Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
Produits appartenant à la catégorie "Nucléosides et Nucléotides"
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Cladribine
CAS :Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.Formule :C10H12ClN5O3Degré de pureté :100% - 99.99%Couleur et forme :White Crystalline SolidMasse moléculaire :285.69Canagliflozin Impurity 18 (Mixture of Diastereomers)
CAS :Formule :C24H25FO6SCouleur et forme :White To Off-White SolidMasse moléculaire :460.52Azacitidine Impurity 17
CAS :Formule :C8H12N4O5Couleur et forme :Off-White SolidMasse moléculaire :244.21Remdesivir Impurity 19
CAS :Formule :C6H6N4Couleur et forme :Light Brown SolidMasse moléculaire :134.14Azacitidine USP Related Compound B
CAS :Produit contrôléFormule :C28H24O9Couleur et forme :NeatMasse moléculaire :504.48Floxuridine
CAS :Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.Formule :C9H11FN2O5Degré de pureté :98.92% - 99.96%Couleur et forme :SolidMasse moléculaire :246.19Azacitidine USP Related Compound C (Free Base)
CAS :Formule :C7H14N4O5Couleur et forme :Off-White SolidMasse moléculaire :234.21Entecavir EP Impurity B HCl
CAS :Formule :C12H15N5O3·HClCouleur et forme :White To Off-White SolidMasse moléculaire :277.29 36.461-(5-O-Benzoyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide (5'-O-Benzoylribavirin)
CAS :Produit contrôléFormule :C15H16N4O6Couleur et forme :NeatMasse moléculaire :348.31Dapagliflozin
CAS :Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.Formule :C21H25ClO6Degré de pureté :99.5% - 99.74%Couleur et forme :SolidMasse moléculaire :408.87Levofolinic Acid
CAS :Formule :C20H23N7O7Couleur et forme :Pale Yellow SolidMasse moléculaire :473.45Dextrose
CAS :Glucose (dextrose)Formule :C6H12O6Couleur et forme :Colorless White Crystalline Powder GranularMasse moléculaire :180.2Entecavir Impurity 12
Formule :C32H33N5O4Couleur et forme :White To Off-White SolidMasse moléculaire :551.65Chlorotrianisene
CAS :Chlorotrianisene, a synthetic SERM, is orally active, lipophilic, and has estrogenic and antiestrogenic effects.Formule :C23H21ClO3Degré de pureté :98.88% - 99.03%Couleur et forme :Crystals From Methanol Physical Description Small White Crystals Or White Powder Softens At 226°F Odorless (Ntp 1992)Masse moléculaire :380.86Ref: TM-T2569
1mg59,00€5mg127,00€10mg205,00€25mg344,00€50mg512,00€100mg730,00€200mg998,00€1mL*10mM (DMSO)139,00€Ganciclovir Monoacetate
CAS :Formule :C11H15N5O5Couleur et forme :White To Off-White SolidMasse moléculaire :297.27Cladribine Related Compound A (2-methoxy-2'-deoxyadenosine)
CAS :Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormule :C11H15N5O4Couleur et forme :White Off-White Crystalline PowderMasse moléculaire :281.1124Peramivir Impurity 28
CAS :Formule :C12H19NO4Couleur et forme :White To Off-White SolidMasse moléculaire :241.29Emtricitabine Tenofovir Disoproxil Dimer
CAS :Formule :C28H40FN8O13PSCouleur et forme :White To Off-White SolidMasse moléculaire :778.70Emtricitabine N,N’-Methylene Dimer
Produit contrôléApplications Emtricitabine N,N’-Methylene Dimer is a derivative compound of Emtricitabine (E525000), a reverse transcriptase inhibitor. It is effective antiviral agent against HIV, and other viruses replicating in a similiar manner. A nucleoside analog structurally related to Lamivudine (L172500). References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)Formule :C17H20F2N6O6S2Couleur et forme :NeatMasse moléculaire :506.5(R)-Oxiracetam
CAS :(R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam. Oxiracetam is a nootropic drug of the racetam family and stimulant.Formule :C6H10N2O3Couleur et forme :SolidMasse moléculaire :158.16Adenosine 5'-diphosphate
CAS :Adenosine 5'-diphosphate (ADP) is a natural nucleotide derived from the dephosphorylation of ATP. ADP induces platelet aggregation. Cost effective and quality assured.Formule :C10H15N5O10P2Degré de pureté :100% - 99.81%Couleur et forme :SolidMasse moléculaire :427.2Ganciclovir
CAS :Formule :C9H13N5O4Couleur et forme :White To Off-White SolidMasse moléculaire :255.23LY450108
CAS :LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.Formule :C19H22F2N2O3SDegré de pureté :100% - 98.8%Couleur et forme :SolidMasse moléculaire :396.45Ref: TM-TQ0289
2mg39,00€5mg58,00€10mg94,00€25mg145,00€50mg212,00€100mg295,00€200mg470,00€1mL*10mM (DMSO)65,00€AKR1C3-IN-9
