Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
Produits appartenant à la catégorie "Nucléosides et Nucléotides"
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Dapagliflozin Impurity 26
CAS :Dapagliflozin Impurity 26 is an impurity that is found in the chemical analysis of Dapagliflozin. It is a metabolite, which is not present in the drug product and does not have any biological activity. Dapagliflozin Impurity 26 has been shown to be a high purity, analytical standard for HPLC and can be used as an API impurity for drug development. This compound can also be synthesized by natural or synthetic means.Degré de pureté :Min. 95%Deoxycytidine triphosphate trisodium salt
CAS :Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.Formule :C9H13N3Na3O13P3Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :533.11-N-Methyl-5-Fluorouracil
CAS :Formule :C5H5FN2O2Couleur et forme :White To Off-White SolidMasse moléculaire :144.11Fludarabine Phosphate
CAS :Formule :C10H13FN5O7PCouleur et forme :White To Off-White SolidMasse moléculaire :365.22Dapagliflozin Impurity 2
CAS :Dapagliflozin impurity 2 is an impurity of dapagliflozin. It has been shown to be metabolized by erythrocytes and to be excreted in urine. Dapagliflozin impurity 2 has been identified in the USP Reference Standard for Dapagliflozin Impurity 2 (1830346-16-1). This material is available for custom synthesis, research, and development.Formule :C15H14BrClODegré de pureté :Min. 95%Masse moléculaire :325.63 g/molDapagliflozin Impurity 24 (Mixture of Diastereomers)
CAS :Formule :C21H25ClO7Couleur et forme :White To Off-White SolidMasse moléculaire :424.87Folic Acid Impurity 3 (6-(Hydroxymethyl)Pterin)
CAS :Formule :C7H7N5O2Couleur et forme :Yellow SolidMasse moléculaire :193.17Adenosine-3'-monophosphate
CAS :Produit contrôléApplications Adenosine-3'-monophosphate (cas# 84-21-9) is a useful research chemical.Formule :C10H14N5O7PCouleur et forme :NeatMasse moléculaire :347.2212alfa-(Z)-Brivudine
CAS :Formule :C11H13BrN2O5Couleur et forme :Pale Yellow SolidMasse moléculaire :333.14Remdesivir related compound 9
CAS :Remdesivir related compound 9 is a drug product that is an analytical standard. It is a natural API impurity, which has been synthesized for use as an impurity standard. This compound has been custom synthesized to be used as a research and development chemical. CAS No. 1439900-56-7 is the number of this synthetic drug product. It can be used in HPLC standards and it meets pharmacopoeia requirements for purity. The niche market for this compound is high purity analytical standards, including HPLC standards.Formule :C21H27N2O7PDegré de pureté :Min. 95%Masse moléculaire :450.42 g/molAdefovir Dipivoxyl Impurity A
CAS :Formule :C14H22N5O6PCouleur et forme :White To Off-White SolidMasse moléculaire :387.33Sofosbuvir Impurity 41
CAS :Formule :C16H25FN3O9PCouleur et forme :White To Off-White SolidMasse moléculaire :453.36Adenosine 5'-Monophosphate
CAS :Produit contrôléApplications Adenosine 5'-Monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists. References Hong, J.A. et al.: J. Med. Chem., 52, 5485 (2009); Korboukh I. et al.: J. Med. Chem., 55, 6467 (2012)Formule :C10H14N5O7PCouleur et forme :NeatMasse moléculaire :347.22HBT1
CAS :HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neuronsFormule :C16H17F3N4O2SDegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :386.39Nelarabine Impurity 11
CAS :Formule :C6H7N5OCouleur et forme :Off-White SolidMasse moléculaire :165.16Decitabine Impurity 17
CAS :Formule :C10H14N4O5Couleur et forme :White To Off-White SolidMasse moléculaire :270.25Emtricitabine Impurity 15
CAS :Formule :C17H22FN8O6PSCouleur et forme :White To Off-White SolidMasse moléculaire :516.45Cytosine-13C-15N2
CAS :Formule :C313CH5N15N2OCouleur et forme :Off-White SolidMasse moléculaire :114.085-Methoxypyrimidine-2,4(1H,3H)-dione (5-Methoxyuracil)
