Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
Produits appartenant à la catégorie "Nucléosides et Nucléotides"
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Cladribine EP Impurity C
CAS :Produit contrôléFormule :C5H4ClN5Couleur et forme :NeatMasse moléculaire :169.57Peramivir
CAS :Formule :C15H28N4O4Couleur et forme :White To Off-White SolidMasse moléculaire :328.41ent-Entecavir
CAS :Formule :C12H15N5O3Couleur et forme :White To Off-White SolidMasse moléculaire :277.28Fosamprenavir Calcium
CAS :Formule :C25H34N3O9PS·CaCouleur et forme :White To Off-White SolidMasse moléculaire :583.59 40.08Acyclovir acetate
CAS :Acyclovir is an antiviral agent that prevents the growth of herpes simplex virus. Acyclovir is a prodrug, which is converted to acycloguanosine 5'-triphosphate (ACV-TP) in vivo. ACV-TP inhibits viral DNA polymerase and thereby prevents viral genome replication, replication. The molecular structure of Acyclovir was determined by X-ray crystallography at 3.2 Å resolution. It has been shown that ACV-TP can be activated by chloride ions and it has been suggested that this activation may be the result of an interaction with a ligand. ACV-TP binds to guanine residues in the DNA chain and prevents the formation of hydrogen bonds between guanine and adenine or cytosine residues in the same chain, preventing DNA replication.Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :267.24 g/molCidofovir-13C-15N2 Disodium Salt
CAS :Formule :C713CH12N15N2O6P·2NaCouleur et forme :White To Off-White SolidMasse moléculaire :280.15 2*22.99Aciclovir EP impurity J
CAS :Aciclovir EP impurity J is a drug product that is used as an analytical standard in HPLC. Aciclovir EP impurity J is the natural metabolite of aciclovir, which is an antiviral drug. It is not active against herpesviruses but has been shown to inhibit the growth of human cells infected with cytomegalovirus. Aciclovir EP impurity J has been studied for its effects on drug metabolism and pharmacokinetics. Aciclovir EP impurity J has been shown to be excreted primarily in urine, with some excretion in the feces.Formule :C14H16N10O4Degré de pureté :Min. 95%Masse moléculaire :388.34 g/molCidofovir Disodium Salt
CAS :Formule :C8H12N3O6P·2NaCouleur et forme :White To Off-White SolidMasse moléculaire :277.17 2*22.99Bictegravir Metabolite M15 Triethylamine Salt
CAS :Formule :C27H26F3N3O11·Et3NMasse moléculaire :625.51 101.19Dibenzyl Entecavir (3',5'-Di-O-Benzyl Entecavir)
CAS :Formule :C26H27N5O3Couleur et forme :White To Off-White SolidMasse moléculaire :457.53S07-2010
CAS :S07-2010 is a pan-Aldo-Keto Reductase 1C3 (AKR1C3) inhibitor with potential anti-cancer activity, inducing apoptosis in A549/DDP cells.Formule :C19H21N3O3SCouleur et forme :SolidMasse moléculaire :371.45AKR1C3-IN-1
CAS :AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).Formule :C16H15NO4SDegré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :317.36Cytidine 5’-Diphosphate Ethanolamine Disodium Salt
CAS :Formule :C11H20N4O11P2·2NaMasse moléculaire :446.25 2*22.99Adenosine-2’,3’-cyclic Monophosphate Sodium Salt
CAS :Produit contrôléFormule :C10H11N5O6P·NaCouleur et forme :NeatMasse moléculaire :351.1882,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
CAS :2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone is a synthetic building block which can undergo reaction with nucleophilic carbon species to afford C-ribosides (via the corresponding hemiacetal). Treatment of 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone with stronger reducing agents, such as sodium borohydride, affords ring opened products with a stereo-defined poly-oxygenated carbon chain backbone.Formule :C26H26O5Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :418.48 g/mol2'-Deoxycytidine 5'-Monophosphate Hydrate
CAS :Formule :C9H14N3O7P·H2OMasse moléculaire :307.20 18.02Creatine monohydrate
