Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
Produits appartenant à la catégorie "Nucléosides et Nucléotides"
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(2R,5R)-Emtricitabine Carboxylic Acid
Formule :C8H8FN3O4SCouleur et forme :Off-White SolidMasse moléculaire :261.23rac-Melphalan EP Impurity E HCl
Formule :C15H23ClN2O3·HClCouleur et forme :White To Off-White SolidMasse moléculaire :314.82 36.46Ammeline
CAS :Applications Ammeline is a metabolite of Melamine (1) (M208700), which acts as a non-protein nitrogen food additive (2). Also present in pet foods as well (3).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants. References 1. Mast RW. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Ehling S. et al.: Food Addit Contam. 2007 Dec;24(12):1319-25.3. Vail T. et al.: J Anal Toxicol. 2007 Jul-Aug;31(6):304-12.Formule :C3H5N5OCouleur et forme :ColourlessMasse moléculaire :127.10(1S,3S,4R)-Entecavir
CAS :Formule :C12H15N5O3Couleur et forme :Off-White SolidMasse moléculaire :277.28Famciclovir impurity 5
CAS :Formule :C11H15N5O3Couleur et forme :Off-White SolidMasse moléculaire :265.27(R)-Canagliflozin Furanose Impurity
Formule :C24H25FO5SCouleur et forme :Off-White SolidMasse moléculaire :444.53Aciclovir (Acyclovir) EP Impurity F (Acyclovir USP Related Compound F)
CAS :Formule :C10H13N5O4Couleur et forme :Off-White SolidMasse moléculaire :267.25Cytidine-5'-triphosphate
CAS :Cytidine-5'-triphosphate (Cytidine triphosphate) acts as an energy source and activates protein kinase reactions.Formule :C9H16N3O14P3Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :483.16Dapagliflozin Impurity 14
Formule :C21H25ClO6Couleur et forme :White To Off-White SolidMasse moléculaire :408.88AMPA receptor modulator-2
CAS :AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.Formule :C15H6F6N4OSDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :404.29Ref: TM-T37734
1mg123,00€5mg298,00€10mg393,00€25mg628,00€50mg905,00€100mg1.254,00€1mL*10mM (DMSO)328,00€rac-Melphalan N-Oxide Impurity HCl
Formule :C13H18Cl2N2O3·HClCouleur et forme :Off-White SolidMasse moléculaire :321.21 36.46Famciclovir Impurity 2
CAS :Formule :C9H13N5O2Couleur et forme :White To Off-White SolidMasse moléculaire :223.24Sofosbuvir Impurity 36
Formule :C10H15FN2O11P2Couleur et forme :White To Off-White SolidMasse moléculaire :420.18Melphalan EP Impurity D DiHCl (Monohydroxy Melphalan DiHCl)
CAS :Formule :C13H19ClN2O3·2HClCouleur et forme :Pale Yellow SolidMasse moléculaire :286.76 2*36.46Peramivir Impurity 53
Formule :C28H52N8O6Couleur et forme :White To Off-White SolidMasse moléculaire :596.77Inosine Impurity 2
CAS :Formule :C12H12N4O4Couleur et forme :White To Off-White SolidMasse moléculaire :276.25GS 441524 triphosphate
CAS :Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.Formule :C12H12N5O13P3·4NaDegré de pureté :(31P-Nmr) Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :531.20 g/molOxiracetam Related Compound 3
CAS :Formule :C6H8N2O2Couleur et forme :Off-White SolidMasse moléculaire :140.14Cytidine 5'-diphosphate trisodium salt
CAS :CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.Formule :C9H15N3Na3O11P2Degré de pureté :99.64%Couleur et forme :White Crystalline PowderMasse moléculaire :472.15Folinic Acid Impurity 8
CAS :Formule :C15H18N6O3Couleur et forme :Pale Yellow SolidMasse moléculaire :330.35Adenosine-5'-Monophosphate Sodium Salt
CAS :Formule :C10H13N5O7P·NaCouleur et forme :White To Off-White SolidMasse moléculaire :346.22 22.99Capecitabine 2',3'-cyclic carbonate
CAS :Capecitabine is a prodrug that is converted to 5-fluorouracil in the body. It has been used for many years in the treatment of breast cancer and colorectal cancer. Capecitabine 2',3'-cyclic carbonate is an analytical standard, research and development tool, high purity drug product, and impurity standard for HPLC analysis. This compound is also used as a pharmacopoeia reference material for quality control testing. Capecitabine 2',3'-cyclic carbonate can be custom synthesized or purified from natural or synthetic sources.Formule :C16H20FN3O7Degré de pureté :Min. 95%Masse moléculaire :385.34 g/molPteroic Acid (>85%)
CAS :Produit contrôléImpurity Methotrexate EP Impurity D N-Desmethyl Impurity Applications Pteroic Acid (Methotrexate EP Impurity D N-Desmethyl Impurity) is a constituent as well as a degradation product of Folic Acid (F680300) formed via enzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutamate synthetase. References Vickers, P.J. et al.: Can. J. Biochem. Cell Biol., 63, 777 (1985): Tafolla, W.H. et al.: J. Pharmac. Sci., 70, 1273 (1981); Iwai, K. et al.: J. Butrit. Sci. Vitaminol., 23, 95 (1977);Formule :C14H12N6O3Degré de pureté :>85%Couleur et forme :NeatMasse moléculaire :312.28Acyclovir Benzoate
