Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
Produits appartenant à la catégorie "Nucléosides et Nucléotides"
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Zanamivir
CAS :Formule :C12H20N4O7Couleur et forme :White To Off-White SolidMasse moléculaire :332.324’-Epi Lamivudine
CAS :Produit contrôléApplications Lamivudine epimer. References Chang, C., et al.: J. Biol. Chem., 267, 13938 (1992), Jeong, L., et al.: J. Med. Chem., 36, 181 (1993),Formule :C8H11N3O3SCouleur et forme :NeatMasse moléculaire :229.26Sofosbuvir impurity 2
CAS :Sofosbuvir impurity 2 is a synthetic compound that is used as an impurity standard for the HPLC assay of sofosbuvir. It is a white to off-white crystalline solid at room temperature.Formule :C22H29ClN3O9PDegré de pureté :Min. 95%Masse moléculaire :545.91 g/molOxiracetam Related Compound 4
CAS :Formule :C4H9N3O2Couleur et forme :White To Off-White SolidMasse moléculaire :131.14Cangrelor Impurity 7 (Mixture of Diastereomers)
Formule :C16H22F3N5O5S2Couleur et forme :White To Off-White SolidMasse moléculaire :485.50Dapagliflozin Impurity 6
CAS :Formule :C15H12BrClO2Couleur et forme :White To Off-White SolidMasse moléculaire :339.61Isoribavirin
CAS :Isoribavirin is a ribonucleoside monophosphate analog that inhibits viral RNA polymerase. Isoribavirin has been shown to be active against influenza virus, herpes simplex virus, and vesicular stomatitis virus in cell culture. Isoribavirin is stable in an acetonitrile solution in the presence of phosphoric acid at pH 3-4 or in the presence of sulfate ions at pH 9-10. It can be purified by chromatography on a silica gel column using an acetonitrile/water mobile phase gradient. The impurities of isoribavirin are not detectable by liquid chromatography and have no significant effect on its sensitivity. Isoribavirin elutes from the silica gel column with the impurities.Formule :C8H12N4O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :244.21 g/molalfa-Adenosine
CAS :Formule :C10H13N5O4Couleur et forme :White To Off-White SolidMasse moléculaire :267.252-Deoxy-3,5-di-O-p-toluoyl-a-L-ribofuranosyl Chloride
CAS :Stability Moisture Sensitive, Unstable in Solution Applications 2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl Chloride (cas# 141846-57-3) is a compound useful in organic synthesis.Formule :C21H21ClO5Couleur et forme :NeatMasse moléculaire :388.84Brivudine monophosphate
CAS :Brivudine monophosphate, a phosphate ester, inhibits DNA repair, induces apoptosis, and may downregulate STAT3 and chemoresistance genes.Formule :C11H14BrN2O8PCouleur et forme :SolidMasse moléculaire :413.12Emtricitabine Impurity 11
CAS :Formule :C10H20OCouleur et forme :Pale Yellow LiquidMasse moléculaire :156.27Molnupiravir Impurity 1
CAS :Formule :C9H13N3O6Couleur et forme :White To Off-White SolidMasse moléculaire :259.22Stavudine
CAS :Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.Formule :C10H12N2O4Degré de pureté :100% - 99.74%Couleur et forme :White PowderMasse moléculaire :224.21Adenosine A1 receptor activator T62
CAS :Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and alsoFormule :C15H14ClNOSDegré de pureté :97.83%Couleur et forme :SolidMasse moléculaire :291.8Ref: TM-T14127
1mg87,00€5mg183,00€10mg273,00€25mg439,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)280,00€Tegafur
CAS :Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity.Formule :C8H9FN2O3Degré de pureté :99.16% - 99.89%Couleur et forme :White Crystalline PowderMasse moléculaire :200.17Adefovir Dipivoxil Impurity 10 (Mono-POM Methyl Adefovir)
CAS :Formule :C15H24N5O6PCouleur et forme :White To Off-White SolidMasse moléculaire :401.36(R,S)-Adenosyl-L-Methionine Di-1,4-Butanedisulfonate
Formule :C15H22N6O5S·2C4H10O6S2Masse moléculaire :398.44 2*218.24Peramivir Impurity 40