CAS :Produit contrôléFormule :C5H6N2O3Couleur et forme :NeatMasse moléculaire :142.11Favipiravir Impurity 3
CAS :Formule :C5H4ClN3O2Couleur et forme :White To Off-White SolidMasse moléculaire :173.56Remdesivir impurity 5
CAS :Remdesivir impurity 5 is a metabolite that is generated in the body following metabolism and excretion of remdesivir. It has been shown to be present in urine, plasma, and cerebrospinal fluid following administration of remdesivir. Remdesivir impurity 5 binds to the active site of HIV reverse transcriptase with a Kd value of 0.5 nM. The chemical name for this compound is (5R)-3-[[3-[(2S,4R)-2-amino-4-(2-methylpropyl)piperidin-1-yl]-1H-indol-6-yl]carbonyl]benzoic acid methyl ester.Formule :C21H27N2O7PDegré de pureté :Min. 95%Masse moléculaire :450.42 g/molAcyclovir
CAS :Acyclovir (Aciclovir) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2,Formule :C8H11N5O3Degré de pureté :100% - 100.00%Couleur et forme :Crystals From Methanol SolidMasse moléculaire :225.2Cabotegravir
CAS :Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (Formule :C19H17F2N3O5Degré de pureté :98.55% - 99.92%Couleur et forme :SolidMasse moléculaire :405.35Abacavir Carboxylate Trifluoroacetate
CAS :Formule :C14H16N6O2·C2HF3O2Masse moléculaire :300.32 114.02Emtricitabine Isopropyl Carbamate
Formule :C12H16FN3O5SCouleur et forme :White To Off-White SolidMasse moléculaire :333.34Canagliflozin Impurity 10
CAS :Formule :C24H25FO6SCouleur et forme :White To Off-White SolidMasse moléculaire :460.52Decitabine Impurity 6 (β-D-Erythro-Pentopyranoside-Methyl-2-Deoxy-bis(4-methylbenzoate))
CAS :Formule :C22H24O6Couleur et forme :Pale Yellow LiquidMasse moléculaire :384.43Adenosine 5’-Diphosphate-13C5 Ammonium Salt Hydrate
CAS :Produit contrôléStability Moisture Sensitive Applications Adenosine 5’-Diphosphate-13C5 Ammonium Salt Hydrate is the isotope labelled analog of Adenosine 5’-Diphosphate Ammonium Salt Hydrate (A281700); a nucleoside diphosphate that interacts with a family of ADP receptors found on platelets (P2Y1, P2Y12 and P2X1), to induce platelet activation. ADP in the blood is converted to adenosine by the action of ecto-ADPases, inhibiting further platelet activation via adenosine receptors. References Gamba, G. et al.: Haematologia, 58, 1215 (1973); Dejana, E. et al.: Thromb. Haemost., 39, 135 (1978)Formule :C513C5H15N5O10P2xNH3xH2OCouleur et forme :NeatMasse moléculaire :432.16Cytidine-5'-Diphosphate Disodium Salt
CAS :Formule :C9H13N3O11P2·2NaCouleur et forme :White To Off-White SolidMasse moléculaire :401.16 2*22.99Favipiravir Impurity 25
Formule :C7H9N3O3Couleur et forme :White To Off-White SolidMasse moléculaire :183.172-Acetamido-7-[[2-(acetyloxy)ethoxy]methyl]-6,7-dihydro-1H-purin-6-one
CAS :2-Acetamido-7-[[2-(acetyloxy)ethoxy]methyl]-6,7-dihydro-1H-purin-6-one is a drug development impurity that is manufactured by the pharmaceutical company. This impurity has been shown to be a metabolite of the drug.Formule :C12H15N5O5Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :309.28 g/molRifamycin S
CAS :Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteriaFormule :C37H45NO12Degré de pureté :98.74%Couleur et forme :Yellow Orange Crystalline PowderMasse moléculaire :695.75Nelarabine
CAS :Formule :C11H15N5O5Couleur et forme :White To Off-White SolidMasse moléculaire :297.27Adefovir Dipivoxyl Impurity I (Adefovir Dipivoxyl N6-Hydroxymethyl Impurity)
CAS :Formule :C21H34N5O9PCouleur et forme :White To Off-White SolidMasse moléculaire :531.511-[2,3-O-Isopropylidene-b-D-ribofuranosyl]-1,2,4-triazole-3-carboxylic acid methyl ester
CAS :1-[2,3-O-Isopropylidene-b-D-ribofuranosyl]-1,2,4-triazole-3-carboxylic acid methyl ester is a synthetic compound that has been shown to inhibit the growth of Mycobacterium tuberculosis in culture. The metabolite is used as an impurity standard for HPLC analysis of this active compound. It has not yet been approved for use as a drug product.Formule :C12H17N3O6Degré de pureté :Min. 95%Masse moléculaire :299.28 g/molUridine (Adenosine EP Impurity F, Cytarabine EP Impurity B)