CAS :Formule :C15H15N5O4Couleur et forme :White To Off-White SolidMasse moléculaire :329.321-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid methyl ester
CAS :Intermediate in the synthesis of ribavirinFormule :C9H13N3O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :259.22 g/molRemdesivir Impurity 10
Formule :C27H35N6O8PCouleur et forme :Pale Orange SolidMasse moléculaire :602.58(R)-AMPA
CAS :inactive enantiomer of AMPAFormule :C7H10N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :186.17Capecitabine Impurity 16
Formule :C20H30FN3O9Couleur et forme :White To Off-White SolidMasse moléculaire :475.47Emtricitabine
CAS :Formule :C8H10FN3O3SCouleur et forme :White To Off-White SolidMasse moléculaire :247.24Oxiracetam-13C2-15N
CAS :Formule :C413C2H10N15NO3Couleur et forme :White To Off-White SolidMasse moléculaire :161.13Vitamin B12
CAS :Cyanocobalamin, a B-complex vitamin from gut microbes, is essential for blood, DNA, and metabolism; its lack causes anemia and nerve damage.Formule :C63H88CoN14O14PDegré de pureté :98% - 99.54%Couleur et forme :SolidMasse moléculaire :1355.37Cangrelor Impurity 2
CAS :Formule :C16H23F3N5O7PS2Couleur et forme :Off-White To Grey SolidMasse moléculaire :549.48Adenosine 5'-Triphosphate-13C5 Disodium Salt
CAS :Formule :C513C5H14N5O13P3·2NaMasse moléculaire :510.11 2 22.99Emtricitabine Enantiomer
CAS :Formule :C8H10FN3O3SCouleur et forme :White To Off-White SolidMasse moléculaire :247.24Didanosine
CAS :Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).Formule :C10H12N4O3Degré de pureté :99.64%Couleur et forme :White Crystalline PowderMasse moléculaire :236.23Azacitidine Impurity 37
CAS :Formule :C8H12N4O5Couleur et forme :White To Off-White SolidMasse moléculaire :244.21Adenosine Monophosphate (mixture of 2'(3')-phosphate isomers)-13C5 Sodium Salt
CAS :Produit contrôléApplications Labelled AMP mixture References Jackson, E.K. et al.: Hypertension, 56, 151 (2010); Jackson, E.K. et al: J. Bio. Chem., 284, 33097 (2009);Formule :C513C5H14N5O7P•x(Na)Couleur et forme :NeatMasse moléculaire :352.182299Decitabine Impurity 44
CAS :Formule :C16H18N4O5Couleur et forme :White To Off-White SolidMasse moléculaire :346.34Penciclovir
CAS :Formule :C10H15N5O3Couleur et forme :White To Off-White SolidMasse moléculaire :253.26Methyl 2-deoxy-D-ribopyranoside
CAS :Methyl 2-deoxy-D-ribopyranoside (2DDR) is a natural compound that can be found as an impurity in some pharmaceuticals. The chemical structure of 2DDR is similar to 6-fluoro-3-indoxyl beta-D-galactopyranoside, which is used to treat tuberculosis. The metabolism of 2DDR has been studied, and it has been found that this metabolite is excreted in the urine unchanged or conjugated with glucuronic acid. This product can be used for drug development and research and development. It can also be used as an impurity standard for HPLC analysis or as a custom synthesis for niche applications.Formule :C6H12O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :148.16 g/molGemcitabine Impurity 3 (Mixture of Diastereomers)
Formule :C9H11F2N2O6Couleur et forme :White To Off-White SolidMasse moléculaire :282.20Entecavir
CAS :Applications An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process. References Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997), Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (2003), Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (2006),Formule :C12H15N5O3Couleur et forme :NeatMasse moléculaire :277.28Cabotegravir-d5
CAS :Formule :C19H12D5F2N3O5Couleur et forme :White To Off-White SolidMasse moléculaire :410.39Dapagliflozin Impurity 30
CAS :Dapagliflozin Impurity 30 is a natural impurity found in the drug Dapagliflozin. It is an analytical standard used for HPLC quantification of dapagliflozin, and it can be used as a pharmacopoeia reference material or research and development material. Dapagliflozin Impurity 30 is synthesized by using a custom synthesis protocol. The CAS number for this compound is 1373321-04-0.Formule :C21H25ClO6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :408.9 g/molUridine Monophosphate Disodium Salt (Mixture of 2’-Isomer and 3’-Isomer)
Formule :C9H11N2O9P·2NaMasse moléculaire :322.17 2*22.99Remdesivir Impurity 9