CAS :Formule :C14H24N2O3Couleur et forme :White To Off-White SolidMasse moléculaire :268.36Uridine 5'-diphosphate Disodium Salt
CAS :Formule :C9H12N2O12P2·2NaCouleur et forme :Off-White SolidMasse moléculaire :402.15 2 22.99Cytidine 5'-Monophosphomorpholidate 4-Morpholine-N,N'-dicyclohexylcarboxamidine Salt
CAS :Formule :C18H32N2O·C13H20N4O8PMasse moléculaire :292.47 391.30Cytarabine EP Impurity F
CAS :Formule :C9H11N3O4Couleur et forme :Off-White SolidMasse moléculaire :225.20Molnupiravir Impurity 11
CAS :Formule :C16H23N3O7Couleur et forme :White To Off-White SolidMasse moléculaire :369.37Decitabine Impurity 3
CAS :Formule :C21H22O6Couleur et forme :White To Off-White SolidMasse moléculaire :370.41Galidesivir
CAS :Galidesivir (BCX4430) is an antiviral compound that inhibits viral RNA-dependent RNA polymerase (RdRp) activity and reduces lung infections in infected animals.Formule :C11H15N5O3Degré de pureté :96.73% - 99.13%Couleur et forme :SolidMasse moléculaire :265.27Dapagliflozin Impurity 17
CAS :Formule :C15H14Br2OCouleur et forme :White To Off-White SolidMasse moléculaire :370.08VAS2870
CAS :VAS2870 is an inhibitor of NADPH oxidase (NOX).Formule :C18H12N6OSDegré de pureté :97.49%Couleur et forme :SolidMasse moléculaire :360.39Bucladesine Sodium Salt
CAS :Formule :C18H23N5O8P·NaCouleur et forme :White To Off-White SolidMasse moléculaire :468.39 22.99Valacyclovir hydrochloride
CAS :Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an acyclovir prodrug that inhibits viral DNA replication after metabolization.Formule :C13H20N6O4·HClDegré de pureté :100% - ≥95%Couleur et forme :White To Off-White Crystalline PowerMasse moléculaire :360.8Ref: TM-T1087
1g299,00€10mg47,00€25mg69,00€50mg85,00€100mg97,00€200mg127,00€500mg202,00€1mL*10mM (DMSO)47,00€Pteroic acid - 60%
CAS :Purity min. 60%Formule :C14H12N6O3Degré de pureté :Min. 93 Area-%Couleur et forme :PowderMasse moléculaire :312.28 g/molCladribine EP Impurity B
CAS :Formule :C11H15N5O4Couleur et forme :White To Off-White SolidMasse moléculaire :281.27Molnupiravir Impurity 4
CAS :Formule :C9H13N3O6Couleur et forme :White To Off-White SolidMasse moléculaire :259.22Adenosine 5'-Monophosphate-13C5
CAS :Stability Hygroscopic Applications Labelled Adenosine 5’-Monophosphate (A281790), a naturally occurring nucleotide. A useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists. References Hong, J.A. et al.: J. Med. Chem., 52, 5485 (2009); Korboukh I. et al.: J. Med. Chem., 55, 6467 (2012)Formule :C513C5H14N5O7PCouleur et forme :White To Off-WhiteMasse moléculaire :352.18Dapagliflozin Impurity 11
Formule :C42H48Cl2O12Couleur et forme :White To Off-White SolidMasse moléculaire :815.73Cidofovir dihydrate
CAS :Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.Formule :C8H18N3O8PDegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :315.22Brivudine-13C4-15N2
CAS :Formule :C415N2C7H13BrOCouleur et forme :Pale Yellow SolidMasse moléculaire :339.08Bucladesine Impurity 2 Tetrabutylammonium Salt
CAS :Formule :C14H17N5O7P·C16H36NMasse moléculaire :398.29 242.47Gemcitabine EP Impurity C
CAS :Formule :C9H10F2N2O5Couleur et forme :White To Off-White SolidMasse moléculaire :264.18ARL67156 trisodium salt
CAS :ARL 67156 inhibits NTPDase1, 3, NPP1 (Ki: 11, 18, 12 μM) and ecto-ATPase; it's a trisodium salt.Formule :C15H21Br2N5Na3O12P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :785.05Stearic Acid
CAS :Palmitic acid, stearic acid, their salts and estrsFormule :C18H36O2Couleur et forme :White Light Yellow PowderMasse moléculaire :284.27153Desciclovir
CAS :Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.Formule :C8H11N5O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :209.21Ref: TM-T22304
1mg64,00€2mg86,00€5mg116,00€10mg170,00€25mg313,00€50mg472,00€100mg702,00€200mg944,00€1mL*10mM (DMSO)111,00€Decarboxylated (S)-Adenosyl Methionine Trifluoromethanesulfonic Acid