CAS :Creatine monohydrate powers ATP for short, high-intensity activities in muscles and brain.Formule :C4H11N3O3Degré de pureté :98.32%Couleur et forme :White SolidMasse moléculaire :149.15N-[9-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6-oxo-1H-purin-2-yl]acetamide (Ganciclovir N-Acetate)
CAS :Couleur et forme :NeatDecitabine Impurity 42
CAS :Formule :C8H7ClO2Couleur et forme :White To Off-White SolidMasse moléculaire :170.59Ribavirin Impurity E
CAS :Formule :C15H16N4O6Couleur et forme :White To Off-White SolidMasse moléculaire :348.32Peramivir Impurity 2
CAS :Formule :C18H30N2O5Couleur et forme :White To Off-White SolidMasse moléculaire :354.45Decitabine Related Compound A (Mixture of Isomers)
CAS :Formule :C21H18Cl2O7Couleur et forme :White To Off-White SolidMasse moléculaire :453.28Palmitic Acid
CAS :Palmitic acid, stearic acid, their salts and estrsFormule :C16H32O2Couleur et forme :White Light Yellow PowderMasse moléculaire :256.24023Remdesivir related compound 5
CAS :Remdesivir related compound 5 is a plant extract that inhibits the growth of wheat. Remdesivir related compound 5 contains allelopathy, which is the ability to inhibit the growth of other plants by releasing substances from its roots or leaves. A study was conducted in which wheat seeds were treated with extracts of this plant and it was found that there was a significant decrease in the growth of the plants. This may be due to the inhibition of protein synthesis and cell division, as shown in other studies.Formule :C21H27N2O7PDegré de pureté :Min. 95%Masse moléculaire :450.42 g/molFavipiravir Impurity 12
CAS :Formule :C5H3F2N3OCouleur et forme :White To Off-White SolidMasse moléculaire :159.10Gemcitabine-13C-15N2 HCl
CAS :Formule :C813CH11F2N15N2O4·HClCouleur et forme :White To Off-White SolidMasse moléculaire :266.18 36.46Peramivir Impurity 4
CAS :Formule :C18H30N2O5Couleur et forme :White To Off-White SolidMasse moléculaire :354.455-(Methyl-d3)-Tetrahydrofolic Acid Calcium Salt
CAS :Formule :C20H20D3N7O6·CaMasse moléculaire :460.47 40.08Remdesivir impurity 8
Remdesivir impurity 8 is a metabolite of remdesivir, a drug product that belongs to the class of synthetic compounds. Remdesivir impurity 8 has been used as a research and development standard for HPLC analysis. It is also used as an impurity standard in pharmacopoeia and drug development. This impurity has shown natural activity in metabolism studies, but it is not known if this activity is due to the compound itself or an artifact from its synthesis.Formule :C30H39N6O8PDegré de pureté :Min. 95%Masse moléculaire :642.64 g/mol(1R,3R,4R)-Entecavir
CAS :Produit contrôléApplications (1R,3R,4R)-Entecavir is an isomeric impurity of Entecavir (E558900).Formule :C12H15N5O3Couleur et forme :NeatMasse moléculaire :277.28Peramivir Impurity 27
CAS :Formule :C12H19NO4Couleur et forme :White To Off-White SolidMasse moléculaire :241.29N-Nitroso Valaciclovir EP Impurity D-d5 (N-Nitroso Valacyclovir USP Related Compound D-d5)
Formule :C15H18D5N7O5Masse moléculaire :386.42Azacitidine USP Related Compound C Tosylate
CAS :Formule :C7H14N4O5·C7H8O3SMasse moléculaire :234.21 172.20Azathioprine EP Impurity D
CAS :Formule :C4H5N3O2SCouleur et forme :Orange SolidMasse moléculaire :159.169-Acetylazathioprine (9-Acetyl-6-[(1-methyl-4-nitroimidazol-5-yl)thio]purine)
CAS :Couleur et forme :Neat6-Pterinyl folic acid
CAS :6-Pterinyl folic acid is a chemical reagent that is used in the synthesis of pteridine derivatives. It is also used to prepare sulfates and esters of folic acid. 6-Pterinyl folic acid can be synthesized by reacting glutamic anhydride with trifluoroacetic acid and dimethylformamide. It reacts with sulfate ions to produce 6-pterinyl sulfate, which can then be hydrolyzed to release 6-pterinyl folic acid. The reagent can be used in the manufacture of fluoroquinolones, antibiotics that are used to treat a variety of bacterial infections including tuberculosis.Formule :C26H24N12O7Degré de pureté :Min. 95%Masse moléculaire :616.55 g/mol5-Chloro-1-methyl-4-nitro-1H-imidazole
