Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
Produits appartenant à la catégorie "Nucléosides et Nucléotides"
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Cytidine 5'-monophosphate
CAS :Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide, one of the basic units that make up RNA.Formule :C9H14N3O8PDegré de pureté :99.10%Couleur et forme :SolidMasse moléculaire :323.2Uridine-2’,3’-Cyclic Monophosphate Sodium Salt
CAS :Formule :C9H10N2O8P·NaMasse moléculaire :305.16 22.99Dapagliflozin Impurity 7
CAS :Formule :C30H28Cl2O2Couleur et forme :White To Off-White SolidMasse moléculaire :491.45IDRA-21
CAS :IDRA-21 is a positive AMPA receptor modulator.Formule :C8H9ClN2O2SDegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :232.69(2RS)-2-Methylbutyl [1-(5-Deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate
CAS :Couleur et forme :NeatPyrrolo[1,2-f][1,2,4]triazin-4-amine
CAS :Pyrrolo[1,2-f][1,2,4]triazin-4-amine is a small molecule that inhibits the proliferation of leukemia cells as well as other tumor cells. It inhibits the replication of viruses in vitro and has been shown to inhibit the growth of viruses in cell culture. This compound also binds to phosphonates and can be used as an inhibitor in assays to measure phosphonate activity. Pyrrolo[1,2-f][1,2,4]triazin-4-amine has also been shown to have inhibitory properties against cancer cells in vivo and can be used to treat cancer. In addition, this compound reacts with hydroxyl groups by epimerization reactions and benzyl groups by substitution reactions.Formule :C6H6N4Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :134.14 g/molGanciclovir EP Impurity J
CAS :Produit contrôléFormule :C18H25N5O7Couleur et forme :NeatMasse moléculaire :423.42Galidesivir dihydrochloride
CAS :Galidesivir inhibits RdRP; has broad antiviral effects on various RNA viruses; effective against Ebola, Marburg in animals.Formule :C11H17Cl2N5O3Couleur et forme :SolidMasse moléculaire :338.191'-Epi gemcitabine 3',5'-dibenzoate
CAS :1'-Epi-Gemcitabine 3',5'-dibenzoate is an analytical standard that is used in the drug development process. It is also a high purity, API impurity, HPLC standard, and drug product. 1'-Epi-Gemcitabine 3',5'-dibenzoate is an impurity of Gemcitabine, which is an anticancer drug. The impurity can be found in the methanolic fraction of the extract and it's an epimer of Gemcitabine. The pharmacopoeia for this compound are USP and EP. Custom synthesis and natural or synthetic are possible for this compound.Formule :C23H19F2N3O6Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :471.41 g/molPenciclovir Impurity 2
CAS :Formule :C12H17N5O4Couleur et forme :White To Off-White SolidMasse moléculaire :295.30Fludarabine Phosphate
CAS :Fludarabine Phosphate (NSC 312887 Phosphate) is a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine with antineoplastic activity.Formule :C10H13FN5O7PDegré de pureté :98.26% - 99.25%Couleur et forme :SolidMasse moléculaire :365.21Ref: TM-T6501
5mg38,00€10mg57,00€25mg92,00€50mg115,00€100mg140,00€200mg190,00€500mg319,00€1mL*10mM (DMSO)55,00€Remdesivir Impurity 17
CAS :Formule :C27H35N6O8PCouleur et forme :White To Off-White SolidMasse moléculaire :602.58Zidovudine
CAS :Formule :C10H13N5O4Couleur et forme :White To Off-White SolidMasse moléculaire :267.25Sofosbuvir-13C-d3
CAS :Formule :C2113CH26D3FN3O9PCouleur et forme :White To Off-White SolidMasse moléculaire :533.47Valacyclovir Impurity 1
CAS :Formule :C12H14ClN5O4Couleur et forme :White To Off-White SolidMasse moléculaire :327.73Azacitidine Impurity 9
