Glucides et Glycoconjugués

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Applications Labelled Azacytidine (A796000), a potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase. References Kusaba, H., et al.: Eur. J. Biochem., 262, 924 (1999), Broday, L., et al.: Mol. Cell Biol., 19, 3198 (1999), Qian, X., et al.: Am. J. Pathol., 153, 1475 (1999), Canova, C., et al.: Mech. Ageing Dev., 101, 153 (1998)

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

1-D-a-Galactopyranosyl-4-O-[1-(2-octadecylthioethyl)-(b-D-galactopyranoside)] is a complex carbohydrate that contains a fluorinated sugar. It is synthesized from a monosaccharide and an oligosaccharide and glycosylated with a polysaccharide. The compound has been modified to include methylation and click modification. 1-D-a-Galactopyranosyl-4-O-[1-(2-octadecylthioethyl)-(b-D-galactopyranoside)] can be purchased in high purity from the CAS registry number of 538570-75-6.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Found in milk with immunoprotective effects against pathogens in newborns and aids development and maturation of the immune system and gut microbiota. Suppresses adhesion and infectivity of bacteria and viruses, such as influenza viruses, HIV-1 and rotaviruses. Inhibits binding of cholera toxin.

Applications Isotope labelled Fructose1,6-bisphosphate is an intermediate that lies within the glycolysis metabolic pathway and is also an allosteric activator of pyruvate kinase. References Hinder, L.M., et al.: J. Endocriol., 216, 1 (2013); Takubo, K., et al.: Cell. Stem. Cell., 12, 49 (2013); Kalam, Y., et al.: Clin. Toxciol., 50, 546 (2012);

Applications A fluorinated derivative of Erythromycin (E649950). A macrolide antibiotic. References Labro, M. et al.: Macrolide Antibiot., 37 (2002); Lo Bue, A.M. et al.: J. Chemother., 13, 255 (2001); Fera, M.T. et al.: Int. J. Antimicrob. Agents, 17, 151 (2001);

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

The blood group H disaccharide is a custom synthesis, complex carbohydrate with an Oligosaccharide and CAS No. It is a Polysaccharide that can be modified by methylation or glycosylation. The blood group H disaccharide has a saccharide with a high purity and high purity. It is fluorinated at the 2' position of the sugar moiety in the backbone. The blood group H disaccharide can be synthesized using Click chemistry which involves coupling of two molecules in a single step. This process uses an azide-alkyne cycloaddition to covalently link two molecules together.

NA2 is a glycan that is a specific antigen binding molecule. It binds to the CD20 receptor on the surface of human B lymphocytes, which are involved in the development of cancer and inflammatory diseases. NA2 can be used for the treatment of these diseases, as well as cancers that express CD20 receptors. NA2 is generated from endogenous molecules that have been modified by introducing galactose into the carbohydrate backbone. These molecules also form a linker with bendamustine, which is an anticancer drug.

Chondroitin sulphate tetrasaccharide ammonium salt is a synthetic glycosaminoglycan that is used to study the structure, function and interactions of glycosaminoglycans. The polysaccharide is composed of four sugars: glucuronic acid, galactose, N-acetylgalactosamine and glucosamine. The chemical structure of this compound is characterized by its high purity, low viscosity and excellent solubility in water. It can be custom synthesized with any desired degree of substitution (0% to 100%). This product can be used as an additive in cosmetics or as a reagent in biochemistry experiments.

Applications: Laninamivir (L174000) prodrug; a novel long-acting neuraminidase inhibitor. References Neumann, G., et al.: Nature, 459, 931 (2009), Yamashita, M., et al.: Antimicrob. Agents Chemother., 53, 186 (2009),

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

N-acetyllactosamine is a monosaccharide that belongs to the group of n-acetyllactosamine. It can be found in the form of an agglutinin, lactose, and lectin. The conformation of this molecule is an equilibrium between its alpha and beta forms. The pyridine can act as an acid catalyst for the alpha conformation. There are two forms of this molecule: one synthesized from D-glucose and one synthesized from D-galactose. 1,6-Anhydro-4-O-b-D-galactopyranosyl-b-D-glucopyranose is synthesized from D-glucose. Oligosaccharides containing this molecule have been expressed in Saccharomyces cerevisiae cells and purified by affinity chromatography on columns that contain immobilized antibody to human serum albumin. This molecule has been shown

4,6-O-Benzylidene-D-maltose is an oligosaccharide that is a high purity custom synthesis. It has a Click modification and can be synthesized using the Fluorination and Glycosylation reaction. 4,6-O-Benzylidene-D-maltose is soluble in water and ethanol, but insoluble in ether. This product is listed as CAS No. 93417-41-5 and has a Methylation modification. 4,6-O-Benzylidene-D-maltose is also found in saccharides, carbohydrates, and complex carbohydrates.