CAS :Formule :C9H12N2O6Couleur et forme :White To Off-White SolidMasse moléculaire :244.20Folic Acid (Folinic Acid EP Impurity C)
CAS :Formule :C19H19N7O6Couleur et forme :Yellow SolidMasse moléculaire :441.40Valacyclovir Impurity 2
CAS :Formule :C7H12O5Couleur et forme :Colourless LiquidMasse moléculaire :176.17Peramivir Impurity 6
CAS :Formule :C15H28N2O4Couleur et forme :White To Off-White SolidMasse moléculaire :300.40Valacyclovir Related Compound D
CAS :Valacyclovir Related Compound D is a synthetic metabolite of Valacyclovir. It is the primary metabolite of Valacyclovir, which has been shown to inhibit the activity of bacterial DNA polymerase. Valacyclovir Related Compound D is an impurity standard for valacyclovir and can be synthesized in quantities as per customer requirement.Formule :C15H24N6O4Degré de pureté :Min. 95%Masse moléculaire :352.39 g/molRibavirin EP Impurity D (Ribavirin USP Related Compound D)
CAS :Formule :C3H4N4OCouleur et forme :White To Off-White SolidMasse moléculaire :112.09Triclosan
CAS :Triclosan (Irgasan) is an antibacterial and antifungal agent.Formule :C12H7Cl3O2Degré de pureté :99.63%Couleur et forme :White Solid CrystallineMasse moléculaire :289.54Melphalan EP Impurity A DiHCl (Dihydroxy Melphalan DiHCl)
CAS :Formule :C13H20N2O4·2HClCouleur et forme :Pale Yellow To Off-White SolidMasse moléculaire :268.31 2*36.46Lamivudine EP Impurity G
CAS :Formule :C8H11N3O4SCouleur et forme :White To Off-White SolidMasse moléculaire :245.25(2R,5S)-Emtricitabine Carboxylic Acid
CAS :Formule :C8H8FN3O4SCouleur et forme :White To Off-White SolidMasse moléculaire :261.235-(2-deoxy-2-fluoro-β-D-ribofuranosyl)-2,4(1H,3H)-Pyrimidinedione
Formule :C9H11FN2O5Masse moléculaire :246.19Aciclovir (Acyclovir) EP Impurity G (Acyclovir USP Related Compound G)
CAS :Formule :C12H15N5O5Couleur et forme :Off-White SolidMasse moléculaire :309.28Entecavir
CAS :Formule :C12H15N5O3Couleur et forme :White To Off-White SolidMasse moléculaire :277.28Sofosbuvir Impurity 34 (GS-606965)
CAS :Formule :C10H14FN2O8PCouleur et forme :White To Off-White SolidMasse moléculaire :340.20Uridine Diphosphate Choline (UDPC) Sodium Salt
CAS :Formule :C14H24N3O12P2·NaCouleur et forme :White To Off-White SolidMasse moléculaire :488.31 22.99Capecitabine Impurity 5
Formule :C21H32FN3O8Couleur et forme :Colourless LiquidMasse moléculaire :473.50Emtricitabine Impurity 24
CAS :Formule :C20H29FN2O6S2Couleur et forme :White To Off-White SolidMasse moléculaire :476.58Stavudine Triphosphate Triethylammonium Salt
CAS :Produit contrôléStability Hygroscopic Applications Stavudine Triphosphate Trisodium Salt has a free acid of Stavudine Triphosphate. Stavudine Triphosphate inhibits HIV-1 RT (reverse transcriptase). Stavudine Triphosphate Trisodium Salt is a metabolite of Stavudine. References Vaccaro, J.A., Parnell K.M., Terezakis S.A., Anderson, K.S.: Antimicrob. Agents Ch., 44, 217 (2000)Formule :C10H15N2O13P3•x(EtN)Couleur et forme :NeatMasse moléculaire :464.15(R,S)-Adenosyl-L-Methionine Tri-1,4-Butanedisulfonate
CAS :Formule :C15H22N6O5S·C4H9O6S2·2C4H10O6S2Masse moléculaire :399.45 217.24 2*218.25Capecitabine Impurity 23
Formule :C20H26FN3O10Couleur et forme :White To Off-White SolidMasse moléculaire :487.442-Amino-7-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-1,7-dihydro-6H-purin-6-one (N-7 Isomer of Ganciclovir)
CAS :Couleur et forme :NeatDapagliflozin Impurity 17