CAS :Formule :C10H14N4O6Couleur et forme :White To Off-White SolidMasse moléculaire :286.24Zidovudine
CAS :Zidovudine, a synthetic dideoxynucleoside, blocks DNA replication by inhibiting DNA polymerase after activation.Formule :C10H13N5O4Degré de pureté :99.84% - 99.91%Couleur et forme :White To Off-White CrystalsMasse moléculaire :267.24Sucrose
CAS :Cane or beet sugar and chemically pure sucrose, in solid form, refined, not containing added flavoring or coloring matter, nesoiFormule :C12H22O11Couleur et forme :Colorless White Crystalline PowderMasse moléculaire :342.11621Ribavirin Impurity 58
CAS :Formule :C3H3N3O2Couleur et forme :White To Off-White SolidMasse moléculaire :113.08Dapagliflozin
CAS :Formule :C21H25ClO6Couleur et forme :White To Off-White SolidMasse moléculaire :408.88L-Valine 2-hydroxyethyl ester tosylate
CAS :L-Valine 2-hydroxyethyl ester tosylate (L-V2HT) is a drug product that is synthesized by custom synthesis. It has high purity, analytical, and natural properties. L-V2HT is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The active form of L-V2HT is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. L-V2HT also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cellFormule :C14H23NO6SDegré de pureté :Min. 95%Masse moléculaire :333.4 g/mol3,5-Di-O-(4-chlorobenzoyl)-2-deoxy-a-D-ribofuranosyl isocyanate
3,5-Di-O-(4-chlorobenzoyl)-2-deoxy-a-D-ribofuranosyl isocyanate (CAS No. 53477) is a drug product that belongs to the class of drugs called nucleosides. 3,5-Di-O-(4-chlorobenzoyl)-2-deoxy-a-D-ribofuranosyl isocyanate has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. This product has been shown to have antiplasmodial activity and may be useful in the treatment of malaria.Formule :C20H15Cl2NO6Degré de pureté :Min. 95%Masse moléculaire :436.24 g/molEmtricitabine
CAS :Produit contrôléFormule :C8H10FN3O3SCouleur et forme :NeatMasse moléculaire :247.25Cidofovir Impurity 2 Disodium Salt
CAS :Formule :C8H11N2O7P·2NaCouleur et forme :White To Off-White SolidMasse moléculaire :278.16 2*22.99Dapagliflozin Impurity 22
CAS :Formule :C19H21ClO6Couleur et forme :White To Off-White SolidMasse moléculaire :380.82Azathioprine EP Impurity E Sodium Salt
CAS :Formule :C4H4N3O3·NaCouleur et forme :Light Yellow SolidMasse moléculaire :142.09 22.99Iso Ribavirin (Ribavirin Impurity G)
CAS :Produit contrôléFormule :C8H12N4O5Couleur et forme :NeatMasse moléculaire :244.2Fludarabine triphosphate
CAS :Fludarabine triphosphate inhibits key enzymes, causing cell death.Formule :C10H15FN5O13P3Couleur et forme :SolidMasse moléculaire :525.17Uridine triphosphate trisodium salt
CAS :Uridine triphosphate trisodium salt (UTP, Trisodium Salt) is a nucleotide.Formule :C9H12N2Na3O15P3Degré de pureté :100.00% - 99.83%Couleur et forme :White PowderMasse moléculaire :550.09Decitabine Impurity 2 (α-Isomer)
CAS :Formule :C22H24O6Couleur et forme :White To Off-White SolidMasse moléculaire :384.43Ganciclovir Triacetate
CAS :Formule :C15H19N5O7Couleur et forme :Pale Yellow SolidMasse moléculaire :381.35Adefovir diphosphate
CAS :Adefovir monophosphate: antiviral ANP active against HBV, herpes; ntRTI for hepatitis B, not HIV-1 effective.Formule :C8H13N5O7P2Couleur et forme :SolidMasse moléculaire :353.17Remdesivir impurity 3 HCl
CAS :Remdesivir impurity 3 HCl is a drug product that is a metabolite of Remdesivir. It has been shown to be a natural, synthetic and research and development impurity standard for HPLC analysis. CAS No.: 2096981-79-0Formule :C9H19NO2·HClDegré de pureté :Min. 95%Masse moléculaire :209.71 g/molAdenosine-3’,5’-cyclic Monophosphate