D-Mannopyranose (Mannose) is a hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants.

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

The conformation of the 2-[[2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-βDglucopyranosyl)-βDglucopyranosyl]oxy]ethyl]carbamic acid phenylmethyl ester molecule has been studied by X-ray crystallography. The molecule adopts a chair conformation with the two acetyl groups occupying equatorial positions. The molecule is planar with an angle of 110° between the NH and CO axes. The calculated electron diffraction pattern was in good agreement with the experimental data. The analysis yielded a set of independent amplitudes for each reflection that were analysed to give structure constants and electron distributions.

NA2FB N-Glycan is a custom synthesis that is prepared on a glycosylation scale. The monosaccharide units are linked by alpha-1,6 or alpha-1,3 glycosidic bonds to form a linear chain. The saccharides are attached to each other via the formation of beta-1,4 glycosidic bonds. NA2FB N-Glycan has a high purity and modification. It is available in various forms such as oligosaccharide, polysaccharide, saccharide and carbohydrate. This product can be used for research purposes or as raw material in the production of medicine.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

3-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-galactose is a synthetic glycosylation of galactose and acetamide. This product is a high purity, custom synthesis with methylation, monosaccharide, and polysaccharide modifications. 3-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-galactose is available in bulk quantities.

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarotetraose is reported to have potential for novel cosmeceuticals.

Lewis Y-O-(CH2)8-biotin is a carbohydrate with the chemical formula (CHO)(CO)3OH. It is a methylated and glycosylated oligosaccharide that has been custom synthesized for use in biotechnology applications. Lewis Y-O-(CH2)8-biotin has been fluorinated at the C5 position to improve its stability and prevent hydrolysis, which may be due to its high purity. This carbohydrate is not commercially available and must be custom synthesized.

Applications Uridine-2-13C-1,3-15N2 is labelled Uridine (U829910) which is a nucleoside widely distributed in nature. Uridine is one of the four basic components of ribonucleic acid (RNA) References Lorine, P., et al.: J. Biol. Chem., 178, 439 (1949); Grakoui, A., et al.: J. Virol., 63, 5216 (1989); Strauss, J., et al.: Microbiol. Rev., 58, 491 (1994); Lin, Y., et al.: Virology, 292, 78 (2002);

Sucrose (D-(+)-Saccharose) is a nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.

Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS, IF<br> Application: Human

Neu5Ac(a2-6)Gal(b1-4)GalNAc is a synthetic, fluorinated monosaccharide. It is an oligosaccharide that has been custom synthesized and glycosylated. It is a complex carbohydrate that has been modified with methylation and click chemistry. Neu5Ac(a2-6)Gal(b1-4)GalNAc has CAS number 383365-43-3. This product is available in high purity and can be used in the synthesis of polysaccharides.

2-Acetamido-4-O-[2-acetamido-4-O-(b-D-glucopyranosyl)-3,6-di-O-(a-D-mannopyranosyl)-2,6-di-O-(a,b,c,d)-D mannopyranosyl]-2,6-di-O-(a,b,c,d)-D mannopyranosyl]-2 deoxy -b D thioglucopyranose is a carbohydrate that belongs to the class of saccharides. This compound is modified with fluorination and methylation and can be custom synthesized. It has high purity and can be glycosylated or click modified.

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Antibody Type: Rabbit Monoclonal<br> Application: FACS<br> Application: Human

Applications Contained in tobacco flavor additives. References Sumoto, K., et al.: Chem. Pharm. Bull., 39, 792 (1991), Shimamura, T., et al.: Biosci., Biotechnol., Biochem., 67, 295 (2003),

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Please enquire for more information about N-Glycolylneuraminic acid dimer sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Stability Store in freezer Applications Prepared by acetolysis of chitin. Studies have shown this compound to have anti tumor effects. References Barker, S.A., et al.: J. Chem. Soc., 2218 (1958); Suzuki, K., et al.: Carbohydrate Research, 151, 403 (1986)

Remogliflozin is an effective sodium-glucose transporter 2 inhibitor (Kis = 12.4 and 26 nM for human and rat SGLT2, respectively).

1,6-Anhydro-b-D-cellopentose is a synthetic cello-oligomer

Monosialyllacto-N-hexaose II is a synthetic, fluorinated oligosaccharide that is synthesized by glycosylation of the sugar monosialyllactose. Monosialyllacto-N-hexaose II has a molecular weight of 514.5 Da and is soluble in water. It can be used for applications such as custom synthesis, modification of complex carbohydrates, or click chemistry.

m-3M3FBS is a phospholipase C (PLC) activator.

