Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
Produits appartenant à la catégorie "Nucléosides et Nucléotides"
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Capecitabine
CAS :Formule :C15H22FN3O6Couleur et forme :White To Off-White SolidMasse moléculaire :359.35Azacitidine Impurity 16
Formule :C10H14N4O6Couleur et forme :White To Off-White SolidMasse moléculaire :286.24NADPH tetrasodium salt
CAS :NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety ofFormule :C21H26N7Na4O17P3Degré de pureté :100% - 99.65%Couleur et forme :SolidMasse moléculaire :833.35Azacitidine Impurity 13
CAS :Formule :C8H13N5O5Couleur et forme :White To Off-White SolidMasse moléculaire :259.22ent-Entecavir
CAS :Produit contrôléApplications ent-Entecavir is an enantiomeric impurity of the antiviral drug Entecavir (E558900). References Ruediger, E. et al.: Tetrahed. Lett., 45, 739 (2004): Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997);Formule :C12H15N5O3Couleur et forme :NeatMasse moléculaire :277.28Casein kinase 1δ-IN-9
CAS :Casein kinase 1δ-IN-9 is a Quinone reductase 2 inhibitor with IC50 of 0.6μM.Formule :C15H12ClN3Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :269.73Ref: TM-T64376
1mg96,00€5mg197,00€10mg295,00€25mg474,00€50mg638,00€100mg848,00€200mg1.121,00€1mL*10mM (DMSO)180,00€Entecavir (1S,3S,4S) diastereomer
CAS :Entecavir is a drug product that is custom synthesized to order. It has a purity of >98% and is made up of the 1S,3S,4S diastereomer. Entecavir is an antiviral drug that belongs to the nucleoside analog family and inhibits viral replication by inhibiting DNA polymerase α. The metabolism studies for entecavir have been completed and it was found that entecavir undergoes hydrolysis by esterases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Entecavir also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.Formule :C12H15N5O3Degré de pureté :Min. 95%Masse moléculaire :277.28 g/molAdefovir-d4
CAS :Formule :C8H8D4N5O4PCouleur et forme :White To Off-White SolidMasse moléculaire :277.21EIDD-2801
CAS :EIDD-2801 (Molnupiravir) is a prodrug for N 4-hydroxycytidine, effective against influenza and various coronaviruses.Formule :C13H19N3O7Degré de pureté :100% - 99.70%Couleur et forme :SolidMasse moléculaire :329.31Ref: TM-T8309
1g657,00€5mg40,00€10mg60,00€25mg79,00€50mg119,00€100mg187,00€200mg350,00€500mg449,00€1mL*10mM (DMSO)66,00€Emtricitabine triphosphate tetrasodium salt
CAS :Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleosideFormule :C8H9FN3Na4O12P3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.11rac-Melphalan EP Impurity B DiHCl
CAS :Formule :C13H18N2O3·2HClCouleur et forme :Pale Purple SolidMasse moléculaire :250.30 2*36.462'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine
2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is an analytical standard that is used in research and development of drugs. This compound has been designated as an impurity in a drug product. It has also been used as a reference standard for HPLC analysis. 2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is a metabolite of the drug product. This compound is not found in nature and has been synthesized artificially.Formule :C9H12F2N2O6Degré de pureté :Min. 95%Masse moléculaire :282.2 g/molGS-443902
CAS :Remdesivir triphosphate (GS-443902) inhibits RSV/HCV RdRp with IC50s: 1.1/5 µM.Formule :C12H16N5O13P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :531.2Peramivir Impurity 29
CAS :Formule :C15H28N4O4Couleur et forme :White To Off-White SolidMasse moléculaire :328.41Ribavirin Impurity 38
Formule :C5H7N3O3Couleur et forme :White To Off-White SolidMasse moléculaire :157.13Ganciclovir Impurity 1 HCl (Mixture of Diastereomers)
CAS :Formule :C15H24N6O5·HClCouleur et forme :White To Off-White SolidMasse moléculaire :368.39 36.46Capecitabine Impurity 9
CAS :Formule :C20H30FN3O9Couleur et forme :White To Off-White SolidMasse moléculaire :475.47Adenosine 5'-Triphosphate as disodium salt
CAS :Formule :C10H14N5O13P3NaMasse moléculaire :505.17 2 22.99Decitabine impurity 5