CAS :Formule :C27H35N6O8PCouleur et forme :White To Off-White SolidMasse moléculaire :602.58Oxiracetam Related Compound 9
Formule :C5H10ClNO2Couleur et forme :Colorless LiquidMasse moléculaire :151.59Peramivir
CAS :Peramivir is a neuraminidase inhibitor used to treat influenza by preventing virus release from cells.Formule :C15H28N4O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :328.41Folinic Acid EP Impurity F Disodium Salt
CAS :Formule :C20H19N7O7·2NaMasse moléculaire :469.42 2*22.99Canagliflozin Monoacetyl Impurity
CAS :Formule :C26H27FO6SCouleur et forme :White To Off-White SolidMasse moléculaire :486.56Remdesivir Impurity 34-13C-d3-15N2 (GS-441524-13C-d3-15N2)
CAS :Formule :C1113CH10D3N315N2O4Masse moléculaire :297.26Gemcitabine-13C-15N2
CAS :Formule :C813CH11F2N15N2O4Couleur et forme :White To Off-White SolidMasse moléculaire :266.18Canagliflozin hemihydrate
CAS :Canagliflozin hemihydrate (TA 7284) treats type 2 diabetes by blocking SGLT2, leading to glucose excretion in urine.Formule :C48H52F2O11S2Degré de pureté :99.42% - 99.96%Couleur et forme :SolidMasse moléculaire :907.05Valaciclovir EP Impurity J
CAS :Formule :C14H22N6O4Couleur et forme :White To Off-White SolidMasse moléculaire :338.37Abacavir Impurity 2
CAS :Formule :C10H14ClN5OCouleur et forme :White To Off-White SolidMasse moléculaire :255.71Emtricitabine Thioacetate
Formule :C10H12FN3O3S2Couleur et forme :Pale Yellow SolidMasse moléculaire :305.34S29434
CAS :S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).Formule :C21H18N4O3Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :374.39Sofosbuvir Impurity 43 Cyclohexylamine Salt
CAS :Formule :C12H18NO5P·C6H13NCouleur et forme :White To Off-White SolidMasse moléculaire :287.25 99.18Dilazep dihydrochloride
CAS :Dilazep dihydrochloride inhibits adenosine uptake, ischemia, nucleoside transport, platelet aggregation, and acts as a vasodilator.Formule :C31H46Cl2N2O10Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :677.61Ref: TM-T15130
5mg47,00€10mg70,00€25mg126,00€50mg202,00€100mg329,00€200mg474,00€1mL*10mM (DMSO)65,00€3'-Deoxy-3'-chlorothymidine
CAS :Please enquire for more information about 3'-Deoxy-3'-chlorothymidine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C10H13ClN2O4Degré de pureté :Min. 95%Masse moléculaire :260.67 g/molRibavirin Impurity 19 (Mixture of α- and β- Isomers)
CAS :Formule :C13H18O9Couleur et forme :White To Off-White SolidMasse moléculaire :318.28Remdesivir
CAS :Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase ofFormule :C27H35N6O8PDegré de pureté :100% - 99.98%Couleur et forme :SolidMasse moléculaire :602.58Ref: TM-T7766
1mg119,00€5mg323,00€10mg510,00€25mg757,00€50mg938,00€100mg1.434,00€200mg1.882,00€1mL*10mM (DMSO)427,00€Famciclovir N7-Isomer
CAS :Formule :C14H19N5O4Couleur et forme :White To Off-White SolidMasse moléculaire :321.34PSI 7976
CAS :PSI 7976 is an analog of the nucleophilic attack drug, ribavirin. PSI 7976 inhibits the hepatitis C virus (HCV) replicon by inhibiting the function of the NS5B polymerase. In clinical studies, PSI 7976 has been shown to be active against HCV genotype 1 and 3. It has also been shown to inhibit replication of HIV-1 in vitro and to act synergistically with lamivudine against HIV-1 in human cells. PSI 7976 may be useful as a potential antiviral agent for treatment of other viral infections such as hepatitis B virus (HBV), herpes simplex virus type 2 (HSV-2), or cytomegalovirus (CMV).Formule :C22H29FN3O9PDegré de pureté :Min. 95%Masse moléculaire :529.45 g/molCabotegravir Glucuronide Triethylamine Salt
CAS :Formule :C25H25F2N3O11·Et3NMasse moléculaire :581.49Cytarabine triphosphate
CAS :Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.Formule :C9H16N3O14P3Couleur et forme :SolidMasse moléculaire :483.16Entecavir
CAS :Entecavir (SQ34676), a guanosine analogue, treats chronic HBV; may cause hepatitis B flares, not clear liver injury.Formule :C12H15N5O3Degré de pureté :100% - 99.14%Couleur et forme :White To Off-White/Yellow Crystalline PowderMasse moléculaire :277.28Ref: TM-T0085L
5mg50,00€10mg87,00€25mg116,00€50mg166,00€100mg283,00€200mg432,00€500mg697,00€1mL*10mM (DMSO)50,00€Remdesivir impurity 13
CAS :Remdesivir impurity 13 is a metabolite of remdesivir, which is a drug product that is custom synthesized by us. This compound has been shown to be natural and can be found in the human body. Remdesivir impurity 13 has been studied extensively for its metabolic pathway and as a potential impurity standard for HPLC analysis.Formule :C27H35N6O8PDegré de pureté :Min. 95%Masse moléculaire :602.58 g/mol