CAS :Stability Hygroscopic Applications Adenosine-3’,5’-cyclic Monophosphate is an Adenosine (A280400) derivative useful as anticancer agent. References Keast, R., et al.: Pharma. Res., 19, 1019 (2002),Formule :C10H12N5O6PCouleur et forme :NeatMasse moléculaire :329.21Decitabine Impurity 50 (Deformyl Impurity) Formate (Mixture of Diastereomers)
CAS :Formule :C7H14N4O4·CH2O2Couleur et forme :White To Off-White SolidMasse moléculaire :218.21 46.03Stavudine
CAS :Produit contrôléImpurity Zidovudine EP Impurity A Applications Stavudine (Zidovudine EP Impurity A) is used as an antiviral. A reverse transcriptase inhibitor. References Mansuri, M.M., et al.: Antimicrob. Ag. Chemother., 34, 637 (1990), Cretton, E.M., et al.: Antimicrob. Ag. Chemother., 37, 1816 (1993), Browne, M.J., et al.: J. Infec. Dis., 167, 21 (1993)Formule :C10H12N2O4Couleur et forme :WhiteMasse moléculaire :224.21Entecavir Impurity 13
Formule :C32H33N5O4Couleur et forme :White To Off-White SolidMasse moléculaire :551.65Methylcobalamin Hydrate
CAS :Formule :C63H91CoN13O14P·xH2OCouleur et forme :White To Off-White SolidMasse moléculaire :1344.41 18.02Thiamine pyrophosphate chloride
CAS :Thiamine pyrophosphate, a vitamin B1 derivative, is a coenzyme in transketolase studies for decarboxylation in biology.Formule :C12H19ClN4O7P2SDegré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :460.76Cladribine EP Impurity D
CAS :Formule :C10H12ClN5O3Couleur et forme :White To Off-White SolidMasse moléculaire :285.69Lamivudine Impurity 3
Formule :C18H27N3O4SCouleur et forme :White To Off-White SolidMasse moléculaire :381.49Valaciclovir EP Impurity M (Valacyclovir USP Related Compound M)
CAS :Formule :C14H20N6O5Couleur et forme :White To Off-White SolidMasse moléculaire :352.35Fosamprenavir Enantiomer
Formule :C25H36N3O9PSCouleur et forme :White To Off-White SolidMasse moléculaire :585.61Ribavirin EP Impurity C
CAS :Formule :C3H3N3O2Couleur et forme :White To Off-White SolidMasse moléculaire :113.08Melphalan Impurity 1
CAS :Formule :C9H10N2O4Couleur et forme :Off-White SolidMasse moléculaire :210.19Folinic Acid EP Impurity G Disodium Salt (7,8-Dihydrofolic Acid Disodium Salt)
CAS :Formule :C19H19N7O6·2NaCouleur et forme :Orange-Yellow SolidMasse moléculaire :441.42 2*22.99Sulfosate
CAS :Formule :C3H7NO5P·C3H9SCouleur et forme :Off-White Semi-SolidMasse moléculaire :168.07 77.16Brivudine Impurity 1 ((E)-5-(2-Bromovinyl)uracil)
CAS :Formule :C6H5BrN2O2Couleur et forme :Pale Yellow SolidMasse moléculaire :217.02APX-115 free base
CAS :APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μMFormule :C17H17N3ODegré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :279.34Ref: TM-T10353
1mg49,00€5mg97,00€10mg160,00€25mg329,00€50mg533,00€100mg822,00€200mg1.130,00€1mL*10mM (DMSO)123,00€Calcium Levomefolate (L-5-Methyltetrahydrofolate Calcium Salt)
CAS :Formule :C20H23N7O6·CaCouleur et forme :Pale Yellow SolidMasse moléculaire :457.45 40.081’-Epi Gemcitabine Hydrochloride
CAS :Impurity Gemcitabine EP Impurity B Applications 1’-Epi Gemcitabine Hydrochloride (Gemcitabine EP Impurity B) is an α-Anomer of Gemcitabine. References Hertel, L.W., et al.: Cancer Res., 50, 4417 (1990), Abbruzzese, J.L., et al.: J. Clin. Oncol., 9, 491 (1991), Ruiz, V.W.T., et al.: Biochem. Pharmacol., 46, 762 (1993),Formule :C9H12ClF2N3O4Couleur et forme :Off White SolidMasse moléculaire :299.66Decarboxylated S-Adenosylmethionine-13C-d3 Sulfate Salt