Formule :C13H16O5Couleur et forme :White To Off-White SolidMasse moléculaire :252.27Ademethionine-d3 1,4-Butanedisulfonate
CAS :Formule :C19H30D3N6O11S3C4H8O6S2Masse moléculaire :620.70 122.16rac-Melphalan-d8
CAS :Formule :C13H10D8Cl2N2O2Couleur et forme :White To Off-White SolidMasse moléculaire :313.25Cytarabine EP Impurity I
CAS :Formule :C10H15N3O5Couleur et forme :White To Off-White SolidMasse moléculaire :257.25Emtricitabine Sulfoxide
CAS :Produit contrôléFormule :C8H10FN3O4SCouleur et forme :NeatMasse moléculaire :263.25Peramivir Impurity 17
CAS :Formule :C12H19NO4Couleur et forme :White To Off-White SolidMasse moléculaire :241.295-Azacytidine
CAS :5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formule :C8H12N4O5Degré de pureté :99.31% - 99.79%Couleur et forme :Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Masse moléculaire :244.2Etravirine-d6
CAS :Formule :C20H9D6BrN6OCouleur et forme :White To Off-White SolidMasse moléculaire :441.322,3'-Anhydrothymidine
CAS :2,3'-Anhydrothymidine is a piperidine-containing nucleoside analog that inhibits the replication of HIV and other viruses. It is structurally related to acyclovir, but has an increased resistance to viral inactivation by acyclovir-resistant strains. 2,3'-Anhydrothymidine binds to the ribose sugar of the viral nucleic acid and prevents the formation of a covalent bond between the 5' hydroxyl group of ribose and the 3' phosphate group. It also inhibits protein synthesis by interfering with the incorporation of amino acids into proteins. 2,3'-Anhydrothymidine has been shown to be effective against human immunodeficiency virus type 1 (HIV-1) in animal models and clinical studies.Formule :C10H12N2O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :224.21 g/molPyrithioxin
CAS :Pyrithioxin (Encefabol), a nootropic, enhances cerebral metabolism and, with HV, aids hemiplegic stroke recovery.Formule :C16H20N2O4S2Degré de pureté :98.40%Couleur et forme :Almost White Crystalline PowderMasse moléculaire :368.47Aciclovir (Acyclovir) EP Impurity M
CAS :Formule :C12H15N5O5Couleur et forme :Off-White SolidMasse moléculaire :309.28Valaciclovir EP Impurity G (Valacyclovir USP Related Compound G, DMAP)
CAS :Formule :C7H10N2Couleur et forme :White To Off-White SolidMasse moléculaire :122.172-[[2-(Acetylamino)-6-oxo-1,6-dihydro-9H-purin-9-yl]methoxy]-3-hydroxypropyl Acetate
CAS :Couleur et forme :NeatLY-404187
CAS :LY404187 is a positive allosteric modulator of AMPA receptorsFormule :C19H22N2O2SDegré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :342.46Ref: TM-T7706
2mg35,00€5mg52,00€10mg90,00€25mg164,00€50mg239,00€100mg339,00€200mg472,00€1mL*10mM (DMSO)58,00€Lamivudine EP Impurity H
CAS :Formule :C8H11N3O4SCouleur et forme :White To Off-White SolidMasse moléculaire :245.25(S)-4-Hydroxypyrrolidin-2-one
CAS :Produit contrôléFormule :C4H7NO2Couleur et forme :NeatMasse moléculaire :101.10Clofarabine
CAS :Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormule :C10H11ClFN5O3Couleur et forme :White Off-White PowderMasse moléculaire :303.05345Fludarabine Phosphate EP Impurity F
CAS :Formule :C12H18FN5O8PCouleur et forme :White To Off-White SolidMasse moléculaire :391.28Gemcitabine Diphosphate-13C-15N2 Tri(triethylamine) Salt
Formule :C15N2C8H13F2NO10P2·3C6H15NMasse moléculaire :426.14 3 101.19Decitabine Impurity 4 (Methyl-2-deoxy-alfa-D-Ribopyranoside)
CAS :Formule :C6H12O4Couleur et forme :White To Off-White SolidMasse moléculaire :148.16Capecitabine Impurity 14 (Mixture of Diastereomers)
Formule :C22H28FN3O11Couleur et forme :Off-White SolidMasse moléculaire :529.472-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]propane-1,3-diyl Dipropanoate (Ganciclovir Dipropionate)
CAS :Produit contrôléFormule :C15H21N5O6Couleur et forme :NeatMasse moléculaire :367.36Dapagliflozin alfa-Isomer
CAS :Formule :C21H25ClO6Couleur et forme :White To Off-White SolidMasse moléculaire :408.88Peramivir Enantiomer
CAS :Formule :C15H28N4O4Couleur et forme :White To Off-White SolidMasse moléculaire :328.41Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside
CAS :Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside is a synthetic impurity standard for the drug product. It has been used in studies on metabolism and as an analytical reference material. Methyl 2-deoxy-3,4-di-O-toluoyl-D-ribopyranoside is also available as a custom synthesis at high purity.Formule :C22H24O6Degré de pureté :Min. 95%Couleur et forme :White powder.Masse moléculaire :384.42 g/molCreatine Phosphate Impurity 7 Disodium Salt
CAS :Formule :C5H7NO4·2NaMasse moléculaire :145.12 2 22.99Ganciclovir sodium
CAS :Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.Formule :C9H13N5NaO4Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :278.222-Amino-2'-deoxyadenosine (2,6-diamino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-Purine)
CAS :Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormule :C10H14N6O3Couleur et forme :White PowderMasse moléculaire :266.11274Fluorouracil EP Impurity D
CAS :Formule :C5H6N2O3Couleur et forme :White To Off-White SolidMasse moléculaire :142.11Molnupiravir
CAS :Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability.Cost-effective and quality-assured.Formule :C13H19N3O7Degré de pureté :100% - 99.98%Couleur et forme :SolidMasse moléculaire :329.31Ref: TM-T60951
1g1.026,00€5mg40,00€10mg60,00€25mg79,00€50mg119,00€100mg187,00€200mg354,00€500mg748,00€1mL*10mM (DMSO)66,00€Entecavir monohydrate
CAS :Entecavir monohydrate (BMS-200475) is a selective inhibitor of the replication of the hepatitis B virus (HBV). It, a new deoxyguanine nucleoside analog.Formule :C12H15N5O3·H2ODegré de pureté :100% - 99.8%Couleur et forme :White Crystalline PowderMasse moléculaire :295.3S-(5'-Adenosyl)-L-homocysteine
CAS :Formule :C14H20N6O5SCouleur et forme :White To BrownMasse moléculaire :384.41Dapagliflozin Impurity 2
CAS :Formule :C15H14BrClOCouleur et forme :White To Off-White SolidMasse moléculaire :325.63Remdesivir impurity 12
CAS :Remdesivir impurity 12 is a drug product that is used in research and development. It is a synthetic impurity standard for HPLC analytical methods. Remdesivir impurity 12 is an impurity of the drug, remdesivir, which has antiviral activity against HIV-1. Metabolism studies have been conducted to investigate how this impurity affects the pharmacokinetics of remdesivir. The use of synthetic material ensures high purity and quality for this product.Formule :C21H31N6O8PDegré de pureté :Min. 95%Masse moléculaire :526.48 g/molAdenosine
CAS :Applications Adenosine is a nucleotide. References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010);Formule :C10H13N5O4Couleur et forme :NeatMasse moléculaire :267.24L-Uridine 5'-Monophosphate Diammonium Salt
CAS :Formule :C9H11N2O9P·2NH4Masse moléculaire :322.17 2*18.04N2-Nitroso Folinic Acid (N2-Nitroso Folic Acid USP Related Compound A (Free Form), N2-Nitroso Leucovorin)
Formule :C20H22N8O8Masse moléculaire :502.44Fludarabine Phosphate EP Impurity D
CAS :Formule :C5H4FN5Couleur et forme :Off-White SolidMasse moléculaire :153.12Remdesivir Impurity 8
Formule :C30H39N6O8PCouleur et forme :White To Off-White SolidMasse moléculaire :642.65Ribavirin EP Impurity A (Ribavirin USP Related Compound A)
CAS :Formule :C8H11N3O6Couleur et forme :White To Off-White SolidMasse moléculaire :245.19Hydroxocobalamin Acetate (Vitamin B12 Analog)
CAS :Formule :C64H92CoN13O16PCouleur et forme :Dark Red SolidMasse moléculaire :1389.42Cytidine 2':3'-cyclic monophosphate monosodium salt
CAS :Formule :C9H11N3O7P·NaMasse moléculaire :304.18 22.99Azathioprine EP Impurity F (Didanosine EP Impurity A, Didanosine USP Related Compound A, Hypoxanthine)
CAS :Formule :C5H4N4OMasse moléculaire :136.11Folic Acid EP Impurity G Ditrifluoroacetate
CAS :Formule :C19H19N7O6·2C2HF3O2Masse moléculaire :441.40 2*114.02Melphalan EP Impurity B DiHCl
CAS :Formule :C13H18N2O3·2HClCouleur et forme :Off-White SolidMasse moléculaire :250.13 2*36.46Gemcitabine EP Impurity B-13C-15N2 HCl (α-Gemcitabine-13C-15N2 HCl)
CAS :Formule :C813CH11F2N15N2O4·HClCouleur et forme :White To Off-White SolidMasse moléculaire :266.18 36.46GKT136901
