Recombinant (His)
Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :98.6%Couleur et forme :Lyophilized PowderMasse moléculaire :82.5 kDa (predicted)Eculizumab
CAS :Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5Degré de pureté :98.20%Couleur et forme :LiquidMasse moléculaire :148 kDaComplement C5 Protein, Cynomolgus, Recombinant
Complement C5 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells.Couleur et forme :Lyophilized PowderMasse moléculaire :8.41 kDa (predicted); 12.42 kDa (reducing conditions)