CAS :Formule :C1313CH20D3N6O3S·HSO4H2SO4Masse moléculaire :359.45 97.06 98.07Peramivir Impurity 1
CAS :Formule :C18H30N2O5Couleur et forme :Off-White SolidMasse moléculaire :354.45Favipiravir Impurity 6
CAS :Formule :C5H2FN3Couleur et forme :White To Off-White SolidMasse moléculaire :123.09Decitabine Impurity 54 Triethylamine Salt
CAS :Formule :C8H13N4O7P·xC6H15NCouleur et forme :White To Off-White SolidMasse moléculaire :308.19 x*101.19rac-Melphalan EP Impurity I HCl
CAS :Formule :C14H21ClN2O3·HClCouleur et forme :White To Off-White SolidMasse moléculaire :300.78 36.46Sofosbuvir impurity 6
CAS :Sofosbuvir impurity 6 is an impurity in the drug Sofosbuvir. It is a metabolite that is a by-product of the synthesis process of Sofosbuvir, which is used to treat chronic hepatitis C infection. The purity of this compound has been tested with HPLC and found to be 99.99% pure. This compound can also be synthesized from natural or synthetic sources.Formule :C31H27N3O7Degré de pureté :Min. 95%Masse moléculaire :553.56 g/molCytarabine Impurity 3
CAS :Formule :C17H19N5O8Couleur et forme :White To Off-White SolidMasse moléculaire :421.371’-epi-Entecavir
CAS :Produit contrôléImpurity Entecavir EP Impurity A Applications An epimeric impurity of the antiviral drug Entecavir (E558900).Formule :C12H15N5O3Couleur et forme :NeatMasse moléculaire :277.279Entecavir Impurity 6 (ent-Entecavir-di-O-benzyl Ether)
CAS :Formule :C26H27N5O3Couleur et forme :White To Off-White SolidMasse moléculaire :457.53Viaminate
CAS :Viaminate, a derivative of retinoic acid, is utilized in the treatment of severe acne and other keratinization disorders.Formule :C29H37NO3Couleur et forme :SolidMasse moléculaire :447.61Adenosine-5',5''-d2
CAS :Produit contrôléApplications Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes. References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)Formule :C10H11D2N5O4Couleur et forme :White SolidMasse moléculaire :269.26Ribavirin Impurity 53 (D-Ribose) (Mixture of Diastereomers)
CAS :Formule :C5H10O5Masse moléculaire :150.13Capecitabine EP Impurity C
CAS :Formule :C13H16FN3O6Couleur et forme :White To Off-White SolidMasse moléculaire :329.28Ribavirin EP Impurity B
CAS :Formule :C8H12N4O5Couleur et forme :White To Off-White SolidMasse moléculaire :244.21Emtricitabine-13C,15N2
CAS :Produit contrôléStability Very Hygroscopic Applications Labelled Emtricitabine. A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500). References Schinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. Infec. Dis., 182, 599 (2000)Formule :CC7H10FN2NO3SCouleur et forme :White To Light YellowMasse moléculaire :250.23Peramivir Impurity 3
CAS :Formule :C18H30N2O5Couleur et forme :White To Off-White SolidMasse moléculaire :354.45Uridine triphosphate
CAS :Uridine triphosphate (Uridine 5'-triphosphate) increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.Formule :C9H15N2O15P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.143’-O-(5’-Deoxy-α-D-ribofuranosyl) Capecitabine
CAS :Produit contrôléApplications Capecitabine (C175650) impurity.Formule :C20H30FN3O9Couleur et forme :NeatMasse moléculaire :475.47Thymidine
CAS :Thymidine (DThyd) is a cell synchronizing agent and a precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis. Cost-effective and quality-assured.Formule :C10H14N2O5Degré de pureté :99.27% - ≥95%Couleur et forme :White To Off-White Solid CrystallineMasse moléculaire :242.23
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