CAS :GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of PeroxynitriteFormule :C19H15ClN4O2Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :366.82'-Deoxyadenosine ((2R,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol)
CAS :Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormule :C10H13N5O3Couleur et forme :White PowderMasse moléculaire :251.10184Folinic Acid Impurity 5 (4-Aminobenzoyl D-Glutamic Acid)
CAS :Formule :C12H14N2O5Masse moléculaire :266.26Dapagliflozin-d5
CAS :Formule :C21H20D5ClO6Couleur et forme :White To Off-White SolidMasse moléculaire :413.911-(2,3-Di-O-acetyl-5-deoxy-β-D-ribofuranosyl)-4-amino-5-fluoropyrimidin-2(1H)-one
CAS :Produit contrôléFormule :C13H16FN3O6Couleur et forme :NeatMasse moléculaire :329.28Zanamivir
CAS :Zanamivir (GG167) is a guanido-neuraminic acid that is used to inhibit NEURAMINIDASE.Formule :C12H20N4O7Degré de pureté :98.84% - 99.98%Couleur et forme :Colorless Crystalline SolidMasse moléculaire :332.31Zidovudine diphosphate
CAS :Zidovudine diphosphate, an NRTI antiretroviral, treats HIV/AIDS by blocking reverse transcriptase, preventing viral DNA synthesis.Formule :C10H15N5O10P2Couleur et forme :SolidMasse moléculaire :427.2Peramivir Impurity 18
CAS :Formule :C12H19NO4Couleur et forme :White To Off-White SolidMasse moléculaire :241.29Cangrelor Impurity 6
CAS :Formule :C10H13N5O4SCouleur et forme :Off-White SolidMasse moléculaire :299.31Ganciclovir EP Impurity H
CAS :Formule :C9H13N5O4Couleur et forme :White To Off-White SolidMasse moléculaire :255.23L-Tetrahydrofolic Acid (>70% when packaged)
CAS :Produit contrôléStability We have observed that this material decomposes steadily over time. Use immediate Applications L-Tetrahydrofolic Acid is a folic acid derivative and coenzyme involved in the metabolism of amino and nucleic acids. We have observed that this material decomposes steadily over time. Use immediately upon receipt. References Prinz-Langenohl, R., et al.: Brit. J. Pharmacol., 158, 2014 (2009), Martin, H., et al.: Anal. Biochem., 402, 137 (2010), Dasarathy, J., et al.: Am. J. Clin. Nut., 91, 357 (2010), Karas-Kuzelicki, N., et al.: Clin. Biochem., 43, 37 (2010),Formule :C19H23N7O6Couleur et forme :NeatMasse moléculaire :445.43Sofosbuvir Impurity 68
CAS :Formule :C31H26FN3O7Couleur et forme :White To Off-White SolidMasse moléculaire :571.56Famciclovir Impurity 7
CAS :Formule :C10H15N5O3Couleur et forme :White To Off-White SolidMasse moléculaire :253.26Brivudine Impurity 6 (Mixture of Isomers)
CAS :Formule :C4H6Br2Couleur et forme :Pale Yellow Clear LiquidMasse moléculaire :213.90Folic Acid-13C5
CAS :Applications A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate. References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),Formule :C5C14H19N7O6Couleur et forme :Dark Yellow To Dark BrownMasse moléculaire :446.36Valaciclovir EP Impurity E (Valacyclovir USP Related Compound E)
CAS :Formule :C21H26N6O6Masse moléculaire :458.48Sofosbuvir Nucleoside Derivative (GS-331007)
CAS :Formule :C10H13FN2O5Couleur et forme :Off-White To Yellow SolidMasse moléculaire :260.22Dapagliflozin USP Related Compound A
CAS :Formule :C21H25BrO6Couleur et forme :White To Off-White SolidMasse moléculaire :453.331'-Epi 2',2'-Difluoro-2'-deoxyuridine
CAS :Applications The epimer of the degradation product of Gemcitabine (G305000), a new antitumor agent. References Anliker, S.L., et al.: J. Pharmaceut. Sci., 83, 716 (1994),Formule :C9H10F2N2O5Couleur et forme :Light Yellow SolidMasse moléculaire :264.186-Methylpterin
CAS :Produit contrôléApplications 6-Methylpterin is a derivative of Folic Acid (F680300) which is a precursor of coenzymes involved in metabolism of various nucleotides and nucleic acids. References Dantola, M.L. et al.: Photochem Photobiol Sci., 9, 1604 (2010);Formule :C7H7N5OCouleur et forme :NeatMasse moléculaire :177.16ent-Lamivudine
CAS :Enantiomer of LamivudineFormule :C8H11N3O3SDegré de pureté :Min. 95%Masse moléculaire :229.26 g/mol
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