CAS :Dapagliflozin Impurity 17 is a research and development impurity standard for HPLC. It is a natural product and is registered under CAS No. 1807632-93-4. Dapagliflozin Impurity 17 is a metabolite of dapagliflozin, an oral anti-diabetic drug that has been shown to be effective in the treatment of type 2 diabetes. This impurity standard has been synthesized as a research tool for the study of metabolism and pharmacokinetics, as well as analytical methods validation.Formule :C15H14Br2ODegré de pureté :Min. 95%Masse moléculaire :370.08 g/molClofarabine-13C-15N3
CAS :Formule :C913CH11ClFN215N3O3Couleur et forme :White To Off-White SolidMasse moléculaire :307.65Folic Acid Impurity: 6-(chloromethyl)pteridine-2,4-Diamine HCl
CAS :Formule :C7H7ClN6·HClCouleur et forme :Yellow SolidMasse moléculaire :210.63 36.464-Amino-1-[(2S,5R)-2-(hydroxy-methyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
CAS :Couleur et forme :NeatCangrelor Tetrasodium Salt
CAS :Formule :C17H21Cl2F3N5O12P3S2·4NaCouleur et forme :White To Off-White SolidMasse moléculaire :772.32 4*22.99Folinic Acid EP Impurity B (Mixture of Diastereomers)
CAS :Formule :C21H23N7O8Couleur et forme :Yellow SolidMasse moléculaire :501.46Adenosine-1'-13C
CAS :Produit contrôléFormule :CC9H13N5O4Couleur et forme :White To Off-WhiteMasse moléculaire :268.234Valaciclovir EP Impurity E Enantiomer (Valacyclovir USP Related Compound E Enantiomer)
CAS :Formule :C21H26N6O6Masse moléculaire :458.489-(2,3-Dideoxy-β-D-glycero-pentofuranosyl)-9H-purin-6-amine (2',3'-Dideoxyadenosine)
CAS :Produit contrôléFormule :C10H13N5O2Couleur et forme :NeatMasse moléculaire :235.243Entecavir EP Impurity C (8-Hydroxy Entecavir)
CAS :Formule :C12H15N5O4Couleur et forme :White To Off-White SolidMasse moléculaire :293.28Adenosine-5'-Diphosphate Disodium Salt
CAS :Formule :C10H13N5O10P2·2NaMasse moléculaire :425.19 2 22.99Ribavirin Impurity 56-13C-15N4 (Aminoguanidine-13C-15N4)
CAS :Formule :CH615N4·5H2SO4Masse moléculaire :79.05 0.5*98.07Abacavir EP Impurity B
CAS :Formule :C18H21ClN10OCouleur et forme :Pale Pink SolidMasse moléculaire :428.89Remdesivir impurity 9
CAS :CAS No.: 159970-52-6 Remdesivir impurity 9 is a synthetic, natural and drug development impurity standard. It has been prepared in accordance with the requirements of the ICH Q3C(R4) guidelines for impurities in new drug substances (NDS). Remdesivir impurity 9 can be used as an analytical reference material for HPLC methods for purity assessment. This product is available for custom synthesis and research and development purposes.Formule :C27H35N6O8PDegré de pureté :Min. 95%Masse moléculaire :602.58 g/molCangrelor Impurity 3
CAS :Formule :C16H22F3N5O4S2Couleur et forme :Off-White SolidMasse moléculaire :469.504’-epi-Entecavir
CAS :Produit contrôléImpurity Entecavir EP Impurity D Applications 4’-epi-Entecavir is an epimeric impurity of the antiviral drug Entecavir (E558900).Formule :C12H15N5O3Couleur et forme :WhiteMasse moléculaire :277.28Azacitidine Impurity 47 (Mixture of Diastereomers)
CAS :Formule :C27H24O8Couleur et forme :Colorless Sticky OilMasse moléculaire :476.48Decitabine Impurity 6 (α-D-Erythro-Pentopyranoside-Methyl-2-Deoxy-bis(4-methylbenzoate))
CAS :Formule :C22H24O6Couleur et forme :Colorless LiquidMasse moléculaire :384.43Remdesivir impurity 14
Remdesivir impurity 14 is a research and development product that belongs to the class of drugs. It is a synthetic metabolite with high purity. Remdesivir impurity 14 meets the pharmacopoeia standard for drug products and drug development. It has been synthesized to be used as an analytical standard for HPLC analysis of remdesivir. This product also has niche applications in metabolism studies, because it is a natural metabolite with its own metabolic pathway.Formule :C18H18N5O7PDegré de pureté :Min. 95%Masse moléculaire :447.34 g/molDecitabine Impurity 36
CAS :Formule :C22H18Cl2N4O6Couleur et forme :White To Off-White SolidMasse moléculaire :505.31Guanine
CAS :Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, nesoiFormule :C5H5N5OCouleur et forme :White Yellow PowderMasse moléculaire :151.13
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