AKR1C3-IN-9: Selective AKR1C3 inhibitor, IC50=8.92 nM; reverses DOX resistance in breast cancer.Formule :C20H20N2O4Degré de pureté :99.41%Couleur et forme :SoildMasse moléculaire :352.38Ref: TM-T67846
5mg46,00€10mg64,00€25mg116,00€50mg187,00€100mg306,00€200mg442,00€1mL*10mM (DMSO)49,00€Ganciclovir triphosphate
CAS :Ganciclovir triphosphate: synthetic 2'-deoxy-guanosine analog, treats/prevents CMV, IC50 of 0.01 μM, effective across species.Formule :C9H16N5O13P3Couleur et forme :SolidMasse moléculaire :495.17cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione
CAS :cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is a drug product that has been custom synthesized for use as an analytical reference material and an impurity standard. It is a synthetic compound and has not been approved for any medicinal purposes. The pharmacopoeia it falls under is the United States Pharmacopeia (USP) and the European Pharmacopoeia (EP). cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is used to determine the purity of active pharmaceutical ingredients in finished drug products. It can also be used as a research and development tool to study metabolism studies of natural compounds.Formule :C8H9FN2O4SDegré de pureté :Min. 95%Masse moléculaire :248.23 g/molFolic acid
CAS :Folic acid (Vitamin B9) is a vitamin B9 that is essential for the synthesis of DNA/RNA and for the production new cells. Cost-effective and quality-assured.Formule :C19H19N7O6Degré de pureté :99.19% - 99.27%Couleur et forme :Yellowish-Orange Crystals; Extremely Thin Platelets (Elongated @ 2 Ends) From Hot Water 482°FMasse moléculaire :441.4Uridine Impurity 2 (Pseudouridine)
CAS :Formule :C9H12N2O6Couleur et forme :White To Off-White SolidMasse moléculaire :244.20RO 2433
CAS :Produit contrôléImpurity Sofosbuvir Metabolite GS331007 Applications RO 2433 is the deaminated metabolite of β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) replication in vitro. References Asif, G., et. al.: Antimicrob. Agents Ch., 51, 2877 (2007)Formule :C10H13FN2O5Couleur et forme :NeatMasse moléculaire :260.22Uridine
CAS :Uridine (Uridin) is a nucleoside compound, a base that makes up RNA, that replaces thymine in DNA during transcriptione. Cost-effective and quality-assured.Formule :C9H12N2O6Degré de pureté :99.08% - 99.63%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :244.2Folinic Acid EP Impurity D Disodium Salt
CAS :Formule :C20H17N7O7·2NaMasse moléculaire :467.40 2*22.99Creatinine-d3
CAS :Formule :C4H4D3N3OCouleur et forme :White To Off-White SolidMasse moléculaire :116.14Entecavir Impurity 51
CAS :Formule :C51H45N5O4Couleur et forme :Off-White SolidMasse moléculaire :791.95Ubidecarenone (Coenzyme Q10) EP Impurity B (Mixture of Isomers)
CAS :Formule :C44H66O4Couleur et forme :Orange OilMasse moléculaire :659.01Thymidine (Zidovudine EP Impurity E, Zidovudine USP Related Compound D)
CAS :Formule :C10H14N2O5Masse moléculaire :242.23Gemcitabine EP Impurity C-13C-15N2
CAS :Formule :C813CH10F215N2O5Couleur et forme :White To Off-White SolidMasse moléculaire :267.162-Aminopurine
CAS :2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.Formule :C5H5N5Degré de pureté :99.51%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :135.13ES 936
CAS :ES 936 is a potent and selective NQO1 inhibitor, inhibiting more than 95% of NQO1 100 nM, with a cell line-dependent inhibition duration.Formule :C18H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.33Dapagliflozin Propanediol
CAS :Formule :C21H25ClO6·C3H8O2Couleur et forme :White To Off-White SolidMasse moléculaire :408.88 76.102-[2-(2-Amino-9H-purin-9-yl)ethyl]propane-1,3-diol Hydrochloride
CAS :Produit contrôléFormule :C10H15N5O2·ClHCouleur et forme :NeatMasse moléculaire :273.721'-Epi gemcitabine, hydrochloride
CAS :Gemcitabine hydrochloride is an analog of the natural nucleoside cytidine. It is a chemotherapeutic drug that is used in the treatment of pancreatic, lung and breast cancer. Gemcitabine hydrochloride is metabolized to its active form by deamination of cytosine residues in DNA. This conversion is catalyzed by the enzyme cytidine deaminase. Gemcitabine hydrochloride has been shown to be effective against metastatic pancreatic cancer and advanced-stage non-small cell lung cancer, as well as early-stage breast cancer. Gemcitabine hydrochloride has also been shown to be effective against certain types of lymphoma and leukemia.Formule :C9H12ClF2N3O4Degré de pureté :Min. 95%Masse moléculaire :299.66 g/molCytidine 5'-Monophosphate Disodium Salt