CAS :Produit contrôléFormule :C4H4ClN3O2Couleur et forme :NeatMasse moléculaire :161.55Emtricitabine Impurity 30
CAS :Formule :C8H9FN2O4SCouleur et forme :Off-White SolidMasse moléculaire :248.23Emtricitabine Related Impurity 1
CAS :Formule :C8H9FN2O4SCouleur et forme :Off-White SolidMasse moléculaire :248.235’-Deoxy-5-fluorouridine
CAS :Produit contrôléImpurity USP Capecitabine Related Compound B Applications 5’-Deoxy-5-fluorouridine is a metabolite of the chemotherapeutic agent Capecitabine (C175650). 5’-Deoxy-5-fluorouridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes. References Ingle, J., et al.: Cancer, 67, 886 (1991); Harvey, J., et al.: J. Clin. Oncol., 17, 1474 (1999); Asai-Sato, M., et al.: Int. J. Cancer, 115, 539 (2005); Rastelli, F., et al.: Tumori, 94, 370 (2008);Formule :C9H11FN2O5Couleur et forme :NeatMasse moléculaire :246.195'-DFUR-13C5 (5'-Deoxy-5-fluorouridine, Doxifluridine-13C5)
CAS :Formule :C9H11FN2O5Masse moléculaire :251.22Nelarabine
CAS :Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.Formule :C11H15N5O5Degré de pureté :97.90% - 99.6%Couleur et forme :White SolidMasse moléculaire :297.27Ref: TM-T6603
1mg43,00€2mg57,00€5mg88,00€10mg140,00€25mg246,00€50mg437,00€100mg550,00€500mg1.159,00€1mL*10mM (DMSO)88,00€Melamine (Metformin EP Impurity D)
CAS :Formule :C3H6N6Couleur et forme :White To Off-White SolidMasse moléculaire :126.12Etravirine Impurity 14
CAS :Formule :C20H14BrN5OCouleur et forme :White To Off-White SolidMasse moléculaire :420.27Azathioprine
CAS :Azathioprine (BW 57-322), an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.Formule :C9H7N7O2SDegré de pureté :100% - 99.9%Couleur et forme :Pale Yellow Crystals From 50% Aq Acetone For The Treatment Of Rheumatoid Arthritis A Known CarcinogenMasse moléculaire :277.26N10-Nitroso Folic Acid Trifluoroacetate
CAS :Formule :C19H18N8O7·C2HF3O2Couleur et forme :Pale Yellow SolidMasse moléculaire :470.40 114.02Ribavirin Impurity 24 HCl
CAS :Formule :C4H6N4O2·HClCouleur et forme :White To Off-White SolidMasse moléculaire :142.12 36.46Lamivudine EP Impurity B
CAS :Formule :C8H11N3O3SCouleur et forme :Off-White SolidMasse moléculaire :229.25Fludarabine (Fludarabine Phosphate EP Impurity E)
CAS :Formule :C10H12FN5O4Couleur et forme :White To Off-White SolidMasse moléculaire :285.24Methylcobalamin Impurity 1
CAS :Formule :C22H20N2O2Couleur et forme :White To Off-White SolidMasse moléculaire :344.41Adefovir Dipivoxil
CAS :Formule :C20H32N5O8PCouleur et forme :White To Off-White SolidMasse moléculaire :501.48Decitabine (5-Aza-2'-Deoxy Cytidine)
CAS :Formule :C8H12N4O4Couleur et forme :White To Off-White SolidMasse moléculaire :228.215'-Deoxy-5'-iodo-2',3'-O-isopropylidene-5-chlorocytidine
Formule :C12H15ClIN3O4Masse moléculaire :427.62Aciclovir (Acyclovir) EP Impurity J
CAS :Formule :C14H16N10O4Couleur et forme :Off-White SolidMasse moléculaire :388.35Zidovudine EP Impurity B
CAS :Formule :C10H13ClN2O4Couleur et forme :White To Off-White SolidMasse moléculaire :260.68N,O-Diacetate Isoacyclovir
CAS :Produit contrôléImpurity Aciclovir EP Impurity M Applications An impurity of Acyclovir. Aciclovir EP Impurity M References Laskin, O., et al.: Clin. Pharmacok., 8, 187 (1983), Grass, G., et al.: Pharm. Res., 5, 372 (1988), Mahony, W., et al.: J. Biol. Chem., 263, 9285 (1988), Merino, V., et al.: J. Pharm. Sci., 84, 777 (1995),Formule :C12H15N5O5Couleur et forme :NeatMasse moléculaire :309.278Valaciclovir EP Impurity F Tosylate (Valacyclovir USP Related Compound F)
CAS :Formule :C7H15NO3·C7H8O3SCouleur et forme :White To Off-White SolidMasse moléculaire :161.20 172.20Azathioprine EP Impurity G (Thiamiprine)