CAS :Formule :C14H23N6O3S·CF3O3SCouleur et forme :Orange SolidMasse moléculaire :355.44 149.06(Z)-Viaminate
CAS :(Z)-Viaminate is a derivative of Retinoic acid.Formule :C29H37NO3Couleur et forme :SolidMasse moléculaire :447.61Oxiracetam Impurity 1 Sodium Salt
CAS :Formule :C6H8NO4·NaCouleur et forme :Yellow SolidMasse moléculaire :158.13 22.99Nelarabine Impurity 4
CAS :Formule :C11H14N4O6Couleur et forme :White To Off-White SolidMasse moléculaire :298.26Emtricitabine impurity 17
CAS :Please enquire for more information about Emtricitabine impurity 17 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C8H10FN3O4SDegré de pureté :Min. 95%Masse moléculaire :263.24 g/molBictegravir
CAS :Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM).Formule :C21H18F3N3O5Degré de pureté :97.6% - 99.51%Couleur et forme :SolidMasse moléculaire :449.38Ref: TM-T4493
1mg50,00€5mg66,00€10mg96,00€25mg185,00€50mg311,00€100mg469,00€500mg1.064,00€1mL*10mM (DMSO)66,00€Uridine Diphosphate Choline (UDPC)
CAS :Formule :C14H25N3O12P2Couleur et forme :White To Off-White SolidMasse moléculaire :488.312'-Epi-lamivudine
CAS :2'-Epi-lamivudine is a chiral, racemic mixture of the two enantiomers of lamivudine. The synthesis and purification of 2'-epi-lamivudine is achieved by using a chiralpak column to separate the optical isomers from each other and then an immunoaffinity column to remove the undesired enantiomer (the S-enantiomer). The final product is a mixture of both enantiomers in a 1:1 ratio, which has been shown to have antiviral activity against HIV. 2'-Epi-lamivudine has been shown to be more potent than its parent compound lamivudine and is less toxic. This antiviral agent inhibits HIV replication by inhibiting reverse transcriptase, which is an enzyme that synthesizes viral DNA from viral RNA. It also has anti-inflammatory properties that may be due to inhibition of prostaglandin synthesis.Formule :C8H11N3O3SDegré de pureté :Min. 95%Masse moléculaire :229.26 g/molEmtricitabine Impurity 16 Disodium Salt
CAS :Formule :C18H22FN8O7PS·2NaCouleur et forme :White To Off-White SolidMasse moléculaire :544.46 2*22.99Zalcitabine
CAS :Zalcitabine (ddC) is a nucleoside analog inhibiting HIV by blocking reverse transcriptase and halting viral DNA synthesis.Formule :C9H13N3O3Degré de pureté :99.73% - ≥95%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :211.22Cladribine
CAS :Formule :C10H12ClN5O3Couleur et forme :White To Off-White SolidMasse moléculaire :285.69Cytidine 5’-Monophosphate Ethyl Ester Sodium
CAS :Formule :C11H17N3O8P·NaMasse moléculaire :350.24 22.99Vitamin B6 Impurity 1
CAS :Formule :C8H14O2Couleur et forme :Colorless LiquidMasse moléculaire :142.20Capecitabine EP Impurity D
CAS :Formule :C15H22FN3O6Couleur et forme :White To Off-White SolidMasse moléculaire :359.35Capecitabine Impurity 12
Formule :C11H16O7Couleur et forme :White To Off-White SolidMasse moléculaire :260.24Cordycepin
CAS :Cordycepin (3'-Deoxyadenosine) is a purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplasticFormule :C10H13N5O3Degré de pureté :100% - 99.78%Couleur et forme :Crystalline SolidMasse moléculaire :251.24Cytarabine EP Impurity A
CAS :Produit contrôléFormule :C9H12N2O6Couleur et forme :NeatMasse moléculaire :244.20Folic Acid EP Impurity F
CAS :Formule :C7H6ClN5OCouleur et forme :Yellow SolidMasse moléculaire :211.61Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-a-D-glucopyranoside
CAS :Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-alpha-D-glucopyranoside is an impurity of Dapagliflozin.Formule :C22H27ClO7Degré de pureté :Min. 95%Masse moléculaire :438.9 g/molLevovirin