Biotin impurity C is a metabolite that is found in drugs that contain biotin. It is an impurity standard for HPLC analysis, which can be used to identify and quantify the amount of biotin in a drug product. Biotin impurity C is also used as an analytical standard. This compound has been shown to have pharmacological properties, such as anti-inflammatory effects and immunomodulatory effects.

2-Acetamido-4-O-(2-acetamido-3,6-di-O-acetyl-2,4-dideoxy-b-D-glucopyranosyl)-1,3,6-tri-O-benzyl-2-deoxy -bDglucopyranoside is a methylated oligosaccharide. It can be synthesized by the click reaction of 2,4,6--trichlorobenzaldehyde with 3,6--diacetyl--2,4--dideoxy--bDglucopyranose. This compound has an acetamido group on C3 and a benzoyl group on C6. The molecular weight of this compound is 1076 g/mol.

Man-6 Glycan, 2-AB labelled is a custom synthesis of mannose-6-phosphate, a monosaccharide. The molecule contains six carbons and one phosphate group. It can be modified with fluorination, methylation, or click modification. This glycan is synthesized by the addition of an oligosaccharide to a polysaccharide. Mannose-6-phosphate is an Oligosaccharide that carries out glycosylation reactions in the body. It is used as a precursor for other glycans such as N-Acetylglucosamine and N-Acetylgalactosamine.

Stability Hygroscopic Applications A macrolide compound which is known to have antibacterial activity, and is useful in the therapy of bacterial infections in mammals. Antibiotic. References Broto, P., et al.: Eur. J. Med. Chem., 19, 71 (1984), Farrar, V., et al.: J. Med. Chem., 36, 3517 (1993), Clark, D., et al.: J. Pharm. Sci., 88, 807 (1999),

Antibody Type: Rabbit Monoclonal<br> Application: ELISA, FACS<br> Application: Human

Applications A new acyl derivative of Tylosin (T947650) produced by microbial transformation. References Okamoto, R., et al.: J. Antibiotics, 33, 1300 (1980),

Stability Hygroscopic Applications Saikosaponin A was shown to exhibit anti-inflammatory activities by suppressing activation of NF-kB signaling pathway. References Wu, S.J., et al.: Am. J. Chin. Med., 38, 99 (2010); Wu. S.J., et al.: J. Med. Food., 11, 224 (2008); Yoon, S.S., et al.: Neurosci. Lett., 529, 97 (2012); Lu, C.N., et al.: Int. Immunopharmacol., 14, 121 (2012);

Biotin-PEG3-azide is a PEG-based PROTAC linker can be used in PROTAC synthesis.

3,4,6-Tri-O-acetyl-2-O-(2,3,4-tri-O-benzoyl-a-L-fucopyranosyl)-D-galactopyranosyl trichloroacetimidate is a sugar. It is a complex carbohydrate that is a polysaccharide made up of three monosaccharides: D-, L-, and erythro-. This molecule has been fluorinated at the C3 position. The CAS number for this compound is 123787−06−1. 3,4,6-Tri-O-acetyl-2-O-(2,3,4-tri-O--benzoyl--a--L--fucopyranosyl)-D--galactopyranosyl trichloroacetimidate is custom synthesized and has high purity.

Sialyl Lewis X ceramide is a monosaccharide that belongs to the pentasaccharide group. It is expressed in the cells of leukemia and erythrocytes, as well as other tissues. Sialyl Lewis X ceramide is a hybrid molecule that has a backbone consisting of four sugar molecules and an amino acid sequence, with hydroxyl groups on one end and an acetyl glucosamine on the other end. The molecule has a carbohydrate skeleton consisting of galactose, glucose, mannose, and sialic acid. Sialyl Lewis X ceramide also interacts with selectins to mediate leukocyte-endothelial interactions in inflammation.

Monofucosyl (1-2)-iso-lacto-N-octaose II is an oligosaccharide that is found in human milk

2-O-(a-D-Galactopyranosyl)-b-D-fucopyranosyl propylamine is a glycosylated synthetic compound with a molecular weight of 726.2. It is an excellent substrate for the glycosylation of proteins and nucleic acids, as well as an excellent candidate for Click modification, fluorination, saccharide modification and custom synthesis. 2-O-(a-D-Galactopyranosyl)-b-D-fucopyranosyl propylamine is a high purity product available in bulk quantities.