CAS :Formule :C9H8N8O2SCouleur et forme :Yellow SolidMasse moléculaire :292.28Sofosbuvir Impurity 34 Disodium Salt (GS-606965 Disodium Salt)
CAS :Formule :C10H12FN2O8P·2NaMasse moléculaire :384.16 2*22.99Peramivir Impurity 5
CAS :Formule :C20H36N2O6Couleur et forme :White To Off-White SolidMasse moléculaire :400.52Favipiravir Impurity 27
CAS :Formule :C5H5N3O3Couleur et forme :White To Off-White SolidMasse moléculaire :155.11Gemcitabine elaidate
CAS :Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, withFormule :C27H43F2N3O5Couleur et forme :SolidMasse moléculaire :527.641-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid
CAS :1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid (1bRT) is an amide that inhibits the growth of viruses by inhibiting the viral enzyme thiosemicarbazide. It has been shown to be active against specific viruses such as HIV and retroviruses. 1bRT is used to treat lung diseases caused by viruses, including bronchiolitis, pneumonia, and pulmonary fibrosis. It also has antibacterial properties. Studies have shown that 1bRT reduces the number of bacteria in body fluids and helps to prevent respiratory infections and other bacterial infections in people with weakened immune systems due to AIDS or cancer treatment.Formule :C8H11N3O5Degré de pureté :Min. 95%Masse moléculaire :229.19 g/molCytosine
CAS :Cytosine is a pyrimidine nucleic acid base; its deamination can cause mutations in leukemia and cancer.Formule :C4H5N3ODegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :111.12'-Deoxy-2',2'-difluorocytidine 5'-triphosphate sodium, 10 mM aqueous solution
CAS :2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate sodium, 10 mM aqueous solution is an analytical standard that is used in metabolism studies and as an impurity in some pharmaceuticals. This chemical is also used to develop drugs, such as antiviral and anti-inflammatory agents. 2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate sodium, 10 mM aqueous solution has a CAS number of 1440537-37-0 and the molecular weight of 463.88 g/mol. This compound is soluble in water, ethanol, DMSO, acetone and acetonitrile at room temperature. The purity for this compound is > 99%.Formule :C9H14F2N3O13P3•NaxDegré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :503.14 g/molThymidine-5’-triphosphate Tetrasodium Salt
CAS :Formule :C10H13N2O14P3·4NaMasse moléculaire :478.14 4 22.99Sofosbuvir Impurity 49 (GS-566500) Ditriethylamine Salt
CAS :Formule :C13H19FN3O9P·2Et3NCouleur et forme :White To Off-White SolidMasse moléculaire :411.28 2*101.19Ribavirin Impurity 1
CAS :Formule :C4H5N3O2Couleur et forme :White To Off-White SolidMasse moléculaire :127.10Oxiracetam
CAS :Formule :C6H10N2O3Couleur et forme :White To Off-White SolidMasse moléculaire :158.161-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxylic Acid
CAS :Produit contrôléFormule :C8H11N3O6Couleur et forme :NeatMasse moléculaire :245.19Remdesivir impurity 1
CAS :Remdesivir impurity 1 is a drug product, analytical and Metabolism studies. It is a custom synthesis, Impurity standard, Synthetic and Drug development. Remdesivir impurity 1 is an API impurity that is a natural and has CAS No. 1355049-95-4. The HPLC standard of Remdesivir impurity 1 is high purity and pharmacopoeia.Formule :C12H13N5O4Degré de pureté :Min. 95%Masse moléculaire :291.26 g/molEmtricitabine Impurity 32
CAS :Formule :C8H9FN2O4SCouleur et forme :White To Off-White SolidMasse moléculaire :248.23Anti-Folic acid Antibody (2W564)
Anti-Folic acid Antibody (2W564) is a Mouse antibody targeting Folic acid. Anti-Folic acid Antibody (2W564) can be used in ELISA.Degré de pureté :>95%Couleur et forme :Odour LiquidRibavirin
CAS :Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.Formule :C8H12N4O5Degré de pureté :98.53% - 99.83%Couleur et forme :Less Solid Colourless SolidMasse moléculaire :244.2
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