CAS :Produit contrôléLevovirin is an antiviral agent that belongs to the class of ribonucleotide reductase inhibitors. It is a potent inhibitor of hepatitis C virus replication and has been shown to be active against HIV in vitro. Levovirin acts as a competitive inhibitor of the NS3 protease, which is responsible for processing viral proteins. This inhibition prevents the production of new virus particles and the spread of infection. Levovirin also has immunomodulatory effects, which may provide therapeutic benefits in autoimmune diseases such as rheumatoid arthritis or Crohn's disease.Formule :C8H12N4O5Degré de pureté :Min. 95%Masse moléculaire :244.2 g/molN1-Nitroso Folinic Acid (N1-Nitroso Folic Acid USP Related Compound A, N1-Nitroso Leucovorin)
CAS :Formule :C20H22N8O8Masse moléculaire :502.44Ademethionine 1,4-Butanedisulfonate
CAS :Formule :C15H23N6O5S·n4H10O6S2·5C4H8O6S2Couleur et forme :White To Off-White SolidMasse moléculaire :399.45 n*218.25 0.5*216.23Cytidine Related Compound 4
CAS :Formule :C41H49N4O9PCouleur et forme :White To Off-White SolidMasse moléculaire :772.84Ribavirin Impurity 31
CAS :Formule :C15H19N3O9Couleur et forme :White To Off-White SolidMasse moléculaire :385.33Nucleocidin
CAS :Nucleocidin, an antitrypanosomal antibiotic, inhibits the transfer of labeled amino acids from S-RNA to protein.Formule :C10H13FN6O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :364.311-C-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol
CAS :Produit contrôléApplications Open ring Dapagliflozin. Dapagliflozin (D185370) impurity.Formule :C21H27ClO7Couleur et forme :NeatMasse moléculaire :426.888Adenosine-3',5'-cyclic-13C5 Monophosphate
CAS :Stability Hygroscopic Applications Labelled Adenosine-3’,5’-cyclic Monophosphate (A280455). Adenosine-3’,5’-cyclic Monophosphate is an Adenosine (A280400) derivative useful as anticancer agent. References Keast, R., et al.: Pharma. Res., 19, 1019 (2002),Formule :C5C5H12N5O6PCouleur et forme :NeatMasse moléculaire :334.1692Zidovudine EP Impurity G
CAS :Formule :C20H25N7O8Couleur et forme :White To Off-White SolidMasse moléculaire :491.463’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine
CAS :Produit contrôléImpurity Capecitabine 3-O-BDR Impurity (USP) Applications Capecitabine (C175650) impurity. Capecitabine 3-O-BDR Impurity (USP).Formule :C20H30FN3O9Couleur et forme :NeatMasse moléculaire :475.47Clofarabine
CAS :Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotideFormule :C10H11ClFN5O3Degré de pureté :100% - 99.94%Couleur et forme :White SolidMasse moléculaire :303.68Ref: TM-T0297
5mg43,00€10mg59,00€25mg95,00€50mg133,00€100mg172,00€200mg215,00€500mg360,00€1mL*10mM (DMSO)55,00€Adenosine 2',3'-Cyclic Phosphate-13C5 Triethylammonium Salt
CAS :Produit contrôléApplications A labelled 2',3'-cyclic nucleotide phosphodiester References Voegtli, W., et al.: Biochemistry, 39, 15365 (2000), Bernstein, N., et al.: Mol. Cell, 17, 657 (2005), Blondal, T., et al.: J. Biol. Chem., 280, 5188 (2005), Shenoy, A., et al.: J. Mol. Biol., 365, 211 (2007),Formule :C1113C5H27N6O6PCouleur et forme :NeatMasse moléculaire :435.36Vitamin B6 Impurity 14 Sodium Salt
CAS :Formule :C7H8NO4·NaCouleur et forme :White To Off-White SolidMasse moléculaire :170.14 22.99L-Tetrahydrofolic Acid-d4 (Major) (>70% when packaged)
CAS :Produit contrôléApplications L-Tetrahydrofolic Acid-d4 (Major) is a folic acid derivative and coenzyme involved in the metabolism of amino and nucleic acids. References Prinz-Langenohl, R., et al.: Brit. J. Pharmacol., 158, 2014 (2009), Martin, H., et al.: Anal. Biochem., 402, 137 (2010), Dasarathy, J., et al.: Am. J. Clin. Nut., 91, 357 (2010), Karas-Kuzelicki, N., et al.: Clin. Biochem., 43, 37 (2010),Formule :C19H19D4N7O6Couleur et forme :Light BrownMasse moléculaire :449.45Dapagliflozin Impurity 15
CAS :Formule :C15H14BrClOCouleur et forme :White To Off-White SolidMasse moléculaire :325.63
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