CAS :Formule :C9H12N3O8P·2NaCouleur et forme :White To Off-White SolidMasse moléculaire :321.19 2*22.99Fludarabine
CAS :Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation.Formule :C10H12FN5O4Degré de pureté :100% - 99.88%Couleur et forme :White SolidMasse moléculaire :285.23Sofosbuvir Impurity 2
CAS :Formule :C31H27N3O8Couleur et forme :White To Off-White SolidMasse moléculaire :569.58Molnupiravir
CAS :Formule :C13H19N3O7Couleur et forme :White To Off-White SolidMasse moléculaire :329.31Sofosbuvir Impurity 40
CAS :Formule :C16H18FN2O8PCouleur et forme :White To Off-White SolidMasse moléculaire :416.30Uridine-3’,5’-Cyclic Monophosphate Tetrabutylammonium Salt
CAS :Formule :C9H10N2O8P·C16H36NMasse moléculaire :305.16 242.47Cyclopropyl Diaminopurine Abacavir
CAS :Formule :C8H10N6Couleur et forme :Off-White SolidMasse moléculaire :190.215’-O-[Bis(4-methoxyphenyl)phenylmethyl]-2’-deoxy-N-ethylcytidine
CAS :Formule :C32H35N3O6Masse moléculaire :557.652’-Deoxyadenosine
CAS :Applications 2prime-Deoxyadenosine is a nucleoside adenosine derivative with mutagenic properties.Formule :C10H13N5O3Couleur et forme :White To Off-WhiteMasse moléculaire :251.2425-Fluorouracil
CAS :5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis.Formule :C4H3FN2O2Degré de pureté :100% - 99.98%Couleur et forme :White To Practically White Crystalline Powder Neoplastic Drug Chemosterilant For Insects (Epa 1998)Masse moléculaire :130.08Peramivir Trihydrate
CAS :Peramivir Trihydrate (RWJ-270201) is a neuraminidase inhibitor (IC50: 0.09 nM) which prevents normal processing of virus particles such that virus particles areFormule :C15H28N4O4·3H2ODegré de pureté :99.52% - ≥95%Couleur et forme :SolidMasse moléculaire :382.45Ref: TM-T2522
2mg47,00€5mg70,00€10mg103,00€25mg188,00€50mg311,00€100mg439,00€200mg635,00€500mg938,00€Folic Acid EP Impurity H Trisodium Salt
CAS :Formule :C31H28N9O10·3NaMasse moléculaire :686.62 3*22.99Ribavirin Impurity 33
CAS :Formule :C15H19N3O9Couleur et forme :Pale Yellow LiquidMasse moléculaire :385.33Decarboxylated (S)-Adenosyl Methionine Tritrifluoromethanesulfonic Acid
CAS :Formule :C14H23N6O3S·CF3O3S·2CHF3O3SMasse moléculaire :355.44 149.06 2*150.07Emtricitabine 6’-Disulfide
CAS :Produit contrôléApplications An impurity of Emtricitabine synthesis.Formule :C16H18F2N6O4S4Couleur et forme :NeatMasse moléculaire :524.6093’-Amino-3’-deoxythymidine
CAS :Produit contrôléImpurity Zidovudine Impurity; Stability Hygroscopic, Moisture Sensitive Applications A metabolite of Zidovudine (3'-Azido-3'-deoxythymidine; AZT). References Qian, M., et al.: Biochem. Pharmacol., 48, 383 (1994), Diwan, B., et al.: Toxicol. Appl. Pharmacol., 161, 82 (1999) , Lim, S., et al.: J. Biol. Chem., 276, 23616 (2001), Von Tungeln, L., et al.: Carcinogenesis, 23, 1427 (2002),Formule :C10H15N3O4Couleur et forme :White To Off-WhiteMasse moléculaire :241.24Ribavirin Impurity 39
CAS :Formule :C18H21N5O9Couleur et forme :White To Off-White SolidMasse moléculaire :451.39Lamivudine EP Impurity I (Troxacitabine)
CAS :Formule :C8H11N3O4Couleur et forme :White To Off-White SolidMasse moléculaire :213.199-[4-Acetoxy-3-(acetoxymethyl)butyl]-2-amino-6-chloropurine
CAS :Produit contrôléFormule :C14H18ClN5O4Couleur et forme :NeatMasse moléculaire :355.78Dapagliflozin Impurity 55
CAS :Formule :C7H3BrCl2OCouleur et forme :White To Off-White SolidMasse moléculaire :253.90Adefovir Dipivoxyl Impurity C
CAS :Formule :C16H26N5O6PCouleur et forme :Off-White SolidMasse moléculaire :415.39Dapagliflozin hydroxy Impurity (Mixture of Diastereomers)
CAS :Applications (1S)-1,5-anhydro-1-C-[4-Chloro-3-[(4-ethoxyphenyl)hydroxymethyl]phenyl]-D-glucitol is an impurity of the drug Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor. References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)Formule :C21H25ClO7Couleur et forme :White To Off-WhiteMasse moléculaire :424.872Acyclovir EP Impurity Q
Acyclovir EP Impurity Q is a drug product that is used as the impurity standard for Acyclovir EP. It is a natural metabolite of acyclovir and may be found in the urine of patients taking this drug. Acyclovir EP Impurity Q has shown to have antiviral activity against herpes simplex virus type 1 and type 2. The structure of this compound has been determined by nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry.Degré de pureté :Min. 95%
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